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  1. 116461
    “…RESULTS: Cohort sizes ranged from 1.3 to 4.1 million, depending on the outcome. The number of women exposed to duloxetine varied by cohort and exposure contrast and was around 2500-3000 for early pregnancy exposure and 900-950 for late pregnancy exposure. …”
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    Maternal and fetal outcomes following exposure to duloxetine in pregnancy: cohort study
  2. 116462
    “…Following artificial insemination (AI), heifers were exposed to five bulls for 71 d. On d 214 and 291, AI and overall pregnancy rates, respectively, were determined. …”
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    Effects of spring administration of extended-release eprinomectin on fescue toxicosis, performance, and reproduction of fall-born beef heifers
  3. 116463
    “…So, we set out to test the hypothesis that exposure to IAA would lead to disrupted expression of key hypothalamic and pituitary genes related to reproductive function. We continually exposed female adult CD1 mice to 0.5, 10, 100, or 500 mg/L IAA in their drinking water for approximately 35 days (postnatal day 40 (P40) to their first day in diestrus following P75.) …”
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    SUN-241 Adult Exposure to Iodoacetic Acid Leads to Abnormal Expression of Key Genes Related to Hypothalamic and Pituitary Control of Reproductive Function
  4. 116464
    “…Background: Autoimmune diabetes mellitus (CPI-DM) caused by immune checkpoint inhibitors (CPIs) is rare- occurring in approximately one percent of patients exposed to this form of cancer immunotherapy. Typically, this immune related adverse event occurs after treatment with PD-1/PD-L1 inhibitors. …”
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    SAT-667 Partial Beta-Cell Destruction: An Atypical Case of Immune Checkpoint Inhibitor Diabetes Mellitus
  5. 116465
    “…BPS can leach into food and drink products, exposing humans to these chemicals. Evidence suggests BPS is also an EDC with similar endocrine disrupting effects. …”
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    SAT-728 The Regulation of Tumor Suppressor Genes P53, BRCA-2, and Cell Cycle Protein p21 by Bisphenol S (BPS) in MCF-7 and T47-D Breast Cancer Cells
  6. 116466
    “…To this end, 3 months-old male C57Bl6J WT or Nrf2 knockout (KO) mice were exposed to 0.05% sodium iodide in their water for 7 days. …”
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    SAT-455 Mouse Thyroid Responds to Iodine Overload by Transcriptionally Enhancing the Keap1/Nrf2 Antioxidant Response and by Upregulating Nrf2-Dependent and Independent Inflammatory and Fibrosis Pathways
  7. 116467
    “…In parallel, pretreated and non-pretreated tissues were exposed to increasing concentrations of oxytocin or PGF(2α) (0.1-10uM). …”
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    OR20-05 Regulation of Mouse Uterine Contractility by Regulator of G-Protein Signalling 2
  8. 116468
    “…Mitotane therapy is frequently associated with new onset hypothyroidism with a prevalence of 73% in our cohort of exposed patients and is most likely of central etiology. 72.7% of cases occur in the first year of treatment while 9.1% occur in the second year. …”
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    SAT-158 New Data on High Prevalence and Time of Occurrence of New Onset Hypothyroidism Associated with Mitotane Therapy in a Cohort of Adrenocortical Cancer
  9. 116469
    por Barnes, Jessica W, Lucera, Erick
    Publicado 2020
    “…The h-Patch™ provides a simple all-in-one delivery device with no exposed needle, no programming or infusion set required, additionally it can be configured to deliver two payload in separate reservoirs offering the potential option of an insulin/GLP-1 infusion combination. …”
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    SAT-635 Results of a Preclinical Pilot Study Evaluating 24-Hour Subcutaneous Infusion of the GLP-1 Analogue Liraglutide Delivered via the H-Patch Wearable Device
  10. 116470
    “…To this end, we generated mice with systemic activation of the Nrf2 pathway (Keap1(flox/–)), as well as mouse models with tissue-specific Nrf2 pathway activation: adipocyte-specific (Fabp4Cre::Keap1(flox/ flox)) and myeloid cell-specific (LymCre::Keap1(flox/ flox)). These mice were exposed to a high-fat diet (HFD) 60% kcal fat regimen for 6-weeks or crossed into the db/db background. …”
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    SUN-LB101 NRF2 Represses Obesity-Associated Adipose Tissue Inflammation in Mice
  11. 116471
    “…Kisspeptin neurones in the posterodorsal sub-nucleus of the medial amygdala (MePD) are thought to modulate pubertal timing and anxiety.We test the hypothesis that psychosocial stress, processed by the MePD, is relayed to theGnRH pulse generator to delay puberty. Female mice were exposed to predator odour, 2,4,5-Trimethylthiazole (TMT), for 14 days from postnatal day (pnd) 21 and pubertal onset wasmonitored. …”
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    SUN-LB49 Chronic Exposure to Predator Odour Stress Disrupts LH Pulsatility and Delays Puberty While Activation of Amygdala Kisspeptin Advances Puberty
  12. 116472
    “…The remaining pups were exposed to hypoxia (8% O2) or normoxia (time control) for 30 or 60 min at which times trunk blood was collected for the measurement of plasma glucose, insulin, ACTH, and corticosterone. …”
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    SUN-214 A Novel Glucocorticoid Receptor Antagonist (CORT113176) Reveals Unique Developmental and Tissue-Specific Effects in a Neonatal Rat Model of Human Prematurity
  13. 116473
    “…This side effect is predominantly found in patients exposed to blockade of the PD-1/PD-Ligand pathway. …”
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    SAT-674 Anti PD1 Induced Type 1 Diabetes
  14. 116474
    “…The majority of those in the insufficient (70%) or at risk (80%) groups were exposed to topical, nasal or inhaled corticosteroids, but not systemic. …”
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    SAT-104 Unraveling the Connection Between Cortisol and Pediatric Idiopathic Intracranial Hypertension
  15. 116475
    “…All participants belonged to the same family, lived in the same small island, therefore exposed to similar environmental conditions. Family members with disorders known to affect lipid metabolism as well as a history of drinking habits of more 30 g alcohol/day were excluded. …”
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    OR01-06 Resistance to Thyroid Hormone Beta Is Associated with an Increase in Hepatic Fat Measured by Transient Elastography (Fibroscan(®)) with Controlled Attenuation Parameter (CAP)
  16. 116476
    “…PT tissue fragments matched for viability, mass, and cellular content were placed on permeable membranes and exposed to a series of extracellular calcium concentrations over equivalent time intervals of challenge and normocalcemic recovery to interrogate dynamic PTH secretory induction or suppression. …”
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    OR07-04 A Novel Ex Vivo Live-Cell Interrogative Assay of Human Parathyroid Tissue Reveals Distinct Mechanisms of Calcium Sensing Failure in Primary, Secondary, and Tertiary Hyperparathyroidism
  17. 116477
    “…Adult F1 progeny of P. argentipes were exposed to different concentrations of DDT, malathion, deltamethrin and propoxur using WHO susceptibility bioassay kits. …”
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    Insecticide susceptibility of the sand fly leishmaniasis vector Phlebotomus argentipes in Sri Lanka
  18. 116478
    “…Cumulative antifungal exposure was calculated as the total number of exposed months. MAIN OUTCOMES AND MEASURES: Primary outcomes were the first SCC or BCC reported to the transplant registry by transplant centers. …”
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    Voriconazole and the Risk of Keratinocyte Carcinomas Among Lung Transplant Recipients in the United States
  19. 116479
    “…However, less consistent changes were observed for athletes exposed to repeated, high-level head impacts, warranting further investigation.…”
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    THE EFFECTS OF INTERNAL JUGULAR VEIN COMPRESSION FOR PRESERVING WHITE MATTER INTEGRITY IN HIGH SCHOOL FOOTBALL PLAYERS COMPARISON OF HIGH VS LOW
  20. 116480
    “…In the social interaction test animals were individually exposed to water or MK-801 for 20 min and then placed for 7 min in a tank flanked by two identical tanks either empty or containing 10 zebrafish serving as social stimuli. …”
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    S30. SCHIZOPHRENIA IN A FISH: EFFECTS OF NMDA ANTAGONISM ON LOCOMOTOR BEHAVIOR AND SOCIAL INTERACTION IN ZEBRAFISH
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