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31241por Meister, Franziska Alexandra, Lurje, Georg, Verhoeven, Suekran, Wiltberger, Georg, Heij, Lara, Liu, Wen-Jia, Jiang, Decan, Bruners, Philipp, Lang, Sven Arke, Ulmer, Tom Florian, Neumann, Ulf Peter, Bednarsch, Jan, Czigany, Zoltan“…The data of 100 consecutive patients who underwent partial hepatectomy for hepatocellular carcinoma (HCC) at a German university medical centre were retrospectively analysed (May 2008–December 2019). …”
Publicado 2022
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31242por Hebestreit, Helge, Zeidler, Cornelia, Schippers, Christopher, de Zwaan, Martina, Deckert, Jürgen, Heuschmann, Peter, Krauth, Christian, Bullinger, Monika, Berger, Alexandra, Berneburg, Mark, Brandstetter, Lilly, Deibele, Anna, Dieris-Hirche, Jan, Graessner, Holm, Gündel, Harald, Herpertz, Stephan, Heuft, Gereon, Lapstich, Anne-Marie, Lücke, Thomas, Maisch, Tim, Mundlos, Christine, Petermann-Meyer, Andrea, Müller, Susanne, Ott, Stephan, Pfister, Lisa, Quitmann, Julia, Romanos, Marcel, Rutsch, Frank, Schaubert, Kristina, Schubert, Katharina, Schulz, Jörg B., Schweiger, Susann, Tüscher, Oliver, Ungethüm, Kathrin, Wagner, Thomas O. F., Haas, Kirsten“…METHODS: Two cohorts of 682 patients each are sequentially recruited from 11 university-based German Centers for Rare Diseases (CRD): the standard care cohort (control, somatic expertise only) and the innovative care cohort (experimental, combined somatic and mental health expertise). …”
Publicado 2022
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31243por Scholz, Stefan, Schwarz, Magdalena, Beck, Ekkehard, Meszaros, Kinga, Schneider, Melanie, Ultsch, Bernhard, Greiner, Wolfgang“…The model included the latest real-world evidence on vaccine effectiveness, the comprehensive burden of disease on patients (sequelae) and their family (quality of life impact), comprehensive German IMD costs, and vaccination uptake assumptions. …”
Publicado 2021
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31244“…The analysis was based on a population-representative survey of the German population aged 18–69 years (N = 5,135 respondents, comprising a subgroup of n = 1,038 persons suffering from depression and n = 598 persons who spent the lockdown primarily in home isolation). …”
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31245por Maurer, Tabea, Belau, Matthias Hans, von Grundherr, Julia, Schlemmer, Zoe, Patra, Stefan, Becher, Heiko, Schulz, Karl-Heinz, Zyriax, Birgit-Christiane, Schmalfeldt, Barbara, Chang-Claude, Jenny“…PARTICIPANTS: Eligibility criteria included women ≥18 years of age, diagnosed with ovarian cancer, tubal cancer or peritoneal cancer and primary or interval debulking, scheduled but not started adjuvant or neoadjuvant chemotherapy and sufficient German-language skills. INTERVENTION: The IG received a 12-month exercise and nutrition programme, the CG continued to follow usual care. …”
Publicado 2022
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31246por Flinspach, Armin Niklas, Herrmann, Eva, Raimann, Florian Jürgen, Zacharowski, Kai, Adam, Elisabeth Hannah“…This study will be conducted as a prospective, randomised, controlled, single-blinded, monocentre trial at a German university hospital in consenting adult patients undergoing heart valve surgery at a university hospital. …”
Publicado 2022
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31247por Loosen, Sven H., Roderburg, Christoph, Jördens, Markus S., Fluegen, Georg, Luedde, Tom, Kostev, Karel“…SIMPLE SUMMARY: By analyzing a large German primary care provider database, we demonstrated that obesity represents a decisive risk factor for the development of colon, rectal, and liver cancer, partly in a sex-dependent manner. …”
Publicado 2022
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31248por Dathan-Stumpf, Anne, Rieger, Anna, Verlohren, Stefan, Wolf, Cyrill, Stepan, Holger“…METHODS AND FINDINGS: This retrospective analysis compared data from the German population of a multicentre clinical study (PROGNOSIS, n = 203; sFlt-1/PlGF ratio blinded and unavailable for decision-making) with RWD from University Hospital Leipzig, Germany (n = 281; sFlt-1/PlGF ratio used to guide clinical decision-making). …”
Publicado 2022
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31249por Pfäfflin, Frieder, Stegemann, Miriam Songa, Heim, Katrin Moira, Achterberg, Stephan, Pfitzner, Ursula, Götze, Louise, Oesterhelweg, Lars, Suttorp, Norbert, Herzog, Christian, Stadtmann, Benjamin, Uhrig, Alexander“…Although the SARS-CoV-2 pandemic interfered with our activities the enhanced cooperation among German HLIU during the pandemic ensured constant readiness for the admission of HCID patients to our or to collaborating HLIU. …”
Publicado 2022
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31250por Knitza, Johannes, Muehlensiepen, Felix, Ignatyev, Yuriy, Fuchs, Franziska, Mohn, Jacob, Simon, David, Kleyer, Arnd, Fagni, Filippo, Boeltz, Sebastian, Morf, Harriet, Bergmann, Christina, Labinsky, Hannah, Vorbrüggen, Wolfgang, Ramming, Andreas, Distler, Jörg H. W., Bartz-Bazzanella, Peter, Vuillerme, Nicolas, Schett, Georg, Welcker, Martin, Hueber, Axel J.“…MATERIALS AND METHODS: Patients newly presenting to three German secondary rheumatology outpatient clinics were randomly assigned in a 1:1 ratio to complete consecutively Ada or Rheport in a prospective non-blinded multicentre controlled crossover randomized trial. …”
Publicado 2022
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31251Cardiovascular Risks and Risk Stratification in Inflammatory Joint Diseases: A Cross-Sectional Study“…CV risk in the Middle-European patients with IJD was higher than in the German general population (p = 0.004), and similar to the Norwegian patients with IJD, although patients with Middle-European PsA were at higher risk than the Norwegian patients (p = 0.045). …”
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31252por Basinska, Kornelia, Zúñiga, Franziska, Simon, Michael, De Geest, Sabina, Guerbaai, Raphaëlle Ashley, Wellens, Nathalie I. H., Nicca, Dunja, Brunkert, Thekla“…SETTING: Eleven nursing homes in the German-speaking region of Switzerland. PARTICIPANTS: Quantitative data were collected from 573 care workers; qualitative data were collected from 108 care workers and the leadership from 11 nursing homes. …”
Publicado 2022
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31253por Fuchshuber, Jürgen, Jauk, Emanuel, Hiebler-Ragger, Michaela, Unterrainer, Human Friedrich“…This led to the construction of a 12-item (L-12) version and a 5-item version (L-5), which were assessed in a second sample consisting of 371 German-speaking healthy adults (58.50% female) aged 18–69 years (M = 28; SD = 9.75). …”
Publicado 2022
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31254“…METHOD: We conducted a systematic literature search in PubMed, including studies published in English or German between 1985 and 2020. The population of each study had to consist of at least 75% childhood cancer survivors (CCSs) who had completed the cancer treatment at least twelve months before late effects were assessed and who had received HD-MTX. …”
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31255por Wittekind, Charlotte E., Takano, Keisuke, Sckopke, Philipp, Winkler, Markus H., Werner, Gabriela G., Ehring, Thomas, Rüther, Tobias“…Additionally, it is the first study to systematically investigate potential mechanisms mediating the effects of treatment on clinical outcome. TRIAL REGISTRATION: German Clinical Trials Register, DRKS00019221, 11/11/2019 SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s13063-022-06155-6.…”
Publicado 2022
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31256“…BACKGROUND: The German health care system is faced with a serious shortage of nurses. …”
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31257por Seibert, Felix S., Blazquez-Navarro, Arturo, Hölzer, Bodo, Doevelaar, Adrian A. N., Nusshag, Christian, Merle, Uta, Morath, Christian, Zgoura, Panagiota, Dittmer, Rita, Schneppenheim, Sonja, Wilhelm, Jochen, Babel, Nina, Budde, Ulrich, Westhoff, Timm H.“…We investigated 25 patients, who were on mechanical ventilation for COVID-19 pneumonia with ARDS at two German university hospitals. All patients received PLEX as an ultima ratio measure for refractory ARDS. …”
Publicado 2022
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31258por Sprenger, Ralf, Häckl, Dennis, Kossack, Nils, Schiffner-Rohe, Julia, Wohlleben, Jessica, von Eiff, Christof“…BACKGROUND: Pneumococcal vaccination is recommended by the German Standing Committee on Vaccination (STIKO) for infants, elderly 60+ years and patients at risk. …”
Publicado 2022
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31259por Rühle, Alexander, Wiedenmann, Nicole, Fennell, Jamina T., Mix, Michael, Ruf, Juri, Stoian, Raluca, Thomsen, Andreas R., Vaupel, Peter, Baltas, Dimos, Grosu, Anca-L., Nicolay, Nils H.“…TRIAL REGISTRATION: The prospective trial was registered in the German Clinical Trial Register (DRKS00003830). Registered 20 August 2015 SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s00259-021-05602-x.…”
Publicado 2021
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31260por Gaede, Luise, Blumenstein, Johannes, Eckel, Clemens, Grothusen, Christina, Tiyerili, Vedat, Sötemann, Dagmar, Nef, Holger, Elsässer, Albrecht, Achenbach, Stephan, Möllmann, Helge“…Expected mortality was calculated with the annually revised German Aortic valve score (AKL-score) based on the data of either catheter-based (AKL-CATH) or isolated surgical (AKL-CHIR) aortic valve replacement in Germany from the previous year (2019). …”
Publicado 2022
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