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  1. 5901
    “…Knowledge of the status of these mutations in AML patients not only guides treatment decisions but also helps in predicting response to frontline induction and consolidation chemotherapy as well as the risk of relapse and overall survival. …”
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    Clinico-Haematologic association and prognostic relevance of NPM1 and FLT3-ITD mutations in acute Myeloid Leukaemia
  2. 5902
    “…CONCLUSIONS: Designating practice coordinators to lead their peers in simulator-based practice led to more consistent skills practice within frontline health facilities. Ongoing support, scheduling of practice sessions, and assessment and communication of motivation factors may help sustain LDHF practice and similar forms of continuing professional development. …”
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    “Practice so that the skill does not disappear”: mixed methods evaluation of simulator-based learning for midwives in Uganda
  3. 5903
    “…BACKGROUND: Despite the increasing frequency of ARV medicines stock-outs in Sub-Saharan Africa, there is little research inquiring into the mitigation strategies devised by frontline health facilities. Many previous studies have focused on ‘upstream’ or national-level drivers of ARVs stock-outs with less empirical attention devoted ‘down-stream’ or at the facility-level. …”
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    “The number of clients is increasing but the supplies are reducing”: provider strategies for responding to chronic antiretroviral (ARV) medicines stock-outs in resource-limited settings: a qualitative study from Uganda
  4. 5904
    “…METHODS: Thirty cats were randomized to three equal groups: (A) untreated controls; (B) to receive a single application of fluralaner plus moxidectin (Bravecto(®) Plus) at 40 mg/kg and 2 mg/kg body weight, respectively; and (C) three applications at one month intervals with a spot-on formulation of fipronil and (S)-methoprene (Frontline(®) Plus) at 0.5 ml manufacturer recommended dose. …”
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    Efficacy of a spot-on combination of fluralaner plus moxidectin (Bravecto(®) Plus) in cats following repeated experimental challenge with a field isolate of Ctenocephalides felis
  5. 5905
    “…BACKGROUND: In healthcare settings, system and organization leaders often control the selection and design of implementation strategies even though frontline workers may have the most intimate understanding of the care delivery process, and factors that optimize and constrain evidence-based practice implementation within the local system. …”
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    The clinician crowdsourcing challenge: using participatory design to seed implementation strategies
  6. 5906
    “…Encouraging health care professionals in such settings to recommend BSS as frontline treatment for adults with diarrhea, and promoting BSS for diarrhea self-management, may reduce antibiotic use and rates of antibiotic resistance globally. …”
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    Effect of Bismuth Subsalicylate vs Placebo on Use of Antibiotics Among Adult Outpatients With Diarrhea in Pakistan: A Randomized Clinical Trial
  7. 5907
    “…Of the 10 million cases of tuberculosis in 2017, approximately 19% of new cases and 43% of previously treated cases were caused by strains of M. tuberculosis resistant to at least one frontline antibiotic. There is a clear need for new therapies that target these genetically resistant strains. …”
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    Identification of 4-Amino-Thieno[2,3-d]Pyrimidines as QcrB Inhibitors in Mycobacterium tuberculosis
  8. 5908
    “…CONCLUSIONS: There were problems with the awareness and implementation of the CPE toolkit and frontline staff saw room for improvement, identifying implementation barriers and facilitators. …”
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    Implementing a toolkit for the prevention, management and control of carbapenemase-producing Enterobacteriaceae in English acute hospitals trusts: a qualitative evaluation
  9. 5909
    “…CONCLUSION: Despite concerns over azole resistance among Aspergillus, these agents remain frontline against invasive aspergillosis. The excellent activity of RZF and CAS shown here suggests that the drugs are potential therapeutic options for patients infected with azole BT Aspergillus, including azole-resistant isolates. …”
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    738. Potent In Vitro activity of Rezafungin (RZF) Against Aspergillus Clinical Isolates Recovered From Lung Transplant Patients Who Have Received ≥3 Months of Triazole Prophylaxis
  10. 5910
    “…Thus, a registered nurse was determined to be more cost-effective and was hired to replace the existing nurse practitioners in the frontline management of telemonitoring alerts and take over the technical support role from a telehealth analyst. …”
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    User-Centered Adaptation of an Existing Heart Failure Telemonitoring Program to Ensure Sustainability and Scalability: Qualitative Study
  11. 5911
    “…Better understanding the functional components of PHC facility management can help policymakers and frontline managers drive evidence-based improvements in performance.…”
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    Preliminary validation of the PRImary care facility Management Evaluation tool (PRIME-Tool), a national facility management survey implemented in Ghana
  12. 5912
    “…A growing body of literature supports the involvement of frontline providers, namely mid-level practitioners and community health workers, in chronic care management. …”
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    An integrated intervention for chronic care management in rural Nepal: protocol of a type 2 hybrid effectiveness-implementation study
  13. 5913
    “…We developed the intervention with, and for, frontline clinician users, using principles of human-centered design. …”
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    Evaluation of a Health Information Technology–Enabled Panel Management Platform to Improve Anticoagulation Control in a Low-Income Patient Population: Protocol for a Quasi-Experimental Design
  14. 5914
    por Diop, Fary, Moia, Riccardo, Favini, Chiara, Spaccarotella, Elisa, De Paoli, Lorenzo, Bruscaggin, Alessio, Spina, Valeria, Terzi-di-Bergamo, Lodovico, Arruga, Francesca, Tarantelli, Chiara, Deambrogi, Clara, Rasi, Silvia, Adhinaveni, Ramesh, Patriarca, Andrea, Favini, Simone, Sagiraju, Sruthi, Jabangwe, Clive, Kodipad, Ahad A., Peroni, Denise, Mauro, Francesca R., Giudice, Ilaria Del, Forconi, Francesco, Cortelezzi, Agostino, Zaja, Francesco, Bomben, Riccardo, Rossi, Francesca Maria, Visco, Carlo, Chiarenza, Annalisa, Rigolin, Gian Matteo, Marasca, Roberto, Coscia, Marta, Perbellini, Omar, Tedeschi, Alessandra, Laurenti, Luca, Motta, Marina, Donaldson, David, Weir, Phil, Mills, Ken, Thornton, Patrick, Lawless, Sarah, Bertoni, Francesco, Poeta, Giovanni Del, Cuneo, Antonio, Follenzi, Antonia, Gattei, Valter, Boldorini, Renzo Luciano, Catherwood, Mark, Deaglio, Silvia, Foà, Robin, Gaidano°, Gianluca, Rossi°, Davide
    Publicado 2020
    “…If validated, BIRC3 mutations may be used as a new molecular predictor to select high-risk patients for novel frontline therapeutic approaches.…”
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    Biological and clinical implications of BIRC3 mutations in chronic lymphocytic leukemia
  15. 5915
    “…Respondents included health workers at the following levels: regional health managers (n = 4), district health managers (n = 4), and frontline healthcare providers (n = 4). All interviews were recorded, transcribed, and thematically analyzed using qualitative content analysis. …”
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    Health workers’ perceptions and challenges in implementing meningococcal serogroup a conjugate vaccine in the routine childhood immunization schedule in Burkina Faso
  16. 5916
    “…RESULTS: Altogether, 544 trained frontline health workers involved in malaria elimination at the time of the survey were recruited and 56% (302/544) were stationed at sub-Rural Health Centers. …”
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    Do we need to go further to train healthcare providers in the targeted regions for malaria elimination in Myanmar? A mixed-methods study
  17. 5917
    “…METHODS: A total of 30 participants representing six stakeholder groups (ie, patients, family members, academic experts, frontline managers, service providers, and health care decision makers) participated in semistructured interviews. …”
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    Stakeholder Perceptions of Internet-Delivered Cognitive Behavior Therapy as a Treatment Option for Alcohol Misuse: Qualitative Analysis
  18. 5918
    “…Furthermore, EM forms a vital part of the national emergency response programme of many countries and will provide a frontline diagnostic service in the event of a bioterrorism incident, particularly in the scenario of a deliberate release of smallpox virus. …”
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    Application of transmission electron microscopy to the clinical study of viral and bacterial infections: Present and future
  19. 5919
    por Akande, Patrick Aboh
    Publicado 2020
    “…BACKGROUND: Nurses are particularly vulnerable to nosocomial tuberculosis (TB) infection because, being in the frontline of healthcare provision, they are frequently exposed to patients with infectious TB disease. …”
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    Knowledge and practices regarding tuberculosis infection control among nurses in Ibadan, south-west Nigeria: a cross-sectional study
  20. 5920
    “…At the policy level, frontline health workers distribute iron supplements to pregnant women only and do not follow up on adherence. …”
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    Moving beyond individual barriers and identifying multi-level strategies to reduce anemia in Odisha India
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