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Mostrando 901 - 920 Resultados de 2,933 Para Buscar '"FIDE"', tiempo de consulta: 0.14s Limitar resultados
  1. 901
    “…Despite decades of technical and theoretical advances, distinguishing bona fide information content from the multiple sources of synaptic variability remains a challenging problem. …”
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    Parsing Out the Variability of Transmission at Central Synapses Using Optical Quantal Analysis
  2. 902
    “…Despite the relevance of CD39/CD73 to bone health, the roles of these enzymes in bona fide skeletal disorders remain unknown. We demonstrate that CD39/CD73 expression and extracellular adenosine levels in the bone marrow are substantially decreased in animals with osteoporotic bone loss. …”
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    Dysregulation of ectonucleotidase-mediated extracellular adenosine during postmenopausal bone loss
  3. 903
    por Han, Heonjong, Lee, Sangyoung, Lee, Insuk
    Publicado 2019
    “…GSEA may be suboptimal for functional gene sets; however, because DEGs from the expression dataset may not be functional genes per se but dysregulated genes perturbed by bona fide functional genes. To overcome this shortcoming, we developed network-based GSEA (NGSEA), which measures the enrichment score of functional gene sets using the expression difference of not only individual genes but also their neighbors in the functional network. …”
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    NGSEA: Network-Based Gene Set Enrichment Analysis for Interpreting Gene Expression Phenotypes with Functional Gene Sets
  4. 904
    “…We verified their bona fide circular topology using circular DNA deep-sequencing, 2D gel electrophoresis and inverse polymerase chain reaction. …”
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    Programmed genome rearrangements in Oxytricha produce transcriptionally active extrachromosomal circular DNA
  5. 905
    “…Human induced pluripotent stem cells (iPSCs) can be differentiated in vitro into bona fide cardiomyocytes for disease modelling and personalized medicine. …”
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    Mitochondrial Fusion by M1 Promotes Embryoid Body Cardiac Differentiation of Human Pluripotent Stem Cells
  6. 906
    “…Several commensal and pathogenic Gram‐negative bacteria produce DNA‐damaging toxins that are considered bona fide carcinogenic agents. The microbiota of colorectal cancer (CRC) patients is enriched in genotoxin‐producing bacteria, but their role in the pathogenesis of CRC is poorly understood. …”
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    Infection with genotoxin‐producing Salmonella enterica synergises with loss of the tumour suppressor APC in promoting genomic instability via the PI3K pathway in colonic epithelial cells
  7. 907
    “…Using RNA affinity chromatography, we identified the tripartite motif-containing protein 25 (TRIM25) as a bona fide caspase-2 mRNA-binding protein in colon carcinoma cells. …”
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    Identification of TRIM25 as a Negative Regulator of Caspase-2 Expression Reveals a Novel Target for Sensitizing Colon Carcinoma Cells to Intrinsic Apoptosis
  8. 908
    “…These results support our conclusion that nsPEF induce ER stress, accompanied by bona fide ICD.…”
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    Nanosecond Pulsed Electric Fields Induce Endoplasmic Reticulum Stress Accompanied by Immunogenic Cell Death in Murine Models of Lymphoma and Colorectal Cancer
  9. 909
    por Rinkevich, Frank D.
    Publicado 2020
    “…The resistance ratios from in vitro amitraz bioassays were correlated with reduced Apivar(®) efficacy, demonstrating bona fide cases of Varroa control failures due to amitraz resistance. …”
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    Detection of amitraz resistance and reduced treatment efficacy in the Varroa Mite, Varroa destructor, within commercial beekeeping operations
  10. 910
    “…There has been an attempted paradigm shift within the last decade to think of transplanted stem cells as “medicinal” therapies that orchestrate healing on the basis of their secretome and immunomodulatory profiles rather than acting as bona fide stem cells that proliferate, differentiate, and directly produce matrix to form de novo tissues. …”
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    Recent advances toward understanding the role of transplanted stem cells in tissue-engineered regeneration of musculoskeletal tissues
  11. 911
    “…Here, we use single-cell transcriptomics, electron microscopy, whole-cell patch-clamp electrophysiology and calcium imaging to demonstrate that neuron-glioma interactions include electrochemical communication through bona fide AMPA receptor-dependent neuron-glioma synapses. …”
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    Electrical and synaptic integration of glioma into neural circuits
  12. 912
    “…This will allow us to better define states of bona fide tumor metabolism. We will further contextualize the stress response and the metabolic evolutionary trajectory seen in tumors, and how these contribute to tumor progression. …”
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    Adapt and conquer: Metabolic flexibility in cancer growth, invasion and evasion
  13. 913
    “…Loss of function of senataxin (SETX), a bona-fide RNA/DNA helicase, is associated with neuronal degeneration leading to Ataxia and Ocular Apraxia (AOA) in human patients. …”
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    Effects of senataxin and RNA exosome on B-cell chromosomal integrity
  14. 914
    por Tatsis, Nia, Ertl, Hildegund C.J.
    Publicado 2004
    “…Adenoviruses have transitioned from tools for gene replacement therapy to bona fide vaccine delivery vehicles. They are attractive vaccine vectors as they induce both innate and adaptive immune responses in mammalian hosts. …”
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    Adenoviruses as vaccine vectors
  15. 915
    por Land, Walter Gottlieb
    Publicado 2018
    “…One of these DAMPs, the major histocompatibility complex I-related molecule A, is shown to act as a bona fide transplantation antigen. In sum, the endogenous constitutively expressed native molecules represent an impressive category of DAMPs with extraordinary properties, which play a critical role in the pathogenesis of many human diseases.…”
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    Endogenous DAMPs, Category I: Constitutively Expressed, Native Molecules (Cat. I DAMPs)
  16. 916
    “…While this work shows new possibility of chemical–electricity coupling in SOFCs, it might also open bona fide avenues toward the electrocatalytic synthesis of chemicals at higher temperatures.…”
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    Generating C4 Alkenes in Solid Oxide Fuel Cells via Cofeeding H(2) and n-Butane Using a Selective Anode Electrocatalyst
  17. 917
    “…Although PLP is a bona fide myelin protein, the major hallmark of the disease in both SPG2 patients and mouse models are axonal swellings comprising accumulations of numerous organelles including mitochondria, gradually leading to irreversible axonal loss. …”
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    Pathology of myelinated axons in the PLP-deficient mouse model of spastic paraplegia type 2 revealed by volume imaging using focused ion beam-scanning electron microscopy
  18. 918
    “…We demonstrate that Hfq CLASH robustly captures bona fide RNA-RNA interactions. We identified hundreds of novel sRNA base-pairing interactions, including many sRNA-sRNA interactions and involving 3’UTR-derived sRNAs. …”
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    Hfq CLASH uncovers sRNA-target interaction networks linked to nutrient availability adaptation
  19. 919
    “…Single‐cell technologies allow measuring chromatin accessibility and gene expression in each cell, but jointly utilizing both layers to map bona fide gene regulatory networks and enhancers remains challenging. …”
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    Identification of genomic enhancers through spatial integration of single‐cell transcriptomics and epigenomics
  20. 920
    “…Altogether, our data indicate rafoxanide as a bona fide ICD inducer.…”
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    Rafoxanide Induces Immunogenic Death of Colorectal Cancer Cells
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