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481por Finn, J Paul, Moriarty, John, Plotnik, Adam, Yoshida, Takegawa, Shemin, Richard J, Aksoy, Olcay, Suh, William MEnlace del recurso
Publicado 2016
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482por Gunn, Lynda, Finn, Sarah, Hurley, Daniel, Bai, Li, Wall, Ellen, Iversen, Carol, Threlfall, John E., Fanning, SéamusEnlace del recurso
Publicado 2017
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483por Miyashita, Tadayoshi, Koizumi, Ryosuke, Sagane, Yoshimasa, Minami, Kazuhiro, Ito, Minoru, Watanabe, Toshihiro, Niwa, Koichi“…The test was carried out by performing a standard patch test using a Finn Chamber on Scanpor tape. The oils were applied to the participant's back using the tape and left in place for 24 h. …”
Publicado 2017
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489por Jones, Samuel E., Maisha, Fahrisa I., Strausz, Satu J., Lammi, Vilma, Cade, Brian E., Tervi, Anniina, Helaakoski, Viola, Broberg, Martin E., Lane, Jacqueline M., Redline, Susan, Saxena, Richa, Ollila, Hanna M.“…FINDINGS: Utilizing 23 years of registry data and follow-up, we discovered that insomnia diagnosis associated with increased risk for infections (FinnGen influenza Cox’s proportional hazard (CPH) HR = 4.34 [3.90, 4.83], P = 4.16 × 10(−159), UK Biobank influenza CPH HR = 1.54 [1.37, 1.73], P = 2.49 × 10(−13)). …”
Publicado 2023
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490por Wang, Jiachen, Yang, Mingyi, Xu, Ke, Wan, Xianjie, Xie, Jiale, Yu, Hui, Fang, Jiaxin, Wang, Zehua, Xu, Peng“…Constipation, as an outcome variable, was obtained from the FinnGen project containing 26,919 cases and 282,235 controls and another UK Biobank dataset containing 3,328 cases and 459,682 controls. …”
Publicado 2023
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491“…GWAS datasets of AD and AD onset age were obtained from the FinnGen bank. A bidirectional two-sample analysis was performed to explore the causality between dental caries and AD. …”
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492por Vuoksimaa, Eero, Saari, Toni T., Aaltonen, Aino, Aaltonen, Sari, Herukka, Sanna-Kaisa, Iso-Markku, Paula, Kokkola, Tarja, Kyttälä, Aija, Kärkkäinen, Sari, Liedes, Hilkka, Ollikainen, Miina, Palviainen, Teemu, Ruotsalainen, Ilona, Toivola, Auli, Urjansson, Mia, Vasankari, Tommi, Vähä-Ypyä, Henri, Forsberg, Markus M., Hiltunen, Mikko, Jalanko, Anu, Kälviäinen, Reetta, Kuopio, Teijo, Lähteenmäki, Jaakko, Nyberg, Pia, Männikkö, Minna, Serpi, Raisa, Siltanen, Sanna, Palotie, Aarno, Kaprio, Jaakko, Runz, Heiko, Julkunen, Valtteri“…ETHICS AND DISSEMINATION: This recall study consists of FTC/THL/FinnGen participants whose data were acquired in accordance with the Finnish Biobank Act. …”
Publicado 2023
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493“…METHODS: 20 independent single nucleotide polymorphisms (SNPs) associated with diabetic retinopathy were selected from the FinnGen consortium. Summary-level data for diabetic nephropathy were obtained from the publicly available genome-wide association studies (GWAS) database, FinnGen and CKDGen consortium. …”
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494“…The EC Association Consortium (ECAC) performed a genome-wide association study (GWAS) analysis of 12,906 cases and 108,979 controls. FinnGen Consortium performed a GWAS analysis of 1,967 EC cases and 167,189 controls. …”
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495por Larsson, Susanna C., Höijer, Jonas, Sun, Jing, Li, Xue, Burgess, Stephen, Michaëlsson, Karl“…The association between ghrelin and gastrointestinal cancer was examined through a two-sample MR analysis using the identified genetic variants as instruments and GWAS data from the UK Biobank, FinnGen, and a colorectal cancer consortium. RESULTS: GWAS found associations between multiple genetic variants within ±200 kb of the GHRL gene and plasma ghrelin. …”
Publicado 2023
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496por Wadén, Johan, Forsblom, Carol, Thorn, Lena M., Gordin, Daniel, Saraheimo, Markku, Groop, Per-Henrik“…Therefore, we investigated the longitudinal associations between A1C variability and diabetes complications in patients with type 1 diabetes in the observational Finnish Diabetic Nephropathy (FinnDiane) Study. RESEARCH DESIGN AND METHODS: A total of 2,107 patients in the FinnDiane Study had complete data on renal status and serial measurements of A1C from baseline to follow-up (median 5.7 years), and 1,845 patients had similar data on cardiovascular disease (CVD) events. …”
Publicado 2009
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497por Krolewski, Andrzej S., Warram, James H., Forsblom, Carol, Smiles, Adam M., Thorn, Lena, Skupien, Jan, Harjutsalo, Valma, Stanton, Robert, Eckfeldt, John H., Inker, Lesley A., Groop, Per-Henrik“…RESULTS: Although CKD staging by eGFRcyst was concordant with that by eGFRcreat for 62% of Joslin patients and 73% of FinnDiane patients, those given a higher stage by eGFRcyst than eGFRcreat had a significantly higher risk of ESRD than those with concordant staging in all three cohorts (hazard ratio 2.3 [95% CI 1.8–3.1]). …”
Publicado 2012
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498por Skupien, Jan, Smiles, Adam M., Valo, Erkka, Ahluwalia, Tarunveer S., Gyorgy, Beata, Sandholm, Niina, Croall, Stephanie, Lajer, Maria, McDonnell, Kevin, Forsblom, Carol, Harjutsalo, Valma, Marre, Michel, Galecki, Andrzej T., Tregouet, David-Alexandre, Wu, Chun Yi, Mychaleckyj, Josyf C., Nickerson, Helen, Pragnell, Marlon, Rich, Stephen S., Pezzolesi, Marcus G., Hadjadj, Samy, Rossing, Peter, Groop, Per-Henrik, Krolewski, Andrzej S.“…In adjusted analysis, ESRD risk was highest in Joslin versus reference FinnDiane (hazard ratio [HR] 1.44, P = 0.003) and lowest in Steno (HR 0.54, P < 0.001). …”
Publicado 2019
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499por Larsson, Susanna C., Mason, Amy M., Kar, Siddhartha, Vithayathil, Mathew, Carter, Paul, Baron, John A., Michaëlsson, Karl, Burgess, Stephen“…METHODS: We obtained genetic association estimates for cancer from the UK Biobank (n = 367,643 women and men), FinnGen consortium (n = 135,638 women and men), Breast Cancer Association Consortium (n = 228,951 women), and Prostate Cancer Association Group to Investigate Cancer Associated Alterations in the Genome consortium (n = 140,254 men). …”
Publicado 2020
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500por Titova, Olga E., Michaëlsson, Karl, Vithayathil, Mathew, Mason, Amy M., Kar, Siddhartha, Burgess, Stephen, Larsson, Susanna C.“…However, none of these associations passed the multiple comparison threshold and two‐sample MR analysis using FinnGen data did not confirm these findings. In conclusion, this MR study does not provide strong evidence to support causal associations of sleep duration with risk of overall and site‐specific cancers. …”
Publicado 2020
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