Efficacy of Cipargamin (KAE609) in a Randomized, Phase II Dose-Escalation Study in Adults in Sub-Saharan Africa With Uncomplicated Plasmodium falciparum Malaria

por Schmitt, Esther K, Ndayisaba, Gilles, Yeka, Adoke, Asante, Kwaku Poku, Grobusch, Martin P, Karita, Etienne, Mugerwa, Henry, Asiimwe, Stephen, Oduro, Abraham, Fofana, Bakary, Doumbia, Seydou, Su, Guoqin, Csermak Renner, Katalin, Venishetty, Vinay Kumar, Sayyed, Sarfaraz, Straimer, Judith, Demin, Ivan, Barsainya, Sarita, Boulton, Caroline, Gandhi, Preetam
Publicado 2021

WHO's Therapeutics and COVID-19 Living Guideline on mAbs needs to be reassessed

por Wu, Mary Y, Carr, Edward J, Harvey, Ruth, Mears, Harriet V, Kjaer, Svend, Townsley, Hermaleigh, Hobbs, Agnieszka, Ragno, Martina, Herman, Lou S, Adams, Lorin, Gamblin, Steve, Howell, Michael, Beale, Rupert, Brown, Michael, Williams, Bryan, Gandhi, Sonia, Swanton, Charles, Wall, Emma C, Bauer, David L V
Publicado 2023

Reduced-dose WBRT as consolidation treatment for patients with primary CNS lymphoma: an LOC network study

por Lesueur, Paul, Damaj, Gandhi, Hoang-Xuan, Khê, Roland, Virginie, Schmitt, Anna, Chinot, Olivier, Fabbro, Michel, Agapé, Philippe, Moluçon-Chabrot, Cécile, Chebrek, Safia, Alentorn, Agusti, Feuvret, Loic, Delgadillo, Daniel, Stefan, Dinu, Choquet, Sylvain, Nichelli, Lucia, Mokhtari, Karima, Mathon, Bertrand, Dureau, Sylvain, Soussain, Carole, Houillier, Caroline
Publicado 2022

Development and use of a high-throughput screen to identify novel modulators of the corticotropin releasing factor binding protein

por Haass-Koffler, Carolina L., Chase Francis, T., Gandhi, Pauravi, Patel, Reesha, Naemuddin, Mohammad, Nielsen, Carsten K., Bartlett, Selena E., Bonci, Antonello, Vasile, Stefan, Hood, Becky L., Suyama, Eigo, Hedrick, Michael P., Smith, Layton H., Limpert, Allison S., Roberto, Marisa, Cosford, Nicholas D.P., Sheffler, Douglas J.
Publicado 2022

Muscle weakness precedes atrophy during cancer cachexia and is linked to muscle-specific mitochondrial stress

por Delfinis, Luca J., Bellissimo, Catherine A., Gandhi, Shivam, DiBenedetto, Sara N., Garibotti, Madison C., Thuhan, Arshdeep K., Tsitkanou, Stavroula, Rosa-Caldwell, Megan E., Rahman, Fasih A., Cheng, Arthur J., Wiggs, Michael P., Schlattner, Uwe, Quadrilatero, Joe, Greene, Nicholas P., Perry, Christopher G.R.
Publicado 2022

Tumor loss-of-function mutations in STK11/LKB1 induce cachexia

por Iyengar, Puneeth, Gandhi, Aakash Y., Granados, Jorge, Guo, Tong, Gupta, Arun, Yu, Jinhai, Llano, Ernesto M., Zhang, Faya, Gao, Ang, Kandathil, Asha, Williams, Dorothy, Gao, Boning, Girard, Luc, Malladi, Venkat S., Shelton, John M., Evers, Bret M., Hannan, Raquibul, Ahn, Chul, Minna, John D., Infante, Rodney E.
Publicado 2023

BSBM-07 HIGH-DIMENSIONAL HISTOPATHOLOGIC EVALUATION OF THE HYPOXIC MICROENVIRONMENT IN GLIOBLASTOMA

por Mansouri, Sheila, Zaidi, Mark, Singh, Olivia, Karimi, Shirin, Lombard, Phoebe, Dvorkin-Gheva, Anna, Velasquez, Carlos, Ali, Hafsah, Devaraja, Kaviya, Sosa, Julio, Patil, Vikas, Wei, QingXia, Wu, Ronald, Li, Mira, Cheung, May, Voisin, Mathew, Gao, Andrew, Hedley, David, Aldape, Kenneth, Wouters, Bradley, Zadeh, Gelareh, Gandhi, Shreya
Publicado 2023

Activation of GPR44 decreases severity of myeloid leukemia via specific targeting of leukemia initiating stem cells

por Qian, Fenghua, Nettleford, Shaneice K., Zhou, Jiayan, Arner, Brooke E., Hall, Molly A., Sharma, Arati, Annageldiyev, Charyguly, Rossi, Randy M., Tukaramrao, Diwakar B., Sarkar, Deborpita, Hegde, Shailaja, Gandhi, Ujjawal H., Finch, Emily R., Goodfield, Laura, Quickel, Michael D., Claxton, David F., Paulson, Robert F., Prabhu, K. Sandeep
Publicado 2023

A viral CTL escape mutation leading to immunoglobulin-like transcript 4–mediated functional inhibition of myelomonocytic cells

por Lichterfeld, Mathias, Kavanagh, Daniel G., Williams, Katie L., Moza, Beenu, Mui, Stanley K., Miura, ToshiYuki, Sivamurthy, Rohini, Allgaier, Rachel, Pereyra, Florencia, Trocha, Alicja, Feeney, Margaret, Gandhi, Rajesh T., Rosenberg, Eric S., Altfeld, Marcus, Allen, Todd M., Allen, Rachel, Walker, Bruce D., Sundberg, Eric J., Yu, Xu G.
Publicado 2007

Extracellular RNAs: development as biomarkers of human disease

por Quinn, Joseph F., Patel, Tushar, Wong, David, Das, Saumya, Freedman, Jane E., Laurent, Louise C., Carter, Bob S., Hochberg, Fred, Keuren-Jensen, Kendall Van, Huentelman, Matt, Spetzler, Robert, Kalani, M. Yashar S., Arango, Jorge, Adelson, P. David, Weiner, Howard L., Gandhi, Roopali, Goilav, Beatrice, Putterman, Chaim, Saugstad, Julie A.
Publicado 2015

Alpha synuclein aggregation drives ferroptosis: an interplay of iron, calcium and lipid peroxidation

por Angelova, Plamena R., Choi, Minee L., Berezhnov, Alexey V., Horrocks, Mathew H., Hughes, Craig D., De, Suman, Rodrigues, Margarida, Yapom, Ratsuda, Little, Daniel, Dolt, Karamjit S., Kunath, Tilo, Devine, Michael J., Gissen, Paul, Shchepinov, Mikhail S., Sylantyev, Sergiy, Pavlov, Evgeny V., Klenerman, David, Abramov, Andrey Y., Gandhi, Sonia
Publicado 2020

Patient reported changes in metabolic health during lockdown: A cross sectional digital connect survey in people with type 2 diabetes

por Kovil, Rajiv, Shah, Tejas, Chawla, Manoj, Karkhanis, Shefali, Padhye, Dakshata, Sanghvi, Ami, Kale, Mayura Choudhari, Chawla, Purvi, Prabhu, Nikhil, Dhandhania, Vinay, Shah, Kiran, Sachdev, Manish, Methil, Vinod, Tanna, Snehal, Nayak, Kamlesh, Bagri, Seema, Patil, Pratiksha, Gandhi, Alka, Aversekar, Sheetal, Maheshwari, Ragini, Kothari, Akshay, Dhope, Rahul, Mehta, Anushree
Publicado 2020

Prothrombotic autoantibodies in serum from patients hospitalized with COVID-19

por Zuo, Yu, Estes, Shanea K., Ali, Ramadan A., Gandhi, Alex A., Yalavarthi, Srilakshmi, Shi, Hui, Sule, Gautam, Gockman, Kelsey, Madison, Jacqueline A., Zuo, Melanie, Yadav, Vinita, Wang, Jintao, Woodard, Wrenn, Lezak, Sean P., Lugogo, Njira L., Smith, Stephanie A., Morrissey, James H., Kanthi, Yogendra, Knight, Jason S.
Publicado 2020

Long-Term Evaluation of Women Referred to a Breast Cancer Family History Clinic (Manchester UK 1987–2020)

por Howell, Anthony, Gandhi, Ashu, Howell, Sacha, Wilson, Mary, Maxwell, Anthony, Astley, Susan, Harvie, Michelle, Pegington, Mary, Barr, Lester, Baildam, Andrew, Harkness, Elaine, Hopwood, Penelope, Wisely, Julie, Wilding, Andrea, Greenhalgh, Rosemary, Affen, Jenny, Maurice, Andrew, Cole, Sally, Wiseman, Julia, Lalloo, Fiona, French, David P., Evans, D. Gareth
Publicado 2020

1506. Burden of Respiratory Syncytial Virus (RSV) and Other Lower Respiratory Tract Viral Infections During the First Two Years of Life: a Prospective Study

por Madhi, Shabir A, Ceballos, Ana, Colas, Jo Ann, Cousin, Luis, D’Andrea, Ulises, Dieussaert, Ilse, Domachowske, Joseph B, Englund, Janet A, Gandhi, Sanjay, Haars, Gerco, Hercor, Mélanie, de Heusch, Magali, Jose, Lisa, Langley, Joanne M, Leach, Amanda, Silas, Peter, Teeratakulpisarn, Jamaree, Vesikari, Timo, Stoszek, Sonia K
Publicado 2020

Nonclassical Monocytes Are Prone to Migrate Into Tumor in Diffuse Large B-Cell Lymphoma

por Le Gallou, Simon, Lhomme, Faustine, Irish, Jonathan M., Mingam, Anna, Pangault, Celine, Monvoisin, Celine, Ferrant, Juliette, Azzaoui, Imane, Rossille, Delphine, Bouabdallah, Krimo, Damaj, Gandhi, Cartron, Guillaume, Godmer, Pascal, Le Gouill, Steven, Casasnovas, René-Olivier, Molina, Thierry Jo, Houot, Roch, Lamy, Thierry, Tarte, Karin, Fest, Thierry, Roussel, Mikael
Publicado 2021

Androgen receptor signaling promotes Treg suppressive function during allergic airway inflammation

por Gandhi, Vivek D., Cephus, Jacqueline-Yvonne, Norlander, Allison E., Chowdhury, Nowrin U., Zhang, Jian, Ceneviva, Zachary J., Tannous, Elie, Polosukhin, Vasiliy V., Putz, Nathan D., Wickersham, Nancy, Singh, Amrit, Ware, Lorraine B., Bastarache, Julie A., Shaver, Ciara M., Chu, Hong Wei, Peebles, R. Stokes, Newcomb, Dawn C.
Publicado 2022

Multimodal Investigation of Neuroinflammation in Aviremic Patients With HIV on Antiretroviral Therapy and HIV Elite Controllers

por Sari, Hasan, Galbusera, Riccardo, Bonnier, Guillaume, Lin, Yang, Alshelh, Zeynab, Torrado-Carvajal, Angel, Mukerji, Shibani S., Ratai, Eva M., Gandhi, Rajesh T., Chu, Jacqueline T., Akeju, Oluwaseun, Orhurhu, Vwaire, Salvatore, Andrew N., Sherman, Janet, Kwon, Douglas S., Walker, Bruce, Rosen, Bruce, Price, Julie C., Pollak, Lauren E., Loggia, Marco, Granziera, Cristina
Publicado 2022

UACA locus is associated with breast cancer chemoresistance and survival

por Zhu, Qianqian, Schultz, Emily, Long, Jirong, Roh, Janise M., Valice, Emily, Laurent, Cecile A., Radimer, Kelly H., Yan, Li, Ergas, Isaac J., Davis, Warren, Ranatunga, Dilrini, Gandhi, Shipra, Kwan, Marilyn L., Bao, Ping-Ping, Zheng, Wei, Shu, Xiao-Ou, Ambrosone, Christine, Yao, Song, Kushi, Lawrence H.
Publicado 2022

Optimizing infant HIV diagnosis with additional screening at immunization clinics in three sub‐Saharan African settings: a cost‐effectiveness analysis

por Dunning, Lorna, Gandhi, Aditya R, Penazzato, Martina, Soeteman, Djøra I, Revill, Paul, Frank, Simone, Phillips, Andrew, Dugdale, Caitlin, Abrams, Elaine, Weinstein, Milton C, Newell, Marie‐Louise, Collins, Intira J, Doherty, Meg, Vojnov, Lara, Fassinou Ekouévi, Patricia, Myer, Landon, Mushavi, Angela, Freedberg, Kenneth A, Ciaranello, Andrea L
Publicado 2021