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141por Ngu, Lisa, Ray, Debarpita, Watson, Samantha S., Beuning, Penny J., Ondrechen, Mary Jo, O’Doherty, George A.“…A diastereoselective synthesis of the β-anomer of glycinamide ribonucleotide (β-GAR) has been developed. The synthesis was accomplished in nine steps from D-ribose and occurred in 5% overall yield. …”
Publicado 2022
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142“… We report here the production of transgenic potato plants expressing the major capsid protein VP6 of bovine group A rotavirus (GAR). Transgenic plants under the control of a cauliflower mosaic virus 35S promoter, or a modified promoter linked to the tobacco mosaic virus 5′-untranslated sequence were positive for GAR antigens by ELISA. …”
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143por Sleigh, James N., Mech, Aleksandra M., Aktar, Tahmina, Zhang, Yuxin, Schiavo, Giampietro“…Dominant, missense mutations in the widely and constitutively expressed GARS1 gene cause peripheral neuropathy that usually begins in adolescence and principally impacts the upper limbs. …”
Publicado 2020
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144por Lee, Steven P., Brooks, Jill M., Al-Jarrah, Hatim, Thomas, Wendy A., Haigh, Tracey A., Taylor, Graham S., Humme, Sibille, Schepers, Aloys, Hammerschmidt, Wolfgang, Yates, John L., Rickinson, Alan B., Blake, Neil W.“…Endogenously expressed EBNA1 is therefore accessible to the MHC class I pathway despite GAr-mediated stabilization of the mature protein. …”
Publicado 2004
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145por Gaonkar, Raghuvir H., Ganguly, Soumya, Dewanjee, Saikat, Sinha, Samarendu, Gupta, Amit, Ganguly, Shantanu, Chattopadhyay, Dipankar, Chatterjee Debnath, Mita“…Garcinol (GAR) is a naturally occurring polyisoprenylated phenolic compound. …”
Publicado 2017
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146“…Additionally, active site superposition with E.coli PurT (EcPurT) showed that residues involved in the ATP-binding site in MtbPurT exhibited structural similarity but had notable difference in the GAR-binding site. The loop 383-389 in MtbPurT was much shorter and shifted 5.7 Å away from the phosphate of the GAR substrate. …”
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147por Lambert, Justin, Ghadry-Tavi, Rouzbeh, Knuff, Kate, Jutras, Marc, Siever, Jodi, Mick, Paul, Roque, Carolyn, Jones, Gareth, Little, Jonathan, Miller, Harry, Van Bergen, Colin, Kurtz, Donna, Murphy, Mary Ann, Jones, Charlotte Ann“…Intervention sessions will include 45 min of strengthening, balance and resistance exercises, 30 min of group walking at a self-selected pace and 60 min of interactive health education or GAR. The control group will attend 60-min GAR sessions. …”
Publicado 2017
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148por Darzacq, Xavier, Kittur, Nupur, Roy, Sujayita, Shav-Tal, Yaron, Singer, Robert H., Meier, U. Thomas“…NAF1 and all of the core proteins except GAR1 are recruited to the site of transcription. …”
Publicado 2006
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149“…The main results reveal that on a behavioral level, a low GAR leads to shorter interaction durations and that human participants change their GAR to mimic the robot. …”
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150por Metzelthin, Silke F, Daniëls, Ramon, van Rossum, Erik, de Witte, Luc, van den Heuvel, Wim JA, Kempen, Gertrudis IJM“…Scores on the three instruments correlated significantly with each other (GFI - TFI, r = 0.87; GFI - SPQ, r = 0.47; TFI - SPQ, r = 0.42) and with the GARS (GFI - GARS, r = 0.57; TFI - GARS, r = 0.61; SPQ - GARS, r = 0.46). …”
Publicado 2010
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151por Farooq, Muhammad, Mansoor, Shahid, Guo, Hui, Amin, Imran, Chee, Peng W., Azim, M. Kamran, Paterson, Andrew H.“…The highest gene copy number was observed for gar-miR7504 followed by gar-miR166, gar-miR8771, gar-miR156, and gar-miR7484. …”
Publicado 2017
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152“…Mannose phosphotransferase system (Man-PTS) serves as a receptor for several bacteriocins in sensitive bacterial cells, namely subclass IIa bacteriocins (pediocin-like; pediocins) and subclass IId ones - lactococcin A (LcnA), lactococcin B (LcnB) and garvicin Q (GarQ). Here, to identify the receptor for three other narrow-spectrum subclass IId bacteriocins - garvicins A, B and C (GarA-C) Lactococcus garvieae mutants resistant to bacteriocins were generated and sequenced to look for mutations responsible for resistance. …”
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153“…We thus suggest a genomic estimated breeding value-assisted reduction method of the single nucleotide polymorphism (SNP) set (GARS) to address these difficulties. GARS is a BLUP-based SNP set decision presentation. …”
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154“…It is known that GARS mutants induce GARS axonopathies, including CMT type 2D (CMT2D) and distal spinal muscular atrophy type V (dSMA-V). …”
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155por Rouet, Romain, Henry, Jake Y., Johansen, Matt D., Sobti, Meghna, Balachandran, Harikrishnan, Langley, David B., Walker, Gregory J., Lenthall, Helen, Jackson, Jennifer, Ubiparipovic, Stephanie, Mazigi, Ohan, Schofield, Peter, Burnett, Deborah L., Brown, Simon H. J., Martinello, Marianne, Hudson, Bernard, Gilroy, Nicole, Post, Jeffrey J., Kelleher, Anthony, Jäck, Hans-Martin, Goodnow, Christopher C., Turville, Stuart G., Rawlinson, William D., Bull, Rowena A., Stewart, Alastair G., Hansbro, Philip M., Christ, Daniel“…This is exemplified by two human antibodies, GAR05, binding to epitope class 1, and GAR12, binding to a new epitope class 6 (located between class 3 and 5). …”
Publicado 2023
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156“…Here, we dissect the mechanism of function of CMT mutant glycyl-tRNA synthetase (CMT-GARS), using high-resolution ribosome profiling and reporter assays. …”
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157por Jennings, Matthew J, Kagiava, Alexia, Vendredy, Leen, Spaulding, Emily L, Stavrou, Marina, Hathazi, Denisa, Grüneboom, Anika, De Winter, Vicky, Gess, Burkhard, Schara, Ulrike, Pogoryelova, Oksana, Lochmüller, Hanns, Borchers, Christoph H, Roos, Andreas, Burgess, Robert W, Timmerman, Vincent, Kleopa, Kleopas A, Horvath, Rita“…We collected serum from mouse models of CMT1A (C61 het), CMT2D (Gars(C201R), Gars(P278KY)), CMT1X (Gjb1-null), CMT2L (Hspb8(K141N)) and from CMT patients with genotypes including CMT1A (PMP22d), CMT2D (GARS), CMT2N (AARS) and other rare genetic forms of CMT. …”
Publicado 2022
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158“…Both SGE and GAR significantly reduced the high serum total cholesterol (TC), triglyceride (TG) and low-density lipoprotein levels induced by HFD. …”
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159“…However, since not all of the BacSJ-resistant mutants exhibited cross-resistance to GarQ, we propose that BacSJ interacts with Man-PTS in a manner slightly different from that of GarQ.…”
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160por Carral, Luis, Cartelle Barros, Juan José, Carro Fidalgo, Humberto, Camba Fabal, Carolina, Munín Doce, Alicia“…The focus is on the processes involved in creating green artificial reefs (GARs): manufacture, transport and installation. The starting point is the supply chain for the green artificial reef (GAR) units; greenhouse gas emissions (GHG) and energy needs for each phase are analysed. …”
Publicado 2021
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