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  1. 5761
    “…TRIAL REGISTRATION: This trial was registered with the European Union Clinical Trials Register (https://www.clinicaltrialsregister.eu/), registration number: 2010-019933-89.…”
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    Validation of a continuous infusion of low dose Iohexol to measure glomerular filtration rate: randomised clinical trial
  2. 5762
    “…DISCUSSION: The BeneMin trial can inform as to whether in minocycline we have found a new and effective therapy against negative symptoms of psychosis. The European Union Clinical Trial Register: EudraCT 2010-022463-35 with the registration finalised in July 2011. …”
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    The benefit of minocycline on negative symptoms in early-phase psychosis in addition to standard care - extent and mechanism (BeneMin): study protocol for a randomised controlled trial
  3. 5763
    “…TRIAL REGISTRATION: The CHARISMA is registered at European Union Clinical Trials Register (EudraCT), number: 2013-004952-39, and in the “Netherlands national Trial Register (NTR), number: 4893.…”
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    Neo-adjuvant chemotherapy followed by surgery versus surgery alone in high-risk patients with resectable colorectal liver metastases: the CHARISMA randomized multicenter clinical trial
  4. 5764
    “…BACKGROUND: Migrant populations from countries with generalised HIV epidemics make up a significant proportion of all HIV/AIDS cases in many European Union and European Economic Area (EU/EEA) countries, with heterosexual transmission the predominant mode of HIV acquisition. …”
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    A systematic review of post-migration acquisition of HIV among migrants from countries with generalised HIV epidemics living in Europe: mplications for effectively managing HIV prevention programmes and policy
  5. 5765
    “…Interestingly, all the GT1a sequences encoding M28V in NS5A were from the United States, while GT1b sequences encoding C316N and S556G in NS5B were predominant in the European Union. Variants preexisting at baseline had no significant impact on treatment outcome. …”
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    Resistance Analysis of Baseline and Treatment-Emergent Variants in Hepatitis C Virus Genotype 1 in the AVIATOR Study with Paritaprevir-Ritonavir, Ombitasvir, and Dasabuvir
  6. 5766
    “…This is also one of the proof of concept ambitions of SEURAT-1, the largest ever European Union research initiative on alternative testing, co-funded by the European Commission and Cosmetics Europe. …”
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    Chemical Safety Assessment Using Read-Across: Assessing the Use of Novel Testing Methods to Strengthen the Evidence Base for Decision Making
  7. 5767
    “…DISCUSSION: This study is part of the large, translational project TACTICS (http://www.tactics-project.eu/) that is funded by the European Union and investigates the neural, genetic and molecular factors involved in the pathogenesis of compulsivity. …”
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    Glutamatergic medication in the treatment of obsessive compulsive disorder (OCD) and autism spectrum disorder (ASD) – study protocol for a randomised controlled trial
  8. 5768
    “…OBJECTIVES: We assessed the ability of pesticides that are commonly used in the European Union to suppress prostaglandin D2 (PGD2) synthesis. …”
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    Effects of Common Pesticides on Prostaglandin D2 (PGD2) Inhibition in SC5 Mouse Sertoli Cells, Evidence of Binding at the COX-2 Active Site, and Implications for Endocrine Disruption
  9. 5769
    “…The aim of this study is to implement a consistent methodological approach using the Carbon Budget Model (CBM) to estimate the net CO(2) emissions from FM in 26 European Union (EU) countries for the period 2000–2012, including the impacts of natural disturbances. …”
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    Modelling forest carbon stock changes as affected by harvest and natural disturbances. I. Comparison with countries’ estimates for forest management
  10. 5770
    “…BACKGROUND: The annual burden of disease caused indoor air pollution, including polluted outdoor air used to ventilate indoor spaces, is estimated to correspond to a loss of over 2 million healthy life years in the European Union (EU). Based on measurements of the European Environment Agency (EEA), approximately 90 % of EU citizens live in areas where the World Health Organization (WHO) guidelines for air quality of particulate matter sized < 2.5 mm (PM(2.5)) are not met. …”
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    Reducing burden of disease from residential indoor air exposures in Europe (HEALTHVENT project)
  11. 5771
    “…BACKGROUND: Influencing the life-style risk-factors alcohol, body mass index (BMI), and smoking is an European Union (EU) wide objective of public health policy. …”
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    Potential health gains and health losses in eleven EU countries attainable through feasible prevalences of the life-style related risk factors alcohol, BMI, and smoking: a quantitative health impact assessment
  12. 5772
    “…Priority (www.prionpriority.eu) was a European Union (EU) Framework Program 7 (FP7)-funded project through which 21 European research institutions and small and medium enterprises (SMEs) joined efforts between 2009 and 2014, to conduct coordinated basic and applied research on prions and prion diseases. …”
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    The Priority position paper: Protecting Europe's food chain from prions
  13. 5773
    “…Trial registration Registered to the European Union electronic register of post-authorisation studies (EU PAS register no EUPAS3626).…”
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    Pioglitazone use and risk of bladder cancer in patients with type 2 diabetes: retrospective cohort study using datasets from four European countries
  14. 5774
    “…The main aim of this work is to evaluate the potential impact of implementing current air quality standards for fine particulate matter (PM(2.5)) in the European Union (EU), United States (US) and other countries where PM(2.5) levels are high. …”
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    Implementing the US air quality standard for PM(2.5) worldwide can prevent millions of premature deaths per year
  15. 5775
    “…This study is funded by the European Union’s Seventh Framework Programme. METHODS/DESIGN: EMBalance is a proof-of-concept study designed as a non-commercial, international, multi-centre, single-blind, parallel-group randomised controlled trial to be carried out at four clinical sites in the United Kingdom, Germany, Greece and Belgium. …”
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    EMBalance - validation of a decision support system in the early diagnostic evaluation and management plan formulation of balance disorders in primary care: study protocol of a feasibility randomised controlled trial
  16. 5776
    “…BACKGROUND: The European Union considers diseases to be rare when they affect less than 5 in 10,000 people. …”
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    Adopting Quality Criteria for Websites Providing Medical Information About Rare Diseases
  17. 5777
    “…TRIAL REGISTRATION: European Union Clinical Trials Register 2015-003987-35. …”
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    Metamizole versus ibuprofen at home after day surgery: study protocol for a randomised controlled trial
  18. 5778
    “…A minimum of 290 patients will be enrolled at ∼50 sites in the European Union and North America. The study involves 2 parts. …”
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    Study protocol for a multicentre randomised controlled trial: Safety, Tolerability, efficacy and quality of life Of a human recombinant alkaline Phosphatase in patients with sepsis-associated Acute Kidney Injury (STOP-AKI)
  19. 5779
    “…Recent Control Banding (CB) tools use the classifications of the United Nations Global Harmonized System (UN GHS) or the European Union Classifications, Labelling and Packaging (EU CLP) which are grouped over 5 HBs. …”
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    On the Strength and Validity of Hazard Banding
  20. 5780
    “…The multivariable logistic regression model identified the following determinants with a robust, statistically significant association with publication: phase 2 (60% published; adjusted OR 2.6, 95% CI 1.1–5.9), phase 3 (73% published; adjusted OR 4.1, 95% CI 1.7–10.0), and trials not belonging to phase 1–4 (60% published; adjusted OR 3.2, 95% CI 1.5 to 6.5) compared to phase 1 trials (35% published); trials with a company or investigator as applicant (63% published) compared to trials with a Contract Research Organization (CRO) as applicant (50% published; adjusted OR 1.7; 95% CI 1.1–2.8); and multicenter trials also conducted in other EU countries (68% published; adjusted OR 2.2, 95% CI 1.1–4.4) or also outside the European Union (72% published; adjusted OR 2.0, 95% CI 1.0–4.0) compared to single-center trials (45% published). …”
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    Non-Publication Is Common among Phase 1, Single-Center, Not Prospectively Registered, or Early Terminated Clinical Drug Trials
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