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  1. 2461
    “…The scRNA-seq reanalysis confirmed POU2F3-expressing epithelial cells (3.3% of all epithelial cells) and the 17% that co-expressed the other two tuft cell-related markers (SOX9/AVIL or SOX9/GFI1B), which suggested they were bona fide tuft cells. Of note, SOX9 is also known as the “master regulator” of TNBCs. …”
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    An exploratory study for tuft cells in the breast and their relevance in triple-negative breast cancer: the possible relationship of SOX9
  2. 2462
    por Galluzzi, L, Bravo-San Pedro, J M, Vitale, I, Aaronson, S A, Abrams, J M, Adam, D, Alnemri, E S, Altucci, L, Andrews, D, Annicchiarico-Petruzzelli, M, Baehrecke, E H, Bazan, N G, Bertrand, M J, Bianchi, K, Blagosklonny, M V, Blomgren, K, Borner, C, Bredesen, D E, Brenner, C, Campanella, M, Candi, E, Cecconi, F, Chan, F K, Chandel, N S, Cheng, E H, Chipuk, J E, Cidlowski, J A, Ciechanover, A, Dawson, T M, Dawson, V L, De Laurenzi, V, De Maria, R, Debatin, K-M, Di Daniele, N, Dixit, V M, Dynlacht, B D, El-Deiry, W S, Fimia, G M, Flavell, R A, Fulda, S, Garrido, C, Gougeon, M-L, Green, D R, Gronemeyer, H, Hajnoczky, G, Hardwick, J M, Hengartner, M O, Ichijo, H, Joseph, B, Jost, P J, Kaufmann, T, Kepp, O, Klionsky, D J, Knight, R A, Kumar, S, Lemasters, J J, Levine, B, Linkermann, A, Lipton, S A, Lockshin, R A, López-Otín, C, Lugli, E, Madeo, F, Malorni, W, Marine, J-C, Martin, S J, Martinou, J-C, Medema, J P, Meier, P, Melino, S, Mizushima, N, Moll, U, Muñoz-Pinedo, C, Nuñez, G, Oberst, A, Panaretakis, T, Penninger, J M, Peter, M E, Piacentini, M, Pinton, P, Prehn, J H, Puthalakath, H, Rabinovich, G A, Ravichandran, K S, Rizzuto, R, Rodrigues, C M, Rubinsztein, D C, Rudel, T, Shi, Y, Simon, H-U, Stockwell, B R, Szabadkai, G, Tait, S W, Tang, H L, Tavernarakis, N, Tsujimoto, Y, Vanden Berghe, T, Vandenabeele, P, Villunger, A, Wagner, E F, Walczak, H, White, E, Wood, W G, Yuan, J, Zakeri, Z, Zhivotovsky, B, Melino, G, Kroemer, G
    Publicado 2015
    “…Nonetheless, efficiently inhibiting the processes that are commonly thought to cause RCD, such as the activation of executioner caspases in the course of apoptosis, does not exert true cytoprotective effects in the mammalian system, but simply alters the kinetics of cellular demise as it shifts its morphologic and biochemical correlates. Conversely, bona fide cytoprotection can be achieved by inhibiting the transduction of lethal signals in the early phases of the process, when adaptive responses are still operational. …”
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    Essential versus accessory aspects of cell death: recommendations of the NCCD 2015
  3. 2463
    por Liao, Ruiqi, Mizzen, Craig A.
    Publicado 2017
    “…These data suggest that H1.4-S187 is a bona fide substrate for CDK9, a notion that is further supported by the significant colocalization of CDK9 and pS187-H1.4 to gene promoters in reciprocal re-ChIP analyses. …”
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    Site-specific regulation of histone H1 phosphorylation in pluripotent cell differentiation
  4. 2464
    “…Previous reports have indicated that while SMARCB1 lacks a bona fide nuclear localization signal, it harbors a masked nuclear export signal (NES) and that truncation of the C-terminal region results in unmasking of this NES leading to cytoplasmic localization. …”
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    Inhibition of nuclear export restores nuclear localization and residual tumor suppressor function of truncated SMARCB1/INI1 protein in a molecular subset of atypical teratoid/rhabdoid tumors
  5. 2465
    “…We determined that TRPM1 is a bona fide HSP90 client and characterized that AUY922 may reduce TRPM1 expression by disrupting the CDC37-HSP90 chaperone complex. …”
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    AUY922 induces retinal toxicity through attenuating TRPM1
  6. 2466
    “…Morphological, electrophysiological and gene expression analyses were performed on these neurons. RESULTS: Bona fide induced pluripotent stem cells and derived neurons could be generated in all cases. …”
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    A familiar study on self-limited childhood epilepsy patients using hIPSC-derived neurons shows a bias towards immaturity at the morphological, electrophysiological and gene expression levels
  7. 2467
    “…CONCLUSIONS: Our findings indicate that circFBXO7 acts as a bone fide tumor suppressor in ovarian cancer and that the circFBXO7/miR-96-5p/MTSS1 axis is an important regulator in the Wnt/β-catenin signaling pathway which may provide a promising target for ovarian cancer therapy. …”
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    circFBXO7/miR-96-5p/MTSS1 axis is an important regulator in the Wnt signaling pathway in ovarian cancer
  8. 2468
    “…T-cells in ganglia contribute to long-term control of latent HSV-1 infection, but it is unclear whether these cells are bona fide tissue-resident memory T-cells (T(RM)). We optimized the processing of human post-mortem nervous tissue to accurately phenotype T-cells in human TG ex vivo and in situ. …”
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    T-cells in human trigeminal ganglia express canonical tissue-resident memory T-cell markers
  9. 2469
    “…Despite these general conclusions from studies involving non-athletes, our primary conclusion is that substantial effort and research is still required to quantify the effects of bed rest on physical performance, identify effective countermeasures, and provide return-to-sport timelines in bona fide athletes. TRIAL REGISTRATION NUMBER AND DATE OF REGISTRATION: Registration ID: osf.io/d3aew; Date: October 24, 2022. …”
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    Effects of Bed Rest on Physical Performance in Athletes: A Systematic and Narrative Review
  10. 2470
    “…RESULTS: High levels of glycolysis-related metabolites and genes were present in HCCs with low miR-192-5p and CSC-positive HCCs in two independent HCC cohorts. miR-192-5p knockout cells displayed CSC features and miR-192-5p loss led to an enhanced glycolytic phenotype via upregulating three bona fide targets, GLUT1 and PFKFB3 (two glycolytic enzymes) and c-Myc (regulating glycolytic genes’ expression). …”
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    Loss of miR-192-5p initiates a hyperglycolysis and stemness positive feedback in hepatocellular carcinoma
  11. 2471
    “…We wanted to find out to what extent human SC-beta cells are suitable as an experimental cellular model and, with regard to a possible therapeutic use, whether SC-beta cells have a comparable vulnerability to cytokines as bona fide beta cells. METHODS: hPSCs were differentiated towards pancreatic organoids (SC-organoids) using a 3D production protocol. …”
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    Proinflammatory cytokines induce rapid, NO-independent apoptosis, expression of chemotactic mediators and interleukin-32 secretion in human pluripotent stem cell-derived beta cells
  12. 2472
    por Gould, Morton, 1913-
    Publicado 1993
    Tabla de Contenidos: “…The Stars and stripes forever (3:31) -- Parade (for percussion) (2:08) -- On parade (2:42) -- Semper fidelis (3:06) -- Jubilee (2:32) -- Fourth of July (2:23) -- Hands across the sea (1:40) -- Battle hymn (3:23) (based on Battle hymn of the republic / Steffe) -- National emblem (2:03) -- On the Mall (3:07) -- The thunderer (2:11) -- American youth march (2:24) -- The chimes of liberty (2:32) -- Happy go lucky (2:15) -- Washington post (2:26) -- The gladiator (2:02) -- El capitan (2:15) -- The U.S. field artillery march (2:29) -- Dixie (2:44) -- The high school cadets (1:52) -- Sound off (2:12) --The corcoran cadets march (2:23) -- American patrol (2:39) -- Yankee Doodle (2:40) -- Manhattan Beach (2:09) -- National fencibles march (2:32).…”
    CD Audiom
    Brass and percussion
  13. 2473
    Publicado 1993
    Tabla de Contenidos: “…Christus factus est (3:55) ; Crux fidelis (4:42) ; Vexilla regis (3:36) -- In Die Resurrectionis. …”
    CD Audiom
    Salve festa dies Gregorian chant for seasons of the year.
  14. 2474
    Publicado 2003
    Tabla de Contenidos: “…Rimui, Kajuju Kaburu, and Barrack O. Okoba -- Tanzania / Fidelis Kaihura, Edward Kaitaba, Edina Kahembe, and Charles Ngilorit -- China / Zhiling Dao, Huijun Guo, Aiguo Chen, and Yongneng Fu -- Papua New Guinea / John Sowei and Bryant Allen -- Peru / Miguel Pinedo-Vasquez, Pilar Paredes del Aguila, Roberto Romero, Michelle Rios, and Mario Pinedo-Panduro -- Mexico / Octavio Castelán-Ortega, Carlos González Esquival, Carlos Arriaga Jordán, and Cristina Chávez Mejia -- Jamaica / Elizabeth Thomas-Hope and Balfour Spence -- Thailand / Kanok Rerkasem -- Findings from the PLEC project / Harold Brookfield, Helen Parsons, and Muriel Brookfield.…”
    Libro
    Agrodiversity : learning from farmers across the world /
  15. 2475
    Publicado 2014
    Tabla de Contenidos: “…24° Studio -- Adriane Colburn -- Alexander Korzer-Robinson -- Alice von Maltzahn -- Andrée-Anne Dupuis Bourret -- Andy Singleton -- Anne ten Donkelaar -- Aritonius Bui -- Art des Hauses -- Aaya Kozina -- Bea Szenfeld -- Bovery Lee -- Cara Barer -- Caroline Jane Harris -- Cecilia Levy -- Charles Clary -- Charlotte McGowan-Griffin -- Chishen Chiu -- Christine Kim -- Marcin Kedzior -- Claire Brewster -- Clare Pentlow -- Cybéle Young -- Dagna Napierala -- Daniele Papuli -- Elonah O'Neil Reid -- Elsa Mora -- Fideli Sundqvist -- Flora Vagi -- Géraldine Gonzalez -- Harikrishnan Panicker -- Haruhiko Tanaka -- Hattie Newman -- Hiroko Matsushita -- Jeff Nishinaka -- Jun Mitani -- Karen Margolis -- Katsumi Hayakawa -- Kelli Anderson -- Kerry Miller -- Krona & Lion -- Kuin Heuff -- Laura García Serventi -- Lauren Kussro -- Lee Huey Ming -- Liz Shreeve -- Lucie Houdková -- Lydia Hirte -- Madeline Silcock -- Mademoiselle Maurice -- Marine Coutroutsios -- Mathilde Nivet -- Mathilde Roussel -- Matthew Picton -- Maud Vantours -- Mia Pearlman -- Mia Wen-Hsuan Liu -- Michael Velliquette -- Michelle Muzyka -- Nathalie Boutté -- Noa Haim -- Ohashi Shinobu -- Oksana Valentelis -- Pablo Lehman -- Paige Smith -- Paper-Cut-Project -- Pascale Malilo -- Pilar Mackenna -- Rachael Ashe -- Rachel Thomas -- Rogan Brown -- Sachin George Sebastian -- Sarah Dennis -- Sarah Kate Burgess -- Sarah Kelly -- Sixstation -- Stephanie Beck -- Super Nature -- Sushima Serigara -- Takashi Kuribayashi -- Terada Mokei -- The Makerie Studio -- Tine DE Ruysser -- Torafu Architect's -- Utopia & Utility -- Wendy Wallin Malinow -- Wirin Chaowana -- Yuko Nishimura -- Zin&Zum.…”
    Libro
    Paper play
  16. 2476
    “…Preliminary observations show species level host specificity for Conopea fidelis sp. n.…”
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    Two new species of the gorgonian inhabiting barnacle, Conopea (Crustacea, Cirripedia, Thoracica), from the Gulf of Guinea
  17. 2477
    por Frégault, Guy
    Publicado 1969
    Libro
    La civilisation de la Nouvelle-France, 1713-1744 /
  18. 2478
    “…Although only partial profiles were obtained, the data were sufficient for kinship analysis with the profile of a paternal niece of Sister Marija (Fides Kozulić). The data indicate that it is 574,195-fold more likely that the two sets of skeletal remains represent 2nd-degree relatives of Fides than sisters who are unrelated to Fides. …”
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    A Forensic Genomics Approach for the Identification of Sister Marija Crucifiksa Kozulić
  19. 2479
    por Guévremont, Germaine
    Publicado 1980
    Libro
    Marie-Didace : roman /
  20. 2480
    “…Here we report the cultivation and characterization of a novel strain of Shewanella fidelis from the gut of the marine tunicate Ciona intestinalis, inducible prophages from the S. fidelis genome, and a strain-specific lytic phage recovered from surrounding seawater. …”
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    Isolation and Characterization of a Shewanella Phage–Host System from the Gut of the Tunicate, Ciona intestinalis
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