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  1. 1921
    “…To test this, we used vesicular stomatitis virus pseudoviral particles presenting SARS-CoV-2 spike protein on their surface (pp-VSV-SARS-CoV-2 spike), a bona fide system for mimicking SARS-CoV-2 entry into cells. …”
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    Inhibition of acid sphingomyelinase by ambroxol prevents SARS-CoV-2 entry into epithelial cells
  2. 1922
    “…In the present study, we identified OTU domain-containing 7B (OTUD7B), a deubiquitylase belonging to A20 subgroup of ovarian tumor protein superfamily, as a bona fide deubiquitylase of ERα in breast cancer. OTUD7B expression was found to be positively correlated with ERα in breast cancer and associated with poor prognosis. …”
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    OTUD7B stabilizes estrogen receptor α and promotes breast cancer cell proliferation
  3. 1923
    “…Our work underlines the value of bona fide transport experiments to reveal mechanistic features of Na(+)-aspartate symport that cannot be observed in detergent solution. …”
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    Kinetic mechanism of Na(+)-coupled aspartate transport catalyzed by Glt(Tk)
  4. 1924
    “…Using several approaches, we identified ICP4 as a bona fide target gene of Fos that regulated Fos and has Fos response elements within its promoter. …”
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    Fos Facilitates Gallid Alpha-Herpesvirus 1 Infection by Transcriptional Control of Host Metabolic Genes and Viral Immediate Early Gene
  5. 1925
    “…This study demonstrates the successful application of a bona fide small-molecule amyloid inhibitor as a potent anticancer agent.…”
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    Protein mimetic amyloid inhibitor potently abrogates cancer-associated mutant p53 aggregation and restores tumor suppressor function
  6. 1926
    “…Our study documents the existence of endometrial lesions that are histologically indistinct but are bona fide endometrial cancer precursors. © 2021 The Authors. …”
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    Serial genomic analysis of endometrium supports the existence of histologically indistinct endometrial cancer precursors
  7. 1927
    “…Further coimmunoprecipitation (Co-IP) and immunofluorescence assays confirmed that Sun5 and Nesprin3 were indeed bona fide interaction partners that formed the linker of the nucleoskeleton and cytoskeleton (LINC) complex participating in the connection of the head and tail of spermatozoa. …”
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    SUN5 Interacting With Nesprin3 Plays an Essential Role in Sperm Head-to-Tail Linkage: Research on Sun5 Gene Knockout Mice
  8. 1928
    “…This study validates mKRAS peptides as bona fide epitopes facilitating the development of immune therapies targeting this oncoprotein.…”
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    Biochemical and functional characterization of mutant KRAS epitopes validates this oncoprotein for immunological targeting
  9. 1929
    “…Our approach is an efficient way to obtain enriched bona fide vmDA precursors, which could open a new avenue for effective PD treatment.…”
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    Trophoblast glycoprotein is a marker for efficient sorting of ventral mesencephalic dopaminergic precursors derived from human pluripotent stem cells
  10. 1930
    “…Speckle‐type POZ protein (SPOP) and OTU domain‐containing protein 7A (OTUD7A) are identified as the bona fide E3 ligase and deubiquitinase, respectively, that control EWS–FLI1 protein turnover in Ewing sarcoma. …”
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    SPOP and OTUD7A Control EWS–FLI1 Protein Stability to Govern Ewing Sarcoma Growth
  11. 1931
    “…Here, we have investigated the role of Ly6G, a homolog of the human CD177 protein, which has been shown to interact with cell adhesion molecules, and serves as a bona fide marker for neutrophils in mice. We show that Ly6G deficiency decreases the initial infection rate of neutrophils recruited to the site of infection. …”
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    Ly6G deficiency alters the dynamics of neutrophil recruitment and pathogen capture during Leishmania major skin infection
  12. 1932
    “…For this reason, Ftt was developed into a bona fide biological weapon by the USA, by the former USSR, and their respective allies during the previous century. …”
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    Modern Development and Production of a New Live Attenuated Bacterial Vaccine, SCHU S4 ΔclpB, to Prevent Tularemia
  13. 1933
    por Zaman, Aubhishek, Bivona, Trever G
    Publicado 2021
    “…AXL, a receptor tyrosine kinase with bona fide oncogenic capacity, has been associated with the emergence of resistance in an array of cancers with varying pathophysiology and cellular origins, including in non-small-cell lung cancers (NSCLCs). …”
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    Targeting AXL in NSCLC
  14. 1934
    “…In summary, here we report pathogenic global mis-splicing in Huntington’s disease striatum captured by our new intersect-RNA-seq approach that can be readily applied to other neurodegenerative diseases for which bona fide animal models are available.…”
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    Huntington’s disease-specific mis-splicing unveils key effector genes and altered splicing factors
  15. 1935
    “…Expansion microscopy revealed morphologic characteristics of bona fide synaptic boutons of the en passant and terminal type. …”
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    GABAergic Inhibition of Presynaptic Ca(2+) Transients in Respiratory PreBötzinger Neurons in Organotypic Slice Cultures
  16. 1936
    “…We confirm that these cells are bona fide microglia by molecular, morphological and ultrastructural approaches. …”
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    Capillary-associated microglia regulate vascular structure and function through PANX1-P2RY12 coupling in mice
  17. 1937
    “…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has killed more than 4 million humans globally, but there is no bona fide Food and Drug Administration–approved drug-like molecule to impede the COVID-19 pandemic. …”
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    DNA-encoded chemistry technology yields expedient access to SARS-CoV-2 M(pro) inhibitors
  18. 1938
    “…The database is stored in three different formats, following the BIDS common specification: (1) DICOM (data not processed), (2) NIFTI (multimodal images coregistered to PET subject space), (3) NIFTI normalized (images normalized to MNI space). Bona fide researchers can request access to the database via a short form. …”
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    CERMEP-IDB-MRXFDG: a database of 37 normal adult human brain [(18)F]FDG PET, T1 and FLAIR MRI, and CT images available for research
  19. 1939
    “…It is therefore urgent to establish accurate strategies combining bioimaging with high-content image analysis for a bona fide classification. In this study we developed a supervised machine learning method for interphase cell cycle staging of individual adherent cells using in situ fluorescence images of nuclei stained with DAPI. …”
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    A machine learning approach for single cell interphase cell cycle staging
  20. 1940
    por Mellett, Leah, Khader, Shabaana A.
    Publicado 2022
    “…However, it has yet to be determined if S100A8/A9 is a bona-fide biomarker for COVID-19. S100A8/A9 is widely implicated in a variety of inflammatory conditions, such as cystic fibrosis (CF) and chronic obstructive pulmonary disorder (COPD), as well as pulmonary infectious diseases, including tuberculosis and influenza. …”
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    S100A8/A9 in COVID-19 pathogenesis: Impact on clinical outcomes
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