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Mostrando 781 - 800 Resultados de 2,933 Para Buscar '"FIDE"', tiempo de consulta: 0.21s Limitar resultados
  1. 781
    “…In this study we have provided detailed evidence demonstrating that mammalian cells possess a bona fide DNA methylation recovery system. We have also shown that DNA methylation recovery was mediated by the major human DNA methyltransferase, DNMT1. …”
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    Transcriptional Repressive H3K9 and H3K27 Methylations Contribute to DNMT1-Mediated DNA Methylation Recovery
  2. 782
    “…Thus, CD14(dim) cells are bona fide monocytes involved in the innate local surveillance of tissues and the pathogenesis of autoimmune diseases.…”
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    Human CD14(dim) Monocytes Patrol and Sense Nucleic Acids and Viruses via TLR7 and TLR8 Receptors
  3. 783
    “…Its 3′-part contains a decoy 5′-splice site (ss), which inhibits splicing at the bona fide 5′-ss. Only the 3D structure of a small NRS fragment had been experimentally studied. …”
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    Structural and functional analysis of the Rous Sarcoma virus negative regulator of splicing and demonstration of its activation by the 9G8 SR protein
  4. 784
    “…Cellular miRNA signatures in cohorts of normal individuals are catalogued and the abundance and gender specific expression of bona fide circulating markers explored after calibrating the signal for this interfering class. …”
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    Impact of Cellular miRNAs on Circulating miRNA Biomarker Signatures
  5. 785
    “…Using the subtelomeric ZRT1 and FIT3 genes activated in response to zinc and iron deficiency, respectively, we show that transcription of these CD-CUTs mediates repression at the bona fide promoters, by preventing premature binding of RNA polymerase II in conditions of metal repletion. …”
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    Cryptic Transcription Mediates Repression of Subtelomeric Metal Homeostasis Genes
  6. 786
    “…Here, we first show using deletion analysis and in vivo infection, that InlK is a bona fide virulence factor, poorly expressed in vitro and well expressed in vivo, and that it is anchored to the bacterial surface by sortase A. …”
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    Recruitment of the Major Vault Protein by InlK: A Listeria monocytogenes Strategy to Avoid Autophagy
  7. 787
    “…In this regard, introduction of constitutively activated IKKβ (IKKβ(SSEE)) but not wild-type IKKβ into monocytes stimulates differentiation of bona fide osteoclasts in the absence of RANK ligand (RANKL). …”
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    IKKβ Activation Is Sufficient for RANK-Independent Osteoclast Differentiation and Osteolysis
  8. 788
    “…One of these genes, the conserved thermoreceptor TrpA1, was confirmed as a bona fide “pain” gene in both adult and larval fly nociception paradigms. …”
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    TrpA1 Regulates Thermal Nociception in Drosophila
  9. 789
    “…We further validated dynamin 2/NPRAP colocalization and direct interaction in vivo, confirming their bona fide partnership. Interestingly, dynamin 2 has established roles in endocytosis and actin assembly, and both of these processes have the potential to interface with the cell adhesion and intracellular signaling processes that involve NPRAP. …”
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    Identification of Novel NPRAP/δ-Catenin-Interacting Proteins and the Direct Association of NPRAP with Dynamin 2
  10. 790
    “…These data establish that lipoglycans are bona fide Microbe-Associated Molecular Patterns contributing to innate immune detection of mycobacteria, via TLR2 among other PRRs.…”
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    Lipoglycans Contribute to Innate Immune Detection of Mycobacteria
  11. 791
    “…Due to the presence of pseudogenes, however, each haplotype encodes only one to three bona fide DRB transcripts. Depending on the region configuration in which the Mafa-DRB gene is embedded, identical alleles may display differential transcription levels. …”
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    DR haplotype diversity of the cynomolgus macaque as defined by its transcriptome
  12. 792
    “…Bioinformatics analysis, gel shift assay, and chromatin immunoprecipitation demonstrate that the RIP140 promoter contains bona fide E2F response elements. In transiently transfected MCF-7 breast cancer cells, the RIP140 promoter is transactivated by overexpression of E2F1/DP1. …”
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    The RIP140 Gene Is a Transcriptional Target of E2F1
  13. 793
    “…MOAP-1 is part of the Ras association domain family 1A (RASSF1A)/MOAP-1 pro-apoptotic extrinsic signaling pathway that regulates apoptosis by utilizing death receptors such as tumor necrosis factor α (TNFα) or TNF-related apoptosis-inducing ligand (TRAIL) to inhibit abnormal growth. RASSF1A is a bona fide tumor suppressor gene that is epigenetically silenced by promoter-specific methylation in numerous human cancers. …”
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    Modulator of Apoptosis 1: A Highly Regulated RASSF1A-Interacting BH3-Like Protein
  14. 794
    “…We have validated our approach on 15 co-expressed gene sets, 21 ChIP data sets, 628 curated gene sets and multiple individual case studies, and show that meaningful regulatory features can be confidently discovered; that bona fide enhancers can be identified, both by in vivo events and by TF motifs; and that combinations of in vivo events and TF motifs further increase the performance of enhancer prediction.…”
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    i-cisTarget: an integrative genomics method for the prediction of regulatory features and cis-regulatory modules
  15. 795
    “…Our approach overcomes a major challenge in the muscular dystrophy field of rapidly and consistently identifying bona fide dystrophin-interacting proteins in tissues. …”
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    Proteomic Analysis Reveals New Cardiac-Specific Dystrophin-Associated Proteins
  16. 796
    “…Our data suggest that bona fide monomeric fluorescent protein tags have less impact on proper assembly of HSV1 capsids and nuclear capsid egress than tags that tend to dimerize. …”
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    Improper Tagging of the Non-Essential Small Capsid Protein VP26 Impairs Nuclear Capsid Egress of Herpes Simplex Virus
  17. 797
    por Hong, Mingi, Krauss, Robert S.
    Publicado 2012
    “…We report here a mouse model in which there is dramatic synergy between mutation of a bona fide HPE gene (Cdon, which encodes a SHH co-receptor) and a suspected HPE teratogen, ethanol. …”
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    Cdon Mutation and Fetal Ethanol Exposure Synergize to Produce Midline Signaling Defects and Holoprosencephaly Spectrum Disorders in Mice
  18. 798
    “…The occurrence and distribution of bona fide type II calcium binding sites within the four annexin domains were found to be different in each of these groups. …”
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    Genome-wide Comparative Analysis of Annexin Superfamily in Plants
  19. 799
    “…CONCLUSION: We confirm that Cadm1 is indeed a bona fide tumor suppressor gene and provide new insights into genetic partners that co-operate in tumorigenesis when Cadm1-expression is lost.…”
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    Increased tumorigenesis associated with loss of the tumor suppressor gene Cadm1
  20. 800
    por Wolf, Yuri I., Koonin, Eugene V.
    Publicado 2012
    “…To test this “BBH-orthology conjecture,” we take advantage of the operon organization of bacterial and archaeal genomes and assume that, when two genes in compared genomes are flanked by two BBH show statistically significant sequence similarity to one another, these genes are bona fide orthologs. Under this assumption, we tested whether middle genes in “syntenic orthologous gene triplets” form BBH. …”
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    A Tight Link between Orthologs and Bidirectional Best Hits in Bacterial and Archaeal Genomes
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