“…Finally, animal models of idiosyncratic DILI mimicking human immune and genetic features are not available and further search likely will be unsuccessful. In essence and based on cases of DILI with verified diagnosis using RUCAM for causality evaluation, there is now substantial direct evidence that immune mechanisms and genetics can account for idiosyncratic DILI by many but not all implicated drugs, which may help understand the mechanistic background of the disease and contribute to new approaches of therapy and prevention.…”
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“…This study adds to the literature by revealing several possible vulnerability factors associated with VC fatigue. In essence, the present work sheds light on the complex association between autistic traits and VC fatigue. …”
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“…Importantly from a safety viewpoint, R-421 failed to infect malignant cells that do not harbor nectin4 gene amplification/overexpression, whose expression level was moderate-to-low. In essence, there was a net threshold value below which cells were spared from infection, irrespective of whether they were malignant or normal; the only cells that R-421 targeted were the malignant overexpressing ones. …”
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“…Yet there are many models of service integration that can promote more collaborative care between psychiatrists and medical specialists, including some which have been taken to scale. DISCUSSION: In essence, clinical teams in children’s hospitals require more collaborative approaches that facilitate early recognition and treatment of the psychological aspects of illness as an integral part of patient‐centred, family‐focussed paediatric care, rather than as something that is bolted on when things go wrong. …”
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“…Second, being adjacent to marginal and core provinces will maintain the province’s centrality index category to the greatest extent, while being adjacent to sub-core and general provinces leads the province to gain more opportunities for upward transfer. Third, the essence of the interprovincial economic resilience subordination linkage in China is manifested in the aggregation of city clusters or economic circles. …”
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“…These waves can carry different orbital angular momentum and spin angular momentum, and therefore, they feature the ability to carry multiple orthogonal modes at the same frequency due to spatial structure of the phase and polarization. In essence, high data rate channels can be developed using such waves. …”
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“…Our hybrid structure design, in combination with an optical simulation system, not only facilitates rapid acquisition of optimal parameters for highly uniform and efficient color conversion in μ-LED displays but also expands the color gamut to achieve 128.2% in the National Television Standards Committee (NTSC) space and 95.8% in the Rec. 2020 standard. In essence, this research outlines a promising avenue towards the development of bespoke, high-performance μ-LED displays.…”
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“…Menstrual irregularity, anovulation, and many cosmetic issues faced by PCOS patients endanger the essence of being a woman and may have a deleterious impact on their health-related quality of life (HRQOL). …”
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“…Therefore, employing this essence from AI, we designed an optimum aging route in which we attained an outperformed 0.2% proof stress to AI-designed NIA routes.…”
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“…Biomedical engineering often aims to harness and drive such activity in vitro, in bioreactors to study cell disease and differentiation, and often in three-dimensional (3D) formats with the help of biomaterials, with most of these approaches adopting scaffold-free self-assembling strategies to create 3D tissues. In essence, this is the casting of gels which self-assemble in response to factors such as temperature or pH and have capacity to harbor cells during this process without imparting toxicity. …”
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“…CONCLUSION: Nurses are integral in the provision of spiritual care for cancer patients from diagnosis up until the end of life. The essence of spiritual activities gives patients a distraction and an escape from their pain and predicament thus improving their quality of life. …”
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“…BACKGROUND: Screening for diabetic retinopathy in the community without compromising the routine work of ophthalmologists at hospitals is the essence of teleophthalmology. This study was aimed at investigating the efficacy of teleophthalmology practice for screening diabetic retinopathy from 2012 to 2020. …”
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“…In addition, an increase in per capita income improves the environmental quality but the doubling of income per capita triggers environmental degradation, thus invalidating the EKC hypothesis in the examined panel economies. In essence, these countries have not reached the supposed turning point at which income growth can yield desirable emission mitigation effects. …”
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“…This approach combines a small subset of the 360 angular views (limited views approach) with a computationally inexpensive proxy solution (real-time forward model) that brings the essence of the physics to obtain a real-time high-fidelity solution at all angular views but at a fraction of the computational cost. …”
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“…However, primary care is also considered as ground-zero for the rise in healthcare consumerism. METHODS: In essence, consumerism refers to increasing expectations from patients (consumers) to be more active participants in decisions related to their healthcare. …”
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“…We reveal that the nonlinear vortical flow field over time and parameter space can be compressed to only three variables with a lift-augmented autoencoder while holding the essence of the original high-dimensional physics. …”
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“…However, there is no correlation between mean corpuscular haemoglobin concentration and outcomes, indicating complex interactions between haematological markers and outcomes. In essence, this study underlines the importance of age in COVID-19 mortality, provides novel insights into platelet counts, and emphasises the complexity of the relationships between haematological parameters and disease outcomes.…”
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“…You-Gui-Yin (YGY) is a classic prescription for warming up kidney-Yang and filling in kidney essence in traditional Chinese medicine, and has been used to treat osteonecrosis of the femoral head (ONFH) effectively. …”
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“…Our results shed new light on the transition from quantum to classical electrodynamics, enabling us to employ the essence of the wave-particle duality of both light and electrons in quantum measurement for exploring and applying many quantum and classical light–matter interactions.…”
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“…Through decision plots, a detailed error analysis was conducted, contrasting feature importance for correctly versus incorrectly classified samples. In essence, our pipeline emphasizes the importance of harmonizing AutoML and XAI, facilitating both simplified ML application and improved interpretability in metabolomics data science. …”
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