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Mostrando 161 - 180 Resultados de 2,933 Para Buscar '"FIDE"', tiempo de consulta: 0.30s Limitar resultados
  1. 161
    “…Through a variety of experimental approaches, our data prove that HEV-IRESl is a bona fide internal translation initiation site.…”
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    RNA-Protein Interactome at the Hepatitis E Virus Internal Ribosome Entry Site
  2. 162
    “…QPCR based validation of the corresponding mRNAs, in response to both UPF1 knockdown and cycloheximide treatment, identified 17 bona fide NMD targets. Most of these were associated with bioinformatically predicted NMD activating features, predominantly upstream open reading frames (uORFs). …”
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    Expression proteomics of UPF1 knockdown in HeLa cells reveals autoregulation of hnRNP A2/B1 mediated by alternative splicing resulting in nonsense-mediated mRNA decay
  3. 163
    “…BACKGROUND: The identification of bona fide microbial taxa in microbiomes derived from ancient and historical samples is complicated by the unavoidable mixture between DNA from ante- and post-mortem microbial colonizers. …”
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    Mining ancient microbiomes using selective enrichment of damaged DNA molecules
  4. 164
    “…Hydroxycitric acid (HCA) is considered a bona fide CRM since it depletes acetyl-CoA pools by acting as a competitive inhibitor of ATP citrate lyase (ACLY), ultimately repressing protein acetylation and promoting autophagy. …”
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    In S. cerevisiae hydroxycitric acid antagonizes chronological aging and apoptosis regardless of citrate lyase
  5. 165
    “…Of 62 patients with available clinical data, 12 (19%) had bona fide ATTR cardiac amyloidosis prior to/concomitant with the non‐cardiac site biopsy. …”
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    Non‐cardiac biopsy sites with high frequency of transthyretin amyloidosis
  6. 166
    “…We therefore discuss conditions and approaches promoting formation of bona fide bone and simple means for distinguishing it from the other cell‐ECM structures. …”
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    Bone Formation in 2D Culture of Primary Cells
  7. 167
    Publicado 2015
    “…In particular, no bona fide scientist will be excluded from participation on the grounds of national origin, nationality, or political considerations unrelated to science.…”
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    21st International Conference on Few-Body Problems in Physics
  8. 168
    “…Whilst Matrigel increases the rate of engraftment by MaSCs, it also appears to promote progenitor activity that is distinct from bona fide stem cell activity. This caveat should be considered when interpreting mammary reconstitution assays that incorporate Matrigel, particularly when transplanting high cell numbers.…”
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    Jekyll or Hyde: does Matrigel provide a more or less physiological environment in mammary repopulating assays?
  9. 169
    “…Several key genes have been identified, whose products can be considered to represent bone fide clock molecules. Furthermore it appears that the same genes are important in generating rhythmic behaviour in both insects and man. …”
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    Molecular chronobiology
  10. 170
    por Spits, C.
    Publicado 2012
    “…This fraudulent practice is far from the reality of scientists and bona fide companies. Much effort is put into addressing all the hurdles we have been encountering for the safe use of stem cells in therapy. …”
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    Stem cell therapy: facts and fiction
  11. 171
    “…Fractions were analyzed by western blotting for HIV-1 capsid content as well as for nuclear and cytosolic markers to assess the bona fide origin of the fractions. This protocol can be applied in both cycling and non-cycling human cells. …”
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    Biochemical detection of capsid in the nucleus during HIV-1 infection
  12. 172
    por Kalo, Eric, Read, Scott, Ahlenstiel, Golo
    Publicado 2022
    “…In this review, we explore emerging reprograming pathways that aim to generate bone fide insulin producing cells. We focus on small molecules and key transcriptional regulators that orchestrate phenotypic conversion and maintenance of engineered cells.…”
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    Reprogramming—Evolving Path to Functional Surrogate β-Cells
  13. 173
    “…The method utilizes label-free quantitative data and constructs separate distributions for true and false interactions to derive the probability of a bona fide protein-protein interaction. We demonstrate that SAINT is applicable to data of different scales and protein connectivity and allows for the transparent analysis of AP-MS data.…”
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    SAINT: Probabilistic Scoring of Affinity Purification - Mass Spectrometry Data
  14. 174
    por Grose, Julianne H., Rutter, Jared
    Publicado 2010
    “…In our current model for PAS kinase regulation, a small molecule metabolite binds the sensory PAS domain and activates the enzyme. Although bona fide PAS kinase substrates are scarce, in vitro substrate searches provide putative targets for exploration.…”
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    The Role of PAS Kinase in PASsing the Glucose Signal
  15. 175
    por Barton, Neil
    Publicado 2019
    “…On the one hand it is a bona fide cardinal number, yet on the other it is linked to ideas of nothingness and non-being. …”
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    Absence perception and the philosophy of zero
  16. 176
    “…SIMPLE SUMMARY: This study identified that Aurora kinase B (AurB), a cellular protein that is upregulated in human cancers, is a bona fide interacting partner of HPVE6. HPVE6 complexes with AurB at the C-terminus end of E6, upstream of the E6-PBM. …”
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    Interaction between Human Papillomavirus-Encoded E6 Protein and AurB Induces Cell Immortalization and Proliferation—A Potential Target of Intervention
  17. 177
    “…Unexpectedly, we found that only 22%–24% of the bona fide human ERα binding sites were overlapping conserved regions in whole genome vertebrate alignments, which suggest limited conservation of functional binding sites. …”
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    Whole-Genome Cartography of Estrogen Receptor α Binding Sites
  18. 178
    “…However, the prioritization of bona fide, reproducible genetic associations from GWAS results remains a central challenge in identifying genomic loci underlying common complex diseases. …”
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    e-GRASP: an integrated evolutionary and GRASP resource for exploring disease associations
  19. 179
    “…Most synthetic recombinant prion protein (rPrP) amyloids prepared without cofactors are non-infectious or much less infectious than bona fide tissue-derived PrP(Sc). This effect has been associated with differences in folding of the aggregates, manifested in part by reduced solvent exclusion and protease-resistance in rPrP amyloids, especially within residues ~90–160. …”
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    Role of the central lysine cluster and scrapie templating in the transmissibility of synthetic prion protein aggregates
  20. 180
    “…Consequently, PCSCs may become the predominant population in treatment-resistant tumors, and the “root cause” for drug resistance. microRNA-34a (miR-34a) is a bona fide tumor-suppressive miRNA, and its expression is dysregulated in PCa. …”
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    MicroRNA-34a, Prostate Cancer Stem Cells, and Therapeutic Development
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