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  1. 31741
    “…We investigated the feasibility of a weekly WQ assessing symptoms of ARI and GII among participants of the German National Cohort (GNC). MATERIAL AND METHODS: In the study centres Hamburg and Bremen of the GNC participants of the Pretest 1 phase (September to November 2011) were invited to additionally take part in this feasibility study testing the WQ. …”
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    Web-based questionnaires to capture acute infections in long-term cohorts: Findings of a feasibility study
  2. 31742
    “…Further randomized controlled trials are needed in larger populations and to investigate the long-term outcome. TRIAL REGISTRATION: German Register for Clinical Trials, registration number DRKS00003067; http://drks-neu.uniklinik-freiburg.de/drks_web/navigate.do?…”
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    Effects of a Guided Web-Based Smoking Cessation Program With Telephone Counseling: A Cluster Randomized Controlled Trial
  3. 31743
    “…CONCLUSIONS: The proportion of TDR was similar but the proportion of HIV-1 subtype non-B infections was higher as previously described for Germany based on results from the German HIV-1 Seroconverter Cohort [1,2]. This difference could be the result of a broadened inclusion of HET and IDUs due to the sampling method used making this study representative for molecular surveillance of HIV-1 in Germany.…”
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    Analysis of transmitted drug resistance and HIV-1 subtypes using dried serum spots of recently HIV-infected individuals in 2013 in Germany
  4. 31744
    “…Tropism testing was done from proviral DNA with FPR cut-offs according to the German recommendations. RESULTS: In 2013, the patient harbouring a virus with high level resistance to all RTI and PI received a regimen containing FTC, TDF, DRV/r, RPV, T20, and RAL to handle a viral load of 5000 RNA copies/mL, but never achieved fully suppressed viral load. …”
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    New dolutegravir resistance pattern identified in a patient failing antiretroviral therapy
  5. 31745
    “…METHODS: A total of 832 and 944 patients from 23 German centres were under firstline therapy in 2012 and 2013, respectively. …”
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    Low level HIV viremia is more frequent under protease-inhibitor containing firstline therapy than under NNRTI-regimens
  6. 31746
    “…METHODS: To obtain a manufacturing license according to the German Medicinal Products Act, the enrichment of clinical-grade CMV-specific T cells from three healthy CMV-seropositive donors was performed aseptically under GMP conditions using the CliniMACS cytokine capture system (CCS) after restimulation with an overlapping peptide pool of the immunodominant CMVpp65 antigen. …”
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    Rapid generation of clinical-grade antiviral T cells: selection of suitable T-cell donors and GMP-compliant manufacturing of antiviral T cells
  7. 31747
    “…Vaccination coverage (VC) data were retrieved from a database of health insurance claims representing ~85% of the total German population. We applied the screening method to calculate influenza subtype-specific VE and compared our results with VE estimates from other observational studies in Europe. …”
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    Application of the screening method to monitor influenza vaccine effectiveness among the elderly in Germany
  8. 31748
    “…METHODS: Included in the study were 1190 patients with and 2864 patients without diabetes, aged 28-74 years, recruited from a German population-based AMI registry. Patients were consecutively hospitalized between 1 January 2000 and 31 December 2008 with a first ever AMI and followed up until December 2011. …”
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    Association of obesity and long-term mortality in patients with acute myocardial infarction with and without diabetes mellitus: results from the MONICA/KORA myocardial infarction registry
  9. 31749
    “…METHODS: This was a 3-year, open-label, observational study evaluating data from women undergoing COS for assisted reproductive technology at 31 German fertility centers. Physicians stated their recommended r-hFSH starting dose, then generated a CONSORT-recommended r-hFSH starting dose. …”
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    Individualized recombinant human follicle-stimulating hormone dosing using the CONSORT calculator in assisted reproductive technology: a large, multicenter, observational study of routine clinical practice
  10. 31750
    “…Vaccination formulations used were PCV7 (from July 2006), PCV10 (from April 2009) and PCV13 (from December 2009, replacing PCV7). METHODS: The German National Reference Center for Streptococci (GNRCS) has conducted surveillance of IPD since 1992. …”
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    Increase of serotypes 15A and 23B in IPD in Germany in the PCV13 vaccination era
  11. 31751
    “…A considerable proportion of German men who have sex with men (MSM) infected with HIV have a CD4 cell count below 350 cells/μl at time of diagnosis and are thus defined as “late presenters”. …”
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    Recency and frequency of HIV testing among men who have sex with men in Germany and socio-demographic factors associated with testing behaviour
  12. 31752
    por Bidmon, Sonja, Terlutter, Ralf
    Publicado 2015
    “…METHODS: Gender differences were analyzed based on an empirical online survey of 1006 randomly selected German patients. The sample was drawn from an e-panel maintained by GfK HealthCare. …”
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    Gender Differences in Searching for Health Information on the Internet and the Virtual Patient-Physician Relationship in Germany: Exploratory Results on How Men and Women Differ and Why
  13. 31753
    “…Recent research has also served to lessen safety concerns regarding the use of kava due to hepatotoxic risk, which is reflected in a recent German court overturning the previous kava ban in that country (which may in turn influence a reinstatement by the European Union). …”
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    Kava for the treatment of generalised anxiety disorder (K-GAD): study protocol for a randomised controlled trial
  14. 31754
    “…RESULTS: A total of 1,530 patients were documented in 258 German medical practices. A total of 1,301 patients were included in the full analysis set (55% male, 45% female; age median 64 years; body mass index median 30.8 kg/m(2); pre-BOT: n=1,072; pre-SIT: n=229), and 1,515 patients were evaluated for safety. …”
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    Effectiveness and tolerability of treatment intensification to basal–bolus therapy in patients with type 2 diabetes on previous basal insulin-supported oral therapy with insulin glargine or supplementary insulin therapy with insulin glulisine: the PARTNER observational study
  15. 31755
    “…Due to a combination of low stopping power and limited spatial resolution (caused by limited light output of the scintillators), these systems could not compete with bismuth germanate (BGO)-based PET scanners. Developments on TOF system were limited for about a decade but started again around 2000. …”
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    Recent developments in time-of-flight PET
  16. 31756
    “…Children were categorized to normal-weight (≥3(rd) and <90(th) percentile; n = 6458), overweight (≥90(rd) and <97(th) percentile; n = 746) or obese (>97(th) percentile; n = 371) according to the German reference system that is based on age and gender-specific body mass indices (BMI). …”
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    Influence of Obesity on Foot Loading Characteristics in Gait for Children Aged 1 to 12 Years
  17. 31757
    “…METHODS: One thousand one hundred twenty-one German UC patients and 1770 healthy controls were initially screened for rare deletions and duplications employing SNP-array data. …”
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    Genome-wide rare copy number variation screening in ulcerative colitis identifies potential susceptibility loci
  18. 31758
    “…OBJECTIVE: We investigated the association of residential road traffic noise with depressive symptoms using 5-year follow-up data from a German population-based study. METHODS: We analyzed data from 3,300 participants in the Heinz Nixdorf Recall study who were between 45 and 75 years old and were without depressive symptoms at baseline (2000–2003). …”
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    Residential Road Traffic Noise and High Depressive Symptoms after Five Years of Follow-up: Results from the Heinz Nixdorf Recall Study
  19. 31759
    “…TRIAL REGISTRATION: The trial was registered in the German Clinical Trials Register (DRKS00009684) on 27/11/2015. …”
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    Inflammasome and toll-like receptor signaling in human monocytes after successful cardiopulmonary resuscitation
  20. 31760
    “…The CG will receive one general training session about healthy nutrition in accordance with the recommendations of the German Society of Nutrition (standard of care in Germany) and the benefits of regular physical activity on health status. …”
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    Effects of lifestyle intervention in BRCA1/2 mutation carriers on nutrition, BMI, and physical fitness (LIBRE study): study protocol for a randomized controlled trial
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