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  1. 5121
    por Papp, Zoltán, Agostoni, Piergiuseppe, Alvarez, Julian, Bettex, Dominique, Bouchez, Stefan, Brito, Dulce, Černý, Vladimir, Comin-Colet, Josep, Crespo-Leiro, Marisa G, Delgado, Juan F, Édes, Istvan, Eremenko, Alexander A, Farmakis, Dimitrios, Fedele, Francesco, Fonseca, Cândida, Fruhwald, Sonja, Girardis, Massimo, Guarracino, Fabio, Harjola, Veli-Pekka, Heringlake, Matthias, Herpain, Antoine, Heunks, Leo MA, Husebye, Tryggve, Ivancan, Višnja, Karason, Kristjan, Kaul, Sundeep, Kivikko, Matti, Kubica, Janek, Masip, Josep, Matskeplishvili, Simon, Mebazaa, Alexandre, Nieminen, Markku S, Oliva, Fabrizio, Papp, Julius-Gyula, Parissis, John, Parkhomenko, Alexander, Põder, Pentti, Pölzl, Gerhard, Reinecke, Alexander, Ricksten, Sven-Erik, Riha, Hynek, Rudiger, Alain, Sarapohja, Toni, Schwinger, Robert HG, Toller, Wolfgang, Tritapepe, Luigi, Tschöpe, Carsten, Wikström, Gerhard, von Lewinski, Dirk, Vrtovec, Bojan, Pollesello, Piero
    Publicado 2020
    “…In the ensuing 20 years, this distinctive inodilator, which enhances cardiac contractility through calcium sensitisation and promotes vasodilatation through the opening of adenosine triphosphate-dependent potassium channels on vascular smooth muscle cells, has been approved in more than 60 jurisdictions, including most of the countries of the European Union and Latin America. Areas of clinical application have expanded considerably and now include cardiogenic shock, takotsubo cardiomyopathy, advanced heart failure, right ventricular failure and pulmonary hypertension, cardiac surgery, critical care and emergency medicine. …”
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    Levosimendan Efficacy and Safety: 20 years of SIMDAX in Clinical Use
  2. 5122
    “…TRIAL REGISTRATION: European Union Drug Regulating Authorities Clinical Trials Database: EudraCT: 2004–003863-59 (registration date 05/MAR/2004), EudraCT 2006–001162-17 (registration date 17-MAR-2006), EudraCT: 2007–002489-37 (registration date 12-JUN-2007), EudraCT: 2007–002490-31 (registration date 12-JUN-2007), EudraCT: 2010–024029-19 (registration date 23-NOV-2010).…”
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    Effect of food on the pharmacokinetics of omeprazole, pantoprazole and rabeprazole
  3. 5123
    “…As a consequence, an Emergency Use Authorization (EUA) from the FDA has allowed importation of N95-type masks manufactured to international standards; these include KN95 masks from China and FFP2 masks from the European Union. METHODS: We conducted a survey of mask in the inventory of major academic medical centers in Boston, MA to determine provenance and manufacturer. …”
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    Assessing the quality of nontraditional N95 filtering face-piece respirators available during the COVID-19 pandemic
  4. 5124
    “…Thus, sub-therapeutic antibiotics have been used to alleviate these detrimental effects; however, it has been shown that these practices create microbial resistance and cross-resistance to other microorganisms. Although the European Union banned antibiotic growth promoters (AGP), many countries in the world still use them widely. …”
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    Evaluation of Oral Administration of Lactobacillus plantarum CAM6 Strain as an Alternative to Antibiotics in Weaned Pigs
  5. 5125
    “…Yet, much investment and development is still needed to fulfil the goals for renewable energy generation defined by the Portuguese government and the European Union, in order to decarbonize energy generation and reduce energy dependence. …”
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    Decentralized electricity storage evaluation in the Portuguese context
  6. 5126
    “…Over this period, there has been considerable turnover in the pesticides used. The European Union (including Great Britain until 2020) has restricted or banned many pesticides for agricultural use, including organophosphates and carbamates. …”
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    Identifying agricultural pesticides that may pose a risk for birds
  7. 5127
    “…FUNDING: British Heart Foundation, European Union (H2020), Leducq Foundation.…”
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    Reduced left atrial cardiomyocyte PITX2 and elevated circulating BMP10 predict atrial fibrillation after ablation
  8. 5128
    “…The study site is situated in Western Poland (52°25′ N, 15°32′ E) and is ranked within the top 10 largest hibernation sites in the European Union. The number of hibernating bats in the winter exceeds 39,000 individuals of 12 species, with M. myotis being the most common one. …”
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    A Culture-Based ID of Micromycetes on the Wing Membranes of Greater Mouse-Eared Bats (Myotis myotis) from the “Nietoperek” Site (Poland)
  9. 5129
    “…INTRODUCTION: The European Reference Network (ERN) ReCONNET is the ERN aimed at improving the management of rare and complex connective tissue and musculoskeletal diseases (rCTDs) across the European Union (EU). In the mission of ERN ReCONNET, clinical practice guidelines (CPGs) play a crucial role, representing a valid tool towards the harmonisation of the management of rCTDs while improving effectiveness and quality of care delivered to patients. …”
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    Clinical practice guidelines adherence, knowledge and awareness in rare and complex connective tissue diseases across Europe: results from the first ERN ReCONNET survey
  10. 5130
    “…BACKGROUND: This study presents perceptions of the harmfulness of electronic cigarettes (e-cigarettes) relative to combustible cigarettes among smokers from six European Union (EU) countries, prior to the implementation of the EU Tobacco Products Directive (TPD), and 2 years post-TPD. …”
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    European adult smokers’ perceptions of the harmfulness of e-cigarettes relative to combustible cigarettes: cohort findings from the 2016 and 2018 EUREST-PLUS ITC Europe Surveys
  11. 5131
    “…Current regulation by the EU water framework directive (European Union, 2000/60/EC) relates to organic pollution by monitoring selected micropollutants; however, aquatic ecosystem responses require a comprehensive understanding of dissolved organic matter (DOM) composition. …”
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    Untargeted characterisation of dissolved organic matter contributions to rivers from anthropogenic point sources using direct‐infusion and high‐performance liquid chromatography/Orbitrap mass spectrometry
  12. 5132
    “…The exact consequences of Brexit on the pharmaceutical supply chain in the United Kingdom will depend on whether a deal is reached and what it entails, but it is likely to be affected by the withdrawal of the United Kingdom from the European Union. Regulatory issues and delays in supply have the potential to negatively affect the ability of UK residents to receive an adequate and timely supply of necessary medicines. …”
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    The Impact of Brexit on the Pharmaceutical Supply Chain of the United Kingdom: Scoping Review Protocol
  13. 5133
    “…This study together with other evidence led to a change in the labels of the IFNB products in September 2019 in the European Union, and IFNB use today may be considered during pregnancy, if clinically needed.…”
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    Pregnancy outcomes after exposure to interferon beta: a register-based cohort study among women with MS in Finland and Sweden
  14. 5134
    “…SIMPLE SUMMARY: The European Union Water Framework Directive has set the objective to develop a good status for water bodies and showed the importance of promoting the sustainable use of water resources in inland anthropic activities, such as freshwater aquaculture, performed in strict accordance with natural waters. …”
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    Improvement of the Water Quality in Rainbow Trout Farming by Means of the Feeding Type and Management over 10 Years (2009–2019)
  15. 5135
    “…Pβ-Cat552 and pβ-Cat675 may be useful biomarkers to predict outcome to chemo-radiation, which targets the DNA repair axis. FUNDING: European Union's Seventh Program for research, technological development and demonstration (agreement N°304,810), the Fondation ARC pour la recherche contre le cancer.…”
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    Genetic markers and phosphoprotein forms of beta-catenin pβ-Cat552 and pβ-Cat675 are prognostic biomarkers of cervical cancer
  16. 5136
    “…Multi-disciplinary approaches that make use of eHealth services can build the evidence to influence public policy. The European Union-funded project EVOTION developed a platform that is fed with real-time data from hearing aids, a smartphone, and additional clinical data and makes public health policy recommendations based on hypothetical public health policy-making models, a big data engine and decision support system. …”
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    Public health policy-making for hearing loss: stakeholders’ evaluation of a novel eHealth tool
  17. 5137
    “…Besides direct cost reduction, lower antimicrobial use and improved animal welfare are crucial in the directive of European Union legislation and are at the forefront of customer choices. …”
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    Impact of Rotten Eggs on Hatchery Performances: A Multicentric Study
  18. 5138
    “…SIMPLE SUMMARY: Broiler farms are authorized to house animals at different stocking densities (kg live weight/m(2)) provided that ammonia, carbon dioxide, temperature, and humidity levels are kept under specific limits set by European Union legislation. The role of stocking density on poultry health and welfare, and consequently on antimicrobial use, is still under debate. …”
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    Antimicrobial Use in Broilers Reared at Different Stocking Densities: A Retrospective Study
  19. 5139
    “…In September 2019, four social scientists from the Animal Research Nexus program gathered together a group of 13 experts to discuss nonlaboratory research under the Animals (Scientific Procedures) Act (A(SP)A) of 1986 (mirroring European Union (EU) Directive 2010/63/EU), which is the primary mechanism for regulating animal research in the UK. …”
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    Animal Research beyond the Laboratory: Report from a Workshop on Places Other than Licensed Establishments (POLEs) in the UK
  20. 5140
    “…US/Canadian products are sold with 5%, 3% and 1.5% (Canada only) nicotine content, whereas European Union (EU) regulation limits nicotine content to 1.7%. …”
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    Differences in flavourant levels and synthetic coolant use between USA, EU and Canadian Juul products
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