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118421“…Peripheral artery disease (PAD) is atherosclerotic occlusion of vessel outside the heart and most commonly affects the lower extremities. Diabetes (DM) accelerates the course and severity of PAD. …”
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118422“…Fatal outcomes are extremally rare, with an incidence around 0.001%. The hepatotoxic effects of clozapine have received considerable less attention than its cardiometabolic and hematologic counterparts. …”
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118423por Barone, Annarita, Iasevoli, Felice, Matrone, Marta, Filomena Buonaguro, Elisabetta, Falco, Mariateresa, Genesio, Rita, Pignataro, Piero, Capasso, Mario, Gambale, Antonella, Avagliano, Camilla, Razzino, Eugenio, Notar Francesco, Danilo, Ciccarelli, Mariateresa, Vitiello, Giuseppina, Andolfo, Immacolata, Nitsch, Lucio, Iolascon, Achille, de Bartolomeis, Andrea“…Genome-Wide Association Studies (GWAS) on extremely large samples of patients identified and replicated hundreds of Single-Nucleotide Polymorphism (SNPs), each exhibiting only a modest effect. …”
Publicado 2020
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118424por Mahavir Agarwal, Sri, Panda, Roshni, Costa-Dookhan, Kenya, Mackenzie, Nicole, Casuccio-Treen, Quinn, Caravaggio, Fernando, Eyesha, Hashim, Kirpalani, Anish, Chintoh, Araba, Voineskos, Aristotle, Kramer, Caroline, Graff-Guerrero, Ariel, Remington, Gary, Hahn, Margaret“…In conclusion, our findings support glucose lowering effects of metformin in SMI patients with early onset prediabetes/T2D, but raise the issue of treatment initiation before the development of overt glucose dysregulation to obtain maximum benefits on adiposity reduction. Given the extremely high rates of T2D in patients with SMI, future adequately powered trials are required to examine metabolic interventions in relation to CV risk factors, and also other related domains such as cognitive function in this highly under-researched population.…”
Publicado 2020
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118425por Stasi, Sophia, Stamou, Magdalini, Papathanasiou, George, Frantzeskaki, Paraskevi, Kanavas, Emmanouil, Evaggelou-Sossidis, George, Gouskos, Adamantios, Palantzas, Andreas, Poursanidis, Kyriakos, Macheras, George A.“…Construct validity was tested against Greek versions of the Lower Extremity Functional Scale (LEFS-Greek), Modified Harris Hip Score (MHHS-Gr), and the 30 s chair-to-stand, Timed Up & Go (TUG), and 9-stairs-ascend/descend (9S-A/D) tests. …”
Publicado 2020
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118426por Benedetti, Francesca, Pachetti, Maria, Marini, Bruna, Ippodrino, Rudy, Gallo, Robert C., Ciccozzi, Massimo, Zella, Davide“…We also observed a statistically significant correlation between population density and number of deaths/1 M people both in the month of March (p = 0.0297) and in the month of April (p = 0.0116), when three areas extremely populated (NYC, Los Angeles and Washington DC) were included in the calculation. …”
Publicado 2020
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118427por Rosales, Xiomara Q., Thompson, John L. P., Haas, Richard, Van Hove, Johan L. K., Karaa, Amel, Krotoski, Danuta, Engelstad, Kristin, Buchsbaum, Richard, DiMauro, Salvatore, Hirano, Michio“…Since individual mitochondrial disorders are often extremely rare, major communication and recruitment efforts are required. …”
Publicado 2020
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118428por Jiang, Guozhi, Luk, Andrea O., Tam, Claudia H. T., Lau, Eric S., Ozaki, Risa, Chow, Elaine Y. K., Kong, Alice P. S., Lim, Cadmon K. P., Lee, Ka Fai, Siu, Shing Chung, Hui, Grace, Tsang, Chiu Chi, Lau, Kam Piu, Leung, Jenny Y. Y., Tsang, Man-wo, Kam, Grace, Lau, Ip Tim, Li, June K., Yeung, Vincent T., Lau, Emmy, Lo, Stanley, Fung, Samuel K. S., Cheng, Yuk Lun, Chow, Chun Chung, Pearson, Ewan R., So, Wing Yee, Chan, Juliana C. N., Ma, Ronald C. W.“…Risk of progression was associated with extremes of BMI and high HbA1c. On multivariate Cox analysis, early age at diagnosis, microvascular complications, high triglyceride levels, and tobacco use were additional independent predictors for glycemic progression. …”
Publicado 2020
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118429por LaPiana, Nina, Duong, Alvin, Lee, Alex, Alschitz, Leon, Silva, Rafael M L, Early, Jody, Bunnell, Aaron, Mourad, Pierre“…METHODS: Patients aged 50 to 70 years, all of whom experienced motor deficits after acute ischemic stroke, participated in 3 optional therapy sessions using augmented reality therapeutic gaming over the course of 1 week, targeting deficits in upper extremity strength and range of motion. After completion of the game, we administered a 16-item questionnaire to the patients to assess the game’s acceptability; 8 questions were answered by rating on a scale from 1 (very negative experience) to 5 (very positive experience); 8 questions were qualitative. …”
Publicado 2020
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118430por Gibbs, Sarah N., Shah, Shweta, Deshpande, Chinmay G., Bensink, Mark E., Broder, Michael S., Dumas, Paula K., Buse, Dawn C., Vo, Pamela, Schwedt, Todd J.“…Almost all (962/1101 (87%)) experienced sleep difficulties and 41% (448/1101) (48% (336/697) of those with 2 or more preventive treatment failures) were very or extremely fearful of a next migraine attack. Median (25th percentile, 75th percentile) monthly out‐of‐pocket costs of $90.00 ($30.00, $144.00) in doctor’s fees (n = 504), $124.00 ($60.00, $234.00) in health insurance (n = 450), $40.00 ($20.00, $100.00) for prescriptions (n = 630), and $50.00 ($0.00, $100.00) for complementary therapies (n = 255) were reported. …”
Publicado 2020
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118431por Ryan, Neil A. J., McMahon, Raymond, Tobi, Simon, Snowsill, Tristan, Esquibel, Shona, Wallace, Andrew J., Bunstone, Sancha, Bowers, Naomi, Mosneag, Ioana E., Kitson, Sarah J., O’Flynn, Helena, Ramchander, Neal C., Sivalingam, Vanitha N., Frayling, Ian M., Bolton, James, McVey, Rhona J., Evans, D. Gareth, Crosbie, Emma J.“…The main limitation of the study was failure to conduct MMR germline sequencing for the whole study population, which means that the sensitivity and specificity of tumour triage strategies for LS detection may be overestimated, although the risk of LS in women with no clinical or tumour predictors is expected to be extremely low. CONCLUSIONS: In this study, we observed that age, family history, and histology are imprecise clinical correlates of LS-EC. …”
Publicado 2020
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118432“…BACKGROUND: Indonesia is the only country in the Asia Pacific region where the incidence of HIV is still on the rise, and its prevalence is extremely high among the key populations such as men who have sex with men, transgender women, and people who inject/use drugs. …”
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118433por Wang, Yafeng, Huang, Wentao, O’Neil, Adrienne, Lan, Yutao, Aune, Dagfinn, Wang, Wei, Yu, Chuanhua, Chen, Xiong“…RESULTS: Absolute mortality rate was higher in adults with diabetes and extremes of sleep duration (≤5 h/day, 215.0 per 10,000 person-years; ≥10 h/day, 363.5 per 10,000 person-years). …”
Publicado 2020
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118434por Cotic, Matthias, Ksoll, Korbinian, Achtnich, Andrea, Beitzel, Knut, Seiberl, Wolfgang, Imhoff, Andreas B., Schwirtz, Ansgar, Kreuzpointner, Florian“…Exclusion criteria were Genu varum or Genu val-gum and pathologies which might affect coordination abilities of the lower extremities. Knee flexion angle was captured with a 3D motion analysis system (Vicon Motion Systems, Oxford,UK). …”
Publicado 2020
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118435“…To accomplish this, all patients were supported with specific training-protocols for further rehabilitation of the lower extremity. These protocols were individually set-up, however in nearly all patients a specific emphasize was on strengthening of the hip external rotators.…”
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118436por Huang, He, Chen, Li Min, Fang, Xiao Jie, Guo, Cheng Cheng, Lin, Xiao Ping, Hong, Huang Ming, Li, Xi, Wang, Zhao, Tian, Ying, Chen, Mei Ting, Yao, Yu Yi, Chen, Zegeng, Li, Xiao Qian, Pan, Fei“…BACKGROUND: Extranodal natural killer/T-cell lymphoma (ENKTL) is a rare and extremely malignant tumor. The systemic inflammation score (SIS), which is based on the pretreatment level of lymphocyte-to-monocyte ratio (LMR) and serum albumin (Alb), has been shown to be of prognostic value in a number of cancers. …”
Publicado 2020
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118437por Najfeld, Michael, Hube, Robert, Kujat, Ann-Kathrin, Mayr, Hermann Otto, Thiele, Kathi“…In terms of range of motion, the LIA group showed a higher active range of motion at the operated extremity than the FNB group during the hospital stay. …”
Publicado 2020
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118438por Inagaki, Takayuki, Asahi, Shoki, Ogawa, Kenji, Nakagawa, Taku, Nikai, Toshiaki, Yamada, Kiyofumi, Yagi, Tetsuya, Uchiya, Kei-ichi“…ARMS-LAMP may be a new clinically beneficial POCT technology for examination that is novel and extremely practical. DISCLOSURES: All Authors: No reported disclosures…”
Publicado 2020
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118439por Garris, Cindy, D’Amico, Ronald, Wannamaker, Paul, Mpofu, Nobuhle, McHorney, Colleen A, Mansukhani, Sonal, Flamm, Jason, Thedinger, Blair, Benson, Paul, Chiriboga-Salazar, Daniela M, Czarnogorski, Maggie“…At M4, 84% of patients reported that monthly clinic visits were very/extremely acceptable and 66% reported no logistical challenges to clinic administered CAB+RPV LA. …”
Publicado 2020
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118440por Pappas, Peter G, Spec, Andrej, Miceli, Marisa H, Proia, Laurie, Arauz, Ana Belen, Hayes, Justin, Peinhardt, Alisa, McMullen, Rachel, Moore, Mary K, McGwin, Gerald, Thompson III, George R“…Drug-related AEs and tolerability were similar in both arms (Table 1). Lower extremity edema, hypertension, nausea, and anorexia were the most common AEs. …”
Publicado 2020
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