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  1. 117221
    “…Similarly, HUVEC acutely exposed to high glucose (HG, 25 mM) activated both canonical (IκB-α degradation, normal vs. …”
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    OR14-06 Inhibition of Protein Kinase C-beta2 Phosphorylation Restores Nuclear Factor-Kappa B Activation and Improves Peripheral Arterial Disease in Diabetes
  2. 117222
    “…METHODS: Transcriptomic, functional annotation and qRT-PCR studies were performed on JQ1-exposed TNBC cells in culture. The results obtained were confirmed in spheroids and spheroid-derived tumours. …”
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    Identification of a stemness-related gene panel associated with BET inhibition in triple negative breast cancer
  3. 117223
    “…METHODS: Wistar rats were kept isolated or grouped (n=10/group) from weaning (21 days after birth) to 10 weeks and then exposed to the Open Field Test to assess locomotion. …”
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    M9. RATS REARED IN SOCIAL ISOLATION INDUCES EPIGENETIC MODIFICATIONS IN THE NMDA RECEPTOR SUBUNITS
  4. 117224
    “…Some authors argue that the risk of developing psychosis is higher in subjects who were exposed to multiple types of ACEs and that trauma multiplicity has a negative clinical impact in psychosis, while others argue that specific types of trauma are related to specific features of disease, taking away importance at the dose-response hypothesis. …”
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    T184. THE ROLE OF ADVERSE CHILDHOOD EXPERIENCES IN THE DEVELOPMENT OF A MORE SEVERE TYPE OF SCHIZOPHRENIA
  5. 117225
    “…DISCUSSION: While it is expected that some TRS patients might not receive clozapine, the observation that non-TRS patients had been exposed to clozapine may surprise. A possible explanation may be the lack of systematized procedure to diagnose TRS, which is often merely coincident with a nonspecific lack of response to antipsychotics. …”
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    S202. PROXIMAL AND DISTAL FACTORS ASSOCIATED WITH CLOZAPINE EXPOSURE IN A SAMPLE OF TREATMENT RESISTANT AND TREATMENT RESPONSIVE SCHIZOPHRENIA PATIENTS
  6. 117226
    “…SSP inpatients were 11.6 times more likely to have been exposed to severe CT than HCs. Within the SSP group, CT was associated with increased ToM2 deficits (U = 259, p = .020), while polytraumatization was negatively correlated to both ToM1 (rs = -.297, p = .020) and ToM2 (rs = -.341, p = .007) performance. …”
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    T106. CHILDHOOD TRAUMA IS ASSOCIATED WITH THEORY OF MIND IMPAIRMENT IN SCHIZOPHRENIA-SPECTRUM PSYCHOSIS
  7. 117227
    “…In order to calculate the PERS, we used data corresponding to the nine variables that are consider on the score, being respectively, winter or spring birth, urbanicity, cannabis use, advanced paternal age, obstetric and perinatal complications, physical and sexual abuse, neglect and paternal death, therefore if the person is exposed to one or more enviromic factor the odds ratio corresponding to that factor are added up and divided by all factors considered on the calculation, generating the final score. …”
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    S174. POLYENVIRONMENTAL AND POLYGENIC RISK SCORES AND THE EMERGENCE OF PSYCHOTIC EXPERIENCES IN CHILDREN AND ADOLESCENTS
  8. 117228
    “…Brain sections were treated with the radioligands and x-ray sensitive films were exposed to the brain sections and radioactivity standards for 4 (flumazenil) or 8 (Ro15-4513) weeks. …”
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    T180. REDUCED [3H]RO15-4513 RECEPTOR BINDING IN THE VENTRAL HIPPOCAMPUS IN THE MAM DEVELOPMENTAL DISRUPTION MODEL OF SCHIZOPHRENIA
  9. 117229
    “…RESULTS: The overall sample included 725 healthy volunteers (mean [SD] age, 28.3 [3.6] years; 533 [73.6%] male) exposed to the ketamine and placebo conditions. Racemic ketamine or S-ketamine was associated with a statistically significant increase in transient psychopathology in healthy participants for total (SMD = 1.50 [95% CI, 1.23-1.77]; P < .001), positive (SMD = 1.55 [95% CI, 1.29-1.81]; P < .001), and negative (SMD = 1.16 [95% CI, 0.96-1.35]; P < .001) symptom ratings relative to the placebo condition. …”
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    Association of Ketamine With Psychiatric Symptoms and Implications for Its Therapeutic Use and for Understanding Schizophrenia: A Systematic Review and Meta-analysis
  10. 117230
    por Bayham, Jude, Fenichel, Eli P
    Publicado 2020
    “…We accounted for the occupation within the health-care sector, state, and household structure to identify the segments of the health-care workforce that are most exposed to child-care obligations from school closures. …”
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    Impact of school closures for COVID-19 on the US health-care workforce and net mortality: a modelling study
  11. 117231
    “…The only epitopes displayed after immunostaining are the “exposed” epitopes, not “hidden” by the fixation of chromatin higher-order structure. …”
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    Linker histone epitopes are hidden by in situ higher-order chromatin structure
  12. 117232
    “…Despite common industry knowledge regarding the correct adjustment of nosebands, there seems to be a trend of overtightening nosebands and exposing horses to high pressures that restrict normal behaviours. …”
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    The Reported Use of Nosebands in Racing and Equestrian Pursuits
  13. 117233
    “…BACKGROUND: We are exposed to several chemicals such as persistent organic pollutants (POPs) in our everyday lives. …”
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    Persistent organic pollutants, pre-pregnancy use of combined oral contraceptives, age, and time-to-pregnancy in the SELMA cohort
  14. 117234
    “…The HIV-prevalence among adults was 17.5% (95%CI: 15.8–19.4) and 6.1% (95%CI: 3.1–11.4) among HIV-exposed children. HIV prevalence was higher among women than among men (20.9% vs. 13.5%, p < 0.001). …”
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    HIV epidemic and cascade of care in 12 east African rural fishing communities: results from a population-based survey in Uganda
  15. 117235
    “…Data analysis was performed from March to April 2020. EXPOSURE: Exposed participants were those who viewed the infographics and/or video. …”
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    Association of a Public Health Campaign About Coronavirus Disease 2019 Promoted by News Media and a Social Influencer With Self-reported Personal Hygiene and Physical Distancing in the Netherlands
  16. 117236
    “…BACKGROUND: Preterm newborns can be exposed early to significant perinatal stress, and this stress can increase the risk of altered socioemotional development. …”
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    Interactive Guidance Intervention to Address Sustained Social Withdrawal in Preterm Infants in Chile: Protocol for a Randomized Controlled Trial
  17. 117237
    “…BACKGROUND: Health-care workers are thought to be highly exposed to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. …”
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    Risk of COVID-19 in health-care workers in Denmark: an observational cohort study
  18. 117238
    “…HIV testing uptake among MSM and TW exposed to digital interventions was 1.5 times higher than that of unexposed MSM and TW (risk ratio [RR] 1.5; 95% CI 1.3-1.7). …”
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    Using Digital Communication Technology to Increase HIV Testing Among Men Who Have Sex With Men and Transgender Women: Systematic Review and Meta-Analysis
  19. 117239
    “…Patient information collected during dental care exposes many of the challenges that confront a wider scale approach. …”
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    Structuring, reuse and analysis of electronic dental data using the Oral Health and Disease Ontology
  20. 117240
    “…METHODS: An epidemiological model with five compartments (susceptible–exposed–symptomatic–asymptomatic–recovered/removed [SEIAR]) was developed based on observed transmission features. …”
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    A five-compartment model of age-specific transmissibility of SARS-CoV-2
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