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116401por Kirenga, Bruce J., de Jong, Corina, Katagira, Winceslaus, Kasozi, Samuel, Mugenyi, Levicatus, Boezen, Marike, van der Molen, Thys, Kamya, Moses R.“…Significantly more people with asthma smoked than non-asthmatics: 14.2% vs. 6.3%, p < 0.001, were exposed to biomass smoke: 28.0% vs. 20.0%, p < 0.001, had family history of asthma: 26.9% vs. 9.4%, p, < 0.001, had history of TB: 3.1% vs. 1.30%, p = 0.01, and had hypertension: 17.9% vs. 12.0%, p = 0. 003. …”
Publicado 2019
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116402por Chen, Huang‐Jen, Wang, Ching‐Chia, Chan, Ding‐Cheng, Chiu, Chen‐Yuan, Yang, Rong‐Sen, Liu, Shing‐Hwa“…METHODS: C2C12 myoblasts were used to assess the effects of low‐dose acrolein (0.125–1 μM) on myogenesis in vitro. Mice were exposed daily to acrolein in distilled water by oral administration (2.5 and 5 mg/kg) for 4 weeks with or without glycerol‐induced muscle injury to investigate the effects of acrolein on muscle wasting and regeneration. …”
Publicado 2018
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116403por Cardenas, Andres, Faleschini, Sabrina, Cortes Hidalgo, Andrea, Rifas-Shiman, Sheryl L., Baccarelli, Andrea A., DeMeo, Dawn L., Litonjua, Augusto A., Neumann, Alexander, Felix, Janine F., Jaddoe, Vincent W. V., El Marroun, Hanan, Tiemeier, Henning, Oken, Emily, Hivert, Marie-France, Burris, Heather H.“…RESULTS: In Project Viva, 2.9% (14/479) pregnant women were prescribed antidepressants, 9.0% (40/445) experienced high pregnancy-related anxiety, and 8.2% (33/402) reported symptoms consistent with depression. Newborns exposed to antidepressants in pregnancy had 7.2% lower DNA methylation (95% CI, − 10.4, − 4.1; P = 1.03 × 10(−8)) at cg22159528 located in the gene body of ZNF575, and this association replicated in the Generation R Study (β = − 2.5%; 95% CI − 4.2, − 0.7; P = 0.006). …”
Publicado 2019
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116404por Guo, Gui-Fang, Wang, Yi-Xing, Zhang, Yi-Jun, Chen, Xiu-Xing, Lu, Jia-Bin, Wang, Hao-Hua, Jiang, Chang, Qiu, Hui-Quan, Xia, Liang-Ping“…RESULTS: In CACO-2 cells exposed to cetuximab, LC3 and 4E-BP1 were upregulated, and P62 was downregulated. …”
Publicado 2019
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116405por Jia, Tie-Wu, Wang, Wei, Sun, Le-Ping, Lv, Shan, Yang, Kun, Zhang, Neng-Min, Huang, Xi-Bao, Liu, Jian-Bing, Liu, Han-Cheng, Liu, Rui-Hua, Gawish, Fathia A., Habib, Mohamed R., El-Emam, Mohamed A., King, Charles H., Zhou, Xiao-Nong“…METHODS: In the laboratory, Oncomelania hupensis, Biomphalaria alexandrina and Bulinus truncatus were exposed to 4% TDS, and the median lethal concentration (LC(50)) was estimated at 24, 48 and 72 h. …”
Publicado 2019
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116406“…However, this single-compound approach neglects the fact that the mixture exposed to human may act additively or synergistically to induce greater toxicity than the single compounds exposure due to their similarities in the mode of action and targets. …”
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116407“…The cytokines IL-6, IL-8 and vascular endothelial growth factor (VEGF) secreted from ARPE-19 cells exposed to pro-oxidants were estimated by ELISA. In vitro angiogenesis assay was performed with conditioned media of the pro-oxidant treated ARPE-19 cells in Geltrex-Matrigel coated 96-well plate. …”
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116408por Harasemiw, Oksana, Drummond, Neil, Singer, Alexander, Bello, Aminu, Komenda, Paul, Rigatto, Claudio, Lerner, Jordyn, Sparkes, Dwight, Ferguson, Thomas W., Tangri, Navdeep“…Control clinics will only be exposed to current guidelines for CKD management, without active dissemination. …”
Publicado 2019
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116409por Kundu, Nabanita, Domingues, Cleyton, Kokkinos, Peter, Nylen, Eric, Sen, Sabyasachi“…Methods: In vitro, commercially obtained human fat-derived stromal cells were exposed to adipogenic media and endothelial conditioned media (obtained from mature endothelial cells, HUVECs, 40 fold concentrated) was added. …”
Publicado 2019
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116410por Bertozzi, Beatrice, Backhaus, Jenny, Iwen, Alexander, Rademacher, Leonie, Chamorro, Rodrigo, Wilms, Britta, Lehnert, Hendrik, Schmid, Sebastian“…Using a water-perfused suit, subjects were exposed to thermoneutrality (25°C) and to moderate cold (16.07°C, shivering excluded) according to a protocol validated for BAT activation. …”
Publicado 2019
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116411“…Additional genetic evaluation was undertaken prior to exposing the patient to the risk of surgery. The patient was found to have a rare cause of FHH, a heterozygous c.43C>T, Arg15Cys missense mutation in AP2S1 (rs.39751448). …”
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116412por Jaimes-Hoy, Lorraine, Parra-Montes de Oca, Marco, Romero, Fidelia, Charli, Jean-Louis, Joseph-Bravo, Patricia“…At adulthood (PND 63), Gh and Iso rats had access to chow or a palatable diet (Pd: peanuts, cookies, chow) for 1 or 3 months and exposed, in the latter, to 1 h of restraint stress (RES). …”
Publicado 2019
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116413por Metzger, Peter, Carlson, Bradley, Sun, Hui, Cui, Zhenzhong, Gavrilova, Oksana, Chen, Min, Weinstein, Lee“…MC4RF51L mice had normal body temperature at room temperature (22(o)C) and maintained their temperature when exposed to 6(o)C for 5 hours, consistent with an intact thermogenic response to acute cold conditions. …”
Publicado 2019
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116414por Landes, Megan, van Lettow, Monique, Nkhoma, Ernest, Tippett Barr, Beth, Truwah, Zinenani, Shouten, Erik, Jahn, Andreas, Auld, Andrew, Kalua, Thokozani, van Oosterhout, Joep J“…METHODS: HIV‐positive mothers at four to twenty‐six weeks postpartum were enrolled in a nested cross‐sectional study within the “National Evaluation of Malawi's PMTCT Programme” cohort study between October 2014 and May 2016. HIV‐exposed infants received HIV‐1 DNA testing and venous samples determined maternal VL, classified as unsuppressed (>1000 copies/mL), low‐detectable (40 to 1000 copies/mL) or undetectable (<40 copies/mL). …”
Publicado 2019
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116415por Dang, Zexu, Avolio, Elisa, Albertario, Ambra, Sala-Newby, Graciela B., Thomas, Anita C., Wang, Nianhong, Emanueli, Costanza, Madeddu, Paolo“…In vitro hNGF induced neurite outgrowth and exerted anti-apoptotic actions on rat PC12 cells exposed to high glucose via activation of the canonical neurotrophic tyrosine kinase receptor type 1 (TrkA) signalling pathway. …”
Publicado 2019
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116416por Adamou, Rafiou, Dechavanne, Célia, Sadissou, Ibrahim, d’Almeida, Tania, Bouraima, Aziz, Sonon, Paulin, Amoussa, Roukiyath, Cottrell, Gilles, Le Port, Agnès, Theisen, Michael, Remarque, Edmond J., Longacre, Shirley, Moutairou, Kabirou, Massougbodji, Achille, Luty, Adrian J. F., Nuel, Gregory, Migot-Nabias, Florence, Sanni, Ambaliou, Garcia, André, Milet, Jacqueline, Courtin, David“…Evaluating antibody responses in infants naturally-exposed to malaria will allow to better understand the establishment of anti-malarial immunity and to contribute to a vaccine development by identifying the most appropriate merozoite candidate antigens. …”
Publicado 2019
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116417“…However, dairy cattle managed under grazing conditions are exposed to a different set of risk factors for lameness, mainly associated with cow tracks. …”
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116418por Tallarico, Marco, Ceruso, Francesco Mattia, Muzzi, Leonardo, Meloni, Silvio Mario, Kim, Yong-Jin, Gargari, Marco, Martinolli, Matteo“…Autogenous bone was placed alone over the exposed implant surface, then mixed with inorganic bovine bone material. …”
Publicado 2019
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116419“…The expression of miR-34a was detected by reverse transcription-polymerase chain reaction (commonly known as RT-PCR) before and after transfection. Cells were exposed to 2 μM doxorubicin or phosphate-buffered saline before and after transfection. …”
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116420por Brent, Bernadette, Obonyo, Nchafatso, Akech, Samuel, Shebbe, Mohammed, Mpoya, Ayub, Mturi, Neema, Berkley, James A., Tulloh, Robert M. R., Maitland, Kathryn“…DESIGN, SETTING, AND PARTICIPANTS: A prospective, matched case-control study, the Cardiac Physiology in Malnutrition (CAPMAL) study, of 88 children with SAM (exposed) vs 22 severity-matched patients without SAM (unexposed) was conducted between March 7, 2011, and February 20, 2012; data analysis was performed from October 1, 2012, to March 1, 2016. …”
Publicado 2019
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