Mostrando 81 - 100 Resultados de 1,838 Para Buscar '"Eros"', tiempo de consulta: 0.22s Limitar resultados
  1. 81
  2. 82
    “…Ero1-α and PDI were found to constitute a regulatory hub, whereby PDI induced conformational flexibility in an Ero1-α shuttle cysteine (Cys99) facilitated intramolecular electron transfer to the active site. …”
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  3. 83
    “…A reanalysis of NEAR X‐ray/gamma‐ray spectrometer (XGRS) data provides robust evidence that the elemental composition of the near‐Earth asteroid 433 Eros is consistent with the L and LL ordinary chondrites. …”
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  5. 85
    “…Mechanistically and functionally, NFIB directly increases expression of the oxidoreductase ERO1A, which enhances HIF1α‐VEGFA‐mediated angiogenesis and colonization, the last and fatal step of the metastatic cascade. …”
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  6. 86
    “…In summary, we identified a new scaffold that shows specificity for ERO1α compared to that for the closely related paralog ERO1β or the FAD-containing enzyme LSD-1 that can be used as a tool compound for the inhibition of ERO1α to allow for pharmacological validation of the role of ERO1α in cancer.…”
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  7. 87
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  9. 89
    “…In this paper, we will consider the interactions of Ero1 with PDI family proteins and chaperones, highlighting the effect that redox flux has on Ero1 partnerships. …”
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  10. 90
    “…Following previous studies that identified endoplasmic reticulum oxidoreductin 1-α (ERO1L) as a potential marker for gastric cancer, we investigated the functional role of ERO1L in gastric cancer. …”
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  12. 92
    “…BACKGROUND: Endoplasmic reticulum oxidoreductase 1 alpha (ERO1L) serves as an effector for tumor growth in human malignancies. …”
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  13. 93
    “…Endoplasmic reticulum (ER) stress also leads tumor cells to thrive and spread by inducing a transcriptional and translational program, the Unfolded Protein Response (UPR), aimed at restoring ER homeostasis. We studied ERO1 alpha (henceforth ERO1), a protein disulfide oxidase with the tumor-relevant characteristic of being positively regulated by both ER stress and hypoxia. …”
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  14. 94
    “…BACKGROUND: The endoplasmic reticulum oxidoreductin-1-like (ERO1L) gene encodes an endoplasmic reticulum luminal localized glycoprotein known to associated with hypoxia, however, the role of ERO1L in shaping the tumor immune microenvironment (TIME) is yet to be elucidated in lung adenocarcinoma (LUAD). …”
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  16. 96
    por Palacios, Oscar, 1942-
    Publicado 1978
    Libro
  17. 97
    Tesis Libro
  18. 98
  19. 99
    por Tsai, Billy, Rapoport, Tom A.
    Publicado 2002
    “…We show that upon oxidation of the COOH-terminal disulfide bond in PDI by the enzyme Ero1, the A1 chain is released. Both yeast Ero1 and the mammalian Ero1α isoform are active in this reaction. …”
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