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  1. 5741
    “…RESEARCH QUESTION: How have hospitals’ emergency responses to the pandemic influenced the well-being of frontline intensivists, and do any potential strategies exist to improve their well-being and to help preserve the critical care workforce? …”
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    The Influence of the COVID-19 Pandemic on Intensivists’ Well-Being: A Qualitative Study
  2. 5742
    “…OBJECTIVE: This study aims to better understand the perspective of the clinical team (both frontline clinicians and those in administrative positions) on the implementation and normalization of TM for complex patients in a nurse-led clinic model. …”
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    Normalizing Telemonitoring in Nurse-Led Care Models for Complex Chronic Patient Populations: Case Study
  3. 5743
    “…The models developed herein can inform frontline clinicians and healthcare policymakers to manage and optimally allocate limited hospital resources to seriously ill COVID-19 patients.…”
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    Predictive modeling for COVID-19 readmission risk using machine learning algorithms
  4. 5744
    “…CONCLUSIONS: Antidepressants and benzodiazepines were frequently prescribed to treat bipolar disorder despite guidelines recommending against use as frontline therapy. These results highlight the considerable heterogeneity in care and suggest that many clinicians treating bipolar disorder are not using evidence-based prescribing practices. …”
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    Treatment Patterns Among Patients with Bipolar Disorder in the United States: A Retrospective Claims Database Analysis
  5. 5745
    “…CONCLUSIONS: For success, lifestyle programmes such as DCEP, need time and diligence to build and maintain networks and trust. Beyond frontline delivery staff and target populations, relationships should extend to local healthcare organisations and communities. …”
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    Implementation of the Diabetes Community Exercise and Education Programme (DCEP) for the management of type 2 diabetes: qualitative process evaluation
  6. 5746
    “…The fms-like tyrosine kinase 3 (FLT3) inhibitor gilteritinib is indicated for relapsed or refractory (R/R) FLT3-mutated acute myeloid leukemia (AML), based on its observed superior response and survival outcomes compared with salvage chemotherapy (SC). Frontline use of FLT3 tyrosine kinase inhibitors (TKIs) midostaurin and sorafenib may contribute to cross-resistance to single-agent gilteritinib in the R/R AML setting but has not been well characterized. …”
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    Clinical outcomes in patients with relapsed/refractory FLT3-mutated acute myeloid leukemia treated with gilteritinib who received prior midostaurin or sorafenib
  7. 5747
    “…While previous studies focused on individual-level factors, our study demonstrates the equal importance of contextual and vaccine-specific influences, especially the communication and media environment, influential leaders, sociodemographic factors, and frontline health workers.…”
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    Understanding determinants of vaccine hesitancy and acceptance in India: A qualitative study of government officials and civil society stakeholders
  8. 5748
    “…Understanding factors that influence PPE use among EMS personnel, particularly during times of public health emergencies, is essential to mitigate exposure and ensure the safety of frontline responders.…”
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    Factors Influencing Use of Personal Protective Equipment Among Emergency Medical Services Responders During the COVID-19 Pandemic: A Retrospective Chart Review
  9. 5749
    “…Regression analysis highlighted that women vs. men, nurses vs. technical/rehabilitation HW, frontline vs. second-line workers and languishing vs. moderately mentally healthy HW were more likely to receive a provisional PTSD diagnosis, whereas flourishing participants were more likely not to receive it. …”
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    The relationship between post-traumatic stress and positive mental health symptoms among health workers during COVID-19 pandemic in Lombardy, Italy
  10. 5750
    “…BACKGROUND: Being on the frontline of the battle against COVID-19, nurses and nursing students have been under considerable psychological stress and pressure. …”
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    Death anxiety, moral courage, and resilience in nursing students who care for COVID-19 patients: a cross-sectional study
  11. 5751
    “…The purpose of this study was to explore the experiences of nurses involved in frontline care (COVID Centers) during the pandemic with a particular focus on professional motivation and on the development of technical-professional and personal skills. …”
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    Back to the Roots of Nursing: Qualitative Study on the Experience of Nurses in the Front Line During the COVID-19 Pandemic
  12. 5752
    “…BACKGROUND: The novel coronavirus disease 2019 (COVID-19) pandemic placed health workers at the frontline of the emergency task force response; a duty that requires professional expertise and confidence to rapidly identify and treat patients with COVID-19. …”
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    Health Care Workers’ Perceived Self-Efficacy to Manage COVID-19 Patients in Central Uganda: A Cross-Sectional Study
  13. 5753
    “…BACKGROUND: Nilotinib is a tyrosine kinase inhibitor approved by the Ministry of Food and Drug Safety for frontline and 2nd line treatment of Philadelphia chromosome-positive chronic myeloid leukemia (Ph(+) CML). …”
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    Safety and efficacy of nilotinib in adult patients with chronic myeloid leukemia: a post-marketing surveillance study in Korea
  14. 5754
    “…Since first aid is a frontline and lifesaving intervention during life-threatening situations, it is better to give attention to enhance students’ knowledge and attitude toward first aid by giving training, establishing first aid clubs, and considering first aid courses to be included in the curriculum.…”
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    Determinants of knowledge and attitude toward first aid among final year students at technical and vocational schools in Addis Ababa, Ethiopia
  15. 5755
    por Haut, Arenal G., Haut, Elliott R.
    Publicado 2022
    “…Students could gain practical frontline, clinical exposure and real-world experiences supporting the medical system during a pandemic. …”
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    COVID19 Limits on Physician Shadowing Harm Undergraduate Students’ Futures
  16. 5756
    “…BACKGROUND: In New Zealand, 34% of deaths occur in the hospital setting where junior doctors are at the frontline of patient care. The death rate in New Zealand is expected to double by 2068 due to the aging population, but many studies report that graduates feel unprepared to care for people near the end of life and find this to be one of the most stressful parts of their work. …”
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    Palliative and end of life care in undergraduate medical education: a survey of New Zealand medical schools
  17. 5757
    “…Because, the emergency unit is at the frontline of disaster/emergency response system and helps as initial point to the most proper care of causalities, health professionals who are working in this area are the first caregivers, main players, and upfront role in calamity responses after pre-hospital medical services to disaster victims. …”
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    Knowledge, attitude, and practice of health professionals working in emergency units towards disaster and emergency preparedness in South Gondar Zone hospitals, Ethiopia, 2020
  18. 5758
    “…Intestinal intraepithelial lymphocytes (IELs) are distributed along the length of the intestine and are considered the frontline of immune surveillance. The precise molecular mechanisms, especially epigenetic regulation, of their development and function are poorly understood. …”
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    The histone demethylase Kdm6b regulates the maturation and cytotoxicity of TCRαβ(+)CD8αα(+) intestinal intraepithelial lymphocytes
  19. 5759
    “…Tissue from patients enrolled in the randomized double-blind trial of Vigil vs. placebo as maintenance in frontline management of advanced resectable ovarian cancer underwent DNA polymorphism analysis. …”
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    Network based analysis identifies TP53m-BRCA1/2wt-homologous recombination proficient (HRP) population with enhanced susceptibility to Vigil immunotherapy
  20. 5760
    “…CONCLUSION: The incidence of de novo T790M is low. Osimertinib in frontline therapy provides promising outcomes.…”
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    Treatment pattern and outcomes in de novo T790M-mutated non-small cell lung cancer
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