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1341“…Further, MSP1 induced phosphorylation of some of the key proteins including respiratory burst oxidase homologue-D (RBOHD), mitogen-activated protein kinase kinase kinase-1 (MEKK1), mitogen-activated protein kinase-3/6 (MPK3/6), calcium-dependent protein kinase (CDPK) and calmodulin (CaM) suggest activation of PAMP-triggered immunity (PTI) in response to MSP1 treatment. In essence, our results further support the functioning of MSP1 as a PAMP and provide an overview of the MSP1 induced signaling in rice leaves.…”
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1342por Dzhemilev, Usein M., Khuzin, Artur A., Akhmetov, Arslan R., D’yakonov, Vladimir A., Dzhemileva, Lilya U., Yunusbaeva, Milyausha M., Tuktarov, Airat R.“…[Image: see text] This paper describes the authors’ preliminary studies directed toward the possibility of the practical implementation of the idea to design efficient antitumor drugs based on hybrid molecules composed of fullerene C(60) and quadricyclanes. The essence of the proposed idea is that these hybrid molecules are able to cleave DNA owing to the fullerene moiety they contain and to simultaneously thermally affect tumor cells via cleavage of the carbon–carbon bond in quadricyclanes under the action of Pd and Pt ions. …”
Publicado 2019
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1343“…The history of philosophy gives us many different accounts of a true self, connecting it to the essence of what a person is, the notion of conscience, and the ideal human being. …”
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1344“…CONCLUSION: In summary, the essence of reducing anterolateral rotatory knee instability begins and ends with a well-done, anatomic ACL reconstruction, which may be performed with consideration of extra-articular tenodesis in a select group of patients.…”
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1345por Wang, Huiqing, Wang, Jingjing, Dong, Chunlin, Lian, Yuanyuan, Liu, Dan, Yan, Zhiliang“…Incorporating multiple similarity measures for drugs and targets is of essence for improving the accuracy of prediction of DTIs. …”
Publicado 2020
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1346por Wang, Jie, Gao, Yong, You, Zhiming, Fan, Jiakun, Zhang, Jing, Wang, Sheng, Xu, Zhanglian“…Before the installation of laser processed aluminum alloy, surface cleaning is of the essence to reduce the contaminations of ultra-high vacuum systems for providing appropriate pressure for beam operation consequently. …”
Publicado 2020
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1347“…Though this data was in essence generated to assess which labels are best suited for SOFI imaging, it can be used as a benchmark for further development of the SOFI algorithm, or for the development of other super-resolution imaging modalities that benefit from similar input data.…”
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1348“…METHODS: Amlodipine besylate film was prepared by solvent casting method by using hydroxypropyl methylcellulose (HPMC) as film formers, crospovidone as superdisintegrant with Varian concentration F1 (2%), F2 (4%), F3 (6%) and F4 (8%), PEG 400 as plasticizer, sucralose and sorbitol as sweetener, citric acid as saliva stimulation, and grape essence as flavoring and coloring agent. Characteristics of films include organoleptic, weight uniformity, film thickness, surface pH, swelling, uniformity of content, time of disintegration, and dissolution. …”
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1349por Tran The, Jessica, Ansermet, Jean-Philippe, Magistretti, Pierre, Ansermet, François“…Our research aims to demonstrate that the theory of the death drive does not represent a complete change in direction for Freud. It is present, in essence, in his earliest work, to the extent that the “principle of inertia” described in 1895 in A Project for a Scientific Psychology (Freud, 1895) can be seen as a precursor to the death drive. …”
Publicado 2020
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1350“…Medicinal property, which is closely related to drug chemical profiling, is the essence of traditional Chinese medicine (TCM) theory and has always been the focus of modern Chinese medicine. …”
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1351“…In this paper, we describe the organization of the project and the culture created by its multidisciplinary essence. We discuss the main thematic sections of the project and the strategy adopted to optimize the integration of various scientific fields into a common objective: to obtain crystal structures of the widest variety of RNA virus replication enzymes documented and validated as potential drug targets. …”
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1352por Zhang, Yunzhan, Chen, Xu, Gong, Lin, Li, Danyan, Dai, Yun-kai, Lan, Shaoyang, Luo, Qi, Chen, Bin, Chen, Weijing, Li, Ruliu, Hu, Ling“…Traditional Chinese medicine (TCM) syndrome is the essence of TCM, reflecting the state of whole body. …”
Publicado 2020
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1353por Flint-O’Kane, Meriel, von Dadelszen, Peter, Makanga, Prestige Tatenda, Sevene, Esperança, Roca, Anna, Dukes, Peter, Hinrichs-Krapels, Saba, Craik, Rachel, Magee, Laura A., Temmerman, Marleen“…Best practice principles outlined in an ESSENCE on Health Research report have been considered in relation to the PRECISE Network capacity-building activities described in this paper. …”
Publicado 2020
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1354“…Theoretical analysis with corresponding experiment in microwave band are introduced for better insights into physical essence of the double-peaks A-EIT.…”
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1355por Song, Juha, Han, Dohyun, Lee, Heonyi, Kim, Da Jung, Cho, Joo-Youn, Park, Jae-Hak, Seok, Seung Hyeok“…Further, phosphorylation events in multiple pathways, including MAPKK and Wnt/β-catenin signalings, were identified as involved in LPS-triggered pathobiology. In essence, our findings reveal multiple integrated signals exerted by RPE under inflammation and are expected to give insight into the development of therapeutic interventions for RPE disorders.…”
Publicado 2020
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1356por Wong, Chin-Chean, Huang, Yu-Min, Chen, Chih-Hwa, Lin, Feng-Huei, Yeh, Yi-Yen, Bai, Meng-Yi“…For in vitro study, the essence portion of PRF was determined through bioluminescent assay. …”
Publicado 2020
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1357por Wu, Dean, Yang, Cheng-Chang, Chen, Kuan-Yu, Lin, Ying-Chin, Wu, Pei-Jung, Hsieh, Pei-Hsiu, Nakao, Yoshihiro, Ow, Mandy Y. L., Hsieh, Yi-Chen, Hu, Chaur-Jong“…Cognitive aging might begin at middle adulthood, the period particularly vulnerable to stress in lifespan. Essence of chicken (EOC) has consistently demonstrated its beneficial effects on various cognitive domains as nutritional supplementation. …”
Publicado 2020
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1358“…Furthermore, NaAs could interfere with QS-regulated bioluminescence in V. campbellii, suggesting the QS-inhibitory activity largely determines the protective effect of NaAs toward the brine shrimp. In essence, due to the potent anti-virulence effects observed in in vitro studies and the clinical brine shrimp-V. campbellii infection model, NaAs constitute a promising novel strategy for the control of V. campbellii infections in aquaculture.…”
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1359“…These findings not only contribute to understanding the essence of nanozyme catalytic activity but also suggest a practically feasible method to regulate the catalytic activity of IONzyme.…”
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1360por Benkeser, David, Díaz, Iván, Luedtke, Alex, Segal, Jodi, Scharfstein, Daniel, Rosenblum, Michael“…Time is of the essence in evaluating potential drugs and biologics for the treatment and prevention of COVID-19. …”
Publicado 2020
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