Increase in lamin B1 promotes telomere instability by disrupting the shelterin complex in human cells

por Pennarun, Gaëlle, Picotto, Julien, Etourneaud, Laure, Redavid, Anna-Rita, Certain, Anaïs, Gauthier, Laurent R, Fontanilla-Ramirez, Paula, Busso, Didier, Chabance-Okumura, Caroline, Thézé, Benoît, Boussin, François D, Bertrand, Pascale
Publicado 2021

Pegylated interferon 2a and ruxolitinib induce a high rate of oral complications among patients with myeloproliferative neoplasms

por Orliaguet, Marie, Boisramé, Sylvie, Eveillard, Jean‐Richard, Pan‐Petesch, Brigitte, Couturier, Marie‐Anne, Rebière, Vincent, Guillerm, Gaelle, Le Bousse‐Kerdiles, Marie‐Caroline, Misery, Laurent, Lippert, Eric, Ianotto, Jean‐Christophe
Publicado 2020

Deletion of the Lmna gene in fibroblasts causes senescence-associated dilated cardiomyopathy by activating the double-stranded DNA damage response and induction of senescence-assoc...

por Rouhi, Leila, Auguste, Gaelle, Zhou, Qiong, Lombardi, Raffaella, Olcum, Melis, Pourebrahim, Kimia, Cheedipudi, Sirisha M., Asghar, Saman, Hong, Kui, Robertson, Matthew J., Coarfa, Cristian, Gurha, Priyatansh, Marian, Ali J.
Publicado 2022

Functionalized Nanogels with Endothelin-1 and Bradykinin Receptor Antagonist Peptides Decrease Inflammatory and Cartilage Degradation Markers of Osteoarthritis in a Horse Organoid...

por Cullier, Aurélie, Cassé, Frédéric, Manivong, Seng, Contentin, Romain, Legendre, Florence, Garcia Ac, Aracéli, Sirois, Pierre, Roullin, Gaëlle, Banquy, Xavier, Moldovan, Florina, Bertoni, Lélia, Audigié, Fabrice, Galéra, Philippe, Demoor, Magali
Publicado 2022

Structural and Functional Characterization of Orcokinin B-like Neuropeptides in the Cuttlefish (Sepia officinalis)

por Endress, Maxime, Zatylny-Gaudin, Céline, Leprince, Jérôme, Lefranc, Benjamin, Corre, Erwan, Le Corguillé, Gildas, Bernay, Benoît, Leduc, Alexandre, Rangama, Jimmy, Mouret, Liza, Lafont, Anne-Gaëlle, Bondon, Arnaud, Henry, Joël
Publicado 2022

Dupilumab Provides Significant Clinical Benefit in a Phase 3 Trial in Adolescents with Uncontrolled Atopic Dermatitis Irrespective of Prior Systemic Immunosuppressant Use

por DELEURAN, Mette, MARCOUX, Danielle, DE BRUIN-WELLER, Marjolein S., IRVINE, Alan D., BASELGA, Eulalia, AHN, Kangmo, CASTRO, Ana Paula, BANSAL, Ashish, CHAO, Jingdong, BÉGO-LE BAGOUSSE, Gaëlle, ROSSI, Ana B.
Publicado 2021

Dupilumab Provides Rapid and Sustained Clinically Meaningful Responses in Adults with Moderate-to-severe Atopic Dermatitis

por SILVERBERG, Jonathan I., SIMPSON, Eric L., BOGUNIEWICZ, Mark, DE BRUIN-WELLER, Marjolein S., FOLEY, Peter, KATAOKA, Yoko, BÉGO-LE BAGOUSSE, Gaëlle, CHEN, Zhen, SHUMEL, Brad, CHAO, Jingdong, ROSSI, Ana B.
Publicado 2021

Type I arginine methyltransferases are intervention points to unveil the oncogenic Epstein-Barr virus to the immune system

por Angrand, Gaelle, Quillévéré, Alicia, Loaëc, Nadège, Dinh, Van-Trang, Le Sénéchal, Ronan, Chennoufi, Rahima, Duchambon, Patricia, Keruzoré, Marc, Martins, Rodrigo Prado, Teulade-Fichou, Marie-Paule, Fåhraeus, Robin, Blondel, Marc
Publicado 2022

Overview of meningococcal epidemiology and national immunization programs in children and adolescents in 8 Western European countries

por Pinto Cardoso, Gaëlle, Lagrée-Chastan, Marion, Caseris, Marion, Gaudelus, Joël, Haas, Hervé, Leroy, Jean-Philippe, Bakhache, Pierre, Pujol, Jean-François, Werner, Andreas, Dommergues, Marie-Aliette, Pauquet, Emilie, Pinquier, Didier
Publicado 2022

Alternate-day dosing of pomalidomide in relapsed/ refractory multiple myeloma: a multicenter, single-arm phase 2 trial

por Zander, Thilo, Pabst, Thomas, Schär, Sämi, Aebi, Stefan, Mey, Ulrich, Novak, Urban, Lerch, Erika, Rhyner Agocs, Gaëlle, Goede, Jeroen, Maniecka, Zuzanna, Hayoz, Stefanie, Rüfer, Axel, Renner, Christoph, Driessen, Christoph
Publicado 2023

Risk of Bronchial Complications After Lung Transplantation With Respiratory Corynebacteria. Results From a Monocenter Retrospective Cohort Study

por Sandot, Adèle, Grall, Nathalie, Rodier, Thomas, Bunel, Vincent, Godet, Cendrine, Weisenburger, Gaëlle, Tran-Dinh, Alexy, Montravers, Philippe, Mordant, Pierre, Castier, Yves, Eloy, Philippine, Armand-Lefevre, Laurence, Mal, Hervé, Messika, Jonathan
Publicado 2023

Black Poplar (Populus nigra L.) Root Extracellular Trap, Structural and Molecular Remodeling in Response to Osmotic Stress

por Busont, Océane, Durambur, Gaëlle, Bernard, Sophie, Plasson, Carole, Joudiou, Camille, Baude, Laura, Chefdor, Françoise, Depierreux, Christiane, Héricourt, François, Larcher, Mélanie, Malik, Sonia, Boulogne, Isabelle, Driouich, Azeddine, Carpin, Sabine, Lamblin, Frédéric
Publicado 2023

Oncogenic CALR mutant C-terminus mediates dual binding to the thrombopoietin receptor triggering complex dimerization and activation

por Papadopoulos, Nicolas, Nédélec, Audrey, Derenne, Allison, Şulea, Teodor Asvadur, Pecquet, Christian, Chachoua, Ilyas, Vertenoeil, Gaëlle, Tilmant, Thomas, Petrescu, Andrei-Jose, Mazzucchelli, Gabriel, Iorga, Bogdan I., Vertommen, Didier, Constantinescu, Stefan N.
Publicado 2023

Kidney allograft rejection is associated with an imbalance of B cells, regulatory T cells and differentiated CD28-CD8+ T cells: analysis of a cohort of 1095 graft biopsies

por Mai, Hoa Le, Degauque, Nicolas, Lorent, Marine, Rimbert, Marie, Renaudin, Karine, Danger, Richard, Kerleau, Clarisse, Tilly, Gaelle, Vivet, Anaïs, Le Bot, Sabine, Delbos, Florent, Walencik, Alexandre, Giral, Magali, Brouard, Sophie
Publicado 2023

Long-Term Effectiveness of Dupilumab in Patients with Atopic Dermatitis: Results up to 3 Years from the RELIEVE-AD Study

por Kimball, Alexa B., Delevry, Dimittri, Yang, Min, Chuang, Chien-Chia, Wang, Zhixiao, Bégo-Le-Bagousse, Gaëlle, Martins, Bruno, Wu, Eric, Shumel, Brad, Wang, Jessie, Sierka, Debra, Chao, Jingdong, Strober, Bruce
Publicado 2023

Intact satellite cells lead to remarkable protection against Smn gene defect in differentiated skeletal muscle

por Nicole, Sophie, Desforges, Benedicte, Millet, Gaelle, Lesbordes, Jeanne, Cifuentes-Diaz, Carmen, Vertes, Dora, Cao, My Linh, De Backer, Fabienne, Languille, Laetitia, Roblot, Natacha, Joshi, Vandana, Gillis, Jean-Marie, Melki, Judith
Publicado 2003

Teriflunomide reduces relapse-related neurological sequelae, hospitalizations and steroid use

por O’Connor, Paul W., Lublin, Fred D., Wolinsky, Jerry S., Confavreux, Christian, Comi, Giancarlo, Freedman, Mark S., Olsson, Tomas P., Miller, Aaron E., Dive-Pouletty, Catherine, Bégo-Le-Bagousse, Gaëlle, Kappos, Ludwig
Publicado 2013

SETD2-Dependent Histone H3K36 Trimethylation Is Required for Homologous Recombination Repair and Genome Stability

por Pfister, Sophia X., Ahrabi, Sara, Zalmas, Lykourgos-Panagiotis, Sarkar, Sovan, Aymard, François, Bachrati, Csanád Z., Helleday, Thomas, Legube, Gaëlle, La Thangue, Nicholas B., Porter, Andrew C.G., Humphrey, Timothy C.
Publicado 2014

The association between Histone 3 Lysine 27 Trimethylation (H3K27me3) and prostate cancer: relationship with clinicopathological parameters

por Ngollo, Marjolaine, Lebert, Andre, Dagdemir, Aslihan, Judes, Gaelle, Karsli-Ceppioglu, Seher, Daures, Marine, Kemeny, Jean-Louis, Penault-Llorca, Frederique, Boiteux, Jean-Paul, Bignon, Yves-Jean, Guy, Laurent, Bernard-Gallon, Dominique
Publicado 2014

Comprehensive Mapping of Histone Modifications at DNA Double-Strand Breaks Deciphers Repair Pathway Chromatin Signatures

por Clouaire, Thomas, Rocher, Vincent, Lashgari, Anahita, Arnould, Coline, Aguirrebengoa, Marion, Biernacka, Anna, Skrzypczak, Magdalena, Aymard, François, Fongang, Bernard, Dojer, Norbert, Iacovoni, Jason S., Rowicka, Maga, Ginalski, Krzysztof, Côté, Jacques, Legube, Gaëlle
Publicado 2018