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116441por Krempaska, Kristina, Barnowski, Sandra, Gavini, Jacopo, Hobi, Nina, Ebener, Simone, Simillion, Cedric, Stokes, Andrea, Schliep, Ronja, Knudsen, Lars, Geiser, Thomas K., Funke-Chambour, Manuela“…METHODS: Primary normal human lung and IPF-FB were exposed to TGF-β (5 ng/ml), Azithromycin (50 μM) alone or in combination prior to gene expression analysis. …”
Publicado 2020
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116442por Ahmad, Ramala Masood, Cheng, Cheng, Sheng, Jia, Wang, Wei, Ren, Hong, Aslam, Muhammad, Yan, Yuanxin“…In this study, a JA biosynthesis mutant opr7opr8 was used for the investigation of JA roles in the salt stress responses of maize seedlings, whose roots were exposed to 0 to 300 mM NaCl. Foliar stomatal observation showed that opr7opr8 had a larger stomatal aperture than wild type (WT) (B73) under salinity stress, indicating that JA positively regulates guard cell movement under salt stress. …”
Publicado 2019
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116443por Shang, Mengmeng, Sun, Xiao, Guo, Lu, Shi, Dandan, Liang, Ping, Meng, Dong, Zhou, Xiaoying, Liu, Xinxin, Zhao, Yading, Li, Jie“…Then, PC3 cells were exposed to (1) PTX (4 μg/mL), (2) NDs (30 μg/mL), (3) PTX-loaded NDs (34 μg/mL), (4) RT (6 Gy), (5) RT (10 Gy), (6) combination of PTX (4 μg/mL), ultrasound (0.5 W/cm(2), 30 s) and RT (6 Gy), (7) combination of NDs (30 μg/mL), ultrasound (0.5 W/cm(2), 30 s) and RT (6Gy), (8) combination of PTX-loaded NDs (30 μg/mL), ultrasound (0.5 W/cm(2), 30 s) and RT (6 Gy). 24 hrs later, CCK-8 assay, flow cytometry and migration assay were carried out to evaluate their therapeutic effects in CRT. …”
Publicado 2020
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116444por Tan, Chao-Yang, Wang, Yan-Ping, Han, Yuan-Yuan, Lu, Bi-Han, Ji, Wei, Zhu, Li-Cang, Wang, Yang, Shi, Wen-Yan, Shan, Li-Ya, Zhang, Liang, Ma, Ke-Tao, Li, Li, Si, Jun-Qiang“…Rats in the control group received no treatment, and the rat sciatic nerve was only exposed in the sham group. Rats in the chronic constriction injury group were established into chronic constriction injury models by ligating sciatic nerve and rats were given bumetanide, an inhibitor of NKCC1, based on chronic constriction injury modeling in the chronic constriction injury + bumetanide group. …”
Publicado 2019
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116445“…Dual-luciferase reporter assay using HEK-293T cells was performed to show the direct interaction of miR-29b-3p and the 3′UTR of SIRT1. HRMECs were exposed to 5.5 mmol/L of glucose (normal control), 5.5 mmol/L of glucose and 24.5 mmol/L of mannitol (osmotic pressure control), 30 mmol/L of glucose [hyperglycemia (HG)], 150 μmol/L of CoCl(2) (hypoxia), and 30 mmol/L of glucose plus 150 μmol/L of CoCl(2) (HG-CoCl(2)). …”
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116446“…In some countries, replacement gilts are reared with finisher pigs destined for slaughter, so they are exposed to sexual and aggressive behaviors performed by males. …”
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116447“…Long-lived natural radionuclides such as ((238)U) uranium-238, ((232)Th) thorium-232, ((226)Ra) radium-226 and ((40)K) potassium-40 and heavy metals are normally exposed to the surface during mining activities. They enter the human body when inhaled (as dust) or ingested (by drinking contaminated water). …”
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116448por Huang, Yun-Ling, Zeng, Ning-Xi, Chen, Jie, Niu, Jie, Luo, Wu-Long, Liu, Ping, Yan, Can, Wu, Li-Li“…Chronic unpredictable mild stress depression models were established by exposing Sprague-Dawley rats to various mild stressors, including white noise, thermal swimming, stroboscopic illumination, soiled cages, pairing with three other stressed animals, cold swimming, tail pinch, restraint and water and food deprivation. …”
Publicado 2019
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116449por Sterling, Timothy R., Njie, Gibril, Zenner, Dominik, Cohn, David L., Reves, Randall, Ahmed, Amina, Menzies, Dick, Horsburgh, C. Robert, Crane, Charles M., Burgos, Marcos, LoBue, Philip, Winston, Carla A., Belknap, Robert“…These updated guidelines do not apply when evidence is available that the infecting M. tuberculosis strain is resistant to both isoniazid and rifampin; recommendations for treating contacts exposed to multidrug-resistant tuberculosis were published in 2019 (Nahid P, Mase SR Migliori GB, et al. …”
Publicado 2020
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116450por Ossenkoppele, Rik, Lyoo, Chul Hyoung, Jester-Broms, Jonas, Sudre, Carole H., Cho, Hanna, Ryu, Young Hoon, Choi, Jae Yong, Smith, Ruben, Strandberg, Olof, Palmqvist, Sebastian, Kramer, Joel, Boxer, Adam L., Gorno-Tempini, Maria L., Miller, Bruce L., La Joie, Renaud, Rabinovici, Gil D., Hansson, Oskar“…CONCLUSIONS AND RELEVANCE: Results of this study suggest that women and young patients with AD have relative preservation of brain structure when exposed to neocortical pathological tau. Interindividual differences in resilience to pathological tau may be important to disease progression because participants with both low brain and cognitive resilience had the most rapid cognitive decline over time.…”
Publicado 2020
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116451por Hu, Xiaolei, Zhang, Hengyan, Zhuang, Langen, Jin, Guoxi, Yang, Qingqing, Li, Min, Sun, Weihua, Chen, Fengling“…RESULTS: Knockdown of Ufm1 by lentivirus shRNA targeting Ufm1 (Lv-shUfm1) led to decreased secretion of IL-6, IL-1β, ICAM-1, VCAM-1, MCP-1 and CXCL2 in RAW264.7 cells that were exposed to LPS and TNF-α, while lentiviral overexpression of Ufm1 (Lv-Ufm1) caused the opposite effect. …”
Publicado 2020
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116452por Argaw, Mesele Damte, Asfaw, Maeza Mitiku, Ayalew, Mekonen Birhane, Desta, Binyam Fekadu, Mavundla, Thandisizwe Redford, Gidebo, Kassa Daka, Frew, Aynalem Hailemichael, Mitiku, Aychiluhim Damtew, Desale, Alebel Yaregal“…The practice deprives newborns of valuable nutrients and protection of colostrum and exposes them to preventable morbidity and mortality. …”
Publicado 2019
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116453por Arnetz, Bengt B., Sudan, Sukhesh, Arnetz, Judith E., Yamin, Jolin B., Lumley, Mark A., Beck, John S., Stemmer, Paul M., Burghardt, Paul, Counts, Scott E., Jamil, Hikmet“…Civilians in war are exposed to both psychological trauma and environmental hazards, such as metals. …”
Publicado 2020
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116454“…MoS(2) with a two dimensional (2D) layered structure, a narrow bandgap and the ability of getting excited while being exposed to visible light, has demonstrated great potential in visible-light-driven photocatalysts. …”
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116455“… A 1-step RT-PCR assay, targeting a 730 bp fragment of the nucleocapsid (N) gene of bovine coronavirus (BCV), and a nested PCR assay, targeting a 407 bp fragment of the N gene, were developed to detect BCV in nasal swab and fecal samples of calves experimentally exposed to BCV. Both 1-step RT-PCR and nested PCR recognized cell culture passaged isolates of 10 bovine respiratory coronavirus (BRCV), 5 calf diarrhea (CD) and 8 winter dysentery (WD) strains of BCV, but not transmissible gastroenteritis coronavirus or bovine rotavirus. …”
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116456por Okamura, Yo, Morimoto, Natsuki, Ikeda, Daisuke, Mizusawa, Nanami, Watabe, Shugo, Miyanishi, Hiroshi, Saeki, Yuichi, Takeyama, Haruko, Aoki, Takashi, Kinoshita, Masato, Kono, Tomoya, Sakai, Masahiro, Hikima, Jun-ichi“…Furthermore, to reveal the influence of these downregulated genes on the gut microbiome in IL-17A/F1-KO, 16S rRNA-based metagenomic sequencing analysis was conducted to analyze the microbiome constitution. Under a non-exposed state, the intestinal microbiome of IL-17A/F1-KO medaka differed at the phylum level from wild-type, with significantly higher levels of Verrucomicrobia and Planctomycetes. …”
Publicado 2020
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116457“…Previous research has not examined major increases in space allowances, so we investigated sheep responses to a doubling of the standard Australian allowance. Sheep were exposed to simulated ship motion of a regular or irregular nature, representing smooth sailing or high seas, or a control treatment without motion. …”
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116458“…There were 104 (2.12%) healthy counselees, 147 (2.99%) hypochondriacal counselees, 34 (0.69%) exposed counselees, 853 (17.36%) mildly suspicious counselees, 42 (0.85%) moderately suspicious counselees, 3550 (72.26%) highly suspicious counselees, and 183 (3.72%) severely suspicious counselees. …”
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116459“…Under conditions of this study, calves fed variable amount of milk replacer and exposed to immunological challenge before weaning had greater BW gain, but also increased incidence of diarrhea that required added veterinary treatments.…”
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116460por Githinji, Edward K., Irungu, Lucy W., Ndegwa, Paul N., Machani, Maxwell G., Amito, Richard O., Kemei, Brigid J., Murima, Paul N., Ombui, Geoffrey M., Wanjoya, Antony K., Mbogo, Charles M., Mathenge, Evan M.“…METHODS: Mosquito larvae were sampled using a dipper, reared into 3-5-day-old female mosquitoes [4944] which were exposed to 0.75% permethrin and 0.05% deltamethrin using World Health Organization tube assay method. …”
Publicado 2020
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