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  1. 30801
    “…Direct process costs from the health care providers' perspective were estimated according to the German DRG calculation framework. The health economic evaluation was based on margiual cost-effectveness ratios (MCERs); an individual marginal cost effectiveness relation ≤ 100 € per % WOMAC index increase was considered as primary endpoint of the confirmatory cohort comparison. …”
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    Cost effectiveness of total knee arthroplasty from a health care providers' perspective before and after introduction of an interdisciplinary clinical pathway - is investment always improvement?
  2. 30802
    “…This analysis presents data from the German subgroup of protease inhibitor (PI)-pretreated, but SQV-naïve patients. …”
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    Safety and efficacy after switch to a saquinavir-containing antiretroviral regimen in protease inhibitor pretreated HIV-positive patients
  3. 30803
    “…STUDY DESIGN: In a retrospective, multicenter study using data derived from the Trauma Registry of the German Trauma Society (2002-2006), we identified the most relevant prognostic factors from the patients basic data (P), prehospital phase (A), early (B1), and late (B2) trauma room phase. …”
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    The sequential trauma score - a new instrument for the sequential mortality prediction in major trauma*
  4. 30804
    “…Between June and December 2008, we recruited participants at a Rehabilitation Centre in the German-speaking part of Switzerland. RESULTS: To cope with pain, patients prefer passive strategies, which are not in line with recommended coping strategies. …”
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    A qualitative study on the role of cultural background in patients' perspectives on rehabilitation
  5. 30805
    “…We used the literature and bivariate analyses to identify candidate predictors, and multivariate logistic regression was used to develop a clinical prediction rule for CWS. We used data from a German cohort (n = 1212) for external validation. …”
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    Development and validation of a clinical prediction rule for chest wall syndrome in primary care
  6. 30806
    por Kivimäki, Mika, Nyberg, Solja T, Batty, G David, Fransson, Eleonor I, Heikkilä, Katriina, Alfredsson, Lars, Bjorner, Jakob B, Borritz, Marianne, Burr, Hermann, Casini, Annalisa, Clays, Els, De Bacquer, Dirk, Dragano, Nico, Ferrie, Jane E, Geuskens, Goedele A, Goldberg, Marcel, Hamer, Mark, Hooftman, Wendela E, Houtman, Irene L, Joensuu, Matti, Jokela, Markus, Kittel, France, Knutsson, Anders, Koskenvuo, Markku, Koskinen, Aki, Kouvonen, Anne, Kumari, Meena, Madsen, Ida EH, Marmot, Michael G, Nielsen, Martin L, Nordin, Maria, Oksanen, Tuula, Pentti, Jaana, Rugulies, Reiner, Salo, Paula, Siegrist, Johannes, Singh-Manoux, Archana, Suominen, Sakari B, Väänänen, Ari, Vahtera, Jussi, Virtanen, Marianna, Westerholm, Peter JM, Westerlund, Hugo, Zins, Marie, Steptoe, Andrew, Theorell, Töres
    Publicado 2012
    “…FUNDING: Finnish Work Environment Fund, the Academy of Finland, the Swedish Research Council for Working Life and Social Research, the German Social Accident Insurance, the Danish National Research Centre for the Working Environment, the BUPA Foundation, the Ministry of Social Affairs and Employment, the Medical Research Council, the Wellcome Trust, and the US National Institutes of Health.…”
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    Job strain as a risk factor for coronary heart disease: a collaborative meta-analysis of individual participant data
  7. 30807
    “…In the present analysis, we sought to evaluate the potential association of HFSR and survival in German patients with metastatic colorectal cancer and locally advanced rectal cancer treated with cape in clinical trials. …”
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    Capecitabine-associated hand–foot–skin reaction is an independent clinical predictor of improved survival in patients with colorectal cancer
  8. 30808
    “…The aim of this analysis was twofold: First, to explore to what extend German primary care physicians already get support by HIT and non-physician practice staff, and second, to show possible future perspectives. …”
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    Technical support and delegation to practice staff – status quo and (possible) future perspectives for primary health care in Germany
  9. 30809
    “…METHODS: We analysed data from the ‘German Health Update’ (GEDA10) telephone survey (n=22,050) and a smaller GEDA10-follow-up survey (n=2,493), which were both representative of the general population aged ≥18 years living in Germany. …”
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    Barriers to pandemic influenza vaccination and uptake of seasonal influenza vaccine in the post-pandemic season in Germany
  10. 30810
    “…The aim of this study was to determine the ratio of n-3/n-6 including the contents of EPA and DHA in fish fillets and fish products from the German market (n=123). Furthermore, the study focussed on the FA content in farmed salmon compared to wild salmon as well as in processed Alaska pollock fillet, e.g., fish fingers. …”
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    Survey of n-3 and n-6 polyunsaturated fatty acids in fish and fish products
  11. 30811
    “…TRIAL REGISTRATION NUMBER: German Clinical Trial Register DRKS00003427…”
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    Caries preventive efficacy of silver diammine fluoride (SDF) and ART sealants in a school-based daily fluoride toothbrushing program in the Philippines
  12. 30812
    “…METHODS: We conducted a prospective observational study in medical ICU patients treated in a German university hospital. We performed 43 CVVHD runs using citrate for regional anticoagulation in 28 critically ill patients with decompensated liver cirrhosis or acute liver failure (maximum of two CVVHD runs per patient). …”
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    Continuous venovenous hemodialysis with regional citrate anticoagulation in patients with liver failure: a prospective observational study
  13. 30813
    “…CONCLUSIONS: In a real-life clinical setting, implementation of a PCT-protocol was associated with a reduced duration of antibiotic therapy in septic ICU patients without compromising clinical or economical outcomes. GERMAN CLINICAL TRIALS REGISTER: DRKS00003490…”
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    Procalcitonin-guided algorithm to reduce length of antibiotic therapy in patients with severe sepsis and septic shock
  14. 30814
    “…METHODS: The data for 67,782 patients from the TraumaRegister DGU(® )of the German Trauma Society were analyzed. The following inclusion criteria were applied: injury severity score ≥16 points, primary admission, age 1 to 15 years old, systolic blood pressure ≥20 mmHg at the accident site and transfusion of at least one unit of packed red blood cells (pRBC) in the emergency trauma room prior to intensive care admission. …”
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    Influence of prehospital volume replacement on outcome in polytraumatized children
  15. 30815
    “…TRIAL REGISTRATION: The trial protocol has been registered in the German Clinical Trials Register DRKS00004550.…”
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    DiaSurg 2 trial - surgical vs. medical treatment of insulin-dependent type 2 diabetes mellitus in patients with a body mass index between 26 and 35 kg/m(2): study protocol of a randomized controlled multicenter trial - DRKS00004550
  16. 30816
    “…METHODS: Data were obtained from the German Health Interview and Examination Survey for Children and Adolescents (KiGGS) conducted by the Robert Koch Institute (2003–2006). 17,450 randomly selected children aged 0–17 years took part in the drug interviews. …”
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    Off-label medicine use in children and adolescents: results of a population-based study in Germany
  17. 30817
    “…METHODS: 1,510 outpatients aged 1-75 years, starting anthroposophic treatment for chronic conditions in routine German outpatient settings, participated in a prospective cohort study. …”
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    Long-term outcomes of anthroposophic treatment for chronic disease: a four-year follow-up analysis of 1510 patients from a prospective observational study in routine outpatient settings
  18. 30818
    “…We analyzed data from the German MARIEplus study, a large prospective population-based cohort of patients aged 50 and older, who were diagnosed with breast cancer between 2001 and 2005. …”
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    Mortality and Recurrence Risk in Relation to the Use of Lipid-Lowering Drugs in a Prospective Breast Cancer Patient Cohort
  19. 30819
    “…Most of the available data, however, relies on subjective reports; there is limited objective data on physical activity (PA) levels in German primary school children. The purpose of this study, therefore, was to accurately determine how much time children spend undertaking different intensities of PA and being sedentary during weekdays and weekend using objective assessment tools. …”
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    Objectively determined physical activity levels of primary school children in south-west Germany
  20. 30820
    por Wilke, Michael, Grube, Rolf
    Publicado 2013
    “…The current guidelines of the American Thoracic Society, the treatment recommendations of the Paul-Ehrlich-Gesellschaft (PEG), the guidelines from the British Society for Antimicrobial Chemotherapy, the VAP guideline of the Canadian Critical Care trials group, as well as the new German S3-guideline for HAP were examined. RESULTS: All guidelines are based on grading systems that assess the evidence underlying the recommendations. …”
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    Update on management options in the treatment of nosocomial and ventilator assisted pneumonia: review of actual guidelines and economic aspects of therapy
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