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461por Huang, Stanley Ching-Cheng, Freitas, Tori C., Amiel, Eyal, Everts, Bart, Pearce, Erika L., Lok, James B., Pearce, Edward J.“…We show that oxygen consumption rates (OCR) and egg production are significantly diminished by pharmacologic inhibition of carnitine palmitoyl transferase 1 (CPT1), which catalyzes a rate limiting step in fatty acid β-oxidation (FAO) and by genetic loss of function of acyl CoA synthetase, which complexes with CPT1 and activates long chain FA for use in FAO, and of acyl CoA dehydrogenase, which catalyzes the first step in FAO within mitochondria. …”
Publicado 2012
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462“…Interestingly, several transcription factors or co-activators exert transcriptional control on both FAO and RC genes, and can be activated by small molecules, opening to possibly common therapeutic approaches for FAO and RC deficiencies. …”
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463Publicado 2000“…Boletín de tierras y aguas de la FAO ;…”
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465por van Eunen, Karen, Volker-Touw, Catharina M. L., Gerding, Albert, Bleeker, Aycha, Wolters, Justina C., van Rijt, Willemijn J., Martines, Anne-Claire M. F., Niezen-Koning, Klary E., Heiner, Rebecca M., Permentier, Hjalmar, Groen, Albert K., Reijngoud, Dirk-Jan, Derks, Terry G. J., Bakker, Barbara M.“…BACKGROUND: Defects in genes involved in mitochondrial fatty-acid oxidation (mFAO) reduce the ability of patients to cope with metabolic challenges. mFAO enzymes accept multiple substrates of different chain length, leading to molecular competition among the substrates. …”
Publicado 2016
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466por Nallanthighal, Sameera, Rada, Miran, Heiserman, James Patrick, Cha, Jennifer, Sage, Jessica, Zhou, Bo, Yang, Wei, Hu, Ye, Korgaonkar, Chaitali, Hanos, Christina Terpsithea, Ashkavand, Zahra, Norman, Kenneth, Orsulic, Sandra, Cheon, Dong-Joo“…We identified that fatty acid β-oxidation (FAO) is upregulated by COL11A1 in ovarian cancer cells and that COL11A1-driven cisplatin resistance can be abrogated by inhibition of FAO. …”
Publicado 2020
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467“…FAO-related genes were further examined in the liver of the fetuses and in the offspring at weaning. …”
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468por Koç, Deniz Levent“…Reference evapotranspiration (ETo) is essential for irrigation practices and the management of water resources and plays a vital role in agricultural and hydro-meteorological studies. The FAO-56 Penman-Monteith (PM) equation, recommended as the sole standard method of calculating ETo by the Food and Agriculture Organization of the United Nations (FAO), is the most commonly used and accurate model to determine the ETo and evaluate ETo equations. …”
Publicado 2022
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469por Kim, Ki Chun, Behrens, Andrew, Braza, Samuel, Ehret, Amanda, Carvalho, Kepler, Mansur, Nacime SB, Dibbern, Kevin N., Ellis, Scott J., Lalevée, Matthieu, Netto, Cesar de Cesar“…We found that all isolated procedures significantly decreased FAO measurements, with every 1mm increase in MDCO, LCL and CO decreasing FAO by respectively 0.8%, 0.36%, and 0.29%. …”
Publicado 2022
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470por Tonga, K. O., King, G. G., Farah, C. S., Thamrin, C., Tang, F. S., Santos, J., Sharma, P., Chapman, D. G., Oliver, B. G.“…Subjects demonstrated moderate FAO, abnormal FOT indices and loss of lung elastic recoil. …”
Publicado 2018
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471por Giachin, Gabriele, Jessop, Matthew, Bouverot, Romain, Acajjaoui, Samira, Saïdi, Melissa, Chretien, Anaïs, Bacia‐Verloop, Maria, Signor, Luca, Mas, Philippe J., Favier, Adrien, Borel Meneroud, Eve, Hons, Michael, Hart, Darren J., Kandiah, Eaazhisai, Boeri Erba, Elisabetta, Buisson, Alain, Leonard, Gordon, Gutsche, Irina, Soler‐Lopez, Montserrat“…Fatty acid β‐oxidation (FAO) and oxidative phosphorylation (OXPHOS) are mitochondrial redox processes that generate ATP. …”
Publicado 2021
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472por Yan, Chaojun, Gao, Ronghui, Gao, Chuan, Hong, Kai, Cheng, Meng, Liu, Xiaojing, Zhang, Qing, Zhang, Jing“…Further, we showed that depletion of FDXR or FAO inhibitor etomoxir treatment reduced primary and endocrine-resistant breast cancer cell growth. …”
Publicado 2023
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473por Tian, Geer, Zhou, Junteng, Quan, Yue, Kong, Qihang, Li, Junli, Xin, Yanguo, Wu, Wenchao, Tang, Xiaoqiang, Liu, Xiaojing“…The decrease in FAO may be attributed to reduced long-chain fatty acid (LCFA) uptake. …”
Publicado 2023
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474“…Significant synergy was detected for stilbenes with FAO increase in adipocytes by 60–70% (p<0.05) and in myotubes >2000% (p<0.01). …”
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475por Huang, Shu-Yi, Chou, Pai-Chien, Wang, Tsai-Yu, Lo, Yu-Lun, Joa, Wen-Ching, Chen, Li-Fei, Sheng, Te-Fang, Chung, Kian Fan, Wang, Chun-Hua, Kuo, Han-Pin“…Asthmatic patients with fixed airway obstruction (FAO) and patients with chronic obstructive pulmonary disease (COPD) share similarities in terms of irreversible pulmonary function impairment. …”
Publicado 2016
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476por Wang, Ming-Da, Wu, Han, Huang, Shuai, Zhang, Hui-Lu, Qin, Chen-Jie, Zhao, Ling-Hao, Fu, Gong-Bo, Zhou, Xu, Wang, Xian-Ming, Tang, Liang, Wen, Wen, Yang, Wen, Tang, Shan-Hua, Cao, Dan, Guo, Lin-Na, Zeng, Min, Wu, Meng-Chao, Yan, He-Xin, Wang, Hong-Yang“…Finally, HBx-induced activation of the AMPK and FAO pathways were also observed in xenograft tumors and HBV-associated HCC specimens. …”
Publicado 2016
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477por He, Wanming, Liang, Bishan, Wang, Chunlin, Li, Shaowei, Zhao, Yang, Huang, Qiong, Liu, Zexian, Yao, Zhiqi, Wu, Qijing, Liao, Wangjun, Zhang, Shuyi, Liu, Yajing, Xiang, Yi, Liu, Jia, Shi, Min“…These results suggest that FAO plays an important role in MSC-mediated stemness and chemotherapy resistance in GC and FAO inhibitors in combination with chemotherapeutic drugs present as a promising strategy to overcome chemoresistance.…”
Publicado 2019
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478por Faulkner, Ashton, Lynam, Eleanor, Purcell, Robert, Jones, Coleen, Lopez, Colleen, Board, Mary, Wagner, Kay-Dietrich, Wagner, Nicole, Carr, Carolyn, Wheeler-Jones, Caroline“…In HUVEC monolayers, flux analysis revealed that VEGF-A promoted glycolysis at the expense of fatty acid oxidation (FAO), whereas GW0742 reduced both glycolysis and FAO. …”
Publicado 2020
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479por Stenlid, Rasmus, Olsson, David, Cen, Jing, Manell, Hannes, Haglind, Charlotte, Chowdhury, Azazul Islam, Bergsten, Peter, Nordenström, Anna, Halldin, Maria“…Carnitine uptake deficiency (CUD) disturbs the transportation of fatty acids into the mitochondria, but when treated is a mild disease without significant effects on FAO. For improved clinical care of VLCAD in particular, estimation of FAO severity could be important. …”
Publicado 2021
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480“…Metabolomic analysis revealed that VPA -induced abnormal liver function resulted in the accumulation of serum long-chain acylcarnitines (LCACs), and the reduced expression of β-FAO relevant genes (Carnitine palmitoyltrans-ferase (CPT)1, CPT2 and Long-chain acyl-CoA dehydrogenase (LCAD)), indicating the disruption of β-FAO. …”
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