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Mostrando 481 - 500 Resultados de 2,933 Para Buscar '"FIDE"', tiempo de consulta: 0.27s Limitar resultados
  1. 481
    “…Finally, we use differential expression analysis to determine which are up-regulated in serrate-1 compared to wild type, to select the best candidates for bona fide pri-miRNAs expressed in the globular stage embryos. …”
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    Annotating and quantifying pri-miRNA transcripts using RNA-Seq data of wild type and serrate-1 globular stage embryos of Arabidopsis thaliana
  2. 482
    “…Further investigation demonstrated that lncRNA-LET was a bona fide target gene of DANCR. In addition, high DANCR and low lncRNA-LET were significantly correlated with lymph node metastasis and late clinical stage. …”
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    LncRNA DANCR promotes migration and invasion through suppression of lncRNA-LET in gastric cancer cells
  3. 483
    “…Three genes annotated to affect translation or posttranslational modifications were validated as bona fide longevity genes by mutagenesis and complementation experiments. …”
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    Molecular Basis of Bacterial Longevity
  4. 484
    por Dorhoi, Anca, Du Plessis, Nelita
    Publicado 2018
    “…Monocytic MRC, also termed monocytic myeloid-derived suppressor cells (M-MDSC), are bona fide phagocytes, capable of pathogen internalization and persistence, while exerting localized suppressive activity. …”
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    Monocytic Myeloid-Derived Suppressor Cells in Chronic Infections
  5. 485
    “…A few lipids act as bona fide second messengers by binding to specific sites that control channel and transporter gating. …”
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    Lipid signaling to membrane proteins: From second messengers to membrane domains and adapter-free endocytosis
  6. 486
    por Bresson, Stefan, Tollervey, David
    Publicado 2018
    “…Here we describe how bona fide transcripts are specifically protected, particularly by 5′ and 3′ modifications. …”
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    Surveillance-ready transcription: nuclear RNA decay as a default fate
  7. 487
    “…A gene which carries a bona fide loss-of-function mutation effectively becomes a functionless pseudogene, free from selective constraint. …”
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    Are Nonsense Alleles of Drosophila melanogaster Genes under Any Selection?
  8. 488
    “…Stress granule assembly alone is sufficient to decrease the number of senescent cells without affecting the expression of bona fide senescence markers. SG‐mediated inhibition of senescence is associated with the recruitment of the plasminogen activator inhibitor‐1 (PAI‐1), a known promoter of senescence, to these entities. …”
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    Stress granules counteract senescence by sequestration of PAI‐1
  9. 489
    “…Both glial cell line-derived neurotrophic factor (GDNF) and fibroblast growth factor 2 (FGF2) are bona fide self-renewal factors for spermatogonial stem cells, whereas retinoic acid (RA) induces spermatogonial differentiation. …”
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    FGF2 Has Distinct Molecular Functions from GDNF in the Mouse Germline Niche
  10. 490
    “…Dehydrogenases react with electron transfer flavoproteins as terminal electron acceptors and do not show a considerable reactivity with dioxygen, whereas dioxygen serves as a bona fide substrate for oxidases. We recently engineered (2S)-methylsuccinyl-CoA dehydrogenase towards oxidase activity by rational mutagenesis. …”
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    Molecular Basis for Converting (2S)-Methylsuccinyl-CoA Dehydrogenase into an Oxidase
  11. 491
    “…Among these genes, NKX2-2 is a bona fide tumor suppressor for osteosarcoma. Overexpression of NKX2-2 decreases the migration, invasion, proliferation and colony formation of osteosarcoma cells in vitro and suppresses tumor growth and metastasis in vivo. …”
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    NKX2-2 Suppresses Osteosarcoma Metastasis and Proliferation by Downregulating Multiple Target Genes
  12. 492
    “…Here, we characterize PPP1R35 as a novel bona fide centrosomal protein and demonstrate that it is critical for centriole elongation. …”
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    PPP1R35 is a novel centrosomal protein that regulates centriole length in concert with the microcephaly protein RTTN
  13. 493
    por Nakayama, Yuji, Inoue, Toshiaki
    Publicado 2016
    “…The ultimate goal of both the microtubule poisons-based cancer therapies involves the induction of a mechanism defined as mitotic catastrophe, which is a bona fide intrinsic oncosuppressive mechanism that senses mitotic failure and responds by driving a cell to an irreversible antiproliferative fate of death or senescence. …”
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    Antiproliferative Fate of the Tetraploid Formed after Mitotic Slippage and Its Promotion; A Novel Target for Cancer Therapy Based on Microtubule Poisons
  14. 494
    por Trievel, Raymond C., Scheiner, Steve
    Publicado 2018
    “…Quantum mechanical analyses of a representative subset of the methyltransferase structures from the survey revealed that the calculated interaction energies and spectral properties are consistent with the values for bona fide carbon tetrel bonds. The discovery of methyl tetrel bonding offers new insights into the mechanism underlying the S(N)2 reaction catalyzed by AdoMet-dependent methyltransferases. …”
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    Crystallographic and Computational Characterization of Methyl Tetrel Bonding in S-Adenosylmethionine-Dependent Methyltransferases
  15. 495
    “…Cardiac complications include an increased risk of myocardial infarction, myocarditis and dilated cardiomyopathy, valve disease, endothelial dysfunction, excessive fibrosis, and bona fide autoimmune-mediated tissue damage by autoantibodies or auto-reactive cells. …”
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    Cardiac phenotype in mouse models of systemic autoimmunity
  16. 496
    “…Adipose tissue is critical to whole-body energy metabolism and has become recognized as a bona fide endocrine organ rather than an inert lipid reservoir. …”
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    Targeting White Adipose Tissue with Exercise or Bariatric Surgery as Therapeutic Strategies in Obesity
  17. 497
    “…The clinical value of silibinin as a bona fide anti-cancer therapy, however, remains uncertain with respect to its bioavailability and blood–brain barrier (BBB) permeability. …”
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    Intestinal Permeability Study of Clinically Relevant Formulations of Silibinin in Caco-2 Cell Monolayers
  18. 498
    “…To demonstrate the potency of the decoy screening methodology to overcome redundancy and identify bona fide clock regulators, we performed follow-up studies on MAC3A (PUB59) and MAC3B (PUB60). …”
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    Decoys provide a scalable platform for the identification of plant E3 ubiquitin ligases that regulate circadian function
  19. 499
    “…This case adds to the limited number of case reports describing Paenibacillus species infection in healthy adults and presents a unique case of bona fide P. macerans infection requiring life-long antibiotic therapy.…”
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    Recurrent Paenibacillus infection
  20. 500
    “…Here we show PTEX is a bona fide translocon by determining near-atomic resolution cryoEM structures of the endogenous PTEX core complex of EXP2, PTEX150 and HSP101, isolated from Plasmodium falciparum in the engaged and resetting states of endogenous cargo translocation with CRISPR/Cas9-engineered epitope tags. …”
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    Malaria Parasite Translocon Structure and Mechanism of Effector Export
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