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1021por Sikder, Kunal, Shukla, Sanket Kumar, Patel, Neel, Singh, Harpreet, Rafiq, Khadija“…BACKGROUND/AIMS: Systemic hyperlipidemia and intracellular lipid accumulation induced by chronic high fat diet (HFD) leads to enhanced fatty acid oxidation (FAO) and ketogenesis. The present study was aimed to determine whether activation of peroxisome proliferator-activated receptor-γ (PPAR-γ) by surplus free fatty acids (FA) in hyperlipidemic condition, has a positive feedback regulation over FAO and ketogenic enzymes controlling lipotoxicity and cardiac apoptosis. …”
Publicado 2018
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1022por Xu, Wenli, Wu, Ye, Wang, Li, Bai, Yan, Du, Yunhui, Li, Yang, Cao, Ning, Zhao, Yuhui, Zhang, Youyi, Liu, Huirong“…In vitro, β(1)-AA promoted nTreg cell differentiation by up-regulating mitochondrial fatty acid oxidation (FAO) in activated CD4(+) T cells via AMP-activated protein kinase (AMPK) activation and mitochondrial membrane potential reduction. …”
Publicado 2019
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1023por Li, Zhi, Li, He, Zhao, Zhi-Bo, Zhu, Wei, Feng, Pan-Pan, Zhu, Xi-Wen, Gong, Jian-Ping“…CONCLUSIONS: Overall, our results demonstrate that downregulation of SIRT4 in TAMs modulates the alternative activation of macrophages and promotes HCC development via the FAO-PPARδ-STAT3 axis. These results could provide a new therapeutic target for the treatment of HCC.…”
Publicado 2019
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1024por Knutsen, Helle Katrine, Alexander, Jan, Barregård, Lars, Bignami, Margherita, Brüschweiler, Beat, Ceccatelli, Sandra, Cottrill, Bruce, Dinovi, Michael, Edler, Lutz, Grasl‐Kraupp, Bettina, Hoogenboom, Laurentius (Ron), Nebbia, Carlo Stefano, Oswald, Isabelle P, Petersen, Annette, Rose, Martin, Roudot, Alain‐Claude, Schwerdtle, Tanja, Vleminckx, Christiane, Vollmer, Günter, Wallace, Heather, Lampen, Alfonso, Morris, Ian, Piersma, Aldert, Schrenk, Dieter, Binaglia, Marco, Levorato, Sara, Hogstrand, Christer“…The CONTAM Panel updated the assessment of the risks for human health related to the presence of 3‐monochloropropane diol (3‐MCPD) and its fatty acid esters in food published in 2016 in view of the scientific divergence identified in the establishment of the tolerable daily intake (TDI) in the Joint FAO/WHO Expert Committee on Food Additives and Contaminants (FAO/WHO) report published in 2017. …”
Publicado 2018
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1025“…Mechanistically, HCP5 sequestered miR-3619-5p and upregulated PPARG coactivator 1 alpha (PPARGC1A), increasing transcription complex Peroxisome proliferator activated receptor (PPAR) coactivator‐1α (PGC1α)/CEBPB and transcriptionally inducing carnitine palmitoyltransferase 1 (CPT1), which prompted the fatty acid oxidation (FAO) in GC cells. In conclusion, MSC-induced lncRNA HCP5 drove FAO through miR-3619-5p/AMPK/PGC1α/CEBPB axis to promote stemness and chemo-resistance of GC, indicating that targeting HCP5 was a novel approach to enhancing the efficacy of chemotherapy in GC.…”
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1026Egg Quality from Siciliana and Livorno Italian Autochthonous Chicken Breeds Reared in Organic Systempor Di Rosa, Ambra R., Chiofalo, Biagina, Lo Presti, Vittorio, Chiofalo, Vincenzo, Liotta, Luigi“…According to the Food and Agriculture Organization FAO objective for native breed safeguarding, the aim of this study was to present a first contribution on the egg quality of endangered the Siciliana chicken breed comparing these results with those of Livorno pure breed, reared in the same organic condition system to obtain useful data for future conservation programs. …”
Publicado 2020
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1027por Nguyen, Trang, Shu, Chang, Shang, Enyuan, Mela, Angeliki, Humala, Nelson, Mahajan, Aayushi, Akman, Hasan, Quinzii, Catarina, Zhang, Guoan, Westhof, Mike-Andrew, Karpel-Massler, Georg, Bruce, Jeffrey, Canoll, Peter, Siegelin, Markus“…Combining alisertib with inhibitors of FAO or the electron transport chain exerted substantial synergistic growth inhibition in PDX lines in vitro and extension of overall survival in orthotopic GBM PDX models without induction of toxicity in normal tissue. …”
Publicado 2021
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1028“…BACKGROUND: The Food Insecurity Experience Scale (FIES) is a UN FAO Voices of the Hungry (FAO-VoH) experiential metric of food insecurity (FI). …”
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1029“…RESEARCH DESIGN AND METHODS: In this ecological study, based on 192 countries, data on per capita sugar consumption were obtained from the Food and Agriculture Organization of the United Nations (FAO), on BMI from the World Health Organization and on diabetes prevalence from the International Diabetes Federation. …”
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1030por Cashman, Kevin D.“…In the present work, FAO national FBSs (from 2004 to 2017) for 173 to 178 countries around the globe were used to generate such average per capita vitamin D supply estimates. …”
Publicado 2021
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1031por Manomohan, Vandana, Ramasamy, Saravanan, Pichler, Rudolf, Nagarajan, Murali, Karuppusamy, Sivakumar, Krovvidi, Sudhakar, Nachiappan, Raja K., Peters, Sunday O., Periasamy, Kathiravan“…A total of 293 cattle from eight indigenous breeds were genotyped at 27 FAO/ISAG-recommended microsatellite marker loci. …”
Publicado 2022
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1032por Wu, Changqing, Dai, Chaoliu, Li, Xinyu, Sun, Mingju, Chu, Hongwei, Xuan, Qiuhui, Yin, Yalei, Fang, Chengnan, Yang, Fan, Jiang, Zhonghao, Lv, Qing, He, Keqing, Qu, Yiying, Zhao, Baofeng, Cai, Ke, Zhang, Shuijun, Sun, Ran, Xu, Guowang, Zhang, Lihua, Sun, Siyu, Liu, Yang“…Results: We found that long-term sorafenib treatment impairs fatty acid oxidation (FAO), leading to LD accumulation in HCC cells. Using multi-omics analysis in cultured HCC cells, we identified that aldo-keto reductase AKR1C3 is responsible for LD accumulation in HCC. …”
Publicado 2022
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1033por de la Rocque, Stephane, Errecaborde, Kaylee Marie Myhre, Belot, Guillaume, Brand, Tianna, Shadomy, Sean, von Dobschuetz, Sophie, Aguanno, Ryan, Carron, Maud, Caya, Francois, Ding, Shanlong, Dhingra, Madhur, Donachie, Daniel, Gongal, Gyanendra, Hoejskov, Peter, Ismayilova, Gunel, Lamielle, Gael, Mahrous, Heba, Marrana, Mariana, Nzietchueng, Serge, Oh, Yooni, Pinto, Julio, Roche, Xavier, Riviere-Cinnamond, Ana, Rojo, Cristina, Scheuermann, Lisa, Sinclair, Julie, Song, Junxia, Skrypnyk, Artem, Traore, Tieble, Wongsathapornchai, Kachen“…The Tripartite organisations—the Food and Agriculture Organization of the United Nations (FAO), the World Health Organization (WHO), and the World Organisation for Animal Health (WOAH)—have been collaborating for over two decades. …”
Publicado 2023
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1034“…Average intakes of lead, cadmium, and mercury are below the WHO/FAO tolerable intakes for adults; such tolerable intakes have not been established for arsenic and selenium. …”
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1035“…The title compound (ethyl vanillin), C(9)H(10)O(3), an important food additive and flavouring agent approved by FAO/WHO, has a vanilla odor four times that of vanillin and shows antimutagenic activity. …”
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1036por Parida, Satya, Muniraju, Murali, Altan, Eda, Baazizi, Ratiba, Raj, Gopal Dhinakar, Mahapatra, Mana“…Following the successful eradication of RPV, PPR has been targeted by the OIE and FAO as the next viral pathogen to be eradicated by 2030. …”
Publicado 2016
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1037por Tocco, Graziella, Zedda, Gloria, Casu, Mariano, Simbula, Gabriella, Begala, Michela“…The effect of some selected 3,3′- and 1,3′-diindolyl methane derivatives on cell proliferation of the hepatoma cell line FaO was also evaluated.…”
Publicado 2017
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1038“…The data was collected by the authors from FAO bioenergy and food security rapid appraisal tool (excel-based tools) that uses crop yields and production with 10 years (2005–2014) average annual production to estimate the residue yield (t/ha), by feedstock.…”
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1039“…In 2015, a global call for action was made by the WHO, OIE, FAO, and GARC to join forces toward the elimination of dog-transmitted human rabies by the year 2030. …”
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1040“…The indicators were built from mostly public data, including for example the CORINE Land Cover map, the GSP-FAO soil carbon stock map, and MODIS NDVI and ASTER DEM satellite images.…”
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