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2021por Dhingra, Seebu, Rajesh, Gururaghavendran, Rao, Ashwini, Pai, Umesh Y., Shenoy, Ramya, Pai, Mithun“…PURPOSE: Presence of functional tooth units is essential for preserving masticatory function among individuals. Representing the essence of health promotion practice, demand to measure varied evaluation outcomes is highlighted. …”
Publicado 2017
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2022por Muhammed, Kurfi Abubakar, Umeh, Kalu Nnena, Nasir, Sambo M., Suleiman, Idris Hadejia“…The essence of primary health care is the provision of essential health services and commodities to individuals and communities using available, acceptable and sustainable resources. …”
Publicado 2013
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2023“…At the heart of the challenge of encouraging more widespread adoption of the TCB is the question: what is the best way to introduce the TCB technology, and all its attendant practices and opportunities, to smallholder farmers. In essence, a challenge of community or stakeholder engagement (CE). …”
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2024Publicado 2017“…What then would be the most effective therapeutic approaches to treat what in essence can be regarded as a whole brain malignancy, since even a surgical resection of greater than 99% of tumor tissues is invariably associated with recurrence? …”
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2025“…This highlights the misleading conclusions that can be reached when relying on a single method that is not a gold standard; this is the essence of Segal’s Law: an individual with one watch knows what time it is but an individual with two is never sure. …”
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2026por Black-Schaffer, W. Stephen, Morrow, Jon S., Prystowsky, Michael B., Steinberg, Jacob J.“…Building on the strengths of existing programs, we propose a redesign of pathology residency training that will meet (and encourage) a continuing evolution of American Board of Pathology and Accreditation Council for Graduate Medical Education requirements, reduce the time to readiness for practice, and produce more effective, interactive, and adaptable pathologists. The essence of this new model is clear definition and acquisition of core knowledge and practice skills that span the anatomic and clinical pathology continuum during the first 2 years, assessed by competency-based metrics with emphasis on critical thinking and skill acquisition, followed by individualized modular training with intensively progressive responsibility during the final years of training. …”
Publicado 2016
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2027“…CONCLUSION AND IMPLICATIONS: The essence of parents’ comments was the experience of authorities and societal actors trying to push the responsibility onto someone else. …”
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2028por Vogel, Jürgen, Auinger, Andreas, Riedl, René, Kindermann, Harald, Helfert, Markus, Ocenasek, Helmuth“…Our findings have implications for the design of self-management approaches in a patient rehabilitation setting. In essence, the use of smart wearables can prolong the success of the rehabilitation outside of the organized rehabilitation setting.…”
Publicado 2017
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2029por Naji, Mohammad, Aleyasin, Ashraf, Nekoonam, Saeid, Arefian, Ehsan, Mahdian, Reza, Amidi, Fardin“…The heterogeneous and multifactorial essence of polycystic ovary syndrome (PCOS) renders a remarkable significance to microRNAs (miRNAs). …”
Publicado 2017
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2030por Teves, Joji M. Y., Bhargava, Vedanshi, Kirwan, Konner R., Corenblum, Mandi J., Justiniano, Rebecca, Wondrak, Georg T., Anandhan, Annadurai, Flores, Andrew J., Schipper, David A., Khalpey, Zain, Sligh, James E., Curiel-Lewandrowski, Clara, Sherman, Scott J., Madhavan, Lalitha“…Moreover, the PD fibroblasts accumulated higher levels of reactive oxygen species (ROS) coupled with lower cell viability upon UVA treatment. In essence, these studies highlight primary skin fibroblasts as a patient-relevant model that captures fundamental PD molecular mechanisms, and supports their potential utility to develop diagnostic and prognostic biomarkers for the disease.…”
Publicado 2018
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2031por Martins, Filipa, Marafona, Ana M., Pereira, Cátia D., Müller, Thorsten, Loosse, Christina, Kolbe, Katharina, da Cruz e Silva, Odete A. B., Rebelo, Sandra“…This interaction was validated as well as the interaction with GAP-43 and synaptophysin. In essence, the resulting BRI2 brain interactome, associates this protein with neurite outgrowth and neuronal differentiation, as well as synaptic signalling and plasticity. …”
Publicado 2018
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2032por White, Paul, Saketa, Salanieta, Johnson, Eliaser, Gopalani, Sameer V., Edward, Eliashib, Loney, Charles, Mercier, Alize, Toatu, Tebuka, Wojcik, Richard, Lewis, Sheri, Hoy, Damian“…The surveillance was implemented using the web-based Suite for Automated Global Electronic bioSurveillance Open-ESSENCE (SAGES-OE) application that was customized for the Games. …”
Publicado 2018
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2033“…Love is in the center of the model and rehabilitation of love in its broadest sense is, accordingly, the essence of holistic medicine. To know yourself, your purpose of life (life mission) and talents, and taking these into full use and becoming coherent with life inside and reality outside is what human life is essentially about. …”
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2034“…The patient's life, now and in the future, is in the palm of your hand, and to assume this huge responsibility, the physician must be anxious and careful about the quality of the medical record. Much too often, the essence of the session is nowhere to be found in the case record, so most of the generated value is lost between consultations.…”
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2035“…According to the life mission theory, the essence of man is his purpose of life, which comes into existence at conception. …”
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2036“…A life-long learning approach cannot be forced, since it is in essence an internally driven process. Nurse educators can, however, act as role models to empower their students to become independent learners by modelling their own self-directed learning and applying a number of techniques in supporting their students in becoming ready for self-directed learning. …”
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2037por Oberemok, Volodymyr V., Laikova, Kateryna V., Repetskaya, Anna I., Kenyo, Igor M., Gorlov, Mikhail V., Kasich, Igor N., Krasnodubets, Alisa M., Gal’chinsky, Nikita V., Fomochkina, Iryna I., Zaitsev, Aleksei S., Bekirova, Viktoriya V., Seidosmanova, Eleonora E., Dydik, Ksenia I., Meshcheryakova, Anna O., Nazarov, Sergey A., Smagliy, Natalya N., Chelengerova, Edie L., Kulanova, Alina A., Deri, Karim, Subbotkin, Mikhail V., Useinov, Refat Z., Shumskykh, Maksym N., Kubyshkin, Anatoly V.“…Over the last 50 years, planned and realized applications in the field of antisense and nucleic acid nanotechnologies have produced astonishing results and posed new challenges for further developments, exemplifying the essence of the post-genomic era. Today the majority of ASOs are chemically modified and/or incorporated within nanoparticles to enhance their stability and cellular uptake. …”
Publicado 2018
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2038“…Given that α-synuclein is a major protein constituent of Lewy body pathology, a hallmark neuropathological feature in Parkinson's disease, these findings could open up new avenues for pharmacological intervention strategies aimed at alleviating the burden of α-synucleinopathies in the Parkinsonian brain. In essence, the literature reviewed herein supports our hypothesis of a tripartite neuroprotective role for noradrenaline in combating PD-related neuropathology and motor dysfunction via (1) inhibiting nigral microglial activation & pro-inflammatory mediator production, (2) promoting the synthesis of neurotrophic factors from midbrain astrocytes and (3) downregulating α-synuclein gene expression and protein abundance in a β(2)-AR-dependent manner. …”
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2039por Belal, Shah Ahmed, Sivakumar, Allur Subramaniyan, Kang, Da Rae, Cho, Sangbuem, Choe, Ho Sung, Shim, Kwan Seob“…We also analyzed the mRNA expression of lipid metabolizing genes such as peroxisome proliferator receptor alfa (PPARα), peroxisome proliferator receptor gamma (PPARγ), acyl-CoA oxidase (ACOX), lipoprotein lipase (LPL), carnitine palmitoyl transferase (CPT-1), and fatty-acid binding protein4 (FABP4), which were upregulated in LA or OA treated cells compared to the control group. In essence, LA and OA alone promote the cell proliferation without any apoptosis and necrosis, which might upregulate the lipid metabolism related gene expressions, and increase fatty-acid oxidation in the BSCs’ lipid metabolism.…”
Publicado 2018
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2040por Hernández, Félix, Castiglioni, Sara, Covaci, Adrian, de Voogt, Pim, Emke, Erik, Kasprzyk‐Hordern, Barbara, Ort, Christoph, Reid, Malcolm, Sancho, Juan V., Thomas, Kevin V., van Nuijs, Alexander L.N., Zuccato, Ettore, Bijlsma, Lubertus“…The predominance of liquid chromatography coupled to tandem mass spectrometry to quantify target IDBs and the essence to produce reliable and comparable results is illustrated. …”
Publicado 2016
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