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  1. 6361
    “…BACKGROUND: A multidrug-resistant co-lineage of Plasmodium falciparum malaria, named KEL1/PLA1, spread across Cambodia in 2008–13, causing high rates of treatment failure with the frontline combination therapy dihydroartemisinin-piperaquine. …”
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    Evolution and expansion of multidrug-resistant malaria in southeast Asia: a genomic epidemiology study
  2. 6362
    “…BACKGROUND: Adrenocortical carcinoma (ACC) in an aggressive malignancy with suboptimal response to frontline chemotherapy and without established second line treatment. cMET activation is associated with ACC resistance to chemotherapy. …”
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    SAT-175 Trial in Progress Interim Report: A Phase II Clinical Trial Using Single Agent Cabozantinib in Advanced Adrenocortical Carcinoma
  3. 6363
    “…METHODS: We retrospectively reviewed patients with FLT3-mutated AML between November 2006 and December 2019. RESULTS: In frontline patients treated with a FLT3i (cohort 1), the CRc rates and median overall survival (OS) with the first (n = 56), second (n = 32), and third FLT3i-based (n = 8) therapy were 77%, 31%, and 25%, and 16.7 months, 6.0 months, and 1.4 months, respectively. …”
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    Outcomes with sequential FLT3-inhibitor-based therapies in patients with AML
  4. 6364
    “…Exposure to information about positive outcomes for patients with COVID-19, development of vaccines and effective treatments, and heroic stories about frontline health care workers were associated with both better mental health and higher compliance with preventive measures. …”
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    Associations of Mental Health and Personal Preventive Measure Compliance With Exposure to COVID-19 Information During Work Resumption Following the COVID-19 Outbreak in China: Cross-Sectional Survey Study
  5. 6365
    “…The aim of this systematic review was to identify the effectiveness of the behaviour change techniques utilised in recent hand hygiene interventions that seek to improve hand hygiene compliance among nurses in hospitals in high-income countries. Nurses are at the frontline of healthcare delivery, and so improving their HH behaviour and thus increasing HHC rates will have a relatively large impact on reducing transmission and preventing healthcare acquired infections. …”
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    The effect of behavioural interventions targeting hand hygiene practices among nurses in high-income hospital settings: a systematic review
  6. 6366
    “…Opinions were obtained after the 10-week study period through a survey and facilitated group discussions between frontline HCWs and managers who had encountered the DTS during their daily work routine. …”
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    818. Healthcare Worker Feedback Regarding the Implementation of a New Disinfection Tracking System
  7. 6367
    “…RESULTS: Among the 355 videos, 154 (43.4%) related to guidance for clinicians, patients, and ordinary citizens, followed by information concerning the government’s handling of the pandemic (n=100, 28.2%), the latest news about COVID-19 (n=61, 17.2%), and appreciation toward frontline emergency services (n=40, 11.3%). Video length, titles, dialogic loop, and content type all influenced the level of citizen engagement. …”
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    Factors Driving Citizen Engagement With Government TikTok Accounts During the COVID-19 Pandemic: Model Development and Analysis
  8. 6368
    “…Yet, as few as 20% of these women are treated with frontline interventions such as evidence-based psychological treatments. …”
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    Scaling Up Maternal Mental healthcare by Increasing access to Treatment (SUMMIT) through non-specialist providers and telemedicine: a study protocol for a non-inferiority randomized controlled trial
  9. 6369
    “…Shortages of face masks and other protective equipment place health workers, already on the frontline of the disease, at higher risk. Moral distress from making difficult decisions about allocating scarce resources and care to patients ill with COVID-19 can further add to burdens health workers face. …”
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    Protecting providers and patients: results of an Internet survey of health care workers’ risk perceptions and ethical concerns during the COVID-19 pandemic
  10. 6370
    “…Policy makers should consider increasing training of frontline health workers, such as Family Welfare Visitors to provide evidence-based information about Mifepristone/Misoprostol.…”
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    Out-of-clinic and self-managed abortion in Bangladesh: menstrual regulation provider perspectives
  11. 6371
    “…Identifying barriers and enablers faced by frontline health workers recording HMIS source data in registers is important to improve data for use. …”
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    Barriers and enablers to routine register data collection for newborns and mothers: EN-BIRTH multi-country validation study
  12. 6372
    “…CONCLUSION: Identifying key clinical characteristics of COVID-19 that predict ICU admission and high mortality can be useful for frontline healthcare providers in making the right clinical decision under time-sensitive and resource-constricted environment.…”
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    Clinical features and prognostic factors of intensive and non-intensive 1014 COVID-19 patients: an experience cohort from Alahsa, Saudi Arabia
  13. 6373
    “…The virus is transmitted from an infected person to another person through close contact and droplets. Frontline health care workers are the most at risk of infection, and so a WHO interim guidance document was issued by the World Health Organization (WHO) which underscores the importance of proper sanitation and waste management practices for COVID- 19 in health-care settings. …”
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    COVID – 19 related knowledge and preventive practices early in the outbreak among health care workers in selected public health facilities of Illu aba Bor and Buno Bedelle zones, Southwest Ethiopia
  14. 6374
    por Laurent, Alexandra, Fournier, Alicia, Lheureux, Florent, Louis, Guillaume, Nseir, Saad, Jacq, Gwenaelle, Goulenok, Cyril, Muller, Grégoire, Badie, Julio, Bouhemad, Bélaïd, Georges, Marjolaine, Mertes, Paul-Michel, Merdji, Hamid, Castelain, Vincent, Abdulmalak, Caroline, Lesieur, Olivier, Plantefeve, Gaëtan, Lacherade, Jean-Claude, Rigaud, Jean-Philippe, Sedillot, Nicholas, Roux, Damien, Terzi, Nicolas, Beuret, Pascal, Monsel, Antoine, Poujol, Anne-Laure, Kuteifan, Khaldoun, Vanderlinden, Thierry, Renault, Anne, Vivet, Bérengère, Vinsonneau, Christophe, Barbar, Saber Davide, Capellier, Gilles, Dellamonica, Jean, Ehrmann, Stephan, Rimmelé, Thomas, Bohé, Julien, Bouju, Pierre, Gibot, Sébastien, Lévy, Bruno, Temime, Johanna, Pichot, Cyrille, Schnell, David, Friedman, Diane, Asfar, Pierre, Lebas, Eddy, Mateu, Philippe, Klouche, Kada, Audibert, Juliette, Ecarnot, Fiona, Meunier-Beillard, Nicolas, Loiseau, Mélanie, François-Pursell, Irène, Binquet, Christine, Quenot, Jean-Pierre
    Publicado 2021
    “…METHODS: This cross-sectional survey was conducted in 77 French hospitals from April 22 to May 13 2020. All ICU frontline healthcare workers were eligible. The primary endpoint was the mental health, assessed using the 12-item General Health Questionnaire. …”
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    Mental health and stress among ICU healthcare professionals in France according to intensity of the COVID-19 epidemic
  15. 6375
    “…Care home residents and staff, frontline health-care workers, and adults aged 80 years and older were vaccinated first. …”
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    Effectiveness of BNT162b2 and ChAdOx1 nCoV-19 COVID-19 vaccination at preventing hospitalisations in people aged at least 80 years: a test-negative, case-control study
  16. 6376
    “…To increase the utilisation of the services, the health care providers should give emphases on counselling, awareness creation, and strengthen the existing frontline integrated health care services in the country.…”
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    A multilevel analysis of determinants of PMTCT service utilisation among women during the antepartum, intrapartum and postpartum period in Ethiopia
  17. 6377
    “…First-level leaders are individuals who directly supervise and manage frontline employees who do not manage others. However, first-level leadership is underrepresented in existing reviews of the impact of leadership on EBP implementation. …”
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    The relationship between first-level leadership and inner-context and implementation outcomes in behavioral health: a scoping review
  18. 6378
    “…OBJECTIVE: The first aim of the study is to investigate frontline and management perceptions of and experiences with veteran falls as they pertain to inpatient environmental factors. …”
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    Examining the Relationship Between Environmental Factors and Inpatient Hospital Falls: Protocol for a Mixed Methods Study
  19. 6379
    “…With the rising resistance to frontline drugs (artemisinin-based combinations), there is a need to accelerate the discovery and development of newer anti-malarial drugs. …”
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    Antiplasmodial, antimalarial activities and toxicity of African medicinal plants: a systematic review of literature
  20. 6380
    “…Lockdown restrictions, physical distancing, social isolation, as well as the loss of a loved one, working in a frontline capacity and loss of economic security may have negative effects on and increase the mental health challenges in populations around the world. …”
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    Mental health in the pandemic: a repeated cross-sectional mixed-method study protocol to investigate the mental health impacts of the coronavirus pandemic in the UK
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