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Mostrando 421 - 440 Resultados de 5,131 Para Buscar '"Finns"', tiempo de consulta: 0.36s Limitar resultados
  1. 421
    “…MR estimates of hypertension from FinnGen and UK Biobank were meta-analyzed using the fixed-effect model given no heterogeneity. …”
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    Causal Effect of Relative Carbohydrate Intake on Hypertension through Psychological Well-Being and Adiposity: A Mendelian Randomization Study
  2. 422
    “…The rule showed good calibration and discrimination in EDC, FinnDiane and CACTI (c-statistic 0.71, 0.79 and 0.79, respectively). …”
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    Progression to microalbuminuria in type 1 diabetes: development and validation of a prediction rule
  3. 423
    “…Summary‐level data for epilepsy were obtained from the FinnGen consortium (4,588 cases and 144 780 noncases). …”
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    Modifiable risk factors for epilepsy: A two‐sample Mendelian randomization study
  4. 424
    “…Integrating transcriptomics and metabolomics individually with FinnGen GWAS results identified 1,597 genes for 790 disease traits. …”
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    Integrating transcriptomics, metabolomics, and GWAS helps reveal molecular mechanisms for metabolite levels and disease risk
  5. 425
    “…METHODS: We considered 859 individuals recruited from the Scottish Diabetes Research Network Type 1 Bioresource (SDRNT1BIO) and 315 individuals from the Finnish Diabetic Nephropathy (FinnDiane) study. All had an entry eGFR between 30 and 75 ml min(−1)[1.73 m](−2), with those from FinnDiane being oversampled for albuminuria. …”
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    Biomarker panels associated with progression of renal disease in type 1 diabetes
  6. 426
    “…Summary-level data on type 2 diabetes are obtained from the DIAGRAM (DIAbetes Genetics Replication And Meta-analysis consortium) consortium (74,124 cases) and FinnGen study (33,043 cases). Data on 10 diabetic complications are obtained from FinnGen and corresponding studies. …”
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    Plasma proteins and onset of type 2 diabetes and diabetic complications: Proteome-wide Mendelian randomization and colocalization analyses
  7. 427
    “…This article proposes methodology for evaluating the accuracy of the pore pressure generation model devised by Byrne, as implemented in a commercial software program using a Mohr-Coulomb-type failure criterion and a Finn constitutive model. The different empirical formulas of liquefaction developed by Seed and Idriss are reviewed, as well as various constitutive models specified in the literature, emphasizing the selection of the Finn model for the liquefaction study. …”
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    Adjustment of a numerical model for pore pressure generation during an earthquake
  8. 428
    “…A suggestive association was observed for genetically predicted higher plasma caffeine levels and lower risk of Parkinson’s disease in the FinnGen consortium. but not in the International Parkinson’s Disease Genomics consortium; no overall association was found (odds ratio 0.92; 95% confidence interval 0.77, 1.10; p = 0.347). …”
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    Plasma Caffeine Levels and Risk of Alzheimer’s Disease and Parkinson’s Disease: Mendelian Randomization Study
  9. 429
    “…This has drawn attention and criticism by dr. S. Finn. We discuss here why we do not agree with his arguments and conclusions, taking the opportunity to make some further considerations on our data.…”
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    On the coincidence excess observed by the Explorer and Nautilus gravitational wave detectors in the year 2001
  10. 430
    por Finnes, Heidi D.
    Publicado 2021
    “…During JADPRO Live Virtual 2020, Heidi D. Finnes, PharmD, BCOP, FHOPA, discussed the pharmacology and indications of medications approved from late 2019 to late 2020 for the management of patients with hematologic malignancies, reviewed pivotal clinical trial data, and covered the adverse events of these hematologic medications.…”
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    2019–2020 Drug Updates in Hematologic Malignancies
  11. 431
    “…The average level of linkage disequilibrium ranged from 0.156 (for Primera) to 0.231 (for Finn). The lowest consistency of gametic phase was estimated between NWS and Finn (0.397), and between NWS and Texel (0.443), respectively. …”
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    Genetic Connectedness Between Norwegian White Sheep and New Zealand Composite Sheep Populations With Similar Development History
  12. 432
    “…Summary level data for outcomes from the FinnGen consortium and UK Biobank were utilized in the discovery and replication stage. …”
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    Causal effects of modifiable risk factors on kidney stones: a bidirectional mendelian randomization study
  13. 433
    “…Furthermore, we demonstrate an association of IRS4 gene locus to a general thyroid disease risk in the FinnGen database. Our findings confirm the role of IRS4 in isolated central hypothyroidism.…”
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    Screening for Mutations in Isolated Central Hypothyroidism Reveals a Novel Mutation in Insulin Receptor Substrate 4
  14. 434
    “…Here we use data from two independent population-based Finnish cohorts (4632 adults aged 25–74 years from the DILGOM study and 1231 twin individuals aged 21–26 years from the FinnTwin12 study) to investigate whether two appetitive traits mediate the associations between known obesity-related genetic variants and adiposity. …”
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    Appetitive traits as behavioural pathways in genetic susceptibility to obesity: a population-based cross-sectional study
  15. 435
    “…Using the Finnish nationwide drug purchase registry with follow-up since 1995, we performed genome-wide association analyses of longitudinal patterns of medication use in hyperlipidemia, hypertension and type 2 diabetes in up to 193,933 individuals (55% women) in the FinnGen study. In meta-analyses of up to 567,671 individuals combining FinnGen with the Estonian Biobank and the UK Biobank, we discovered 333 independent loci (P < 5 × 10(–9)) associated with medication use. …”
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    Genetic predictors of lifelong medication-use patterns in cardiometabolic diseases
  16. 436
    “…METHODS: Our study included two cohorts of longitudinally followed twins: FinnTwin12 (N=651) and the Netherlands Twin Register (NTR) (N=665). …”
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    Longitudinal multi-omics study reveals common etiology underlying association between plasma proteome and BMI trajectories in adolescent and young adult twins
  17. 437
    “…RESULTS: After bidirectional causality by two-sample MR, we verified that genetic predisposition to KSD could increase the risk of coronary atherosclerosis (OR: 4.45×1037; SE=±7.80×10(14), P for MR-Egger =0.024) and cardiomyopathy (OR: 5.35×10(13); SE=±7.18×10(6), P for IVW=0.045 for finn-a-I9_CARDMYO, and OR: 3.60×10(25); SE=±3.26×10(12), P for IVW=0.041 for finn-a-I9_CARDMYOOTH) when we used ukb-b-13537 as exposure group. …”
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    Kidney stone disease and cardiovascular events: a study on bidirectional causality based on mendelian randomization
  18. 438
    “…Summary statistics for digestive system cancers were obtained from the UK Biobank and FinnGen studies. Two-sample MR analyses were performed in each of the two outcome databases, followed by a meta-analysis. …”
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    Investigating Causal Associations of Diet-Derived Circulating Antioxidants with the Risk of Digestive System Cancers: A Mendelian Randomization Study
  19. 439
    “…Summary-level genome-wide association studies (GWAS) datasets for GORD were retrieved from the Neale Lab (GORD(Neale), Ncases = 29975, Ncontrols = 390556) and FinnGen (GORD(Finn), Ncases = 13141, Ncontrols = 89695). …”
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    Genetic estimation of correlations and causalities between multifaceted modifiable factors and gastro-oesophageal reflux disease
  20. 440
    “…Two independent cohorts of European ancestry with endometriosis GWAS summary statistics were used: UK Biobank (4354 cases and 217,500 controls) and FinnGen (8288 cases and 68,969 controls). We conducted MR analyses separately in the UK Biobank and FinnGen, followed by a meta-analysis. …”
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    The effects of coagulation factors on the risk of endometriosis: a Mendelian randomization study
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