Mild hyperlipidemia in mice aggravates platelet responsiveness in thrombus formation and exploration of platelet proteome and lipidome

por van Geffen, Johanna P., Swieringa, Frauke, van Kuijk, Kim, Tullemans, Bibian M. E., Solari, Fiorella A., Peng, Bing, Clemetson, Kenneth J., Farndale, Richard W., Dubois, Ludwig J., Sickmann, Albert, Zahedi, René P., Ahrends, Robert, Biessen, Erik A. L., Sluimer, Judith C., Heemskerk, Johan W. M., Kuijpers, Marijke J. E.
Publicado 2020

The CLL International Prognostic Index predicts outcomes in monoclonal B-cell lymphocytosis and Rai 0 CLL

por Parikh, Sameer A., Rabe, Kari G., Kay, Neil E., Call, Timothy G., Ding, Wei, Leis, Jose F., Kenderian, Saad S., Muchtar, Eli, Wang, Yucai, Koehler, Amber B., Schwager, Susan M., Lesnick, Connie E., Kleinstern, Geffen, Van Dyke, Daniel, Hanson, Curtis A., Braggio, Esteban, Slager, Susan L., Shanafelt, Tait D.
Publicado 2021

Platelet-primed interactions of coagulation and anticoagulation pathways in flow-dependent thrombus formation

por Brouns, Sanne L. N., van Geffen, Johanna P., Campello, Elena, Swieringa, Frauke, Spiezia, Luca, van Oerle, René, Provenzale, Isabella, Verdoold, Remco, Farndale, Richard W., Clemetson, Kenneth J., Spronk, Henri M. H., van der Meijden, Paola E. J., Cavill, Rachel, Kuijpers, Marijke J. E., Castoldi, Elisabetta, Simioni, Paolo, Heemskerk, Johan W. M.
Publicado 2020

Clinical outcomes in patients with node-negative breast cancer treated based on the recurrence score results: evidence from a large prospectively designed registry

por Stemmer, Salomon M., Steiner, Mariana, Rizel, Shulamith, Soussan-Gutman, Lior, Ben-Baruch, Noa, Bareket-Samish, Avital, Geffen, David B., Nisenbaum, Bella, Isaacs, Kevin, Fried, Georgeta, Rosengarten, Ora, Uziely, Beatrice, Svedman, Christer, McCullough, Debbie, Maddala, Tara, Klang, Shmuel H., Zidan, Jamal, Ryvo, Larisa, Kaufman, Bella, Evron, Ella, Karminsky, Natalya, Goldberg, Hadassah, Shak, Steven, Liebermann, Nicky
Publicado 2017

High-throughput elucidation of thrombus formation reveals sources of platelet function variability

por van Geffen, Johanna P., Brouns, Sanne L.N., Batista, Joana, McKinney, Harriet, Kempster, Carly, Nagy, Magdolna, Sivapalaratnam, Suthesh, Baaten, Constance C.F.M.J., Bourry, Nikki, Frontini, Mattia, Jurk, Kerstin, Krause, Manuela, Pillitteri, Daniele, Swieringa, Frauke, Verdoold, Remco, Cavill, Rachel, Kuijpers, Marijke J. E., Ouwehand, Willem H., Downes, Kate, Heemskerk, Johan W.M.
Publicado 2019

Comparative Analysis of Microfluidics Thrombus Formation in Multiple Genetically Modified Mice: Link to Thrombosis and Hemostasis

por Nagy, Magdolna, van Geffen, Johanna P., Stegner, David, Adams, David J., Braun, Attila, de Witt, Susanne M., Elvers, Margitta, Geer, Mitchell J., Kuijpers, Marijke J. E., Kunzelmann, Karl, Mori, Jun, Oury, Cécile, Pircher, Joachim, Pleines, Irina, Poole, Alastair W., Senis, Yotis A., Verdoold, Remco, Weber, Christian, Nieswandt, Bernhard, Heemskerk, Johan W. M., Baaten, Constance C. F. M. J.
Publicado 2019

Differential prognosis of single and multiple TP53 abnormalities in high-count MBL and untreated CLL

por Griffin, Rosalie, Wiedmeier-Nutor, Julia E., Parikh, Sameer A., McCabe, Chantal E., O'Brien, Daniel R., Boddicker, Nicholas J., Kleinstern, Geffen, Rabe, Kari G., Bruins, Laura, Brown, Sochilt, Bonolo de Campos, Cecilia, Ding, Wei, Leis, Jose F., Hampel, Paul J., Call, Timothy G., Van Dyke, Daniel L., Kay, Neil E., Cerhan, James R., Yan, Huihuang, Slager, Susan L., Braggio, Esteban
Publicado 2023

Polygenic risk score and risk of monoclonal B-cell lymphocytosis in caucasians and risk of chronic lymphocytic leukemia (CLL) in African Americans

por Kleinstern, Geffen, Weinberg, J. Brice, Parikh, Sameer A., Braggio, Esteban, Achenbach, Sara J., Robinson, Dennis P., Norman, Aaron D., Rabe, Kari G., Boddicker, Nicholas J., Vachon, Celine M., Lesnick, Connie E., Call, Timothy G., Brander, Danielle M., Rassenti, Laura Z., Kipps, Thomas J., Olson, Janet E., Cerhan, James R., Kay, Neil E., Furman, Richard R., Hanson, Curtis A., Shanafelt, Tait D., Slager, Susan L.
Publicado 2021

Genome Sequencing Highlights the Dynamic Early History of Dogs

por Freedman, Adam H., Gronau, Ilan, Schweizer, Rena M., Ortega-Del Vecchyo, Diego, Han, Eunjung, Silva, Pedro M., Galaverni, Marco, Fan, Zhenxin, Marx, Peter, Lorente-Galdos, Belen, Beale, Holly, Ramirez, Oscar, Hormozdiari, Farhad, Alkan, Can, Vilà, Carles, Squire, Kevin, Geffen, Eli, Kusak, Josip, Boyko, Adam R., Parker, Heidi G., Lee, Clarence, Tadigotla, Vasisht, Siepel, Adam, Bustamante, Carlos D., Harkins, Timothy T., Nelson, Stanley F., Ostrander, Elaine A., Marques-Bonet, Tomas, Wayne, Robert K., Novembre, John
Publicado 2014

Demographically-Based Evaluation of Genomic Regions under Selection in Domestic Dogs

por Freedman, Adam H., Schweizer, Rena M., Ortega-Del Vecchyo, Diego, Han, Eunjung, Davis, Brian W., Gronau, Ilan, Silva, Pedro M., Galaverni, Marco, Fan, Zhenxin, Marx, Peter, Lorente-Galdos, Belen, Ramirez, Oscar, Hormozdiari, Farhad, Alkan, Can, Vilà, Carles, Squire, Kevin, Geffen, Eli, Kusak, Josip, Boyko, Adam R., Parker, Heidi G., Lee, Clarence, Tadigotla, Vasisht, Siepel, Adam, Bustamante, Carlos D., Harkins, Timothy T., Nelson, Stanley F., Marques-Bonet, Tomas, Ostrander, Elaine A., Wayne, Robert K., Novembre, John
Publicado 2016

Evaluation of the Khorana, PROTECHT, and 5‐SNP scores for prediction of venous thromboembolism in patients with cancer

por Guman, Noori A. M., van Geffen, Roos J., Mulder, Frits I., van Haaps, Thijs F., Hovsepjan, Vahram, Labots, Mariette, Cirkel, Geert A., Y. F. L. de Vos, Filip, ten Tije, Albert J., Beerepoot, Laurens V., Tjan‐Heijnen, Vivianne C. G., van Laarhoven, Hanneke W. M., Hamberg, Paul, Vulink, Annelie J. E., Los, Maartje, Zwinderman, Aeilko H., Ferwerda, Bart, Lolkema, Martijn P. J. K., Steeghs, Neeltje, Büller, Harry R., Kamphuisen, Pieter W., van Es, Nick
Publicado 2021

Randomised controlled trial of first-line tyrosine-kinase inhibitor (TKI) versus intercalated TKI with chemotherapy for EGFR-mutated nonsmall cell lung cancer

por Gijtenbeek, Rolof G.P., van der Noort, Vincent, Aerts, Joachim G.J.V., Staal-van den Brekel, Jeske A., Smit, Egbert F., Krouwels, Frans H., Wilschut, Frank A., Hiltermann, T. Jeroen N., Timens, Wim, Schuuring, Ed, Janssen, Joost D.J., Goosens, Martijn, van den Berg, Paul M., de Langen, A. Joop, Stigt, Jos A., van den Borne, Ben E.E.M., Groen, Harry J.M., van Geffen, Wouter H., van der Wekken, Anthonie J.
Publicado 2022

Enhanced PeriOperative Care and Health protection programme for the prevention of surgical site infections after elective abdominal surgery (EPOCH): study protocol of a randomised...

por de Jonge, Stijn W, Wolfhagen, Niels, Boldingh, Quirine JJ, Bom, Wouter J, Posthuma, Linda M, Scheijmans, Jochem CG, van der Leeuw, Bart MF, van der Hoeven, Joost AB, Hering, Jens Peter, Sonneveld, Dirk JA, van Geffen, Otto E, Hendriks, Eduard R, Kluyver, Ewoud B, Demirkiran, Ahmet, van Lonkhuijzen, Luc RCW, Slotema, Thomas, Draaisma, Werner A, Koopman, Seppe JSHA, van Rossem, Charles C, Over, Linda M, van Duijvendijk, Peter, Dijkgraaf, Marcel GW, Hollmann, Markus W, Boermeester, Marja A
Publicado 2020

Timely administration of tocilizumab improves outcome of hospitalized COVID-19 patients

por Rutgers, Abraham, Westerweel, Peter E., van der Holt, Bronno, Postma, Simone, van Vonderen, Marit G. A., Piersma, Djura P., Postma, Douwe, van den Berge, Maarten, Jong, Eefje, de Vries, Marten, van der Burg, Leonie, Huugen, Dennis, van der Poel, Marjolein, Kampschreur, Linda M., Nijland, Marcel, Strijbos, Jaap H., Tamminga, Menno, Mutsaers, Pim G. N. J., Schol-Gelok, Suzanne, Dijkstra-Tiekstra, Margriet, Sidorenkov, Grigory, Vincenten, Julien, van Geffen, Wouter H., Knoester, Marjolein, Kosterink, Jos, Gans, Reinold, Stegeman, Coen, Huls, Gerwin, van Meerten, Tom
Publicado 2022

Proteogenomic Landscape of Breast Cancer Tumorigenesis and Targeted Therapy

por Krug, Karsten, Jaehnig, Eric J., Satpathy, Shankha, Blumenberg, Lili, Karpova, Alla, Anurag, Meenakshi, Miles, George, Mertins, Philipp, Geffen, Yifat, Tang, Lauren C., Heiman, David I., Cao, Song, Maruvka, Yosef E., Lei, Jonathan T., Huang, Chen, Kothadia, Ramani B., Colaprico, Antonio, Birger, Chet, Wang, Jarey, Dou, Yongchao, Wen, Bo, Shi, Zhiao, Liao, Yuxing, Wiznerowicz, Maciej, Wyczalkowski, Matthew A., Chen, Xi Steven, Kennedy, Jacob J., Paulovich, Amanda G., Thiagarajan, Mathangi, Kinsinger, Christopher R., Hiltke, Tara, Boja, Emily S., Mesri, Mehdi, Robles, Ana I., Rodriguez, Henry, Westbrook, Thomas F., Ding, Li, Getz, Gad, Clauser, Karl R., Fenyö, David, Ruggles, Kelly V., Zhang, Bing, Mani, D.R., Carr, Steven A., Ellis, Matthew J., Gillette, Michael A.
Publicado 2020

Platelet function is modified by common sequence variation in megakaryocyte super enhancers

por Petersen, Romina, Lambourne, John J., Javierre, Biola M., Grassi, Luigi, Kreuzhuber, Roman, Ruklisa, Dace, Rosa, Isabel M., Tomé, Ana R., Elding, Heather, van Geffen, Johanna P., Jiang, Tao, Farrow, Samantha, Cairns, Jonathan, Al-Subaie, Abeer M., Ashford, Sofie, Attwood, Antony, Batista, Joana, Bouman, Heleen, Burden, Frances, Choudry, Fizzah A., Clarke, Laura, Flicek, Paul, Garner, Stephen F., Haimel, Matthias, Kempster, Carly, Ladopoulos, Vasileios, Lenaerts, An-Sofie, Materek, Paulina M., McKinney, Harriet, Meacham, Stuart, Mead, Daniel, Nagy, Magdolna, Penkett, Christopher J., Rendon, Augusto, Seyres, Denis, Sun, Benjamin, Tuna, Salih, van der Weide, Marie-Elise, Wingett, Steven W., Martens, Joost H., Stegle, Oliver, Richardson, Sylvia, Vallier, Ludovic, Roberts, David J., Freson, Kathleen, Wernisch, Lorenz, Stunnenberg, Hendrik G., Danesh, John, Fraser, Peter, Soranzo, Nicole, Butterworth, Adam S., Heemskerk, Johan W., Turro, Ernest, Spivakov, Mikhail, Ouwehand, Willem H., Astle, William J., Downes, Kate, Kostadima, Myrto, Frontini, Mattia
Publicado 2017

Two high-risk susceptibility loci at 6p25.3 and 14q32.13 for Waldenström macroglobulinemia

por McMaster, Mary L., Berndt, Sonja I., Zhang, Jianqing, Slager, Susan L., Li, Shengchao Alfred, Vajdic, Claire M., Smedby, Karin E., Yan, Huihuang, Birmann, Brenda M., Brown, Elizabeth E., Smith, Alex, Kleinstern, Geffen, Fansler, Mervin M., Mayr, Christine, Zhu, Bin, Chung, Charles C., Park, Ju-Hyun, Burdette, Laurie, Hicks, Belynda D., Hutchinson, Amy, Teras, Lauren R., Adami, Hans-Olov, Bracci, Paige M., McKay, James, Monnereau, Alain, Link, Brian K., Vermeulen, Roel C. H., Ansell, Stephen M., Maria, Ann, Diver, W. Ryan, Melbye, Mads, Ojesina, Akinyemi I., Kraft, Peter, Boffetta, Paolo, Clavel, Jacqueline, Giovannucci, Edward, Besson, Caroline M., Canzian, Federico, Travis, Ruth C., Vineis, Paolo, Weiderpass, Elisabete, Montalvan, Rebecca, Wang, Zhaoming, Yeager, Meredith, Becker, Nikolaus, Benavente, Yolanda, Brennan, Paul, Foretova, Lenka, Maynadie, Marc, Nieters, Alexandra, de Sanjose, Silvia, Staines, Anthony, Conde, Lucia, Riby, Jacques, Glimelius, Bengt, Hjalgrim, Henrik, Pradhan, Nisha, Feldman, Andrew L., Novak, Anne J., Lawrence, Charles, Bassig, Bryan A., Lan, Qing, Zheng, Tongzhang, North, Kari E., Tinker, Lesley F., Cozen, Wendy, Severson, Richard K., Hofmann, Jonathan N., Zhang, Yawei, Jackson, Rebecca D., Morton, Lindsay M., Purdue, Mark P., Chatterjee, Nilanjan, Offit, Kenneth, Cerhan, James R., Chanock, Stephen J., Rothman, Nathaniel, Vijai, Joseph, Goldin, Lynn R., Skibola, Christine F., Caporaso, Neil E.
Publicado 2018