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441por Zhao, Cong, Feng, Jun-long, Deng, Sheng, Wang, Xiang-peng, Fu, Yu-jie, Wang, Bin, Li, Hai-song, Meng, Fan-chao, Wang, Ji-sheng, Wang, Xian“…Genetically predicted hypertension is also associated with ED (For the FinnGen, OR = 1.106; 95% CI: 1.027–1.191; P = 0.008. …”
Publicado 2023
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442por Ripatti, Pietari, Rämö, Joel T., Mars, Nina J., Fu, Yu, Lin, Jake, Söderlund, Sanni, Benner, Christian, Surakka, Ida, Kiiskinen, Tuomo, Havulinna, Aki S., Palta, Priit, Freimer, Nelson B., Widén, Elisabeth, Salomaa, Veikko, Tukiainen, Taru, Pirinen, Matti, Palotie, Aarno, Taskinen, Marja-Riitta, Ripatti, Samuli“…We evaluated the impact of polygenic hypercholesterolemia and hypertriglyceridemia to lipid levels in 27 039 individuals from the National FINRISK Study (FINRISK) cohort and to CAD risk in 135 638 individuals (13 753 CAD cases) from the FinnGen project (FinnGen). RESULTS: In FINRISK, median LDL-C was 3.39 (95% CI, 3.38–3.40) mmol/L, and it ranged from 2.87 (95% CI, 2.82–2.94) to 3.78 (95% CI, 3.71–3.83) mmol/L between the lowest and highest 5% of the LDL-C PRS distribution. …”
Publicado 2020
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443por Jones, Samuel E., Maisha, Fahrisa I., Strausz, Satu J., Cade, Brian E., Tervi, Anniina M., Helaakoski, Viola, Broberg, Martin E., Lammi, Vilma, Lane, Jacqueline M., Redline, Susan, Saxena, Richa, Ollila, Hanna M.“…FINDINGS: Utilizing 23 years of registry data and follow-up, we saw that insomnia diagnosis associated with increased risk for infections in FinnGen and in UK Biobank (FinnGen influenza HR = 5.32 [4.09, 6.92], P = 1.02×10(−35), UK Biobank influenza HR = 1.54 [1.37, 1.73], P = 2.49×10(−13)). …”
Publicado 2022
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444“…Summary-level data for outcomes were obtained from the corresponding GWAS and the FinnGen consortium. The random-effects inverse variance weighted (IVW) method was used as the main MR analysis, supplemented by replication analyses using data from the FinnGen. …”
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445por Wu, Hao, Liu, Peng, Gong, Siming, Liu, Xiaoming, Hill, Michael A., Liu, Zhenguo, Xu, Meihua, Xu, Canxia“…GWAS data for estimated glomerular filtration rate from serum creatinine (eGFRcrea), urine albumin–creatinine ratio (uACR), and CKD were obtained from the CKDGen Consortium, and GWAS data for urolithiasis were obtained from the FinnGen consortium. The summary-level GWAS data for IgA nephropathy were obtained from the meta-analysis of UK-biobank, FinnGen, and Biobank Japan. …”
Publicado 2023
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446“…The summary analysis for MS from two separate databases [International Multiple Sclerosis Genetics Consortium (IMSGC), FinnGen] and the summary analysis for breast cancer from Breast Cancer Association Consortium. …”
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447por Williams, Winfred W., Salem, Rany M., McKnight, Amy Jayne, Sandholm, Niina, Forsblom, Carol, Taylor, Andrew, Guiducci, Candace, McAteer, Jarred B., McKay, Gareth J., Isakova, Tamara, Brennan, Eoin P., Sadlier, Denise M., Palmer, Cameron, Söderlund, Jenny, Fagerholm, Emma, Harjutsalo, Valma, Lithovius, Raija, Gordin, Daniel, Hietala, Kustaa, Kytö, Janne, Parkkonen, Maija, Rosengård-Bärlund, Milla, Thorn, Lena, Syreeni, Anna, Tolonen, Nina, Saraheimo, Markku, Wadén, Johan, Pitkäniemi, Janne, Sarti, Cinzia, Tuomilehto, Jaakko, Tryggvason, Karl, Österholm, Anne-May, He, Bing, Bain, Steve, Martin, Finian, Godson, Catherine, Hirschhorn, Joel N., Maxwell, Alexander P., Groop, Per-Henrik, Florez, Jose C.“…-R.O.I.) collection and the Finnish Diabetic Nephropathy Study (FinnDiane), combined with reanalyzed data from the Genetics of Kidneys in Diabetes U.S. …”
Publicado 2012
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448por Wang, Yong-Bo, Yan, Si-Yu, Li, Xu-Hui, Huang, Qiao, Luo, Li-Sha, Wang, Yun-Yun, Huang, Jiao, Jin, Ying-Hui, Zeng, Xian-Tao“…The summary statistics for the associations of exposure-related SNPs with type 2 diabetes were drawn from the GWAS in the Diabetes Genetics Replication and Meta-analysis (DIAGRAM) consortium and the FinnGen consortium R5 release, respectively. For the reversed causal inference, 132 and 49 SNPs associated with type 2 diabetes from the DIAGRAM consortium and the FinnGen consortium R5 release were included, and the summary-level statistics were obtained from the Gene-Lifestyle Interactions in Dental Endpoints consortium. …”
Publicado 2022
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449por O′Mara, Frank, Richards, Karl G, Shalloo, Laurence, Donnellan, Trevor, Finn, John A, Lanigan, GaryEnlace del recurso
Publicado 2021
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450“…In the previous determination [Finn & Musti (1950 ▶). J. Soc. Chem. Ind. (London), 69, S849] of the title compound, C(13)H(12)O(2), the three-dimensional coordinates and displacement parameters were not reported. …”
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451por Merabishvili, Maia, Vervaet, Chris, Pirnay, Jean-Paul, De Vos, Daniel, Verbeken, Gilbert, Mast, Jan, Chanishvili, Nino, Vaneechoutte, Mario“…Staphylococcus aureus phage ISP was lyophilized, using an Amsco-Finn Aqua GT4 freeze dryer, in the presence of six different stabilizers at different concentrations. …”
Publicado 2013
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453por Zhang, Han, Yuan, Shuai, Li, Yong, Li, Doudou, Yu, Zengli, Hu, Lidan, Li, Xue, Wang, Yuming, Larsson, Susanna C.“…Summary-level data for CKD were derived from CKDGen consortium (64,164 cases and 625,219 controls) and FinnGen consortium (3,902 cases and 212,841 controls). …”
Publicado 2023
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454por He, Qiang, Wang, Wenjing, Xiong, Yang, Tao, Chuanyuan, Ma, Lu, Ma, Junpeng, You, Chao“…Genus.Coprococcus3 and genus.Anaerotruncus were validated in FinnGen datasets. Nine, twelve, and seven bacterial entities were identified for migraine, MA, and MO, respectively. …”
Publicado 2023
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455“…Sensitive tests were conducted using robust MR methods. Results from FinnGen and UKB were combined using the fixed model. …”
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456“…Datasets pertaining to the 33 types of cancer investigated in this study were acquired from the FinnGen genome-wide association study. RESULTS: The selected instrumental variable lowered fibrinogen levels, confirming its ability to mimic IL-6R blockade. …”
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457por Yuan, Shuai, Carter, Paul, Vithayathil, Mathew, Kar, Siddhartha, Mason, Amy M., Burgess, Stephen, Larsson, Susanna C.“…Results for colorectal cancer were consistent in FinnGen and the combined OR(SD) was 1.16 (95% CI 1.08, 1.25, p < 0.001). …”
Publicado 2021
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458“…We used endpoints for pain in the FinnGen Release 5 (R5) (N = 218,379), and a non-overlapping sample for insomnia (UK Biobank (UKBB) and 23andMe, N = 1,331,010 or UKBB alone N = 453,379). …”
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459por Faulstich, Sam D., Schissler, A. Grant, Strickland, Matthew J., Holmes, Heather A.“…Results indicate that FINN and GFED likely underestimate emissions, while the MFLEI products likely overestimate emissions. …”
Publicado 2022
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460“…Consistent results were obtained in the FinnGen consortium (OR = 0.890, 95% CI, 0.467–1.697). …”
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