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441Publicado 1994“…We have used video-enhanced DIC microscopy to examine the effects of XMAP, a Mr 215,000 microtubule-associated protein from Xenopus eggs (Gard, D.L., and M. W. Kirschner. 1987. J. Cell Biol. 105:2203-2215), on the dynamic instability of microtubules nucleated from axoneme fragments in vitro. …”
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442por Tielemans, Eric, Prullage, Joe, Tomoko, Otsuki, Liebenberg, Julian, Capári, Balázs, Sotiraki, Smaragda, Kostopoulou, Despoina, Ligda, Panagiota, Ulrich, Michael, Knaus, Martin“…Esafoxolaner, a purified enantiomer of afoxolaner with insecticidal and acaricidal properties, is combined with eprinomectin and praziquantel, nematodicidal and cestodicidal compounds, in NexGard(®) Combo, a novel topical endectoparasiticide formulation for cats. …”
Publicado 2021
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443“…IN vaccination using VLP with MB was compared to IN delivery VLP with cholera toxin (CT) or gardiquimod (GARD) and to parenteral VLP delivery with alum; the MB groups were equivalent to CT and GARD and superior to alum in inducing mucosal immune responses and stimulated equivalent systemic VLP-specific antibodies. …”
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444por Jacquot, Virginie, Buellet, Prescillia, Letendre, Laura, Tong, Wei, Li, Henry, Tielemans, Eric“…Esafoxolaner, a purified enantiomer of afoxolaner with insecticidal and acaricidal properties, is combined with eprinomectin and praziquantel in NexGard(®) Combo, a novel topical endectoparasiticide formulation for cats. …”
Publicado 2021
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445por Gupta, Aradhana, Baker, Christine, Wang, Hailun, Targa, Norba, Pfefferkorn, Anthony, Tielemans, Eric“…The safety profile of NexGard(®) Combo, a novel topical product for cats combining esafoxolaner, eprinomectin and praziquantel, for the treatment and prevention of internal and external parasites, was evaluated in kittens, in two margin-of-safety studies (Studies #1 and #2), and in an oral tolerance study (Study #3). …”
Publicado 2021
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446“…Efficacy against fleas was ≥ 97.9% in the Simparica Trio™ group and ≥ 96.1% in the NexGard® Spectra group. Efficacy against ticks was ≥ 94.8% in the Simparica Trio™ group and ≥ 94.4% in the NexGard® Spectra group. …”
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447por Negussie, Ayele H., Mikhail, Andrew S., Owen, Joshua W., Hong, Natalie, Carlson, Camella J., Tang, Yiqing, Carrow, Kendal Paige, Mauda-Havakuk, Michal, Lewis, Andrew L., Karanian, John W., Pritchard, William F., Wood, Bradford J.“…Maximum drug loading was 204.54 ± 3.87, 65.97 ± 1.54, 65.95 ± 6.96, 65.28 ± 3.09, and 148.05 ± 2.24 mg of drug per milliliter of DC Bead LUMI for Dox, GARD, DSR 6434, IMQ, and BMS-202, respectively. Fast loading and subsequent rapid release in saline were observed for IMQ, GARD, and DSR 6434. …”
Publicado 2022
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448por Wildemeersch, Dirk, Pett, Ansgar, Jandi, Sohela, Hasskamp, Thomas, Rowe, Patrick, Vrijens, Marc“…RESULTS: The mean transverse diameter in nulliparous and parous women is significantly less than the length of the transverse arm of the TCu380A IUD (ParaGard, Duramed, NY, USA) or the levonorgestrel intrauterine system (Mirena, Bayer, Germany). …”
Publicado 2013
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449por Beugnet, Frédéric, de Vos, Christa, Liebenberg, Julian, Halos, Lénaïg, Larsen, Diane, Fourie, Josephus“…The acaricidal efficacy of afoxolaner (NexGard(®), Merial) was evaluated against Sarcoptes scabiei var. canis in a field efficacy study, when administered orally at a minimum dose of 2.5 mg/kg to dogs naturally infested with the mites. …”
Publicado 2016
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450por Perier, Nadège, Lebon, Wilfried, Meyer, Leon, Lekouch, Noua, Aouiche, Nesrine, Beugnet, Frédéric“…Six dogs were randomly allocated based on body weight to an untreated control group and six to an afoxolaner (NexGard(®)) treated group. In the treatment group, afoxolaner was administered orally on Day 0 in accordance with label instructions. …”
Publicado 2019
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451“…Furthermore, L. acidophilus formed statistically significantly more biofilm on OrthoDots®CLEAR (OrVance) than Brace Gard®(Infa-Lab Inc.) at the 72nd, 96th and 120th hours (p < 0.05). …”
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452por Baker, Christine, McCall, John, Mansour, Abdelmoneim, McCall, Scott, Shaffer, Tayna, Wakeland, Kenneth, Mitchell, Elizabeth, Frost, Justin, Tielemans, Eric, Bowman, Dwight“…NexGard(®) Combo is a novel topical endectoparasiticide formulation for cats combining the insecticide/acaricide esafoxolaner, the nematodicide eprinomectin and the cestodicide praziquantel. …”
Publicado 2021
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453“…Two groups of 7 cats were formed: an untreated control group, and a NexGard(®) Combo group treated once on Day 0 at the label dose. …”
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454por dos Santos, Katharine Costa, Tielemans, Eric, Cutolo, Andre Antonio, Guedes, Paula Elisa Brandão, Harvey, Tatiani Vitor, de Carvalho Teixeira, Jamille Bispo, Vitor, Rebeca Costa, da Paixão Sevá, Anaiá, de Melo Navarro, Adan William, Lima, Ana Carolina Ribeiro, Botteon, Karin Denise, Bittar, Thammy Vieira, Albuquerque, George Rêgo, de Almeida Borges, Fernando, Beugnet, Frederic, Carlos, Renata Santiago Alberto“…CONCLUSIONS: NexGard Spectra(®) was demonstrated to be highly effective against canine tungiasis. …”
Publicado 2023
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455por Shen, Feichen, Liu, Sijia, Wang, Yanshan, Wen, Andrew, Wang, Liwei, Liu, Hongfang“…Macro-average F-measure for string, SNOMED, and GARD match were 0.32, 0.42, and 0.63, respectively. …”
Publicado 2018
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456por Albrekt, Ann-Sofie, Johansson, Henrik, Börje, Anna, Borrebaeck, Carl, Lindstedt, Malin“…METHODS: Recently, we presented the Genomic Allergen Rapid Detection (GARD) assay for assessment of chemical sensitizers. …”
Publicado 2014
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457por Chuchalin, Alexander G, Khaltaev, Nikolai, Antonov, Nikolay S, Galkin, Dmitry V, Manakov, Leonid G, Antonini, Paola, Murphy, Michael, Solodovnikov, Alexander G, Bousquet, Jean, Pereira, Marcelo HS, Demko, Irina V“…The Global Alliance against Chronic Respiratory Diseases (GARD) was formed following a mandate from the World Health Assembly to address this serious and growing health problem. …”
Publicado 2014
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458por Horikoshi, Renato J., Bernardi, Daniel, Bernardi, Oderlei, Malaquias, José B., Okuma, Daniela M., Miraldo, Leonardo L., Amaral, Fernando S. de A. e, Omoto, Celso“…However, the heterozygous from HX-R × Sus, VT-R × Sus, PW-R × Sus and Vip-R × Sus had complete mortality on YieldGard VT PRO, PowerCore, Agrisure Viptera, and Agrisure Viptera 3, whereas the HX-R × Sus and Vip-R × Sus strains survived on Herculex maize. …”
Publicado 2016
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459por Carithers, Doug, Crawford, Jordan, de Vos, Christa, Lotriet, Alta, Fourie, Josephus“…BACKGROUND: The efficacy of a single 2.5 mg/kg dose of afoxolaner (NexGard®, Merial) against induced Otodectes cynotis infestations was assessed in eight afoxolaner-treated dogs, compared to eight untreated dogs. …”
Publicado 2016
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460por La Paz, Jose Luis, Pla, Maria, Centeno, Emilio, Vicient, Carlos M., Puigdomènech, Pere“…The insect resistant maize YieldGard MON810 was studied to assess the extent to which introduction of a transgene may putatively alter the expression of endogenous genes by comparison of various GM lines vs. their non-transgenic counterparts. …”
Publicado 2014
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