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  1. 781
    “…The association of these instrumental variables with urolithiasis was studied in a cohort from FinnGen Consortium. RESULTS: Among the 15 studied food intake exposures, tea intake (odds ratio [OR] = 0.433, 95% confidence interval [CI] = 0.281–0.667, p value = 1.470 × 10(–4)) and fresh fruit intake (OR = 0.358, 95% CI = 0.185–0.694, p value = 0.002) were found to significantly reduce the risk of the calculus of kidney and ureter. …”
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    Mendelian randomization analysis reveals fresh fruit intake as a protective factor for urolithiasis
  2. 782
    “…We duplicated the MR analyses using datasets from AF HRC studies and the FinnGen Consortium, and then conducted a meta-analysis which combined the main results. …”
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    Protective effect of uridine on atrial fibrillation: a Mendelian randomisation study
  3. 783
    “…METHODS: A Mendelian randomization (MR) study was conducted to quantify the impact of 191 gut microbiome taxa's instrumental variables from the MibioGen Genome-wide association study (GWAS) on scoliosis risk using data from the FinnGen GWAS (1168 cases and 16,4682 controls). Inverse variance weighted (IVW) was the main method, and MR results were verified by sensitive analysis. …”
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    Causal effects of gut microbiota on scoliosis: A bidirectional two-sample mendelian randomization study
  4. 784
    “…To explore the intricate relationship between GM and Ps as well as PsA, we harnessed the comprehensive resources of the FinnGen database, encompassing a vast cohort of individuals, including 4510 Ps cases and 212 242 controls and 1637 PsA cases and 212 242 controls. …”
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    Investigating the gut microbiota's influence on psoriasis and psoriatic arthritis risk: a Mendelian randomization analysis
  5. 785
    “…METHODS: A gut microbiome genome-wide association study conducted by the MiBioGen consortium was used as exposure data, and summary statistics of endometriosis were obtained from the FinnGen consortium R8 release data. Inverse variance weighted, MR-Egger, weighted median, weighted model, and simple model analyses were applied to examine the causal relationship, and sensitivity analyses were conducted to validate the robustness of the results. …”
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    Causal effects of gut microbiome on endometriosis: a two-sample mendelian randomization study
  6. 786
    “…We investigated the association between diet and serum LPS activity in 668 individuals with type 1 diabetes in the FinnDiane Study. Serum LPS activity was determined using the Limulus Amoebocyte Lysate assay. …”
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    Dietary patterns reflecting healthy food choices are associated with lower serum LPS activity
  7. 787
    “…In contrast, in our modified protocol (MP) 25 mg Aldara and vaseline are applied simultaneously in separate Finn chambers over the dorsal skin of mice. In both the OP and MP groups, histology showed unequivocal hallmarks of psoriasiform dermatitis. …”
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    Methodological refinement of Aldara-induced psoriasiform dermatitis model in mice
  8. 788
    “…METHODS: Participants were 130 women from the FinnBrain Birth Cohort study. Alexithymia was measured with the Toronto Alexithymia Scale (TAS-20). …”
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    Alexithymic Traits and Hair Cortisol Concentrations in Pregnant Women
  9. 789
    “…We investigated three Finnish cohorts separately and in a meta-analysis (n = 7178), namely population-based FINRISK97, FinnTwin16 consisting of young adult twins, and Parogene, a random cohort of cardiac patients. …”
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    Endotoxemia is associated with an adverse metabolic profile
  10. 790
    “…This signal was independently replicated in the FinnGen cohort, which contains 1028 cases and 196,986 controls (combined p = 2.2 × 10(−20)), firmly associating this variant as an IPF risk allele. …”
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    Identification of a missense variant in SPDL1 associated with idiopathic pulmonary fibrosis
  11. 791
    “…Data used for our analyses include the FinnGen study (N = 309,154) and the UK Biobank project (N = 343,672). …”
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    Integration of questionnaire-based risk factors improves polygenic risk scores for human coronary heart disease and type 2 diabetes
  12. 792
    “…Here we combined whole-exome sequencing in 392,814 UK Biobank participants with imputed genotypes from 260,405 FinnGen participants (653,219 total individuals) to conduct association meta-analyses for 744 disease endpoints across the protein-coding allelic frequency spectrum, bridging the gap between common and rare variant studies. …”
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    Genetic associations of protein-coding variants in human disease
  13. 793
    “…The data of the GWAS outcomes were obtained from United Kingdom Biobank, FinnGen Biobank and the datasets of corresponding consortia. …”
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    The Association Between Vitamin C and Cancer: A Two-Sample Mendelian Randomization Study
  14. 794
    “…In a large Finnish biobank study FinnGen, we identified an association between an inframe insertion rs534125149 in MFGE8 (encoding lactadherin) and protection against coronary atherosclerosis. …”
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    Inframe insertion and splice site variants in MFGE8 associate with protection against coronary atherosclerosis
  15. 795
    por Wu, E., Ni, Jun-Tao, Xie, Tian, Tao, Lin
    Publicado 2022
    “…Summary data of CRC was from the FinnGen consortium. Based on the results of MR using inverse-variance weighted method, we found that genetically determined major depressive disorder (odds ratio = 1.06, 95% confidence interval = 0.77–1.45) or major depression (odds ratio = 0.77, 95% confidence interval = 0.57–1.04) did not causally increase CRC risk. …”
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    Noncausal effects of genetic predicted depression and colorectal cancer risk: A Mendelian randomization study
  16. 796
    “…About half of these IOP genes are also associated with glaucoma phenotypes in UKB and the FinnGen cohort. Six of these genes, i.e. ADRB1, PTPRB, RPL26, RPL10A, EGLN2, and MTOR, are drug targets that are either established for clinical treatment or in clinical trials. …”
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    Whole-exome sequencing study identifies rare variants and genes associated with intraocular pressure and glaucoma
  17. 797
    “…SNPs related to AS were obtained from the FinnGen consortium (2252 cases and 227,338 controls). …”
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    No Evidence to Support a Causal Relationship between Circulating Adiponectin Levels and Ankylosing Spondylitis: A Bidirectional Two-Sample Mendelian Randomization Study
  18. 798
    “…We analyze genome-wide association to eight upper respiratory diseases (61,195 cases) among 260,405 FinnGen participants, meta-analyzing diseases in four groups based on an underlying genetic correlation structure. …”
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    Inflammatory and infectious upper respiratory diseases associate with 41 genomic loci and type 2 inflammation
  19. 799
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    Characterization of pain-, anxiety-, and cognition-related behaviors in the complete Freund's adjuvant model of chronic inflammatory pain in Wistar–Kyoto rats
  20. 800
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    A hyperspectral plant health monitoring system for space crop production
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