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  1. 1441
    “…Genome-wide significant genetic instruments (p < 5 × 10(–8)) for risk factors were extracted from European-descent genome-wide association studies, whereas aortic aneurysm genetic instruments were selected from the UK Biobank and FinnGen cohort. The inverse-variance weighted MR was used as the main analysis, and MR-Egger (MRE), weighted median MR, MR pleiotropy residual sum and outlier, and Phenoscanner searching were performed as sensitivity analyses. …”
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    Association of cardiovascular risk factors and lifestyle behaviors with aortic aneurysm: A Mendelian randomization study
  2. 1442
    “…The MR analyses were replicated using FinnGen datasets, and the main results were combined in meta−analyses. …”
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    Protective Effects of Circulating TIMP3 on Coronary Artery Disease and Myocardial Infarction: A Mendelian Randomization Study
  3. 1443
    “…The summary statistics of daytime sleepiness were from UK Biobank (n = 452,071) and LBP were provided by the FinnGen Release 6 (210,645 individuals with 16,356 LBP cases and 194,289 controls) or UK Biobank (5,423 cases versus 355,771 controls). …”
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    Association of insomnia and daytime sleepiness with low back pain: A bidirectional mendelian randomization analysis
  4. 1444
    “…Replication analyses were performed using GWAS datasets from FinnGen. RESULTS: In the meta-analysis of inverse-variance weighted estimates from different data sources, genetically determined higher FI conferred an odds ratio (OR) of 1.46 [95% confidence interval (CI): 1.13 to 1.87; P=0.003] for CAD, 1.62 (95% CI: 1.21 to 2.17, P=0.001) for MI, and 1.46 (95% CI: 1.24 to 1.72; P=4.89×10(−6)) for HF. …”
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    Frailty index and risk of cardiovascular diseases: a mendelian randomization study
  5. 1445
    “…METHODS: Summary statistics from genome-wide association studies (GWAS) for VEGF and VTE were obtained from published meta-analysis studies and the FinnGen consortium, respectively. Independent genetic variables significantly associated with exposure were selected as instrumental variables. …”
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    Vascular endothelial growth factor and the risk of venous thromboembolism: a genetic correlation and two-sample Mendelian randomization study
  6. 1446
    “…Genetically predicted H. pylori infection showed no association with NAFLD both in FinnGen GWAS (OR, 1.048; 95% CI, 0.778–1.411; value of p = 0.759) and the GWAS conducted by Anstee (OR, 0.775; 95% CI, 0.475–1.265; value of p = 0.308). …”
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    No evidence for a causal link between Helicobacter pylori infection and nonalcoholic fatty liver disease: A bidirectional Mendelian randomization study
  7. 1447
    “…The associations identified in MR-PheWAS were examined by two-sample MR analysis using data from the FinnGen study (n=260,405) and international consortia. …”
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    Health effects of milk consumption: phenome-wide Mendelian randomization study
  8. 1448
    “…Summary data of diabetic microvascular complications were derived from the FinnGen study (3,283 cases and 181,704 controls for diabetic nephropathy, and 14,584 cases and 176,010 controls for diabetic retinopathy, both were of European ancestry). …”
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    The association of alanine aminotransferase and diabetic microvascular complications: A Mendelian randomization study
  9. 1449
    “…Lastly, we replicated two loci including variants near SOX5 and LOC101928519 associated with suicidal attempts identified in the ISGC and MVP meta-analysis using the independent FinnGen samples. Suicide death and suicidal behavior showed positive genetic correlations with depression, schizophrenia, pain, and suicidal attempt, and negative genetic correlation with educational attainment. …”
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    Genome-wide association study meta-analysis of suicide death and suicidal behavior
  10. 1450
    “…The summary GWAS data for the dose of depression medications were derived from the FinnGen consortium (58,842 cases and 59,827 controls). …”
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    Does Having Rheumatoid Arthritis Increase the Dose of Depression Medications? A Mendelian Randomization Study
  11. 1451
    “…METHODS: Two-sample Mendelian randomization (MR) was performed based on genome-wide association studies (GWAS) summary data from UK Biobank and FinnGen to evaluate the causal effect of meat intake [processed meat, red meat (pork, beef, and lamb), and white meat (poultry)] on DCTs (esophageal, stomach, liver, biliary tract, pancreatic, and colorectal cancers). …”
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    Processed meat, red meat, white meat, and digestive tract cancers: A two-sample Mendelian randomization study
  12. 1452
    “…Our pipeline is demonstrated using two important data sources, initially organized according to different data models: the NHGRI-EBI GWAS Catalog and FinnGen (University of Helsinki). The integration effort finally allows us to use these datasets within multi-sample processing queries that respond to important biological questions. …”
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    Processing genome-wide association studies within a repository of heterogeneous genomic datasets
  13. 1453
    “…Grimnes: None. J. Skov: None. T. Finnes: None. S.F. Valland: None. S.E. Holte: None. …”
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    SAT285 Biomarkers For Cardiovascular Disease And Inflammation Are Altered In Autoimmune Addison's Disease
  14. 1454
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    Rates and Determinants of Uptake and Use of an Internet Physical Activity and Weight Management Program in Office and Manufacturing Work Sites in England: Cohort Study
  15. 1455
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    Toward a Digital Platform for the Self-Management of Noncommunicable Disease: Systematic Review of Platform-Like Interventions
  16. 1456
    “…Also, BMI data were not available for all (63% for FinnGen, 76% for EstBB), and the biobank setting limited the accessibility of PCOS phenotypes and laboratory values. …”
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    Leveraging Northern European population history: novel low-frequency variants for polycystic ovary syndrome
  17. 1457
    por Cowell, Finn
    Publicado 2022
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    100 years of Haldane's rule
  18. 1458
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    In reply: Sex-specific outcomes in COVID-19: missing pieces of the puzzle
  19. 1459
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    Improving the biological interfacing capability of diketopyrrolopyrrole polymers via p-type doping
  20. 1460
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    Preparation and Biological Properties of Oligonucleotide-Functionalized Virus-like Particles
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