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Mostrando 141 - 160 Resultados de 641 Para Buscar '"Flims"', tiempo de consulta: 0.21s Limitar resultados
  1. 141
    “…In Escherichia coli, the chemotaxis response regulator CheY-P binds to FliM, a component of the switch complex at the base of the bacterial flagellar motor, to modulate the direction of motor rotation. …”
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    Robustness in an Ultrasensitive Motor
  2. 142
    “…The classification accuracy for combined FLIM and OCT features was estimated to be 87.4%, which was statistically higher than accuracy based on only FLIM (83.2%) or OCT (81.0%) features. …”
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    Automated analysis of multimodal fluorescence lifetime imaging and optical coherence tomography data for the diagnosis of oral cancer in the hamster cheek pouch model
  3. 143
    “…However, FLIM of NAD(P)H has not been performed in a light-sheet geometry, which is advantageous for rapid imaging of cells within live 3D samples. …”
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    Light-sheet autofluorescence lifetime imaging with a single-photon avalanche diode array
  4. 144
    “…Widefield maFLIM endoscopy thus holds potential for automated in situ detection of oral dysplasia and cancer.…”
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    Machine-Learning Assisted Discrimination of Precancerous and Cancerous from Healthy Oral Tissue Based on Multispectral Autofluorescence Lifetime Imaging Endoscopy
  5. 145
    “…The FLIm device enabled data acquisition at room light and rapid ([Formula: see text]) augmentation of FLIm parameters on the surgical field-of-view. …”
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    First in patient assessment of brain tumor infiltrative margins using simultaneous time-resolved measurements of 5-ALA-induced PpIX fluorescence and tissue autofluorescence
  6. 146
    “…The recent innovations and commercialisation of fast time-domain FLIM systems are likely to popularise FLIM within the biomedical community, to impact biomedical research positively and to foster the adoption of other FLIM techniques as well. …”
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    Fast single-cell biochemistry: theory, open source microscopy and applications
  7. 147
    “…This study evaluates the potential for fluorescence lifetime imaging (FLIm) to enhance intraoperative decisionmaking during robotic-assisted surgery of oropharyngeal cancer. …”
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    Fluorescence lifetime imaging for intraoperative cancer delineation in transoral robotic surgery
  8. 148
    “…The FLIM method combined with unsupervised machine learning (FLIM-ML) had a sensitivity and specificity of 90.9% and 100%, respectively, significantly higher than those of the cytology approach. …”
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    Early Detection of Cervical Cancer by Fluorescence Lifetime Imaging Microscopy Combined with Unsupervised Machine Learning
  9. 149
    “…Here we introduce a new deep learning-based method termed flimGANE (fluorescence lifetime imaging based on Generative Adversarial Network Estimation) that can rapidly generate accurate and high-quality FLIM images even in the photon-starved conditions. …”
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    Generative adversarial network enables rapid and robust fluorescence lifetime image analysis in live cells
  10. 150
    “…This study delineates the correlative imaging of cells with FLIM and electron microscopy (EM). Human fibroblasts were cultivated in a microscopy slide bearing a coordinate system and FLIM measurement was conducted. …”
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    Fluorescence lifetime imaging and electron microscopy: a correlative approach
  11. 151
    “…Using p-TCSPC, 256×256 pixel FLIM maps (300×300 µm(2)) are acquired within 468 ms while 131×131 pixel FLIM maps (75×75 µm(2)) can be acquired every 82 ms in 115 µm depth in the spinal cord of CerTN L15 mice. …”
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    Parallelized TCSPC for Dynamic Intravital Fluorescence Lifetime Imaging: Quantifying Neuronal Dysfunction in Neuroinflammation
  12. 152
    “…The sensitivity, specificity, and positive predictive value for combined FLIm-IVUS (89, 99, 89 %) were better than FLIm (70, 98, 88 %) and IVUS (45, 94, 62 %) alone in distinguishing between pathologies. …”
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    Fluorescence Lifetime Imaging Combined with Conventional Intravascular Ultrasound for Enhanced Assessment of Atherosclerotic Plaques: an Ex Vivo Study in Human Coronary Arteries
  13. 153
    “…Single photon avalanche diode (SPAD) array sensors can increase the imaging speed for fluorescence lifetime imaging microscopy (FLIM) by transitioning from laser scanning to widefield geometries. …”
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    Light sheet autofluorescence lifetime imaging with a single photon avalanche diode array
  14. 154
    “…Fluorescence intensity, lifetime, and anisotropy images of solid phantoms were investigated by FLIM. The exploration of optical properties and molecular imaging combined with DR and FLIM methods is a new approach that has not been established until now. …”
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    Diffusion Reflection and Fluorescence Lifetime Imaging Microscopy Study of Fluorophore-Conjugated Gold Nanoparticles or Nanorods in Solid Phantoms
  15. 155
    “…Spatial and temporal variation of construct ECM component was detected by FLIm. OCT reveals structural defects (voids and cysts). …”
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    Multimodal fluorescence lifetime imaging and optical coherence tomography for longitudinal monitoring of tissue-engineered cartilage maturation in a preclinical implantation model
  16. 156
    “…Recent studies showed that the copy number of FliM in the switch complex and the fraction of FliM that exchanges vary with the direction of flagellar rotation. …”
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    Stoichiometry and Turnover of the Bacterial Flagellar Switch Protein FliN
  17. 157
    “…Because FLIm yielded massive biochemical readouts, the authors incorporated machine learning framework into FLIm, and ultimately, their approach enabled an automated, quantitative imaging of multiple key components relevant for plaque destabilization.…”
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    Comprehensive Assessment of High-Risk Plaques by Dual-Modal Imaging Catheter in Coronary Artery
  18. 158
    “…An alternative method for monitoring the activities of the FRET-based biosensor proteins is fluorescence lifetime imaging microscopy (FLIM). FLIM measurements are made in the time domain, and are not affected by factors that commonly limit intensity measurements. …”
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    Monitoring Biosensor Activity in Living Cells with Fluorescence Lifetime Imaging Microscopy
  19. 159
    por Smolen, Justin A, Wooley, Karen L
    Publicado 2022
    “…This improved accuracy was maintained even when the FLIM images were generated by a U-Net CNN trained on only a few example FLIM images.…”
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    Fluorescence lifetime image microscopy prediction with convolutional neural networks for cell detection and classification in tissues
  20. 160
    “…Tissues were deparaffinized and subjected to MPM-FLIM using an experimental MPM set-up equipped with a time correlated single photon counting module enabling FLIM. …”
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    Report on fluorescence lifetime imaging using multiphoton laser scanning microscopy targeting sentinel lymph node diagnostics
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