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  1. 29701
    “…BACKGROUND: A large prospective study in patients with type 2 diabetes (T2D), the German D2C cohort, is presently being enumerated to investigate risk factors of incident cancer in diabetic patients. …”
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    Cancer incidence in type 2 diabetes patients - first results from a feasibility study of the D2C cohort
  2. 29702
    “…RESULTS: Madin-Darby canine kidney cells, commonly used for the isolation and propagation of the influenza virus, were infected with an avian influenza viral strain A/chicken/German/N/49(H10N7) (H10/chicken) or a human influenza viral strain A/Osaka/981/98(H3N2) (H3/Osaka) virus. …”
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    Novel antiviral activity of neuraminidase inhibitors against an avian influenza a virus
  3. 29703
    “…Setting 40 preschool classes in areas with a high migrant population in the German and French speaking regions of Switzerland. …”
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    Effect of multidimensional lifestyle intervention on fitness and adiposity in predominantly migrant preschool children (Ballabeina): cluster randomised controlled trial
  4. 29704
    por Tony, Hans-Peter, Burmester, Gerd, Schulze-Koops, Hendrik, Grunke, Mathias, Henes, Joerg, Kötter, Ina, Haas, Judith, Unger, Leonore, Lovric, Svjetlana, Haubitz, Marion, Fischer-Betz, Rebecca, Chehab, Gamal, Rubbert-Roth, Andrea, Specker, Christof, Weinerth, Jutta, Holle, Julia, Müller-Ladner, Ulf, König, Ramona, Fiehn, Christoph, Burgwinkel, Philip, Budde, Klemens, Sörensen, Helmut, Meurer, Michael, Aringer, Martin, Kieseier, Bernd, Erfurt-Berge, Cornelia, Sticherling, Michael, Veelken, Roland, Ziemann, Ulf, Strutz, Frank, von Wussow, Praxis, Meier, Florian MP, Hunzelmann, Nico, Schmidt, Enno, Bergner, Raoul, Schwarting, Andreas, Eming, Rüdiger, Hertl, Michael, Stadler, Rudolf, Schwarz-Eywill, Michael, Wassenberg, Siegfried, Fleck, Martin, Metzler, Claudia, Zettl, Uwe, Westphal, Jens, Heitmann, Stefan, Herzog, Anna L, Wiendl, Heinz, Jakob, Waltraud, Schmidt, Elvira, Freivogel, Klaus, Dörner, Thomas
    Publicado 2011
    “…METHODS: Patients who received rituximab having shown an inadequate response to standard-of-care had their safety and clinical outcomes data retrospectively analysed as part of the German Registry of Autoimmune Diseases. The main outcome measures were safety and clinical response, as judged at the discretion of the investigators. …”
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    Safety and clinical outcomes of rituximab therapy in patients with different autoimmune diseases: experience from a national registry (GRAID)
  5. 29705
    “…Patients were randomised to either (1) a novel care pathway including diagnosis of ‘diseased’ QoL (any QoL measure below 50 points) using a QoL profile and expert report sent to the patient's coordinating practitioner, who arranged QoL therapy consisting of up to five standardised treatments for specific QoL defects or (2) standard postoperative care adhering to the German national guideline for breast cancer. The primary end point was the proportion of patients in each group with diseased QoL 6 months after surgery. …”
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    Direct improvement of quality of life using a tailored quality of life diagnosis and therapy pathway: randomised trial in 200 women with breast cancer
  6. 29706
    “…METHODOLOGY/PRINCIPAL FINDINGS: Primers were designed using a novel alignment-free strategy against eleven draft whole genome assemblies of E. coli O104:H4 German outbreak isolates from the E. coli O104:H4 Genome Analysis Crowd-Sourcing Consortium website, and a negative sequence set containing 69 E. coli chromosome and plasmid sequences from public databases. …”
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    Alignment-Free Design of Highly Discriminatory Diagnostic Primer Sets for Escherichia coli O104:H4 Outbreak Strains
  7. 29707
    “…METHODS: The data of 42,248 patients taken from the trauma registry of the German Association for Trauma Surgery (Deutsche Gesellschaft für Unfallchirurgie (DGU)) were analyzed. …”
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    Prehospital intubation of the moderately injured patient: a cause of morbidity? A matched-pairs analysis of 1,200 patients from the DGU Trauma Registry
  8. 29708
    “…The aim of this observational study was to describe and evaluate the association between MRSA incidence densities (IDs) and screening and control measures in ICUs participating in the German Nosocomial Infection Surveillance System. METHODS: The surveillance module for multidrug-resistant bacteria collects data on MRSA cases in ICUs with the aim to provide a national reference and a tool for evaluation of infection control management. …”
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    Screening and control of methicillin-resistant Staphylococcus aureus in 186 intensive care units: different situations and individual solutions
  9. 29709
    “…INTRODUCTION: Cardiac arrest following trauma occurs infrequently compared with cardiac aetiology. Within the German Resuscitation Registry a traumatic cause is documented in about 3% of cardiac arrest patients. …”
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    Cardiopulmonary resuscitation traumatic cardiac arrest - there are survivors. An analysis of two national emergency registries
  10. 29710
    “…In contrast to the typically researched risk factors, which increase the probability of pain generalization, this study also focus intensively on protective factors, which decrease the probability of pain generalization. TRIAL REGISTRATION: German Clinical Trial Register DRKS00003123…”
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    Study protocol: Transition from localized low back pain to chronic widespread pain in general practice: Identification of risk factors, preventive factors and key elements for treatment – A cohort study
  11. 29711
    “…RESEARCH DESIGN AND METHODS: The Study of Health in Pomerania (SHIP) is a population-based stratified sample of German men and women. Healthy participants and those determined to have T2DM arose from the SHIP cohort, and T1DM participants were recruited from diabetes clinics in the catchment area that gave rise to SHIP. …”
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    The Influence of Type 1 and Type 2 Diabetes on Periodontal Disease Progression: Prospective results from the Study of Health in Pomerania (SHIP)
  12. 29712
    “…Benefit-cost ratios and cost-effectiveness were evaluated from the perspective of the German Statutory Health Insurance as well as from social perspective. …”
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    Potential cost-effectiveness and benefit-cost ratios of adult pneumococcal vaccination in Germany
  13. 29713
    “…Implementation was via a “partial exemption” covering 80% of the costs. In 2008 the German NGO HELP launched a pilot project in two health districts to eliminate the remaining 20% of user fees. …”
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    User fee exemptions and excessive household spending for normal delivery in Burkina Faso: the need for careful implementation
  14. 29714
    “…The expression patterns of fetal mammary complexes obtained at 63 and 91 days post conception (dpc) from German Landrace (GL) and Pietrain (PI) were analyzed by Affymetrix GeneChip Porcine Genome Arrays. …”
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    Gene expression analysis of mammary tissue during fetal bud formation and growth in two pig breeds – indications of prenatal initiation of postnatal phenotypic differences
  15. 29715
    “…The study included two replication cohorts of North American (CD: n = 684; controls: n = 1440) and of German origin (CD: n = 1098; controls: n = 1048). …”
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    PTGER4 Expression-Modulating Polymorphisms in the 5p13.1 Region Predispose to Crohn's Disease and Affect NF-κB and XBP1 Binding Sites
  16. 29716
    por Tarnutzer, Silvan, Bopp, Matthias
    Publicado 2012
    “…METHODS: We compared age-specific and age-standardized mortality rates and hazard ratios (adjusted for education, marital status, language region and period) for Swiss and Italian nationals registered in the Swiss National Cohort (SNC), living in the German- or French-speaking part of Switzerland and falling into the age range 40–89 during the observation period 1990–2008. …”
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    Healthy migrants but unhealthy offspring? A retrospective cohort study among Italians in Switzerland
  17. 29717
    “…TRIAL REGISTRATION: Current Controlled Trials ISRCTN40484777 German Clinical Trial Register DRKS00000409…”
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    INTERBED: internet-based guided self-help for overweight and obese patients with full or subsyndromal binge eating disorder. A multicenter randomized controlled trial
  18. 29718
    “…METHODS: We adapted a HPV dynamic transmission model, which has been used in other countries, to the German context. The model was used to compare a cervical cancer screening only strategy with a strategy of combining vaccination of females aged 12–17 years old and cervical cancer screening, based on the current recommendations in Germany. …”
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    Cost-effectiveness of vaccination with a quadrivalent HPV vaccine in Germany using a dynamic transmission model
  19. 29719
    “…Present trauma algorithms recommend early hemorrhage control and massive fluid resuscitation. By matching the German Pelvic Injury Register (PIR) with the TraumaRegister DGU (TR) for the first time, we attempt to assess the initial fluid management for different Tile/OTA types of pelvic-ring fractures. …”
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    Acute management and outcome of multiple trauma patients with pelvic disruptions
  20. 29720
    “…Our aim was to analyse if the care dependency of nursing home residents influence their HRQOL and to describe HRQOL of nursing home residents at the time of admission. METHOD: Eleven German nursing homes were randomly selected for a cross-sectional multicentre study from April 2008 until December 2009. …”
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    Does the care dependency of nursing home residents influence their health-related quality of life?-A cross-sectional study
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