The Human Early-Life Exposome (HELIX): Project Rationale and Design

por Vrijheid, Martine, Slama, Rémy, Robinson, Oliver, Chatzi, Leda, Coen, Muireann, van den Hazel, Peter, Thomsen, Cathrine, Wright, John, Athersuch, Toby J., Avellana, Narcis, Basagaña, Xavier, Brochot, Celine, Bucchini, Luca, Bustamante, Mariona, Carracedo, Angel, Casas, Maribel, Estivill, Xavier, Fairley, Lesley, van Gent, Diana, Gonzalez, Juan R., Granum, Berit, Gražulevicˇiene˙, Regina, Gutzkow, Kristine B., Julvez, Jordi, Keun, Hector C., Kogevinas, Manolis, McEachan, Rosemary R.C., Meltzer, Helle Margrete, Sabidó, Eduard, Schwarze, Per E., Siroux, Valérie, Sunyer, Jordi, Want, Elizabeth J., Zeman, Florence, Nieuwenhuijsen, Mark J.
Publicado 2014

APP, PSEN1, and PSEN2 mutations in early-onset Alzheimer disease: A genetic screening study of familial and sporadic cases

por Lanoiselée, Hélène-Marie, Nicolas, Gaël, Wallon, David, Rovelet-Lecrux, Anne, Lacour, Morgane, Rousseau, Stéphane, Richard, Anne-Claire, Pasquier, Florence, Rollin-Sillaire, Adeline, Martinaud, Olivier, Quillard-Muraine, Muriel, de la Sayette, Vincent, Boutoleau-Bretonniere, Claire, Etcharry-Bouyx, Frédérique, Chauviré, Valérie, Sarazin, Marie, le Ber, Isabelle, Epelbaum, Stéphane, Jonveaux, Thérèse, Rouaud, Olivier, Ceccaldi, Mathieu, Félician, Olivier, Godefroy, Olivier, Formaglio, Maite, Croisile, Bernard, Auriacombe, Sophie, Chamard, Ludivine, Vincent, Jean-Louis, Sauvée, Mathilde, Marelli-Tosi, Cecilia, Gabelle, Audrey, Ozsancak, Canan, Pariente, Jérémie, Paquet, Claire, Hannequin, Didier, Campion, Dominique
Publicado 2017

Immunotherapies in neuromyelitis optica spectrum disorder: efficacy and predictors of response

por Stellmann, Jan-Patrick, Krumbholz, Markus, Friede, Tim, Gahlen, Anna, Borisow, Nadja, Fischer, Katrin, Hellwig, Kerstin, Pache, Florence, Ruprecht, Klemens, Havla, Joachim, Kümpfel, Tania, Aktas, Orhan, Hartung, Hans-Peter, Ringelstein, Marius, Geis, Christian, Kleinschnitz, Christoph, Berthele, Achim, Hemmer, Bernhard, Angstwurm, Klemens, Young, Kim Lea, Schuster, Simon, Stangel, Martin, Lauda, Florian, Tumani, Hayrettin, Mayer, Christoph, Zeltner, Lena, Ziemann, Ulf, Linker, Ralf Andreas, Schwab, Matthias, Marziniak, Martin, Then Bergh, Florian, Hofstadt-van Oy, Ulrich, Neuhaus, Oliver, Zettl, Uwe, Faiss, Jürgen, Wildemann, Brigitte, Paul, Friedemann, Jarius, Sven, Trebst, Corinna, Kleiter, Ingo
Publicado 2017

Cognitive and imaging markers in non-demented subjects attending a memory clinic: study design and baseline findings of the MEMENTO cohort

por Dufouil, Carole, Dubois, Bruno, Vellas, Bruno, Pasquier, Florence, Blanc, Frédéric, Hugon, Jacques, Hanon, Olivier, Dartigues, Jean-François, Harston, Sandrine, Gabelle, Audrey, Ceccaldi, Mathieu, Beauchet, Olivier, Krolak-Salmon, Pierre, David, Renaud, Rouaud, Olivier, Godefroy, Olivier, Belin, Catherine, Rouch, Isabelle, Auguste, Nicolas, Wallon, David, Benetos, Athanase, Pariente, Jérémie, Paccalin, Marc, Moreaud, Olivier, Hommet, Caroline, Sellal, François, Boutoleau-Bretonniére, Claire, Jalenques, Isabelle, Gentric, Armelle, Vandel, Pierre, Azouani, Chabha, Fillon, Ludovic, Fischer, Clara, Savarieau, Helen, Operto, Gregory, Bertin, Hugo, Chupin, Marie, Bouteloup, Vincent, Habert, Marie-Odile, Mangin, Jean-François, Chêne, Geneviève
Publicado 2017

Apheresis therapies for NMOSD attacks: A retrospective study of 207 therapeutic interventions

por Kleiter, Ingo, Gahlen, Anna, Borisow, Nadja, Fischer, Katrin, Wernecke, Klaus-Dieter, Hellwig, Kerstin, Pache, Florence, Ruprecht, Klemens, Havla, Joachim, Kümpfel, Tania, Aktas, Orhan, Hartung, Hans-Peter, Ringelstein, Marius, Geis, Christian, Kleinschnitz, Christoph, Berthele, Achim, Hemmer, Bernhard, Angstwurm, Klemens, Stellmann, Jan-Patrick, Schuster, Simon, Stangel, Martin, Lauda, Florian, Tumani, Hayrettin, Mayer, Christoph, Krumbholz, Markus, Zeltner, Lena, Ziemann, Ulf, Linker, Ralf, Schwab, Matthias, Marziniak, Martin, Then Bergh, Florian, Hofstadt-van Oy, Ulrich, Neuhaus, Oliver, Zettl, Uwe K., Faiss, Jürgen, Wildemann, Brigitte, Paul, Friedemann, Jarius, Sven, Trebst, Corinna
Publicado 2018

Safety and Differential Antibody and T-Cell Responses to the Plasmodium falciparum Sporozoite Malaria Vaccine, PfSPZ Vaccine, by Age in Tanzanian Adults, Adolescents, Children, and...

por Jongo, Said A., Church, L. W. Preston, Mtoro, Ali T., Chakravarty, Sumana, Ruben, Adam J., Swanson, Phillip A., Kassim, Kamaka R., Mpina, Maximillian, Tumbo, Anneth-Mwasi, Milando, Florence A., Qassim, Munira, Juma, Omar A., Bakari, Bakari M., Simon, Beatus, James, Eric R., Abebe, Yonas, KC, Natasha, Saverino, Elizabeth, Gondwe, Linda, Studer, Fabian, Fink, Martina, Cosi, Glenda, El-Khorazaty, Jill, Styers, David, Seder, Robert A., Schindler, Tobias, Billingsley, Peter F., Daubenberger, Claudia, Sim, B. Kim Lee, Tanner, Marcel, Richie, Thomas L., Abdulla, Salim, Hoffman, Stephen L.
Publicado 2019

Sarcomas in patients over 90: Natural history and treatment—A nationwide study over 6 years

por Basse, Clémence, Italiano, Antoine, Penel, Nicolas, Mir, Olivier, Chemin, Claire, Toulmonde, Maud, Duffaud, Florence, Le Cesne, Axel, Chevreau, Christine, Maynou, Carlos, Anract, Philippe, Gouin, François, Rios, Maria, Firmin, Nelly, Kurtz, Jean‐Emmanuel, Kerbrat, Pierre, Piperno‐Neumann, Sophie, Bertucci, François, Rosset, Philippe, Isambert, Nicolas, Bompas, Emmanuelle, Dubray‐Longeras, Pascale, Fiorenza, Fabrice, Le Maignan, Christine, Chaigneau, Loïc, Thyss, Antoine, Bouché, Olivier, Eymard, Jean‐Christophe, Delcambre Lair, Corinne, Adam, Julien, Karanian, Marie, Lebbé, Céleste, Dupré, Aurélien, Meeus, Pierre, Brahmi, Mehdi, Dufresne, Armelle, Ducimetière, Françoise, Ray‐Coquard, Isabelle, Blay, Jean‐Yves
Publicado 2019

Multi-species annotation of transcriptome and chromatin structure in domesticated animals

por Foissac, Sylvain, Djebali, Sarah, Munyard, Kylie, Vialaneix, Nathalie, Rau, Andrea, Muret, Kevin, Esquerré, Diane, Zytnicki, Matthias, Derrien, Thomas, Bardou, Philippe, Blanc, Fany, Cabau, Cédric, Crisci, Elisa, Dhorne-Pollet, Sophie, Drouet, Françoise, Faraut, Thomas, Gonzalez, Ignacio, Goubil, Adeline, Lacroix-Lamandé, Sonia, Laurent, Fabrice, Marthey, Sylvain, Marti-Marimon, Maria, Momal-Leisenring, Raphaelle, Mompart, Florence, Quéré, Pascale, Robelin, David, Cristobal, Magali San, Tosser-Klopp, Gwenola, Vincent-Naulleau, Silvia, Fabre, Stéphane, der Laan, Marie-Hélène Pinard-Van, Klopp, Christophe, Tixier-Boichard, Michèle, Acloque, Hervé, Lagarrigue, Sandrine, Giuffra, Elisabetta
Publicado 2019

Erratum: Vol. 69, No. 5

por Ahmed, Faruque, Almendares, Olivia, Belludi, Ashwin, Benowitz, Isaac, Braden, Chris, Carlson, Christina, Chiou, Howard, Clemmons, Nakia, Daigle, Dave, Desai, Meghna, Duca, Lindsey, Fischer, Marc, Ghinai, Isaac, Greene, Carolyn, Grigg, Cheri, Grills, Ardath, Grusich, Katherina, Hallowell, Benjamin, Hoff, Connor, Jacobs, Jesica, King, Bradley, MacArthur, John, Mattison, Claire, McDonald, Jason, McPherson, Tristan, Millman, Alexander, Novosad, Shannon, Pomeroy, Mary, Qualls, Noreen, Reynolds, Maryan, Rhodes, Heather, Sharma, Rajeev, Simmonds, Robert, Stewart, Rebekah, Sunenshine, Rebecca, Tenforde, Mark, Uzicanin, Amra, Verani, Jennifer, Whitehill, Florence, Wilson, Kathryn, Wortham, Jonathan
Publicado 2020

PLK1 inhibition exhibits strong anti-tumoral activity in CCND1-driven breast cancer metastases with acquired palbociclib resistance

por Montaudon, Elodie, Nikitorowicz-Buniak, Joanna, Sourd, Laura, Morisset, Ludivine, El Botty, Rania, Huguet, Léa, Dahmani, Ahmed, Painsec, Pierre, Nemati, Fariba, Vacher, Sophie, Chemlali, Walid, Masliah-Planchon, Julien, Château-Joubert, Sophie, Rega, Camilla, Leal, Mariana Ferreira, Simigdala, Nikiana, Pancholi, Sunil, Ribas, Ricardo, Nicolas, André, Meseure, Didier, Vincent-Salomon, Anne, Reyes, Cécile, Rapinat, Audrey, Gentien, David, Larcher, Thibaut, Bohec, Mylène, Baulande, Sylvain, Bernard, Virginie, Decaudin, Didier, Coussy, Florence, Le Romancer, Muriel, Dutertre, Guillaume, Tariq, Zakia, Cottu, Paul, Driouch, Keltouma, Bièche, Ivan, Martin, Lesley-Ann, Marangoni, Elisabetta
Publicado 2020

Temporal dynamics predict symptom onset and cognitive decline in familial frontotemporal dementia

por Whiteside, David J., Malpetti, Maura, Simon Jones, P., Ghosh, Boyd C. P., Coyle-Gilchrist, Ian, van Swieten, John C., Seelaar, Harro, Jiskoot, Lize, Borroni, Barbara, Sanchez-Valle, Raquel, Moreno, Fermin, Laforce, Robert, Graff, Caroline, Synofzik, Matthis, Galimberti, Daniela, Masellis, Mario, Tartaglia, Maria Carmela, Finger, Elizabeth, Vandenberghe, Rik, de Mendonça, Alexandre, Tagliavini, Fabrizio, Butler, Chris R., Santana, Isabel, Le Ber, Isabelle, Gerhard, Alexander, Ducharme, Simon, Levin, Johannes, Danek, Adrian, Otto, Markus, Sorbi, Sandro, Pasquier, Florence, Bouzigues, Arabella, Russell, Lucy L., Rohrer, Jonathan D., Rowe, James B., Rittman, Timothy
Publicado 2022

Progression of Behavioral Disturbances and Neuropsychiatric Symptoms in Patients With Genetic Frontotemporal Dementia

por Benussi, Alberto, Premi, Enrico, Gazzina, Stefano, Brattini, Chiara, Bonomi, Elisa, Alberici, Antonella, Jiskoot, Lize, van Swieten, John C., Sanchez-Valle, Raquel, Moreno, Fermin, Laforce, Robert, Graff, Caroline, Synofzik, Matthis, Galimberti, Daniela, Masellis, Mario, Tartaglia, Carmela, Rowe, James B., Finger, Elizabeth, Vandenberghe, Rik, de Mendonça, Alexandre, Tagliavini, Fabrizio, Santana, Isabel, Ducharme, Simon, Butler, Chris R., Gerhard, Alexander, Levin, Johannes, Danek, Adrian, Otto, Markus, Frisoni, Giovanni, Ghidoni, Roberta, Sorbi, Sandro, Le Ber, Isabelle, Pasquier, Florence, Peakman, Georgia, Todd, Emily, Bocchetta, Martina, Rohrer, Jonathan D., Borroni, Barbara
Publicado 2021

Management of hyperleukocytosis and impact of leukapheresis among patients with acute myeloid leukemia (AML) on short- and long-term clinical outcomes: a large, retrospective, mult...

por Stahl, Maximilian, Shallis, Rory M., Wei, Wei, Montesinos, Pau, Lengline, Etienne, Neukirchen, Judith, Bhatt, Vijaya R., Sekeres, Mikkael A., Fathi, Amir T., Konig, Heiko, Luger, Selina, Khan, Irum, Roboz, Gail J., Cluzeau, Thomas, Martínez-Cuadron, David, Raffoux, Emmanuel, Germing, Ulrich, Umakanthan, Jayadev Manikkam, Mukherjee, Sudipto, Brunner, Andrew M., Miller, Adam, McMahon, Christine M., Ritchie, Ellen K., Rodríguez-Veiga, Rebeca, Itzykson, Raphaël, Boluda, Blanca, Rabian, Florence, Tormo, Mar, Cruz, Evelyn Acuña, Rabinovich, Emma, Yoo, Brendan, Cano, Isabel, Podoltsev, Nikolai A, Bewersdorf, Jan Philipp, Gore, Steven, Zeidan, Amer M.
Publicado 2020

Determinants of the access to remote specialised services provided by national sarcoma reference centres

por Fayet, Yohan, Tétreau, Raphaël, Honoré, Charles, Le Nail, Louis-Romée, Dalban, Cécile, Gouin, François, Causeret, Sylvain, Piperno-Neumann, Sophie, Mathoulin-Pelissier, Simone, Karanian, Marie, Italiano, Antoine, Chaigneau, Loïc, Gantzer, Justine, Bertucci, François, Ropars, Mickael, Saada-Bouzid, Esma, Cordoba, Abel, Ruzic, Jean-Christophe, Varatharajah, Sharmini, Ducimetière, Françoise, Chabaud, Sylvie, Dubray-Longeras, Pascale, Fiorenza, Fabrice, De Percin, Sixtine, Lebbé, Céleste, Soibinet, Pauline, Michelin, Paul, Rios, Maria, Farsi, Fadila, Penel, Nicolas, Bompas, Emmanuelle, Duffaud, Florence, Chevreau, Christine, Le Cesne, Axel, Blay, Jean-Yves, Le Loarer, François, Ray-Coquard, Isabelle
Publicado 2021

Improved Binding Affinity and Pharmacokinetics Enable Sustained Degradation of BCL6 In Vivo

por Huckvale, Rosemary, Harnden, Alice C., Cheung, Kwai-Ming J., Pierrat, Olivier A., Talbot, Rachel, Box, Gary M., Henley, Alan T., de Haven Brandon, Alexis K., Hallsworth, Albert E., Bright, Michael D., Akpinar, Hafize Aysin, Miller, Daniel S. J., Tarantino, Dalia, Gowan, Sharon, Hayes, Angela, Gunnell, Emma A., Brennan, Alfie, Davis, Owen A., Johnson, Louise D., de Klerk, Selby, McAndrew, Craig, Le Bihan, Yann-Vaï, Meniconi, Mirco, Burke, Rosemary, Kirkin, Vladimir, van Montfort, Rob L. M., Raynaud, Florence I., Rossanese, Olivia W., Bellenie, Benjamin R., Hoelder, Swen
Publicado 2022

Differential impairment of cerebrospinal fluid synaptic biomarkers in the genetic forms of frontotemporal dementia

por Sogorb-Esteve, Aitana, Nilsson, Johanna, Swift, Imogen J., Heller, Carolin, Bocchetta, Martina, Russell, Lucy L., Peakman, Georgia, Convery, Rhian S., van Swieten, John C., Seelaar, Harro, Borroni, Barbara, Galimberti, Daniela, Sanchez-Valle, Raquel, Laforce, Robert, Moreno, Fermin, Synofzik, Matthis, Graff, Caroline, Masellis, Mario, Tartaglia, Maria Carmela, Rowe, James B., Vandenberghe, Rik, Finger, Elizabeth, Tagliavini, Fabrizio, Santana, Isabel, Butler, Chris R., Ducharme, Simon, Gerhard, Alexander, Danek, Adrian, Levin, Johannes, Otto, Markus, Sorbi, Sandro, Le Ber, Isabelle, Pasquier, Florence, Gobom, Johan, Brinkmalm, Ann, Blennow, Kaj, Zetterberg, Henrik, Rohrer, Jonathan D.
Publicado 2022

Discovering cell-active BCL6 inhibitors: effectively combining biochemical HTS with multiple biophysical techniques, X-ray crystallography and cell-based assays

por Pierrat, Olivier A., Liu, Manjuan, Collie, Gavin W., Shetty, Kartika, Rodrigues, Matthew J., Le Bihan, Yann-Vaï, Gunnell, Emma A., McAndrew, P. Craig, Stubbs, Mark, Rowlands, Martin G., Yahya, Norhakim, Shehu, Erald, Talbot, Rachel, Pickard, Lisa, Bellenie, Benjamin R., Cheung, Kwai-Ming J., Drouin, Ludovic, Innocenti, Paolo, Woodward, Hannah, Davis, Owen A., Lloyd, Matthew G., Varela, Ana, Huckvale, Rosemary, Broccatelli, Fabio, Carter, Michael, Galiwango, David, Hayes, Angela, Raynaud, Florence I., Bryant, Christopher, Whittaker, Steven, Rossanese, Olivia W., Hoelder, Swen, Burke, Rosemary, van Montfort, Rob L. M.
Publicado 2022

ESPNIC clinical practice guidelines: intravenous maintenance fluid therapy in acute and critically ill children— a systematic review and meta-analysis

por Brossier, David W., Tume, Lyvonne N., Briant, Anais R., Jotterand Chaparro, Corinne, Moullet, Clémence, Rooze, Shancy, Verbruggen, Sascha C. A. T., Marino, Luise V., Alsohime, Fahad, Beldjilali, Sophie, Chiusolo, Fabrizio, Costa, Leonardo, Didier, Capucine, Ilia, Stavroula, Joram, Nyandat L., Kneyber, Martin C. J., Kühlwein, Eva, Lopez, Jorge, López-Herce, Jesus, Mayberry, Huw F., Mehmeti, Fortesa, Mierzewska-Schmidt, Magdalena, Miñambres Rodríguez, Maria, Morice, Claire, Pappachan, John V., Porcheret, Florence, Reis Boto, Leonor, Schlapbach, Luregn J., Tekguc, Hakan, Tziouvas, Konstantinos, Parienti, Jean-Jacques, Goyer, Isabelle, Valla, Frederic V.
Publicado 2022

APOE ε2 resilience for Alzheimer's disease is mediated by plasma lipid species: Analysis of three independent cohort studies

por Wang, Tingting, Huynh, Kevin, Giles, Corey, Mellett, Natalie A, Duong, Thy, Nguyen, Anh, Lim, Wei Ling Florence, Smith, Alex AT, Olshansky, Gavriel, Cadby, Gemma, Hung, Joseph, Hui, Jennie, Beilby, John, Watts, Gerald F, Chatterjee, Pratishtha, Martins, Ian, Laws, Simon M, Bush, Ashley I, Rowe, Christopher C, Villemagne, Victor L, Ames, David, Masters, Colin L, Taddei, Kevin, Doré, Vincent, Fripp, Jürgen, Arnold, Matthias, Kastenmüller, Gabi, Nho, Kwangsik, Saykin, Andrew J, Baillie, Rebecca, Han, Xianlin, Martins, Ralph N, Moses, Eric K, Kaddurah‐Daouk, Rima, Meikle, Peter J
Publicado 2022

Correction: ESPNIC clinical practice guidelines: intravenous maintenance fluid therapy in acute and critically ill children—a systematic review and meta-analysis

por Brossier, David W., Tume, Lyvonne N., Briant, Anais R., Jotterand Chaparro, Corinne, Moullet, Clémence, Rooze, Shancy, Verbruggen, Sascha C. A. T., Marino, Luise V., Alsohime, Fahad, Beldjilali, Sophie, Chiusolo, Fabrizio, Costa, Leonardo, Didier, Capucine, Ilia, Stavroula, Joram, Nyandat L., Kneyber, Martin C. J., Kühlwein, Eva, Lopez, Jorge, López-Herce, Jesus, Mayberry, Huw F., Mehmeti, Fortesa, Mierzewska-Schmidt, Magdalena, Miñambres Rodríguez, Maria, Morice, Claire, Pappachan, John V., Porcheret, Florence, Reis Boto, Leonor, Schlapbach, Luregn J., Tekguc, Hakan, Tziouvas, Konstantinos, Parienti, Jean-Jacques, Goyer, Isabelle, Valla, Frederic V.
Publicado 2022