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  1. 1861
    “…MSC-EVs induced CD24(hi)CD38(hi) B cells to a similar extent of that of MSC, but not bona fide Bregs since they did not produce IL-10. Our results show that B cell modulation by MSC is partially mediated by soluble factors other than EVs.…”
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    Immunomodulatory Effect of MSC on B Cells Is Independent of Secreted Extracellular Vesicles
  2. 1862
    “…This report defines latency IIb as a bona fide latency state independent from latency III and identifies biomarkers for understanding EBV-associated tumor heterogeneity.…”
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    Identification of Host Biomarkers of Epstein-Barr Virus Latency IIb and Latency III
  3. 1863
    “…CONCLUSION: Our study discloses that CFT is a bona fide benign fibroblastic lesion, regardless of its developing location. …”
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    Clinicopathologic Study of Calcifying Fibrous Tumor Emphasizing Different Anatomical Distribution and Favorable Prognosis
  4. 1864
    “…NIK represents a bona fide target of miR-122 whose transcription is downregulated by HCV through reduced HNF4A expression. …”
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    Hepatitis C Virus Infection Induces Hepatic Expression of NF-κB-Inducing Kinase and Lipogenesis by Downregulating miR-122
  5. 1865
    “…TgFBXO1 interacts with Toxoplasma SKP1 confirming it as a bona fide F-box protein. In interphase parasites, TgFBXO1 is a component of the Inner Membrane Complex (IMC), which is an organelle that underlies the plasma membrane. …”
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    Toxoplasma F-box protein 1 is required for daughter cell scaffold function during parasite replication
  6. 1866
    “…We identify RcsF and OmpA as bone fide interactors of BamA, and we show that MetQ association with the ABC transporter MetNI depends on its N-terminal lipid anchor. …”
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    Profiling the Escherichia coli membrane protein interactome captured in Peptidisc libraries
  7. 1867
    “…There was insufficient data to conduct a bona fide meta-analysis. Whether the apparent reduction in mortality may be attributed to the mitigation of catecholamine excess is unclear. …”
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    The association between premorbid beta blocker exposure and mortality in sepsis—a systematic review
  8. 1868
    “…Recent advances in whole exome sequencing (WES) have identified five new bona fide CH genes, implicating impaired regulation of neural stem cell fate in CH pathogenesis. …”
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    SLC12A ion transporter mutations in sporadic and familial human congenital hydrocephalus
  9. 1869
    por Epstein, Nancy E.
    Publicado 2019
    “…This 80+ year-old patient, without a neurological deficit or significant cervical CT-documented pathology, underwent 2 cervical ESI that unnecessarily exposed him to potential cardiac-stent related thrombosis (e.g. stopping ASA for 5 days-a bona-fide requirement for ESI to avoid acute epidural hematomas).…”
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    Unnecessary Cervical Epidural Injection in An Octogenarian
  10. 1870
    “…Subsequently, hippocampal Jdp2 was confirmed to be up‐regulated in a restraint stress model, posing Jdp2 as a bona fide MR target that is also responsive in an acute stress condition. …”
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    Identification of mineralocorticoid receptor target genes in the mouse hippocampus
  11. 1871
    “…Our structural and biochemical data together demonstrate that N6amt1 is a bona fide protein MTase rather than a DNA MTase.…”
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    Structural insight into human N6amt1–Trm112 complex functioning as a protein methyltransferase
  12. 1872
    “…This is a descriptive analysis and as such the conclusion that POU5F1(+) and SOX17(+) cells represent bona fide PGCs can only be considered as preliminary. …”
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    Human blastocyst outgrowths recapitulate primordial germ cell specification events
  13. 1873
    “…Unlike other animal models, horses spontaneously develop AF and could therefore serve as a bona fide model in AF research. We therefore aimed to study the electrical, functional and structural remodelling caused by chronic AF in a horse model. …”
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    Longitudinal study of electrical, functional and structural remodelling in an equine model of atrial fibrillation
  14. 1874
    “…Based on bioinformatic analysis and enzymatic assays, Fh3GT2 turned out to be another bona fide glycosyltransferase gene. Biochemical analysis further proved that Fh3GT2 preferentially glucosylated kaempferol while Fh3GT1 controlled the glucosylation of quercetin and anthocyanidins. …”
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    Functional Differentiation of Duplicated Flavonoid 3-O-Glycosyltransferases in the Flavonol and Anthocyanin Biosynthesis of Freesia hybrida
  15. 1875
    “…Thus, these data suggest that PilU is a bona fide retraction ATPase that supports pilus retraction in a PilT-dependent manner. …”
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    PilT and PilU are homohexameric ATPases that coordinate to retract type IVa pili
  16. 1876
    “…Here we consider the possibility that apparent endogenous alpha-synuclein oligomers are in fact conformations of membrane-bound alpha-synuclein and not a bona fide stable soluble species. This perspective posits that the formation of any alpha-synuclein oligomers within the cell is likely toxic and interconversion between monomer and oligomer is tightly controlled. …”
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    Endogenous alpha-synuclein monomers, oligomers and resulting pathology: let’s talk about the lipids in the room
  17. 1877
    “…CONCLUSIONS: Nck adaptors in interaction with Dok1 induce podosome biogenesis and ECM degradation facilitating cancer cell invasion, and therefore a bona fide target of cancer therapy.…”
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    Nck adapter proteins promote podosome biogenesis facilitating extracellular matrix degradation and cancer invasion
  18. 1878
    “…While plant sRNAs showed broad size distribution, viral sRNAs were predominantly 21 and 22 nucleotides long with 5′-terminal uridine or adenine, and were derived from both genomic strands. These bona fide siRNAs are presumably processed from double-stranded RNA precursors by Dicer-like (DCL) 4 and DCL2, respectively, and associated with Argonaute 1 and 2 proteins. …”
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    Plant virome reconstruction and antiviral RNAi characterization by deep sequencing of small RNAs from dried leaves
  19. 1879
    “…CONCLUSIONS: Neutrophils are a bona fide source of circulating nucleosomes in an obesogenic environment and in overweight/obese patients. …”
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    Obesity-induced nucleosome release predicts poor cardio-metabolic health
  20. 1880
    “…Single-cell transcriptome and functional analyses illustrated the cellular trajectory of T lineage induction from PSCs, unveiling the T-lineage specification determined at as early as hemogenic endothelial cell stage and identifying the bona fide pre-thymic progenitors. The induced T cells distributed normally in central and peripheral lymphoid organs and exhibited abundant TCRαβ repertoire. …”
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    Guiding T lymphopoiesis from pluripotent stem cells by defined transcription factors
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