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  1. 117201
    “…Sarcopenia, the loss of skeletal muscle mass and function, is a frequent finding in patients chronically exposed to glucocorticoids. Patients with active Cushing’s syndrome (CS) show reduced muscle mass and weakness. …”
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    MON-LB073 The Serum Creatinine to Serum Cystatin C Ratio Is a Reliable Surrogate Marker of Sarcopenia in Patients with Cushing's Syndrome in Remission
  2. 117202
    por Zoubovsky, Sandra, Muglia, Louis
    Publicado 2019
    “…From gestational day 6.5 to 17.5, pregnant C57Bl/6 female mice were exposed to a novel chronic stress paradigm consisting of variable psychosocial stressors such as foreign object exposure, rat odor exposure, bedding removal and were assessed from postpartum day 2 to 7 for behavioral alterations in maternal care, depression, and anxiety as well as circadian and brief restraint-stress associated corticosterone response. mRNA changes in molecular regulators of the HPA axis were measured in 1mm micropunches of the hypothalamic paraventricular nucleus (PVN) via qPCR. …”
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    SUN-021 Chronic Psychosocial Stress during Pregnancy Affects Maternal Behavior and Neuroendocrine Function and Modulates Hypothalamic CRH Signaling Pathway and Nuclear Steroid Hormone Receptor Expression
  3. 117203
    “…In the primary analyses, patients were defined as exposed from treatment start throughout follow-up (analogous to intention to treat); additional analyses were conducted with an as-treated exposure definition. …”
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    Use of sodium glucose cotransporter 2 inhibitors and risk of major cardiovascular events and heart failure: Scandinavian register based cohort study
  4. 117204
    “…The incidence of CIN2+ patients exposed to passive smoking was significantly different from that of CIN1- patients. …”
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    Plasma expression of miRNA-21, − 214, −34a, and -200a in patients with persistent HPV infection and cervical lesions
  5. 117205
    “…Mitochondrial oxidative stress, measured as a decrease in aconitase activity, was significantly increased in cells exposed to Hb (~43% aconitase activity reduction after 72h 20μM Hb treatment, and ~11% aconitase activity reduction after 72h 1μM Hb treatment). …”
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    3329 Hemoglobin selectively inhibits renal proximal tubular uptake of proteins: Implications for vitamin D deficiency and kidney disease in sickle cell disease
  6. 117206
    “…CONCLUSION: These studies demonstrate the proof of concept of artemisinin therapeutic potential to improve survival in vitro of BMSCs exposed to ROS-induced apoptosis and suggest that artemisinin-mediated protection occurs via the activation of c-Raf-Erk1/2-p90(rsk)-CREB signaling pathway.…”
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    Protective mechanism of artemisinin on rat bone marrow-derived mesenchymal stem cells against apoptosis induced by hydrogen peroxide via activation of c-Raf-Erk1/2-p90(rsk)-CREB pathway
  7. 117207
    “…This study explored changes in brain activity in rats exposed to a sustained HH environment using functional magnetic resonance imaging (fMRI). …”
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    Abnormal brain activity in rats with sustained hypobaric hypoxia exposure: a resting-state functional magnetic resonance imaging study
  8. 117208
    “…The rats in group G1 had their bile duct exposed without ligation, the rats in group G2 underwent total bile duct ligation, and the rats in group G3 were given a gavage of YCHD. …”
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    Yinchenhao decoction attenuates obstructive jaundice-induced liver injury and hepatocyte apoptosis by suppressing protein kinase RNA-like endoplasmic reticulum kinase-induced pathway
  9. 117209
    “…Offspring of mothers with diabetes had a 29% increased overall rate of early onset CVD (hazard ratio 1.29 (95% confidence interval 1.21 to 1.37); cumulative incidence among offspring unexposed to maternal diabetes at 40 years of age 13.07% (12.92% to 13.21%), difference in cumulative incidence between exposed and unexposed offspring 4.72% (2.37% to 7.06%)). …”
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    Maternal diabetes during pregnancy and early onset of cardiovascular disease in offspring: population based cohort study with 40 years of follow-up
  10. 117210
    “…METHODS: Forty male mice were randomly divided into smoking group and non-smoking group, and the smoking group was exposed to cigarette smoke for 2 h per day for 90 days. …”
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    Dysbiosis of lower respiratory tract microbiome are associated with inflammation and microbial function variety
  11. 117211
    “…The expression of [Formula: see text] and related downstream proteins was detected in adult rat brain exposed to MeHg ([Formula: see text]) for [Formula: see text] in vivo. …”
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    Acute Methylmercury Exposure and the Hypoxia-Inducible [Formula: see text] Signaling Pathway under Normoxic Conditions in the Rat Brain and Astrocytes in Vitro
  12. 117212
    “…A deep sterile rectal swab exposed only to the rectum was collected immediately at birth before colostrum feeding (i.e., d 0), and fecal samples at d 14, 28, and 42 (prior to weaning) for microbiome and untargeted metabolome analyses using 16S rRNA gene sequencing and LC-MS. …”
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    Residual feed intake divergence during the preweaning period is associated with unique hindgut microbiome and metabolome profiles in neonatal Holstein heifer calves
  13. 117213
    “…METHODS: Human hepatoma cell line HepG2 cells were exposed to palmitic acid (PA) with or without oleic acids (OA) or/and endoplasmic reticulum (ER) stress inhibitor tauroursodeoxycholic acid (TUDCA) for 24 h. …”
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    Oleic acid ameliorates palmitic acid induced hepatocellular lipotoxicity by inhibition of ER stress and pyroptosis
  14. 117214
    “…Rectal temperatures (T(REC), °C) of 60 purebred Angus cattle (30 heifers, 30 steers; 235.2 ± 5.11 kg) were recorded at 20 s intervals from 30 min prior to handling until two hours post handling. All cattle were exposed to a standardized handling procedure consisting of (i) being restrained in a weighing box for 30 s; (ii) being held within the crush for 30 s; and then (iii) being restrained in a head bail for 60 s. …”
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    The Influence of Temperament on Body Temperature Response to Handling in Angus Cattle
  15. 117215
    “…RESULTS: Ex-vivo gill filament culture was exposed to Leibovitz’s L-15 medium (300 mOsmol l(− 1)) or the medium with an adjusted osmolality of 600 mOsmol l(− 1) for 4, 8 and 24 h. …”
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    Genome-wide analysis of MicroRNA-messenger RNA interactome in ex-vivo gill filaments, Anguilla japonica
  16. 117216
    “…Finally, future studies should consider designing interventions that target suicide-related outcomes in those exposed to suicide and that include efforts to mitigate the adverse effects of exposure to suicide attempt on subsequent suicide attempt outcomes.…”
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    Association of suicidal behavior with exposure to suicide and suicide attempt: A systematic review and multilevel meta-analysis
  17. 117217
    “…Serial interval estimates were based on previous studies of severe acute respiratory syndrome coronavirus (SARS-CoV). A susceptible-exposed-infectious-recovered metapopulation model was used to simulate the epidemics across all major cities in China. …”
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    Nowcasting and forecasting the potential domestic and international spread of the 2019-nCoV outbreak originating in Wuhan, China: a modelling study
  18. 117218
    “…Median age was 49·0 years (IQR 41·0–58·0). 27 (66%) of 41 patients had been exposed to Huanan seafood market. One family cluster was found. …”
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    Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China
  19. 117219
    “…Thus, interventions to promote mental well-being in health care professionals exposed to COVID-19 need to be immediately implemented, and to strengthen prevention and response strategies by training health care professionals on mental help and crisis management.…”
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    Les professionnels de santé face à la pandémie de la maladie à coronavirus (COVID-19) : quels risques pour leur santé mentale ?
  20. 117220
    “…INTERPRETATION: Seroprevalence of MERS-CoV antibodies was significantly higher in camel-exposed individuals than in the general population. …”
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    Presence of Middle East respiratory syndrome coronavirus antibodies in Saudi Arabia: a nationwide, cross-sectional, serological study
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