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115501“…Coupled with other studies, our results suggest the importance of long-term monitoring of mental health among young populations exposed to catastrophic events or mass trauma.…”
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115502“…The aim of the present study was to investigate the effects of UA on intestinal health and gut microflora antibiotic-resistance in antibiotic-exposed mice. Kunming mice (n = 80) were randomly allocated into three groups and fed with one of the following diets, respectively: Cont group (n = 20), the basal diet; UA group (n = 20), the basal diet supplemented with 150 mg/kg UA; Tet group (n = 40), the basal diet supplemented with 659 mg/kg chlortetracycline. …”
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115503por Nouatin, Odilon, Mengue, Juliana Boex, Dejon-Agobé, Jean Claude, Fendel, Rolf, Ibáñez, Javier, Ngoa, Ulysse Ateba, Edoa, Jean Ronald, Adégbité, Bayodé Roméo, Honkpéhédji, Yabo Josiane, Zinsou, Jeannot Fréjus, Hounkpatin, Aurore Bouyoukou, Moutairou, Kabirou, Homoet, Andreas, Esen, Meral, Kreidenweiss, Andrea, Hoffman, Stephen L., Theisen, Michael, Luty, Adrian J. F., Lell, Bertrand, Agnandji, Selidji Todagbe, Mombo-Ngoma, Ghyslain, Ramharter, Michael, Kremsner, Peter, Mordmüller, Benjamin, Adegnika, Ayôla Akim“…METHODOLOGY: In a randomized, double-blind Phase I clinical trial, fifty, healthy, lifelong malaria-exposed adult volunteers received three doses of GMZ2 adjuvanted with either Cationic Adjuvant Formulation (CAF) 01 or Alhydrogel, or a control vaccine (Rabies) on days (D) 0, D28 and D56, followed by direct venous inoculation (DVI) of 3,200 P. falciparum sporozoites (PfSPZ Challenge) approximately 13 weeks after last vaccination to assess vaccine efficacy. …”
Publicado 2021
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115504por Akyala, Adamu Ishaku, Awayimbo, Jaggu Ruth, Ogo, Anowai Clementina, Chima, Ndubuisi John, Billyrose, Olusoji Mathew Adeyemi, Engom, Alaba Ovye Godiya“…While molecular techniques remain the gold standard for diagnosis of acute SARS-CoV-2 infection, serological tests have the unique potential to ascertain how much of the population has been exposed to the COVID-19 pathogen. There have been limited published studies to date documenting the performance of SARS-CoV-2 antibody assays in Nigeria and so we evaluated the diagnostic performance of five (5) immunoassay on a set of clinical samples. …”
Publicado 2021
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115505por Hutchins, Kate P., Borg, David N., Bach, Aaron J. E., Bon, Joshua J., Minett, Geoffrey M., Stewart, Ian B.“…BACKGROUND: Despite an increasing rate of women participating in professional sports, emergency services, and military settings where they are exposed to exertional heat stress, our understanding of female thermoregulation and the detrimental effects of heat on women’s performance, especially regarding the menstrual cycle, is limited. …”
Publicado 2021
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115506por Audino, Tania, Grattarola, Carla, Centelleghe, Cinzia, Peletto, Simone, Giorda, Federica, Florio, Caterina Lucia, Caramelli, Maria, Bozzetta, Elena, Mazzariol, Sandro, Di Guardo, Giovanni, Lauriano, Giancarlo, Casalone, Cristina“…Furthermore, to evaluate if and how Italian wastewater management and coastal exposition to extreme weather events may led to susceptible marine mammal populations being exposed to SARS-CoV-2, geomapping data were carried out and overlapped. …”
Publicado 2021
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115507por Zegeye, Betregiorgis, Keetile, Mpho, Ahinkorah, Bright Opoku, Ameyaw, Edward Kwabena, Seidu, Abdul-Aziz, Yaya, Sanni“…We found higher odds of utilization of deworming medication among older pregnant married women (aOR=1.93, 95% CI 1.32–2.84), women with educated husbands (aOR=1.40, 95% CI 1.11–1.77), wealthier women (aOR=3.12, 95% CI 1.95–4.99), women exposed to media (aOR=1.46, 95% CI 1.18–1.80), and those who had four or more antenatal care visits (aOR=1.51, 95% CI 1.24–1.83). …”
Publicado 2021
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115508por Witkowski, Marco, Friebel, Julian, Tabaraie, Termeh, Grabitz, Sinah, Dörner, Andrea, Taghipour, Lena, Jakobs, Kai, Stratmann, Bernd, Tschoepe, Diethelm, Landmesser, Ulf, Rauch, Ursula“…In vitro, human monocytic cells (THP-1) were exposed to metformin and TF expression measured in the presence and absence of the AMP-activated protein kinase (AMPK) activator 5-aminoimidazole-4-carboxamide riboside (AICAR) or the AMPK inhibitor compound C. …”
Publicado 2020
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115509por Rubio, Adonis A., Filsinger Interrante, Maria V., Bell, Benjamin N., Brown, Clayton L., Bruun, Theodora U. J., LaBranche, Celia C., Montefiori, David C., Kim, Peter S.“…The N-heptad repeat (NHR) is a highly conserved region of gp41 exposed in the PHI; it is the target of the FDA-approved drug enfuvirtide and of neutralizing monoclonal antibodies (mAbs). …”
Publicado 2021
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115510“…RESULTS: Nearly 30% and 24.6% of fetuses had been exposed to unfavorable outcome among those delivered following cesarean and vaginal delivery, respectively. …”
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115511“…After both the batches finished their rotation, they were given the survey questionnaire to assess their perception of the model of CBUG Curriculum that they were exposed to. RESULTS: The results of the survey revealed that about 80% of the students in both groups preferred that theory classes and practical training should be conducted in parallel in 6(th) term. …”
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115512por Nelson, Tracy L., Fosdick, Bailey K., Biela, Laurie M., Schoenberg, Hayden, Mast, Sarah, McGinnis, Emma, Young, Michael C., Lynn, Lori, Fahrner, Scott, Nolt, Laura, Dihle, Tina, Quicke, Kendra, Gallichotte, Emily N., Fitzmeyer, Emily, Ebel, Greg D., Pabilonia, Kristy, Ehrhart, Nicole, VandeWoude, Sue“…The frequency of protective behavior practices and essential workers’ concerns regarding contracting COVID-19 and exposing others were measured based on survey responses. …”
Publicado 2021
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115513por Villanueva-Saz, Sergio, Giner, Jacobo, Fernández, Antonio, Lacasta, Delia, Ortín, Aurora, Ramos, Juan José, Ferrer, Luis Miguel, Ruiz de Arcaute, Marta, Tobajas, Ana Pilar, Pérez, María Dolores, Verde, Maite, Marteles, Diana, Hurtado-Guerrero, Ramón, Pardo, Julián, Santiago, Llipsy, González-Ramírez, Andrés Manuel, Macías-León, Javier, García-García, Ana, Taleb, Víctor, Lira-Navarrete, Erandi, Paño-Pardo, José Ramón, Ruíz, Héctor“…Among domestic animals, there have been limited studies regarding the transmissibility and exposure to the infection in natural conditions. Some animals are exposed and/or susceptible to SARS-CoV-2 infection, such as cats, ferrets and dogs. …”
Publicado 2021
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115514por Gagliardi, Mara, Monzani, Romina, Clemente, Nausicaa, Fusaro, Luca, Saverio, Valentina, Grieco, Giovanna, Pańczyszyn, Elżbieta, Yissachar, Nissan, Boccafoschi, Francesca, Corazzari, Marco“…Here we propose an organ ex vivo culture (Gut-Ex-Vivo system, GEVS) based on colon from Balb/c mice cultivated in a dynamic condition, able to model the biochemical and morphological features of the mouse models exposed to DNBS (5–12 days), in 5 h. Indeed, upon DNBS exposure, we observed a dose-dependent: (i) up-regulation of the stress-related protein transglutaminase 2 (TG2); (ii) increased intestinal permeability associated with deregulated tight junction protein expression; (iii) increased expression of pro-inflammatory cytokines, such as TNFα, IFNγ, IL1β, IL6, IL17A, and IL15; (iv) down-regulation of the anti-inflammatory IL10; and (v) induction of Endoplasmic Reticulum stress (ER stress), all markers of IBD. …”
Publicado 2021
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115515por Crooks, Chelsea M., Weiler, Andrea M., Rybarczyk, Sierra L., Bliss, Mason, Jaeger, Anna S., Murphy, Megan E., Simmons, Heather A., Mejia, Andres, Fritsch, Michael K., Hayes, Jennifer M., Eickhoff, Jens C., Mitzey, Ann M., Razo, Elaina, Braun, Katarina M., Brown, Elizabeth A., Yamamoto, Keisuke, Shepherd, Phoenix M., Possell, Amber, Weaver, Kara, Antony, Kathleen M., Morgan, Terry K., Zeng, Xiankun, Dudley, Dawn M., Peterson, Eric, Schultz-Darken, Nancy, O’Connor, David H., Mohr, Emma L., Golos, Thaddeus G., Aliota, Matthew T., Friedrich, Thomas C.“…However, a significantly higher burden of ZIKV viral RNA (vRNA) was found in the maternal-fetal interface tissues of the macaques exposed to an African-lineage isolate. Our findings suggest that ZIKV of any genetic lineage poses a threat to pregnant individuals and their infants. …”
Publicado 2021
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115516por Xu, Yingying, Su, Sizhen, Jiang, Zhendong, Guo, Suihuai, Lu, Qingdong, Liu, Lin, Zhao, Yimiao, Wu, Ping, Que, Jianyu, Shi, Le, Deng, Jiahui, Meng, Shiqiu, Yan, Wei, Sun, Yankun, Yuan, Kai, Lin, Xiao, Sun, Siwei, Ravindran, Arun V., Chen, Sijing, Wing, Yun Kwok, Tang, Xiangdong, Ran, Maosheng, Lu, Yu, Shi, Jie, Huang, Guofu, Bao, Yanping, Lu, Lin“…Background: University students who are exposed to coronavirus disease 2019 (COVID-19) could be mentally distressed. …”
Publicado 2021
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115517por Zuberi, Alina, Waqas, Ahmed, Naveed, Sadiq, Hossain, Md Mahbub, Rahman, Atif, Saeed, Khalid, Fuhr, Daniela C.“…Pooled analyses of current, period and lifetime prevalence showed the highest prevalence for depression (14.8%, 95% confidence interval, CI: 10.7–20.1%), followed by generalized anxiety disorder (GAD) (10.4%, 95% CI: 7.1–14.7%), post-traumatic stress disorder (7.2%, 95% CI: 2.9–16.6%), substance use (4.0%, 95% CI: 3.1–5.2%), obsessive compulsive disorder (2.8%, 95% CI: 1.6–4.9%), phobic disorders (1.8%, 95% CI: 1.1–2.8%), panic disorders (1.1%, 95% CI: 0.6–2.2%), bipolar disorders (0.7%, 95% CI: 0.3–1.6%), and psychosis (0.5%, 95% CI: 0.3–0.9%). Populations exposed to adverse events had higher prevalence of mental disorders than the general population. …”
Publicado 2021
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115518“…Notably, six hub genes (STAT1, IFIT3, RSAD2, ISG15, IFI44, IFI6) were down-regulated in cells exposed to both metformin and Mycobacterium tuberculosis antigens. …”
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115519por Fu, Zhonghua, Jiang, Zhengying, Guo, Guanghua, Liao, Xincheng, Liu, Mingzhuo, Xiong, Zhenfang“…Both of the human alveolar epithelial cell (HPAEpiC) and primary rat alveolar epithelial cell were exposed to lipopolysaccharide (LPS) for making in-vitro alveolar epithelial cell injury model. …”
Publicado 2021
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115520“…Heart dosimetry was represented by V(D) indices, which is a percentage of volume exposed to dose D or greater. Multivariate Cox models with patient specific covariates and single V(D) index per model was used to find a range of doses which were predictive for OS. …”
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