A KRAS-variant is a Biomarker of Poor Outcome, Platinum Chemotherapy Resistance and a Potential Target for Therapy in Ovarian Cancer

por Ratner, Elena S., Keane, Florence K., Lindner, Robert, Tassi, Renata A., Paranjape, Trupti, Glasgow, Michelle, Nallur, Sunitha, Deng, Yanhong, Lu, Lingeng, Steele, Linda, Sand, Sharon, Muller, Roman-Ulrich, Bignotti, Eliana, Bellone, Stefania, Boeke, Marta, Yao, Xiaopan, Pecorelli, Sergio, Ravaggi, Antonella, Katsaros, Dionyssios, Zelterman, Daniel, Cristea, Mihaela C., Yu, Herbert, Rutherford, Thomas J., Weitzel, Jeffrey N., Neuhausen, Susan L., Schwartz, Peter E., Slack, Frank J., Santin, Alessandro D., Weidhaas, Joanne B.
Publicado 2011

A selective chemical probe for exploring the role of CDK8 and CDK19 in human disease

por Dale, Trevor, Clarke, Paul A., Esdar, Christina, Waalboer, Dennis, Adeniji-Popoola, Olajumoke, Ortiz-Ruiz, Maria-Jesus, Mallinger, Aurélie, Samant, Rahul S., Czodrowski, Paul, Musil, Djordje, Schwarz, Daniel, Schneider, Klaus, Stubbs, Mark, Ewan, Ken, Fraser, Elizabeth, TePoele, Robert, Court, Will, Box, Gary, Valenti, Melanie, de Haven Brandon, Alexis, Gowan, Sharon, Rohdich, Felix, Raynaud, Florence, Schneider, Richard, Poeschke, Oliver, Blaukat, Andree, Workman, Paul, Schiemann, Kai, Eccles, Suzanne A., Wienke, Dirk, Blagg, Julian
Publicado 2015

Functional variation in allelic methylomes underscores a strong genetic contribution and reveals novel epigenetic alterations in the human epigenome

por Cheung, Warren A., Shao, Xiaojian, Morin, Andréanne, Siroux, Valérie, Kwan, Tony, Ge, Bing, Aïssi, Dylan, Chen, Lu, Vasquez, Louella, Allum, Fiona, Guénard, Frédéric, Bouzigon, Emmanuelle, Simon, Marie-Michelle, Boulier, Elodie, Redensek, Adriana, Watt, Stephen, Datta, Avik, Clarke, Laura, Flicek, Paul, Mead, Daniel, Paul, Dirk S., Beck, Stephan, Bourque, Guillaume, Lathrop, Mark, Tchernof, André, Vohl, Marie-Claude, Demenais, Florence, Pin, Isabelle, Downes, Kate, Stunnenberg, Hendrick G., Soranzo, Nicole, Pastinen, Tomi, Grundberg, Elin
Publicado 2017

Socioeconomic status and the 25 × 25 risk factors as determinants of premature mortality: a multicohort study and meta-analysis of 1·7 million men and women

por Stringhini, Silvia, Carmeli, Cristian, Jokela, Markus, Avendaño, Mauricio, Muennig, Peter, Guida, Florence, Ricceri, Fulvio, d'Errico, Angelo, Barros, Henrique, Bochud, Murielle, Chadeau-Hyam, Marc, Clavel-Chapelon, Françoise, Costa, Giuseppe, Delpierre, Cyrille, Fraga, Silvia, Goldberg, Marcel, Giles, Graham G, Krogh, Vittorio, Kelly-Irving, Michelle, Layte, Richard, Lasserre, Aurélie M, Marmot, Michael G, Preisig, Martin, Shipley, Martin J, Vollenweider, Peter, Zins, Marie, Kawachi, Ichiro, Steptoe, Andrew, Mackenbach, Johan P, Vineis, Paolo, Kivimäki, Mika
Publicado 2017

Evaluation of a melanocortin-4 receptor (MC4R) agonist (Setmelanotide) in MC4R deficiency

por Collet, Tinh-Hai, Dubern, Béatrice, Mokrosinski, Jacek, Connors, Hillori, Keogh, Julia M., Mendes de Oliveira, Edson, Henning, Elana, Poitou-Bernert, Christine, Oppert, Jean-Michel, Tounian, Patrick, Marchelli, Florence, Alili, Rohia, Le Beyec, Johanne, Pépin, Dominique, Lacorte, Jean-Marc, Gottesdiener, Andrew, Bounds, Rebecca, Sharma, Shubh, Folster, Cathy, Henderson, Bart, O'Rahilly, Stephen, Stoner, Elizabeth, Gottesdiener, Keith, Panaro, Brandon L., Cone, Roger D., Clément, Karine, Farooqi, I. Sadaf, Van der Ploeg, Lex H.T.
Publicado 2017

Rapid, inexpensive, fingerstick, whole-blood, sensitive, specific, point-of-care test for anti-Toxoplasma antibodies

por Lykins, Joseph, Li, Xuan, Levigne, Pauline, Zhou, Ying, El Bissati, Kamal, Clouser, Fatima, Wallon, Martine, Morel, Florence, Leahy, Karen, El Mansouri, Bouchra, Siddiqui, Maryam, Leong, Nicole, Michalowski, Morgan, Irwin, Erin, Goodall, Perpetua, Ismail, Mahmoud, Christmas, Monica, Adlaoui, El Bachir, Rhajaoui, Mohamed, Barkat, Amina, Cong, Hua, Begeman, Ian J., Lai, Bo Shiun, Contopoulos-Ioannidis, Despina G., Montoya, Jose G., Maldonado, Yvonne, Ramirez, Raymund, Press, Cindy, Peyron, Francois, McLeod, Rima
Publicado 2018

Correction to: Functional variation in allelic methylomes underscores a strong genetic contribution and reveals novel epigenetic alterations in the human epigenome

por Cheung, Warren A., Shao, Xiaojian, Morin, Andréanne, Siroux, Valérie, Kwan, Tony, Ge, Bing, Aïssi, Dylan, Chen, Lu, Vasquez, Louella, Allum, Fiona, Guénard, Frédéric, Bouzigon, Emmanuelle, Simon, Marie-Michelle, Boulier, Elodie, Redensek, Adriana, Watt, Stephen, Datta, Avik, Clarke, Laura, Flicek, Paul, Mead, Daniel, Paul, Dirk S., Beck, Stephan, Bourque, Guillaume, Lathrop, Mark, Tchernof, André, Vohl, Marie-Claude, Demenais, Florence, Pin, Isabelle, Downes, Kate, Stunnenberg, Hendrick G., Soranzo, Nicole, Pastinen, Tomi, Grundberg, Elin
Publicado 2019

Appraising the causal relevance of DNA methylation for risk of lung cancer

por Battram, Thomas, Richmond, Rebecca C, Baglietto, Laura, Haycock, Philip C, Perduca, Vittorio, Bojesen, Stig E, Gaunt, Tom R, Hemani, Gibran, Guida, Florence, Carreras-Torres, Robert, Hung, Rayjean, Amos, Christopher I, Freeman, Joshua R, Sandanger, Torkjel M, Nøst, Therese H, Nordestgaard, Børge G, Teschendorff, Andrew E, Polidoro, Silvia, Vineis, Paolo, Severi, Gianluca, Hodge, Allison M, Giles, Graham G, Grankvist, Kjell, Johansson, Mikael B, Johansson, Mattias, Davey Smith, George, Relton, Caroline L
Publicado 2019

Co-trimoxazole or multivitamin multimineral supplement for post-discharge outcomes after severe anaemia in African children: a randomised controlled trial

por Maitland, Kathryn, Olupot-Olupot, Peter, Kiguli, Sarah, Chagaluka, George, Alaroker, Florence, Opoka, Robert O, Mpoya, Ayub, Walsh, Kevin, Engoru, Charles, Nteziyaremye, Julius, Mallewa, Machpherson, Kennedy, Neil, Nakuya, Margaret, Namayanja, Cate, Kayaga, Julianne, Nabawanuka, Eva, Sennyondo, Tonny, Aromut, Denis, Kumwenda, Felistas, Musika, Cynthia Williams, Thomason, Margaret J, Bates, Imelda, von Hensbroek, Michael Boele, Evans, Jennifer A, Uyoga, Sophie, Williams, Thomas N, Frost, Gary, George, Elizabeth C, Gibb, Diana M, Walker, A Sarah
Publicado 2019

Comparative global epidemiology of influenza, respiratory syncytial and parainfluenza viruses, 2010–2015

por Lam, Tommy T, Tang, Julian W, Lai, Florence Y, Zaraket, Hassan, Dbaibo, Ghassan, Bialasiewicz, Seweryn, Tozer, Sarah, Heraud, Jean-Michel, Drews, Steven J, Hachette, Todd, Chan, Paul KS, Koay, Evelyn SC, Lee, Hong Kai, Tee, Kok Keng, Liu, Yang, Fraaij, Pieter LA, Jennings, Lance, Waris, Matti, Krajden, Mel, Corriveau, André, Jalal, Hamid, Nishimura, Hidekazu, Nymadawa, Pagbajabyn, Badarch, Darmaa, Watanabe, Aripuana, Kabanda, Alice, Sloots, Theo, Kok, Jen, Dwyer, Dominic E, Koopmans, Marion
Publicado 2019

Uptake, engagement, and adherence to pre-exposure prophylaxis offered after population HIV testing in rural Kenya and Uganda: 72-week interim analysis of observational data from th...

por Koss, Catherine A, Charlebois, Edwin D, Ayieko, James, Kwarisiima, Dalsone, Kabami, Jane, Balzer, Laura B, Atukunda, Mucunguzi, Mwangwa, Florence, Peng, James, Mwinike, Yusuf, Owaraganise, Asiphas, Chamie, Gabriel, Jain, Vivek, Sang, Norton, Olilo, Winter, Brown, Lillian B, Marquez, Carina, Zhang, Kevin, Ruel, Theodore D, Camlin, Carol S, Rooney, James F, Black, Douglas, Clark, Tamara D, Gandhi, Monica, Cohen, Craig R, Bukusi, Elizabeth A, Petersen, Maya L, Kamya, Moses R, Havlir, Diane V
Publicado 2020

A snapshot of the Covid-19 pandemic among pregnant women in France

por Kayem, Gilles, Lecarpentier, Edouard, Deruelle, Philippe, Bretelle, Florence, Azria, Elie, Blanc, Julie, Bohec, Caroline, Bornes, Marie, Ceccaldi, Pierre-François, Chalet, Yasmine, Chauleur, Céline, Cordier, Anne-Gael, Desbrière, Raoul, Doret, Muriel, Dreyfus, Michel, Driessen, Marine, Fermaut, Marion, Gallot, Denis, Garabédian, Charles, Huissoud, Cyril, Luton, Dominique, Morel, Olivier, Perrotin, Franck, Picone, Olivier, Rozenberg, Patrick, Sentilhes, Loïc, Sroussi, Jeremy, Vayssière, Christophe, Verspyck, Eric, Vivanti, Alexandre J., Winer, Norbert, Alessandrini, Vivien, Schmitz, Thomas
Publicado 2020

ABHD11, a new diacylglycerol lipase involved in weight gain regulation

por Escoubet, Johanna, Kenigsberg, Mireille, Derock, Murielle, Yaligara, Veeranagouda, Bock, Marie-Dominique, Roche, Sandrine, Massey, Florence, de Foucauld, Hélène, Bettembourg, Charles, Olivier, Anne, Berthemy, Antoine, Capdevielle, Joël, Legoux, Richard, Perret, Eric, Buzy, Armelle, Chardenot, Pascale, Destelle, Valérie, Leroy, Aurélie, Cahours, Christophe, Teixeira, Sandrine, Juvet, Patrick, Gauthier, Pascal, Leguet, Michaël, Rocheteau-Beaujouan, Laurence, Chatoux, Marie-Agnès, Deshayes, Willy, Clement, Margerie, Kabiri, Mostafa, Orsini, Cécile, Mikol, Vincent, Didier, Michel, Guillemot, Jean-Claude
Publicado 2020

Repurposing Vandetanib plus Everolimus for the Treatment of ACVR1-Mutant Diffuse Intrinsic Pontine Glioma

por Carvalho, Diana M., Richardson, Peter J., Olaciregui, Nagore, Stankunaite, Reda, Lavarino, Cinzia, Molinari, Valeria, Corley, Elizabeth A., Smith, Daniel P., Ruddle, Ruth, Donovan, Adam, Pal, Akos, Raynaud, Florence I., Temelso, Sara, Mackay, Alan, Overington, John P., Phelan, Anne, Sheppard, David, Mackinnon, Andrew, Zebian, Bassel, Al-Sarraj, Safa, Merve, Ashirwad, Pryce, Jeremy, Grill, Jacques, Hubank, Michael, Cruz, Ofelia, Morales La Madrid, Andres, Mueller, Sabine, Carcaboso, Angel M., Carceller, Fernando, Jones, Chris
Publicado 2022

Human Immunodeficiency Virus Continuum of Care in 11 European Union Countries at the End of 2016 Overall and by Key Population: Have We Made Progress?

por Vourli, Georgia, Noori, Teymur, Pharris, Anastasia, Porter, Kholoud, Axelsson, Maria, Begovac, Josip, Cazein, Francoise, Costagliola, Dominique, Cowan, Susan, Croxford, Sara, d’Arminio Monforte, Antonella, Delpech, Valerie, Díaz, Asunción, Girardi, Enrico, Gunsenheimer-Bartmeyer, Barbara, Hernando, Victoria, Leierer, Gisela, Lot, Florence, Nunez, Olivier, Obel, Niels, Op de Coul, Eline, Paraskeva, Dimitra, Patrinos, Stavros, Reiss, Peter, Schmid, Daniela, Sonnerborg, Anders, Suligoi, Barbara, Supervie, Virginie, van Sighem, Ard, Zangerle, Robert, Touloumi, Giota
Publicado 2020

Single-cell chromatin accessibility profiling of glioblastoma identifies an invasive cancer stem cell population associated with lower survival

por Guilhamon, Paul, Chesnelong, Charles, Kushida, Michelle M, Nikolic, Ana, Singhal, Divya, MacLeod, Graham, Madani Tonekaboni, Seyed Ali, Cavalli, Florence MG, Arlidge, Christopher, Rajakulendran, Nishani, Rastegar, Naghmeh, Hao, Xiaoguang, Hassam, Rozina, Smith, Laura J, Whetstone, Heather, Coutinho, Fiona J, Nadorp, Bettina, Ellestad, Katrina I, Luchman, H Artee, Chan, Jennifer Ai-wen, Shoichet, Molly S, Taylor, Michael D, Haibe-Kains, Benjamin, Weiss, Samuel, Angers, Stephane, Gallo, Marco, Dirks, Peter B, Lupien, Mathieu
Publicado 2021

HIV incidence after pre-exposure prophylaxis initiation among women and men at elevated HIV risk: A population-based study in rural Kenya and Uganda

por Koss, Catherine A., Havlir, Diane V., Ayieko, James, Kwarisiima, Dalsone, Kabami, Jane, Chamie, Gabriel, Atukunda, Mucunguzi, Mwinike, Yusuf, Mwangwa, Florence, Owaraganise, Asiphas, Peng, James, Olilo, Winter, Snyman, Katherine, Awuonda, Benard, Clark, Tamara D., Black, Douglas, Nugent, Joshua, Brown, Lillian B., Marquez, Carina, Okochi, Hideaki, Zhang, Kevin, Camlin, Carol S., Jain, Vivek, Gandhi, Monica, Cohen, Craig R., Bukusi, Elizabeth A., Charlebois, Edwin D., Petersen, Maya L., Kamya, Moses R., Balzer, Laura B.
Publicado 2021

Clinical and demographic pattern of chronic granulomatous disease (CGD) from a multicenter perspective: Malaysia’s experience over 26 years

por Noh, Lokman Mohd, Latiff, Amir Hamzah Abdul, Ismail, Intan Hakimah, Noah, Rahim Md, Wahab, Asrul Abdul, Hamid, Intan Juliana Abd., Ripen, Adiratna Mat, Abdullah, Nasuruddin B., Razali, Kamarul Azhar, Zainudin, Norzila, Bakon, Florence, Kok, Long Juan, Ali, Adli, Aziz, Bilkis Banu SAbd, Latif, Hasniah Abdul, Mohamad, Siti Mardhiana, Zainudeen, Zarina Thasneem, Hashim, Ilie Fadzilah, Sendut, Iean Hamzah, Nadarajaw, Thiyagar, Jamil, Faizah Mohamed, Ng, David C. E., Abidin, Mohd Azri Zainal
Publicado 2021

French recommendations for the management of systemic sclerosis

por Hachulla, Eric, Agard, Christian, Allanore, Yannick, Avouac, Jerome, Bader-Meunier, Brigitte, Belot, Alexandre, Berezne, Alice, Bouthors, Anne-Sophie, Condette-Wojtasik, Geraldine, Constans, Joël, De Groote, Pascal, Diot, Elisabeth, Dumas, Florence, Jego, Patrick, Joly, Francisca, Launay, David, Le Guern, Veronique, Le Quintrec, Janine-Sophie, Lescaille, Geraldine, Meune, Christophe, Moulin, Bruno, Nguyen, Christelle, Omeish, Nadine, Pene, Frederic, Richard, Marie-Aleth, Rochefort, Juliette, Roren, Alexandra, Sitbon, Olivier, Sobanski, Vincent, Truchetet, Marie-Elise, Mouthon, Luc
Publicado 2021

HNRNPM controls circRNA biogenesis and splicing fidelity to sustain cancer cell fitness

por Ho, Jessica SY, Di Tullio, Federico, Schwarz, Megan, Low, Diana, Incarnato, Danny, Gay, Florence, Tabaglio, Tommaso, Zhang, JingXian, Wollmann, Heike, Chen, Leilei, An, Omer, Chan, Tim Hon Man, Hall Hickman, Alexander, Zheng, Simin, Roudko, Vladimir, Chen, Sujun, Karz, Alcida, Ahmed, Musaddeque, He, Housheng Hansen, Greenbaum, Benjamin D, Oliviero, Salvatore, Serresi, Michela, Gargiulo, Gaetano, Mann, Karen M, Hernando, Eva, Mulholland, David, Marazzi, Ivan, Wee, Dave Keng Boon, Guccione, Ernesto
Publicado 2021