Retrospective, real‐life study of venetoclax plus azacitidine or low‐dose cytarabine in French patients with acute myeloid leukemia ineligible for intensive chemotherapy

por Laloi, Louise, Billotey, Natacha Chaumard, Dumas, Pierre‐Yves, Paul, Franciane, Villate, Alban, Simand, Célestine, Fornecker, Luc, Puisset, Florent, Bertoli, Sarah, Simonet, Marion Boissard, Laribi, Kamel, Houyou, Dyhia, Santagostino, Alberto, Michel, Claire, Guepin, Gabrielle Roth, Guerineau, Elodie, Tabrizi, Reza, Hunault, Mathilde, Giltat, Aurélien, Kaphan, Eléonore, Bulabois, Claude, Cartet, Elodie, Rocher, Clément, Lachenal, Florence, Morisset, Stéphane, Récher, Christian, Pigneux, Arnaud, Belhabri, Amine, Michallet, Mauricette, Michallet, Anne‐Sophie
Publicado 2022

Funding evidence‐based conservation

por Parks, Danni, Al‐Fulaij, Nida, Brook, Clare, Butchart, Stuart H. M., Collomb, Jean‐Gaël, Cope, David, Dowell, Simon, Falkingham, Becky, Frick, Winifred F., Gibbs, Douglas, Gray, Emily E., Heard, Nicolas, Leventis, Anastasios (Tasso), Mastro, Kate, Meredith, Helen, Mickleburgh, Simon, Miller, Florence, Muir, Matthew, Nuijten, Rascha J. M., Ockendon, Nancy, Owen, Nisha R., Owens, Jacob R., Rodríguez, Jon Paul, Roy, Sugoto, Tully, Elizabeth, Vié, Jean‐Christophe
Publicado 2022

P315: TP53 ALTERATIONS AND MRD REFINE PROGNOSIS OF ADULT KMT2A-REARRANGED B-ALL

por Kim, Rathana, Bergugnat, Hugo, Pasquier, Florence, Raffoux, Emmanuel, Larcher, Lise, Passet, Marie, Pastoret, Cedric, Nathalie, Grardel, Asnafi, Vahid, Delabesse, Eric, Caye-Eude, Aurélie, Meyer, Claus, Masrschalek, Rolf, Thiebaut-Bertrand, Anne, Balsat, Marie, Escoffre, Martine, Blum, Sabine, Baumann, Michael, Banos, Anne, Straetmans, Nicole, Pilar Gallego Hernanz, Maria, Chalandon, Yves, Graux, Carlos, Leguay, Thibaut, Hunault, Mathilde, Huguet, Françoise, Lhéritier, Véronique, Soulier, Jean, Boissel, Nicolas, Clappier, Emmanuelle
Publicado 2023

CD36 Drives Metastasis and Relapse in Acute Myeloid Leukemia

por Farge, Thomas, Nakhle, Jean, Lagarde, Damien, Cognet, Guillaume, Polley, Nathaniel, Castellano, Rémy, Nicolau, Marie-Laure, Bosc, Claudie, Sabatier, Marie, Sahal, Ambrine, Saland, Estelle, Jeanson, Yannick, Guiraud, Nathan, Boet, Emeline, Bergoglio, Camille, Gotanègre, Mathilde, Mouchel, Pierre-Luc, Stuani, Lucille, Larrue, Clément, Sallese, Marie, De Mas, Véronique, Moro, Cedric, Dray, Cédric, Collette, Yves, Raymond-Letron, Isabelle, Ader, Isabelle, Récher, Christian, Sarry, Jean-Emmanuel, Cabon, Florence, Vergez, François, Carrière, Audrey
Publicado 2023

Structural and mechanistic insights into the inhibition of respiratory syncytial virus polymerase by a non-nucleoside inhibitor

por Yu, Xiaodi, Abeywickrema, Pravien, Bonneux, Brecht, Behera, Ishani, Anson, Brandon, Jacoby, Edgar, Fung, Amy, Adhikary, Suraj, Bhaumik, Anusarka, Carbajo, Rodrigo J., De Bruyn, Suzanne, Miller, Robyn, Patrick, Aaron, Pham, Quyen, Piassek, Madison, Verheyen, Nick, Shareef, Afzaal, Sutto-Ortiz, Priscila, Ysebaert, Nina, Van Vlijmen, Herman, Jonckers, Tim H. M., Herschke, Florence, McLellan, Jason S., Decroly, Etienne, Fearns, Rachel, Grosse, Sandrine, Roymans, Dirk, Sharma, Sujata, Rigaux, Peter, Jin, Zhinan
Publicado 2023

Structure-Based Design of Orally Bioavailable 1H-Pyrrolo[3,2-c]pyridine Inhibitors of Mitotic Kinase Monopolar Spindle 1 (MPS1)

por Naud, Sébastien, Westwood, Isaac M., Faisal, Amir, Sheldrake, Peter, Bavetsias, Vassilios, Atrash, Butrus, Cheung, Kwai-Ming J., Liu, Manjuan, Hayes, Angela, Schmitt, Jessica, Wood, Amy, Choi, Vanessa, Boxall, Kathy, Mak, Grace, Gurden, Mark, Valenti, Melanie, de Haven Brandon, Alexis, Henley, Alan, Baker, Ross, McAndrew, Craig, Matijssen, Berry, Burke, Rosemary, Hoelder, Swen, Eccles, Suzanne A., Raynaud, Florence I., Linardopoulos, Spiros, van Montfort, Rob L. M., Blagg, Julian
Publicado 2013

Multicenter case–control study protocol of pneumonia etiology in children: Global Approach to Biological Research, Infectious diseases and Epidemics in Low-income countries (GABRIE...

por Picot, Valentina Sanchez, Bénet, Thomas, Messaoudi, Melina, Telles, Jean-Noël, Chou, Monidarin, Eap, Tekchheng, Wang, Jianwei, Shen, Kunling, Pape, Jean-William, Rouzier, Vanessa, Awasthi, Shally, Pandey, Nitin, Bavdekar, Ashish, Sanghvi, Sonali, Robinson, Annick, Contamin, Bénédicte, Hoffmann, Jonathan, Sylla, Maryam, Diallo, Souleymane, Nymadawa, Pagbajabyn, Dash-Yandag, Budragchaagiin, Russomando, Graciela, Basualdo, Wilma, Siqueira, Marilda M, Barreto, Patricia, Komurian-Pradel, Florence, Vernet, Guy, Endtz, Hubert, Vanhems, Philippe, Paranhos-Baccalà, Gláucia
Publicado 2014

Comparison of two strategies for initiating renal replacement therapy in the intensive care unit: study protocol for a randomized controlled trial (AKIKI)

por Gaudry, Stéphane, Hajage, David, Schortgen, Fréderique, Martin-Lefevre, Laurent, Tubach, Florence, Pons, Bertrand, Boulet, Eric, Boyer, Alexandre, Lerolle, Nicolas, Chevrel, Guillaume, Carpentier, Dorothée, Lautrette, Alexandre, Bretagnol, Anne, Mayaux, Julien, Thirion, Marina, Markowicz, Philippe, Thomas, Guillemette, Dellamonica, Jean, Richecoeur, Jack, Darmon, Michael, de Prost, Nicolas, Yonis, Hodane, Megarbane, Bruno, Loubières, Yann, Blayau, Clarisse, Maizel, Julien, Zuber, Benjamin, Nseir, Saad, Bigé, Naïke, Hoffmann, Isabelle, Ricard, Jean-Damien, Dreyfuss, Didier
Publicado 2015

Can We Identify Patients with High Risk of Osteoarthritis Progression Who Will Respond to Treatment? A Focus on Biomarkers and Frailty

por Arden, Nigel, Richette, Pascal, Cooper, Cyrus, Bruyère, Olivier, Abadie, Eric, Branco, Jaime, Brandi, Maria Luisa, Berenbaum, Francis, Clerc, Cécile, Dennison, Elaine, Devogelaer, Jean-Pierre, Hochberg, Marc, D’Hooghe, Pieter, Herrero-Beaumont, Gabriel, Kanis, John A., Laslop, Andrea, Leblanc, Véronique, Maggi, Stefania, Mautone, Giuseppe, Pelletier, Jean-Pierre, Petit-Dop, Florence, Reiter-Niesert, Susanne, Rizzoli, René, Rovati, Lucio, Tajana Messi, Eleonora, Tsouderos, Yannis, Martel-Pelletier, Johanne, Reginster, Jean-Yves
Publicado 2015

Catalytic site inhibition of insulin-degrading enzyme by a small molecule induces glucose intolerance in mice

por Deprez-Poulain, Rebecca, Hennuyer, Nathalie, Bosc, Damien, Liang, Wenguang G., Enée, Emmanuelle, Marechal, Xavier, Charton, Julie, Totobenazara, Jane, Berte, Gonzague, Jahklal, Jouda, Verdelet, Tristan, Dumont, Julie, Dassonneville, Sandrine, Woitrain, Eloise, Gauriot, Marion, Paquet, Charlotte, Duplan, Isabelle, Hermant, Paul, Cantrelle, François- Xavier, Sevin, Emmanuel, Culot, Maxime, Landry, Valerie, Herledan, Adrien, Piveteau, Catherine, Lippens, Guy, Leroux, Florence, Tang, Wei-Jen, van Endert, Peter, Staels, Bart, Deprez, Benoit
Publicado 2015

Pim kinases modulate resistance to FLT3 tyrosine kinase inhibitors in FLT3-ITD acute myeloid leukemia

por Green, Alexa S., Maciel, Thiago T., Hospital, Marie-Anne, Yin, Chae, Mazed, Fetta, Townsend, Elizabeth C., Pilorge, Sylvain, Lambert, Mireille, Paubelle, Etienne, Jacquel, Arnaud, Zylbersztejn, Florence, Decroocq, Justine, Poulain, Laury, Sujobert, Pierre, Jacque, Nathalie, Adam, Kevin, So, Jason C. C., Kosmider, Olivier, Auberger, Patrick, Hermine, Olivier, Weinstock, David M., Lacombe, Catherine, Mayeux, Patrick, Vanasse, Gary J., Leung, Anskar Y., Moura, Ivan C., Bouscary, Didier, Tamburini, Jerome
Publicado 2015

Disentangling the effects of type 2 diabetes and metformin on the human gut microbiota

por Forslund, Kristoffer, Hildebrand, Falk, Nielsen, Trine, Falony, Gwen, Le Chatelier, Emmanuelle, Sunagawa, Shinichi, Prifti, Edi, Vieira-Silva, Sara, Gudmundsdottir, Valborg, Pedersen, Helle K., Arumugam, Manimozhiyan, Kristiansen, Karsten, Voigt, Anita Yvonne, Vestergaard, Henrik, Hercog, Rajna, Costea, Paul Igor, Kultima, Jens Roat, Li, Junhua, Jørgensen, Torben, Levenez, Florence, Dore, Joël, Nielsen, H. Bjørn, Brunak, Søren, Raes, Jeroen, Hansen, Torben, Wang, Jun, Ehrlich, S. Dusko, Bork, Peer, Pedersen, Oluf
Publicado 2015

Phenotypic insights into ADCY5‐associated disease

por Chang, Florence C.F., Westenberger, Ana, Dale, Russell C., Smith, Martin, Pall, Hardev S., Perez‐Dueñas, Belen, Grattan‐Smith, Padraic, Ouvrier, Robert A., Mahant, Neil, Hanna, Bernadette C., Hunter, Matthew, Lawson, John A., Max, Christoph, Sachdev, Rani, Meyer, Esther, Crimmins, Dennis, Pryor, Donald, Morris, John G.L., Münchau, Alex, Grozeva, Detelina, Carss, Keren J., Raymond, Lucy, Kurian, Manju A., Klein, Christine, Fung, Victor S.C.
Publicado 2016

European multicentre double-blind placebo-controlled trial of Nilvadipine in mild-to-moderate Alzheimer's disease—the substudy protocols: NILVAD frailty; NILVAD blood and genetic b...

por Meulenbroek, Olga, O'Dwyer, Sarah, de Jong, Daan, van Spijker, Gerrita, Kennelly, Sean, Cregg, Fiona, Olde Rikkert, Marcel, Abdullah, Laila, Wallin, Anders, Walsh, Cathal, Coen, Robert, Kenny, Rose Anne, Daly, Leslie, Segurado, Ricardo, Borjesson-Hanson, Anne, Crawford, Fiona, Mullan, Michael, Lucca, Ugo, Banzi, Rita, Pasquier, Florence, Breuilh, Laetitia, Riepe, Matthias, Kalman, Janos, Molloy, William, Tsolaki, Magda, Howard, Robert, Adams, Jessica, Gaynor, Siobhan, Lawlor, Brian
Publicado 2016

MOG-IgG in NMO and related disorders: a multicenter study of 50 patients. Part 2: Epidemiology, clinical presentation, radiological and laboratory features, treatment responses, an...

por Jarius, Sven, Ruprecht, Klemens, Kleiter, Ingo, Borisow, Nadja, Asgari, Nasrin, Pitarokoili, Kalliopi, Pache, Florence, Stich, Oliver, Beume, Lena-Alexandra, Hümmert, Martin W., Ringelstein, Marius, Trebst, Corinna, Winkelmann, Alexander, Schwarz, Alexander, Buttmann, Mathias, Zimmermann, Hanna, Kuchling, Joseph, Franciotta, Diego, Capobianco, Marco, Siebert, Eberhard, Lukas, Carsten, Korporal-Kuhnke, Mirjam, Haas, Jürgen, Fechner, Kai, Brandt, Alexander U., Schanda, Kathrin, Aktas, Orhan, Paul, Friedemann, Reindl, Markus, Wildemann, Brigitte
Publicado 2016

Assessing histone demethylase inhibitors in cells: lessons learned

por Hatch, Stephanie B., Yapp, Clarence, Montenegro, Raquel C., Savitsky, Pavel, Gamble, Vicki, Tumber, Anthony, Ruda, Gian Filippo, Bavetsias, Vassilios, Fedorov, Oleg, Atrash, Butrus, Raynaud, Florence, Lanigan, Rachel, Carmichael, LeAnne, Tomlin, Kathy, Burke, Rosemary, Westaway, Susan M., Brown, Jack A., Prinjha, Rab K., Martinez, Elisabeth D., Oppermann, Udo, Schofield, Christopher J., Bountra, Chas, Kawamura, Akane, Blagg, Julian, Brennan, Paul E., Rossanese, Olivia, Müller, Susanne
Publicado 2017

Discovery of Potent, Selective, and Orally Bioavailable Small-Molecule Modulators of the Mediator Complex-Associated Kinases CDK8 and CDK19

por Mallinger, Aurélie, Schiemann, Kai, Rink, Christian, Stieber, Frank, Calderini, Michel, Crumpler, Simon, Stubbs, Mark, Adeniji-Popoola, Olajumoke, Poeschke, Oliver, Busch, Michael, Czodrowski, Paul, Musil, Djordje, Schwarz, Daniel, Ortiz-Ruiz, Maria-Jesus, Schneider, Richard, Thai, Ching, Valenti, Melanie, de Haven Brandon, Alexis, Burke, Rosemary, Workman, Paul, Dale, Trevor, Wienke, Dirk, Clarke, Paul A., Esdar, Christina, Raynaud, Florence I., Eccles, Suzanne A., Rohdich, Felix, Blagg, Julian
Publicado 2016

Recommendations for the Use of Serious Games in Neurodegenerative Disorders: 2016 Delphi Panel

por Manera, Valeria, Ben-Sadoun, Grégory, Aalbers, Teun, Agopyan, Hovannes, Askenazy, Florence, Benoit, Michel, Bensamoun, David, Bourgeois, Jérémy, Bredin, Jonathan, Bremond, Francois, Crispim-Junior, Carlos, David, Renaud, De Schutter, Bob, Ettore, Eric, Fairchild, Jennifer, Foulon, Pierre, Gazzaley, Adam, Gros, Auriane, Hun, Stéphanie, Knoefel, Frank, Olde Rikkert, Marcel, Phan Tran, Minh K., Politis, Antonios, Rigaud, Anne S., Sacco, Guillaume, Serret, Sylvie, Thümmler, Susanne, Welter, Marie L., Robert, Philippe
Publicado 2017

2015/16 seasonal vaccine effectiveness against hospitalisation with influenza A(H1N1)pdm09 and B among elderly people in Europe: results from the I-MOVE+ project

por Rondy, Marc, Larrauri, Amparo, Casado, Itziar, Alfonsi, Valeria, Pitigoi, Daniela, Launay, Odile, Syrjänen, Ritva K, Gefenaite, Giedre, Machado, Ausenda, Vučina, Vesna Višekruna, Horváth, Judith Krisztina, Paradowska-Stankiewicz, Iwona, Marbus, Sierk D, Gherasim, Alin, Díaz-González, Jorge Alberto, Rizzo, Caterina, Ivanciuc, Alina E, Galtier, Florence, Ikonen, Niina, Mickiene, Aukse, Gomez, Veronica, Kurečić Filipović, Sanja, Ferenczi, Annamária, Korcinska, Monika R, van Gageldonk-Lafeber, Rianne, Valenciano, Marta
Publicado 2017

Exploring venlafaxine pharmacokinetic variability with a phenotyping approach, a multicentric french-swiss study (MARVEL study)

por Lloret-Linares, Célia, Daali, Youssef, Chevret, Sylvie, Nieto, Isabelle, Molière, Fanny, Courtet, Philippe, Galtier, Florence, Richieri, Raphaëlle-Marie, Morange, Sophie, Llorca, Pierre-Michel, El-Hage, Wissam, Desmidt, Thomas, Haesebaert, Frédéric, Vignaud, Philippe, Holtzmann, Jerôme, Cracowski, Jean-Luc, Leboyer, Marion, Yrondi, Antoine, Calvas, Fabienne, Yon, Liova, Le Corvoisier, Philippe, Doumy, Olivier, Heron, Kyle, Montange, Damien, Davani, Siamak, Déglon, Julien, Besson, Marie, Desmeules, Jules, Haffen, Emmanuel, Bellivier, Frank
Publicado 2017