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Mostrando 221 - 240 Resultados de 352 Para Buscar '"Göttingen"', tiempo de consulta: 0.22s Limitar resultados
  1. 221
    “…Two series of experiments were carried out in 8 Lan-Yu and 3 Göttingen mini-pigs, respectively. A 2mm central full thickness corneal perforation was made with surgical scissors and 2mm trephines. …”
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    Use of Fish Scale-Derived BioCornea to Seal Full-Thickness Corneal Perforations in Pig Models
  2. 222
    “…In this study, we evaluated an intramuscular (IM) prime/intranasal boost vaccination strategy in a Göttingen Minipig model with a reproductive system very similar to humans. …”
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    Intramuscular Priming and Intranasal Boosting Induce Strong Genital Immunity Through Secretory IgA in Minipigs Infected with Chlamydia trachomatis
  3. 223
    “…Design, setting, and participants: A qualitative interview study. All SPs of Göttingen medical school who had been working longer than three semesters (n=14) were invited and agreed to take part in an open interview about their daily experience with real doctors. …”
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    Working as simulated patient has effects on real patient life – Preliminary insights from a qualitative study
  4. 224
    “…In the present study, we performed a phenotype‐based genetic association study (PGAS) in > 1,000 schizophrenia patients from the Göttingen Research Association for Schizophrenia (GRAS) data collection and found an association between the MMP‐9 rs20544 C/T single‐nucleotide polymorphism (SNP) located in the 3′untranslated region (UTR) and the severity of a chronic delusional syndrome. …”
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    A normal genetic variation modulates synaptic MMP‐9 protein levels and the severity of schizophrenia symptoms
  5. 225
    “…C. difficile was isolated from stool samples from infants born in two hospitals in Göttingen and Darmstadt, Germany. All isolates were subjected to phenotypic antimicrobial resistance testing, PCR-based screening for toxin genes and mass spectrometry-based exclusion of ribotypes 027 and 176. …”
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    Antimicrobial Resistance Patterns in Clostridioides difficile Strains Isolated from Neonates in Germany
  6. 226
    “…In line with this, we investigated the plasmid-resistome of seven bla(OXA-48) gene-carrying Klebsiella pneumoniae isolates, which were isolated between 2013 and 2014 at the University Medical Center in Göttingen, Germany. All isolates were subjected to complete genome sequencing including the reconstruction of entire plasmid sequences. …”
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    Detection of a New Resistance-Mediating Plasmid Chimera in a bla(OXA-48)-Positive Klebsiella pneumoniae Strain at a German University Hospital
  7. 227
    “…Uncovering the proteome changes following DEX implant intervention in CRVO may identify key proteins that mediate the beneficial effects of DEX. In six Göttingen minipigs, CRVO was induced in both eyes with an argon laser using a well-established experimental model. …”
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    Dexamethasone Intravitreal Implant Is Active at the Molecular Level Eight Weeks after Implantation in Experimental Central Retinal Vein Occlusion
  8. 228
    “…To test whether SORL1 can function as an AD causal gene, we use CRISPR-Cas9-based gene editing to develop a model of SORL1 haploinsufficiency in Göttingen minipigs, taking advantage of porcine models for biomarker investigations. …”
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    A genetically modified minipig model for Alzheimer’s disease with SORL1 haploinsufficiency
  9. 229
    por Monastyrsky, Michael I
    Publicado 2008
    “…The author, a distinguished mathematical physicist, takes into account his own research at the Riemann archives of Göttingen University and developments over the last decade that connect Riemann with numerous significant ideas and methods reflected throughout contemporary mathematics and physics. …”
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    Riemann, topology, and physics
  10. 230
    por Siegmund-Schultze, Reinhard
    Publicado 2001
    “…To help promote cooperation between physics and mathematics Rockefeller funds supported the erection of the new Mathematical Institute in Göttingen between 1926 and 1929, while the rise of probability and mathematical statistics owes much to the creation of the Institut Henri Poincaré in Paris by American philanthropy at about the same time. …”
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    Rockefeller and the internationalization of mathematics between the two world wars: document and studies for the social history of mathematics in the 20th century
  11. 231
    “…METHODS AND RESULTS: In a first approach, we pretreated anaesthetised adult Göttingen minipigs with 7 mg kg(−1) diazoxide (n = 5) or placebo (n = 5) intravenously over 10 min and subjected them to 60 min coronary occlusion and 180 min reperfusion; blood pressure was maintained by use of an aortic snare. …”
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    Diazoxide is a powerful cardioprotectant but is not feasible in a realistic infarct scenario
  12. 232
    “…Here, Collex was tested on partial thickness burn wounds in Göttingen minipigs compared to Jelonet, and a variant of Collex without HTX. …”
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    Alginate and Nanocellulose Dressings With Extract From Salmon Roe Reduce Inflammation and Accelerate Healing of Porcine Burn Wounds
  13. 233
    “…In an in-vivo study, a drill hole was made in the proximal part of the femur in 6 mature Göttingen minipigs and microdialysis was performed over 3 h. …”
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    Microdialysis in the femoral head of the minipig and in a blood cloth of human blood
  14. 234
    “…We utilized the to our knowledge worldwide largest phenotypical database of schizophrenic patients (n>1000), the GRAS (Göttingen Research Association for Schizophrenia) Data Collection. …”
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    Dissociation of accumulated genetic risk and disease severity in patients with schizophrenia
  15. 235
    “…We therefore studied the role of solvent coformulants in OP toxicity in a novel minipig model of agricultural OP poisoning. Gottingen minipigs were orally poisoned with clinically relevant doses of agricultural emulsifiable concentrate (EC) dimethoate, dimethoate active ingredient (AI) alone, or solvents. …”
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    A role for solvents in the toxicity of agricultural organophosphorus pesticides
  16. 236
    “…The adult serum concentrations of pig AGP were in the range of 1–3 mg/ml in a number of conventional pig breeds while it was lower in Göttingen and Ossabaw minipigs (in the 0.3 to 0.6 mg/ml range) and higher in young (2–5 days old) conventional pigs (mean: 6.6 mg/ml). …”
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    Pig α(1)-Acid Glycoprotein: Characterization and First Description in Any Species as a Negative Acute Phase Protein
  17. 237
    “…The resulting test included 150 items and was taken by 77 and 79 final year medical students from Göttingen and Hamburg at the beginning and the end of their practice year, respectively. …”
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    Increase in medical knowledge during the final year of undergraduate medical education in Germany
  18. 238
    “…For that purpose, the GRAS (Göttingen Research Association for Schizophrenia) data collection was initiated in 2005. …”
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    Phenotype-Based Genetic Association Studies (PGAS)—Towards Understanding the Contribution of Common Genetic Variants to Schizophrenia Subphenotypes
  19. 239
    “…The serendipitous rediscovery of the preserved historic brain specimen in the collections at Göttingen University, being mistaken as the brain of the mathematician C.F. …”
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    Revisiting a historic human brain with magnetic resonance imaging – the first description of a divided central sulcus
  20. 240
    “…Based on their complementary signalling pathways, we assessed humoral immune responses to model antigens after co-administration with the toll-like receptor 4 (TLR4) stimulator glucopyranosyl lipid adjuvant (GLA-AF) or the TLR7/8 agonist resiquimod (R848) (alone and in combination) via the intradermal (ID), intranasal (IN) or combined routes in the Gottingen minipig animal model. Surprisingly, we discovered that while GLA-AF additively enhanced the adjuvant effect of R848 when injected ID, it abrogated the adjuvant activity of R848 after IN inoculation. …”
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    TLR4 and TLR7/8 Adjuvant Combinations Generate Different Vaccine Antigen-Specific Immune Outcomes in Minipigs when Administered via the ID or IN Routes
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