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281por Theruvath, Ashok Joseph, Aghighi, Maryam, Iv, Michael, Nejadnik, Hossein, Lavezo, Jonathan, Pisani, Laura Jean, Daldrup-Link, Heike Elisabeth“…Methods: In an animal care and use committee-approved prospective case-control study, ten Göttingen minipigs received either intravenous ferumoxytol injections at a dose of 5 mg Fe/kg (n=4) or remained untreated (n=6). …”
Publicado 2020
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282por Hofmann-Winkler, Heike, Moerer, Onnen, Alt-Epping, Sabine, Bräuer, Anselm, Büttner, Benedikt, Müller, Martin, Fricke, Torben, Grundmann, Julian, Harnisch, Lars-Olav, Heise, Daniel, Kernchen, Andrea, Pressler, Meike, Stephani, Caspar, Tampe, Björn, Kaul, Artur, Gärtner, Sabine, Kramer, Stefanie, Pöhlmann, Stefan, Winkler, Martin Sebastian“…SETTING: Patient treated in ICU of University hospital Göttingen, Germany. PATIENTS: Eleven critical ill coronavirus disease 2019 patients with organ failure were treated in ICU. …”
Publicado 2020
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283por Vandamme, Katleen, Thevissen, Karin, Mesquita, Marcelo F., Coropciuc, Ruxandra‐Gabriella, Agbaje, Jimoh, Thevissen, Patrick, da Silva, Wander José, Vleugels, Jozef, De Cremer, Kaat, Gerits, Evelien, Martens, Johan A., Michiels, Jan, Cammue, Bruno P. A., Braem, Annabel“…The aim of this in vivo study was to assess the osseointegration of a titanium‐silica composite implant, previously shown to enable controlled release of therapeutic concentrations of chlorhexidine, in the Göttingen mini‐pig oral model. MATERIAL AND METHODS: Three implant groups were designed: macroporous titanium implants (Ti‐Porous); macroporous titanium implants infiltrated with mesoporous silica (Ti‐Porous + SiO(2)); and conventional titanium implants (Ti‐control). …”
Publicado 2020
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284“…We performed a total number of 24 retrograde-tunneled HDC insertions in 23 patients (requiring placement of a HDC for the temporary or permanent treatment of ESKD) admitted to our Department of Nephrology and Rheumatology at the University Medical Center Göttingen, Germany. Results: The overall success rate of applying the RASS for US-guided tip positioning of retrograde-tunneled HDCs was 24/24 (100%), with proper tip position in the right atrium in 18/23 (78.3%), or cavoatrial junction in 5/23 (21.7%) when RASS was positive and improper position when RASS was negative in 1/1 (100%), confirmed by portable anterior-posterior chest radiography, with only minor post-procedural bleeding in 2/24 (8.3%). …”
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285por Halecker, Sabrina, Metzger, Julia, Strube, Christina, Krabben, Ludwig, Kaufer, Benedikt, Denner, Joachim“…In contrast to all other minipig breeds (Göttingen minipigs, Aachen minipigs, Yucatan micropig, Massachusetts General Hospital miniature pigs), Mini-LEWE minipigs have less viruses and no PERV-A/C. …”
Publicado 2021
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286por Jiao, Hongli, Lee, Ming-Song, Sivapatham, Athillesh, Leiferman, Ellen M., Li, Wan-Ju“…In this study, we derived iPSCs from fibroblasts of Wisconsin miniature swine (WMS), Yucatan miniature swine (YMS), and Göttingen minipigs (GM) using our culture medium. By comparing cells of the different pig breeds, we found that YMS fibroblasts were more efficiently reprogrammed into iPSCs, forming colonies with well-defined borders, than WMS and GM fibroblasts. …”
Publicado 2022
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287por Juhl, Aaron Levin, Grenzer, Insa Maria, Teegen, Bianca, Wiltfang, Jens, Fitzner, Dirk, Hansen, Niels“…METHODS: We retrospectively analyzed data from 167 psychiatric patients at the University Medical Center Göttingen from 2017 to 2020. We divided this patient cohort into two, namely antibody-positive and antibody-negative. …”
Publicado 2022
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288“…In this article, we assess the impact of the learning tasks in a field study by implementing them into lecture-based recitations in a first-year electrodynamics course at the University of Göttingen. For this, a within- and between-subjects design is used comparing a multi-representational intervention group and a control group working on traditional calculation-based tasks. …”
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289por Hunniford, Victoria, Kühler, Robert, Wolf, Bettina, Keppeler, Daniel, Strenzke, Nicola, Moser, Tobias“…We distributed a questionnaire to 180 adult patients from the University Medical Center Göttingen’s Department of Otolaryngology who were actively using an eCI for 6 months or more during the time of the survey period. …”
Publicado 2023
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290por Lemmer, Boris“…Weil er schon immer wissen wollte, woraus die Welt zusammengebaut ist, entschloss er sich zu einem Physikstudium an der Justus-Liebig-Universität Gießen und promoviert zur Zeit an der Georg-August-Universität Göttingen. Er arbeitet am ATLAS-Experiment, einem der beiden großen Allzweckdetektoren am weltgrößten Teilchenbeschleuniger LHC am Forschungszentrum CERN in Genf. …”
Publicado 2014
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291por Topaz, Tom, Ben-Ari, Julius, Banchik, Evgenia Kertsnus, Bassa, Or, Egozi, Roey, Suari, Yair, Sade, Tal, Zedaka, Hadar, Gilboa, Merav, Yahel, Gitai, Chefetz, Benny“…All samples were filtered using 90mmGF/F filters (nominal pore size of 0.7 µm, MGF, Sartorius, Göttingen, Germany) and immediately frozen (−20°C) before chemical analysis. …”
Publicado 2023
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292por Ribbe, Katja, Friedrichs, Heidi, Begemann, Martin, Grube, Sabrina, Papiol, Sergi, Kästner, Anne, Gerchen, Martin F, Ackermann, Verena, Tarami, Asieh, Treitz, Annika, Flögel, Marlene, Adler, Lothar, Aldenhoff , Josef B, Becker-Emner, Marianne, Becker, Thomas, Czernik, Adelheid, Dose, Matthias, Folkerts, Here, Freese, Roland, Günther , Rolf, Herpertz, Sabine, Hesse, Dirk, Kruse, Gunther, Kunze, Heinrich, Franz, Michael, Löhrer, Frank, Maier, Wolfgang, Mielke, Andreas, Müller-Isberner, Rüdiger, Oestereich, Cornelia, Pajonk, Frank-Gerald, Pollmächer, Thomas, Schneider, Udo, Schwarz, Hans-Joachim, Kröner-Herwig, Birgit, Havemann-Reinecke, Ursula, Frahm, Jens, Stühmer, Walter, Falkai, Peter, Brose, Nils, Nave, Klaus-Armin, Ehrenreich, Hannelore“…Based on the assumption that valuable information about relevant genetic and environmental disease mechanisms can be obtained by association studies on patient cohorts of ≥ 1000 patients, if performed on detailed clinical datasets and quantifiable biological readouts, we generated a new schizophrenia data base, the GRAS (Göttingen Research Association for Schizophrenia) data collection. …”
Publicado 2010
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293por Staunstrup, Nicklas Heine, Madsen, Johannes, Primo, Maria Nascimento, Li, Juan, Liu, Ying, Kragh, Peter M., Li, Rong, Schmidt, Mette, Purup, Stig, Dagnæs-Hansen, Frederik, Svensson, Lars, Petersen, Thomas K., Callesen, Henrik, Bolund, Lars, Mikkelsen, Jacob Giehm“…In efforts to generate a porcine model of cutaneous inflammation, we employed the Sleeping Beauty DNA transposon system for production of transgenic cloned Göttingen minipigs expressing human β1 or α2 integrin under the control of a promoter specific for subrabasal keratinocytes. …”
Publicado 2012
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294por Lamkowski, Andreas, Forcheron, Fabien, Agay, Diane, Ahmed, Emad A., Drouet, Michel, Meineke, Viktor, Scherthan, Harry“…Here, we investigated γH2AX and DNA repair foci in peripheral blood lymphocytes of Göttingen minipigs that experienced acute partial body irradiation (PBI) with 49 Gy (±6%) Co-60 γ-rays of the upper lumbar region. …”
Publicado 2014
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295por Schwarz, Markus L., Schneider-Wald, Barbara, Brade, Joachim, Schleich, Dieter, Schütte, Andy, Reisig, Gregor“…Eighty samples were taken from knee joints of Göttingen Minipigs with this punching technique. The time needed for the harvesting of the samples was 7.52 min (±2.18 min), the parallelism of the sides of the cylinders deviated by −0.63° (CI: −1.33°; 0.08°) and the surface of the cartilage deviated from the perpendicularity by 4.86° (CI: 4.154°; 5.573°). …”
Publicado 2015
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296por Bøje, Sarah, Olsen, Anja Weinreich, Erneholm, Karin, Agerholm, Jørgen Steen, Jungersen, Gregers, Andersen, Peter, Follmann, Frank“…Ideally, this vaccine is required to induce a combined response of Th1 cell-mediated immune (CMI) response in concert with neutralizing antibodies. Using a novel Göttingen minipig animal model, we evaluated the immunogenicity and efficacy of a multi-subunit vaccine formulated in the strong Th1-inducing adjuvant CAF01. …”
Publicado 2016
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297por Lillethorup, Thea P., Glud, Andreas N., Alstrup, Aage K. O., Noer, Ove, Nielsen, Erik H. T., Schacht, Anna C., Landeck, Natalie, Kirik, Deniz, Orlowski, Dariusz, Sørensen, Jens Christian H., Doudet, Doris J., Landau, Anne M.“…We used positron emission tomography to investigate longitudinal effects of chronic intracerebroventricular exposure to the proteasome inhibitor lactacystin on monoaminergic projections and neuroinflammation. Göttingen minipigs were implanted in the cisterna magna with a catheter connected to a subcutaneous injection port. …”
Publicado 2018
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298por Koren, Gerbrand, Schneider, Linda, van der Velde, Ivar R., van Schaik, Erik, Gromov, Sergey S., Adnew, Getachew A., Mrozek Martino, Dorota J., Hofmann, Magdalena E. G., Liang, Mao‐Chang, Mahata, Sasadhar, Bergamaschi, Peter, van der Laan‐Luijkx, Ingrid T., Krol, Maarten C., Röckmann, Thomas, Peters, Wouter“…In addition, we compare our model results with tropospheric measurements of Δ(17)O in CO(2) from Göttingen (Germany) and Taipei (Taiwan), which shows some agreement but we also find substantial discrepancies that are subsequently discussed. …”
Publicado 2019
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299CARGEL Bioscaffold improves cartilage repair tissue after bone marrow stimulation in a minipig modelpor Hede, K., Christensen, B. B., Olesen, M. L., Thomsen, J. S., Foldager, C. B., Lind, M. C.“…PURPOSE: To gain knowledge of the repair tissue in critically sized cartilage defects using bone marrow stimulation combined with CARGEL Bioscaffold (CB) compared with bone marrow stimulation (BMS) alone in a validated animal model. METHODS: Six adult Göttingen minipigs received two chondral defects in each knee. …”
Publicado 2020
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300“…The conventional pig is a well-established model for PA and the neonatal Göttingen minipig should be further explored for PA under hypothermia conditions, as it is the most commonly used pig strain in nonclinical drug development. …”
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