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861por Wilhelm, Alexander, Widera, Marek, Grikscheit, Katharina, Toptan, Tuna, Schenk, Barbara, Pallas, Christiane, Metzler, Melinda, Kohmer, Niko, Hoehl, Sebastian, Marschalek, Rolf, Herrmann, Eva, Helfritz, Fabian A., Wolf, Timo, Goetsch, Udo, Ciesek, Sandra“…FUNDING: This study was supported in part by the Goethe-Corona-Fund of the Goethe University Frankfurt (M.W.) and the Federal Ministry of Education and Research (COVIDready; grant 02WRS1621C (M.W.).…”
Publicado 2022
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862por Gutmann, Desireé, Scheuch, Gerhard, Lehmkühler, Timon, Herrlich, Laura-Sabine, Landeis, Anton, Hutter, Martin, Stephan, Christoph, Vehreschild, Maria, Khodamoradi, Yascha, Gossmann, Ann-Kathrin, King, Florian, Weis, Frederik, Weiss, Maximilian, Rabenau, Holger F., Graf, Juergen, Donath, Helena, Schubert, Ralf, Zielen, Stefan“…DESIGN: A prospective observational cohort study in 288 adults, comprising 64 patients testing positive by SARS CoV-2 PCR before enrollment, and 224 healthy adults testing negative (matched control sample) at the University Hospital Frankfurt, Germany, from February to June 2021. Study objective was to evaluate the concentration of exhaled aerosols during physiologic breathing in SARS-CoV-2 PCR-positive and -negative subjects. …”
Publicado 2023
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863por Kattih, Badder, Operhalski, Felix, Boeckling, Felicitas, Hecker, Florian, Michael, Felix, Vamos, Mate, Hohnloser, Stefan H., Erath, Julia W.“…METHODS: The study cohort comprised a total of 119 ICD patients who underwent either S-ICD (n = 35) or TV-ICD (n = 84) implantation at the University Hospital Frankfurt from 2009 to 2017. By applying an inverse probability-weighting (IPW) analysis based on the propensity score including the Charlson Comorbidity Index (CCI) to adjust for potential extracardiac comorbidities, we aimed for head-to-head comparison on the study composite endpoint: overall survival, hospitalization, and device-associated events (including appropriate and inappropriate shocks or system-related complications). …”
Publicado 2022
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864“…To obtain an overview of the spectrum of respiratory viruses encountered in autoptical routine case work, and their infectivity, all autopsy cases at the Institute of Legal Medicine in Frankfurt/M. with flu-like symptoms (among others) were examined for at least 16 different viruses via multiplex PCR and cell culture. …”
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865“…The orientation angles of infraorbital foramen were 48.31° in the horizontal plane, 34.07° in the Frankfurt plane, and 14.4° in the parasagittal plane. …”
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866por Kochmann, Judith, Laier, Melanie, Klimpel, Sven, Wick, Arne, Kunkel, Uwe, Oehlmann, Jörg, Jourdan, Jonas“…Here, we compared infections of Gammarus roeselii with two species of Acanthocephala, Pomphorhynchus laevis, and Polymorphus minutus, along a pollution gradient in the Rhine-Main metropolitan region of Frankfurt am Main, Germany. Prevalence of P. laevis was very low at the unpolluted upstream reaches (P ≤ 3%), while higher prevalence (P ≤ 73%) and intensities of up to 9 individuals were found further downstream—close to an effluent of a large wastewater treatment plant (WWTP). …”
Publicado 2023
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867“…SETTING: A single-centre study at the non-surgical ICU of the University Hospital of Frankfurt, Germany (tertiary care-level centre). PARTICIPANTS: All cases of critically ill adult patients in need of mechanical ventilation during the years 2013–2015 were included. …”
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868por Bauer, Kristina, Rosenow, Felix, Knake, Susanne, Willems, Laurent M., Kämppi, Leena, Strzelczyk, Adam“…METHODS: In this retrospective, multicenter study, we reviewed recurrent SE patient data covering 2011 to 2017 from the university hospitals of Frankfurt and Marburg, Germany. Clinical characteristics and outcome variables were compared among the first and subsequent SE episodes using a standardized form for data collection. …”
Publicado 2023
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869por Arndt, Stephan, Wex, Cora, Häusler-Pliske, Inken, Jechorek, Dörthe, Krause, Hardy, Halloul, Zuhir, Meyer, Frank“…. – Therapy: Laparoscopic CCE including careful exploration of upper abdominal cavity for KMS manifestation (with no revision of bile duct) and peritoneal adhesiolysis (histological finding, chronic fibrosing cholecystitis with thickening of the wall of the gall bladder but no hint of malignancy) under perioperative prophylaxis with antibiotics and temporary cessation of platelet medication for 7 d preoperatively, “bridging” with low molecular weight heparin (Clexane, 1 × 40 mg s.c.; Sanofi-Aventis, Frankfurt/Main, Germany); 1 h preoperatively, 15–20 mg/kg body weight Cyclocapron i.v. …”
Publicado 2023
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870por Jennewein, Lukas, Kielland-Kaisen, Ulrikke, Paul, Bettina, Möllmann, Charlotte J., Klemt, Anna-Sophia, Schulze, Sally, Bock, Nina, Schaarschmidt, Wiebke, Brüggmann, Dörthe, Louwen, Frank“…SAMPLE: All vaginal intended deliveries out of a breech position of newborns weighing between 2.5 kg and 4.5 kg at the Obstetrics department at Goethe University Hospital Frankfurt from January 2004 until December 2016 METHODS: Neonatal and maternal outcome of a light weight group (LWG) (< 3.8 kg) was compared to and a high weight group (HWG) (≥ 3.8 kg) using Pearson’s Chi Square test and Fishers exact test. …”
Publicado 2018
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871por Burke, Michael J., Salzer, Wanda L., Devidas, Meenakshi, Dai, Yunfeng, Gore, Lia, Hilden, Joanne M., Larsen, Eric, Rabin, Karen R., Zweidler-McKay, Patrick A., Borowitz, Michael J., Wood, Brent, Heerema, Nyla A., Carroll, Andrew J., Winick, Naomi, Carroll, William L., Raetz, Elizabeth A., Loh, Mignon L., Hunger, Stephen P.“…The AALL1131 trial was designed to determine, in a randomized fashion, whether substitution with cyclophosphamide/etoposide (experimental arm 1) would improve the 4-year disease-free survival of children, adolescents, and young adults with very high-risk B-cell acute lymphoblastic leukemia compared to a modified Berlin-Frankfurt-Münster regimen (control arm). Patients 1-30 years of age with newly diagnosed very high-risk B-cell acute lymphoblastic leukemia were randomized after induction in a 1:2 fashion to the control arm or experimental arm 1 in which they were given cyclophosphamide (440 mg/m(2) days 1-5)/etoposide (100 mg/m(2) days 1-5) during part 2 of consolidation and delayed intensification. …”
Publicado 2019
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872por Kroll, Mirko, Kaupat-Bleckmann, Kirsten, Mörickel, Anja, Altenl, Julia, Schewel, Denis M., Stanullal, Martin, Zimmermann, Martin, Schrappe, Martin, Cario, Gunnar“…We analyzed seven MTX-associated toxicities during consolidation therapy in 103 DS- and 1,109 non-DS-patients (NDS) with ALL (NDS-ALL) enrolled in ALL-Berlin–Frankfurt–Münster (ALL-BFM) trials between 1995–2016 and 1995–2007, respectively. …”
Publicado 2020
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873por Adaniya, Agustina, Bazterrechea, Pablo, Trucco, José Ignacio, Schlaen, Bernardo Ariel, Kusminsky, Gustavo, Saravia, Mario Joaquin“…OBSERVATIONS: We present the case of a 20-year-old patient, diagnosed with a high-risk phy-negative, pre-B acute lymphoblastic leukemia (ALL), with a positive MLL gene rearrangement. After a Berlin-Frankfurt-Munster-like regimen chemotherapy protocol and a first complete remission, ALL relapse was diagnosed, so he was commenced on a FlaG-Ida protocol (fludarabine, idarubicin, granulocyte-colony stimulating factor, and high-dose cytarabine). …”
Publicado 2020
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874por Cario, Gunnar, Leoni, Veronica, Conter, Valentino, Attarbaschi, Andishe, Zaliova, Marketa, Sramkova, Lucie, Cazzaniga, Gianni, Fazio, Grazia, Sutton, Rosemary, Elitzur, Sarah, Izraeli, Shai, Lauten, Melchior, Locatelli, Franco, Basso, Giuseppe, Buldini, Barbara, Bergmann, Anke K., Lentes, Jana, Steinemann, Doris, Göhring, Gudrun, Schlegelberger, Brigitte, Haas, Oskar A., Schewe, Denis, Buchmann, Swantje, Moericke, Anja, White, Deborah, Revesz, Tamas, Stanulla, Martin, Mann, Georg, Bodmer, Nicole, Arad-Cohen, Nira, Zuna, Jan, Valsecchi, Maria Grazia, Zimmermann, Martin, Schrappe, Martin, Biondi, Andrea“…We analyzed clinical characteristics and outcome of 46 ABL-class fusion positive cases other than BCR-ABL1 treated according to AIEOP-BFM (Associazione Italiana di Ematologia-Oncologia Pediatrica-Berlin-Frankfurt-Münster) ALL 2000 and 2009 protocols; 13 of them received a tyrosine kinase inhibitor (TKI) during different phases of treatment. …”
Publicado 2020
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875por Brnic, Darko, Martinovic, Dinko, Zivkovic, Piero Marin, Tokic, Daria, Vilovic, Marino, Rusic, Doris, Tadin Hadjina, Ivana, Libers, Christian, Glumac, Sandro, Supe-Domic, Daniela, Tonkic, Ante, Bozic, Josko“…Plasma dp-ucMGP levels were analyzed from blood samples by CLIA method using IDS-iSYS InaKtif MGP (Immunodiagnostic Systems, Frankfurt, Germany) according to the manufacturer's instructions. fecal calprotectin (FC) levels were determined from stool samples by turbidimetric immunoassay method using Bühlmann fecal calprotectin turbo assay (Bühlmann Laboratories Aktiengesellschaft, Schonenbuch, Switzerland). …”
Publicado 2020
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876por Seifert, Lukas B., Herrera-Vizcaino, Carlos, Herguth, Philipp, Sterz, Jasmina, Sader, Robert“…The participants were fourth-year dental students from University Goethe in Frankfurt. The students were assigned to one of the three feedback methods (n = 20 per group) using simple randomization. …”
Publicado 2020
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877por Jung, Mareike, Schieck, Maximilian, Hofmann, Winfried, Tauscher, Marcel, Lentes, Jana, Bergmann, Anke, Stelter, Marie, Möricke, Anja, Alten, Julia, Schlegelberger, Brigitte, Schrappe, Martin, Zimmermann, Martin, Stanulla, Martin, Cario, Gunnar, Steinemann, Doris“…Our aim was to determine the frequency of PAX5 (P80R) in childhood BCP‐ALL treated according to the Associazione Italiana Ematologia ed Oncologia Pediatrica‐Berlin‐Frankfurt‐Muenster (AIEOP‐BFM) ALL 2000 protocol and to evaluate its clinical significance within this study cohort. …”
Publicado 2020
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878por Horn, Tabea, Ludwig, Michael, Eickmeier, Olaf, Neerinex, Anne H., Maitland-van der Zee, Anke H., Smaczny, Christina, Wagner, Thomas O. F., Schubert, Ralf, Zielen, Stefan, Majoor, Christof, Bos, Lieuwe D., Schmitt-Grohé, Sabina“…METHODS: One-hundred-and-sixteen homozygous F508del patients (mean age 27 years, m/f 66/50) were recruited from the CF centers of Bonn, Frankfurt, and Amsterdam. Sequence analysis was performed for GJA1 and GJA4. …”
Publicado 2020
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879por Kroczka, Slawomir, Stepien, Konrad, Witek-Motyl, Izabela, Klekawka, Tomasz, Kapusta, Eryk, Biedron, Agnieszka, Skorek, Pawel, Twardowska, Hanna, Stasik, Klaudia, Skoczen, Szymon“…Patients were treated with New York (NY, n = 45), previous modified Berlin–Frankfurt–Münster (pBFM, n = 64), and BFM95 (n = 106) protocols. …”
Publicado 2021
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880por Dootz, Felix, von Stackelberg, Otto-Magnus, Abaya, Joan, Jacobi, Christian, Mohs, Christoph, Craemer, Eva Maria, Rangger, Christoph, Meyding-Lamadé, Uta, Lamadé, Eva Kathrin“…METHODS: This retrospective study analyzed records of 78 Libyan patients admitted from July 2016 to November 2017 to neurological and trauma surgical departments of Krankenhaus Nordwest, Frankfurt, Germany. Issues of system preparation of the hospital, demographics, injury patterns and therapies were analyzed. …”
Publicado 2021
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