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115521por Zhang, Ning, Liu, Ying, Han, Dongmei, Guo, Xin, Mao, Zhuang, Yang, Wei, Cheng, Guanghui“…We report the 90% of the target volume receiving the minimum dose for high risk clinical target volume (HR-CTV D(90)) and intermediate risk clinical target volume (IR-CTV D(90)), and the minimum doses to the most exposed 0.1, 1, and 2 cm³ [Formula: see text] doses at the International Commission on Radiation Units and Measurements (D(ICRU)) for organs at risk (OARs). …”
Publicado 2021
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115522por Lambuk, Lidawani, Iezhitsa, Igor, Agarwal, Renu, Agarwal, Puneet, Peresypkina, Anna, Pobeda, Anna, Ismail, Nafeeza Mohd“…Electroretinography indicated that pre-treatment with MgAT partially preserved the functional activity of NMDA-exposed retinas. MgAT abolished NMDA-induced increase of retinal phospho-NF-κB, phospho-p53 and AP-1 expression and suppressed NMDA-induced transcriptional activity of NF-κB, p53 and AP-1 family members (c-Jun/c-Fos). …”
Publicado 2021
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115523por Williams, Laura, Jurado, Silvia, Llorente, Francisco, Romualdo, Alberto, González, Sara, Saconne, Ana, Bronchalo, Isabel, Martínez-Cortes, Mercedes, Pérez-Gómez, Beatriz, Ponz, Fernando, Jiménez-Clavero, Miguel Ángel, Lunello, Pablo“…To validate the ELISA, a panel of 416 sera from exposed personnel at essential services in Madrid City Council were tested, and the results compared to those obtained by another ELISA, already validated, used as reference. …”
Publicado 2021
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115524por Chen, Junyu, Liu, Jian, Wu, Shan, Liu, Wei, Xia, Yang, Zhao, Jing, Yang, Yanrong, Wang, Yuan, Peng, Yuanqing, Zhao, Shuhua“…Moreover, there was no significant change in the expression levels of Stat3 and p-Stat3 in MC3T3-E1 cells exposed to ATZ. This phenomenon was observed while the proliferation rate was enhanced in MC3T3-E1 cells by ATZ. …”
Publicado 2021
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115525por Diaz-Escobar, Julia, Ordóñez-Guillén, Nelson E., Villarreal-Reyes, Salvador, Galaviz-Mosqueda, Alejandro, Kober, Vitaly, Rivera-Rodriguez, Raúl, Lozano Rizk, Jose E.“…BACKGROUND: The COVID-19 pandemic has exposed the vulnerability of healthcare services worldwide, especially in underdeveloped countries. …”
Publicado 2021
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115526por Yang, Zhen, Li, Zhuman, Guo, Zhijun, Ren, Yu, Zhou, Ting, Xiao, Zhijun, Duan, Jingjing, Han, Chuangchuang, Cheng, Yuanchi, Xu, Feng“…The expression of kynurenine pathway related genes TDO, IDO1, IDO2, and apoptosis-related genes caspase1, 3, 4, 5, 7, 12 in tumor tissues were measured by western blotting and qRT-PCR. A549 cells were exposed with FLX (15 μmol/L) and its effect on cell proliferation, migration, and clonal formation were detected. …”
Publicado 2021
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115527por Gong, Siqi, Lakhashe, Samir K., Hariraju, Dinesh, Scinto, Hanna, Lanzavecchia, Antonio, Cameroni, Elisabetta, Corti, Davide, Ratcliffe, Sarah J., Rogers, Kenneth A., Xiao, Peng, Fontenot, Jane, Villinger, François, Ruprecht, Ruth M.“…In a pilot study, for which we re-used animals previously exposed to SHIV but completely protected from viremia by different classes of anti-HIV neutralizing monoclonal antibodies (mAbs), we made a surprise finding: low-dose intravenous (i.v.) …”
Publicado 2021
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115528“…(a) In the metal–alkyl approach, a free-base corrole is exposed to an alkyllithium and the resulting lithio-corrole is treated with an early transition metal chloride; a variant of the method eschews alkyllithium and deploys a transition metal–alkyl instead, resulting in elimination of the alkyl group as an alkane and insertion of the metal into the corrole. …”
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115529“…Further studies are needed to investigate the impact of BLL on patients with malaria to help the clinician determine the risk of severity, such as the development of neurological features or severe anemia, among patients exposed to lead.…”
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115530por Sun, Yi, Leng, Ping, Guo, Pengcheng, Gao, Huanshen, Liu, Yikai, Li, Chenkai, Li, Zhenghui, Zhang, Haining“…The expression of GPER in cartilage tissue taken from the clinical patients was detected by RT-PCR and Western blot as well as immunohistochemistry, and the correlation between GPER expression and OA was also investigated. The chondrocytes exposed to mechanical stress were treated with estrogen, G-1, G15, GPER-siRNA and YAP (Yes-associated protein)-siRNA. …”
Publicado 2021
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115531por Hua, Rong, Zou, Jilong, Ma, Ying, Wang, Xiaomei, Chen, Yao, Li, Yuan, Du, Jianyang“…BMSCs were treated with caffeine and further exposed to different concentrations of psoralidin (PL) (0.01, 0.1, 1, and 10 µM) for 48 h. …”
Publicado 2021
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115532por Lapierre, Nolwenn, Um Din, Nathavy, Igout, Manuella, Chevrier, Joël, Belmin, Joël“…However, the methods of delivery will be different; one group will be exposed to the Medimoov exergame platform, and the other only to traditional means of psychomotor rehabilitation. …”
Publicado 2021
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115533por Noriega, Alejandro, Meizner, Daniela, Camacho, Dalia, Enciso, Jennifer, Quiroz-Mercado, Hugo, Morales-Canton, Virgilio, Almaatouq, Abdullah, Pentland, Alex“…Additionally, the results suggest that the ARIA system can be useful as an assistive tool, as sensitivity was significantly higher in the experimental condition where ophthalmologists were exposed to the ARIA system’s answer prior to their own classification (93.3%), compared with the sensitivity of the condition where participants assessed the images independently (87.3%; P=.05). …”
Publicado 2021
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115534“…Significant majorities were “very concerned” about exposing themselves (75%), family members (86%), and patients (80%) to COVID‐19 given the nature of their work. …”
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115535por Misra, Namita, Clavaud, Cécile, Guinot, Florent, Bourokba, Nasrine, Nouveau, Stephanie, Mezzache, Sakina, Palazzi, Paul, Appenzeller, Brice M. R., Tenenhaus, Arthur, Leung, Marcus H. Y., Lee, Patrick K. H., Bastien, Philippe, Aguilar, Luc, Cavusoglu, Nükhet“…Environmental pollution is composed of several factors, namely particulate matter (PM(2.5), PM(10)), ozone and Ultra Violet (UV) rays among others and first and the most exposed tissue to these substances is the skin epidermis. …”
Publicado 2021
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115536por Nuertey, Benjamin Demah, Ekremet, Kwame, Haidallah, Abdul-Rashid, Mumuni, Kareem, Addai, Joyce, Attibu, Rosemary Ivy E., Damah, Michael C., Duorinaa, Elvis, Seidu, Anwar Sadat, Adongo, Victor C., Adatsi, Richard Kujo, Suri, Hisyovi Caedenas, Komei, Abass Abdul-Karim, Abubakari, Braimah Baba, Weyori, Enoch, Allegye-Cudjoe, Emmanuel, Sylverken, Augustina, Owusu, Michael, Phillips, Richard O.“…Most countries are practicing partial or total lockdown, vaccination, massive education on hygiene, social distancing, isolation of cases, quarantine of exposed and various screening approaches such as temperature and symptom-based screening to break the transmission. …”
Publicado 2021
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115537por Sun, Ying, Chen, Beibei, Li, Jisheng, Peng, Ling, Li, Shuguang, Yu, Xuejun, Li, Li“…Fifty-nine (92.2%) patients had been previously treated with trastuzumab and/or T-DM1, while 11 (17.2%) patients had been exposed to lapatinib. The objective response rate (ORR) of all patients was 73.4%, and the disease control rate (DCR) was 98.4%, with a clinical benefit rate (CBR) of 87.5%. …”
Publicado 2021
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115538por Kou, Samuel, Kile, Sammi, Kambampati, Sai Samhith, Brady, Evelyn C., Wallace, Hayley, De Sousa, Carlos M., Cheung, Kin, Dickey, Lauren, Wentworth, Kelly L., Hsiao, Edward“…We also identified patients with FOP who were exposed to or contracted the SARS-CoV-2 virus, or who received a COVID-19 vaccine, to investigate if patients with FOP were at increased risks of complications from SARS-CoV2 exposure. …”
Publicado 2021
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115539por Wu, Yuehuan, Fu, Cong, Li, Bing, Liu, Chang, He, Zhi, Li, Xing-Er, Wang, Ailing, Ma, Genshan, Yao, Yuyu“…Furthermore, BK treatment of HG-exposed cells led to elevated P-Ser(473)AKT and eNOS protein expression compared with HG treatment alone. …”
Publicado 2021
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115540por Dzhambov, Angel M., Lercher, Peter, Browning, Matthew H.E.M., Stoyanov, Drozdstoy, Petrova, Nadezhda, Novakov, Stoyan, Dimitrova, Donka D.“…CONCLUSIONS: Students who spent most of their time at home during the COVID-19 epidemic experienced better mental health when exposed to more greenery. Our findings support the idea that exposure to greenery may be a valuable resource during social isolation in the home. …”
Publicado 2021
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