“…In each reprogramming window, a unique set of mechanisms regulates DNA methylation erasure and re-establishment. Recent advances have uncovered roles for the TET3 hydroxylase and passive demethylation, together with base excision repair (BER) and the elongator complex, in methylation erasure from the zygote. …”
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“…Intergenerational transmission of epigenetic memory through the germline, in the form of DNA methylation, has been proposed; however, in mammals this is largely prevented by extensive epigenetic erasure during germline definition. Here we report that, unlike mammals, the continuously-defined ‘preformed’ germline of zebrafish does not undergo genome-wide erasure of DNA methylation during development. …”
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“…<!--HTML-->Our large erasure coded ceph cluster is used by the four large LHC experiments for scientific data storage, providing 30PB of usable storage and averaging a 30GB/s read rate to the analysis cluster. …”
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“…More generally, it shows that defect interactions can lead to ``defect erasure'' in phase transitions and that this can be relevant to early universe physics.…”
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“…We examined DNA methylation at nonpromoter, intergenic sequences in purified prenatal and postnatal germ cells isolated from wildtype mice and mice deficient in the DNA methyltransferase cofactor DNMT3L. Erasure of the parental DNA methylation pattern occurred by 13.5 days post coitum (dpc) with the exception of approximately 8% of loci demonstrating incomplete erasure. …”
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“…These outcomes require the catalytic activity of BAP1, indicating that they are downstream consequences of H2AK119Ub erasure. In bone marrow precursors, expression of truncated ASXL1–BAP1 complex cooperates with TET2 loss-of-function to increase differentiation to the myeloid lineage in vivo. …”
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“…MSCs can be rejuvenated by reprogramming into induced pluripotent stem cells (iPSCs), which is associated with complete erasure of age- and senescence-associated DNA methylation (DNAm) patterns. …”
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“…Cache-A Replica On Modification (CAROM) is a hybrid file system that gets combined benefits from both the replication and erasure codes to reduce access latency and bandwidth consumption. …”
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“…In addition, EOS must offer a sufficient data protection through erasure coding for the data until it is copied to archival storage. …”
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“…HMMN (150 μg/ml) inhibited the biofilm formation of P. aeruginosa PAO1 by 28.24%. The erasure rate of the formed biofilm reached 17.03%. …”
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“…It provides detailed theoretical treatments and experimental analyses of such phenomena as quantum erasure, quantum lithography, multi-atom entanglement, quantum beats, control of decoherence, phase control of quantum interference, coherent population trapping, electromagnetically induced transparency and absorption, lasing without inversion, subluminal and superluminal light propagation, storage of photons, quantum interference in phase space, interference and diffraction of cold atoms, and interference between Bose-Einstein condensates. …”
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“…The spermatocytic seminomas showed uniparental paternal imprinting while testicular teratomas exhibited partial imprinting erasure. Somatic imprinting in type II GCTs might indicate a cell of origin after global demethylation but before imprinting erasure. …”
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“…In order of increasing seriousness, outcomes were: no impairment (of ability to practise), impairment, suspension (of right to practise), or erasure (its loss). This gave adjusted odds ratios (OR) for: age, race, sex, whether physicians first qualified domestically or internationally, area of practice (e.g. …”
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“…DNA methylation (5mC) is central to cellular identity. The global erasure of 5mC from the parental genomes during preimplantation mammalian development is critical to reset the methylome of gametes to the cells in the blastocyst. …”
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“…More importantly, these DMRs evaded offspring embryonic reprogramming through erasure and subsequent reestablishment, but not via un-erasure way. …”
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“…This would necessarily entail confronting the fragmentation of governance and erasure of accountability promoted by corporate designed multi-stakeholderism, and democratizing multilateralism through genuine participation of rights holders, public scrutiny and participatory science. …”
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“…From the perspective of the legitimate parties that share a secret key, the degradation appears as a transmission of the ciphertext through a binary erasure channel. On the other hand, from the perspective of an attacker the degradation appears as a transmission of the ciphertext over a binary deletion channel. …”
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“…How to explore the traumatic event in a patient and propose its erasure? Study the events that can cause trauma and the different approaches to psychological trauma in dental care. …”
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“…Altogether, our results suggest that Dnmt1 is actively retained in the cytoplasm, which prevents binding to its DNA substrate in the nucleus and thereby contributes to the erasure of gamete-specific epigenetic information during early mammalian development.…”
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“…Here we show by means of Landauer’s principle that memory effects control the amount of work extraction by erasure in presence of realistic environments.…”
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