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113101por Harrington, Richard A, Scarborough, Peter, Hodgkins, Charo, Raats, Monique M, Cowburn, Gill, Dean, Moira, Doherty, Aiden, Foster, Charlie, Juszczak, Edmund, Ni Mhurchu, Cliona, Winstone, Naomi, Shepherd, Richard, Timotijevic, Lada, Rayner, Mike“…METHODS: The intervention consisted of a website where participants could access tailored feedback on previous purchases of ready meals and pizzas, set goals for behavior change, and model and practice the recommended healthy shopping behavior using traffic light labels. …”
Publicado 2019
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113102por Pieri, Naira Caroline Godoy, Mançanares, Ana Carolina Furlanetto, de Souza, Aline Fernanda, Fernandes, Hugo, Diaza, Angela Maria Gonella, Bressan, Fabiana Fernandes, Roballo, Kelly Cristine Santos, Casals, Juliana Barbosa, Binelli, Mario, Ambrósio, Carlos Eduardo, dos Santos Martins, Daniele“…Although cell culture-related factors, such as the in vitro supplementation of hormonal factors, are known to promote successful xenotransplantation in mice, little is known about the influence of these factors on SSCs in vitro or in vivo in other mammalian species, such as dogs (Canis lupus familiaris). In this context, the goals of this study were to test the effect of follicle-stimulating hormone (FSH) on canine spermatogonial stem cell (cSSC) cultures since this hormone is related to the glial cell-derived neurotrophic factor (GDNF) signaling pathway, which is responsible for the self-renewal and maintenance of these cells in vivo, and to investigate the microenvironment of the SSC culture after FSH supplementation. …”
Publicado 2019
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113103“…The transtheoretical model was used as a framework for observing self-management behavior for the improvement of individual health, and the theory of planned behavior was used to evaluate personal goals, execution, outcome, and personal preferences. …”
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113104por Thomas, BJ, Fuller, Sarah, Ilanchezhian, Maran, Allen, Deborah, Allen, Taryn, Weiner, Lori, Wisch, Laura, Sherri, DePollar, Gillespie, Andy, Raygada, Margarita, Arnaldez, Fernanda, Reilly, Karlyne, Glod, John, Widemann, Brigitte, Del Rivero, Jaydira“…Methods: A prospective study has been developed at the NCI to comprehensively and longitudinally evaluate the natural history of patients with rare solid tumors or tumor predisposition syndromes. The goals of this study are to 1) estimate and define the clinical spectrum of rare cancers, 2) evaluate and follow biological relatives of patients with rare tumors or carriers of germline genetic variants that predispose to development of rare tumors, and 3) develop a better understanding of these diseases in an effort to a) develop novel therapeutic interventions, b) preventive/screening guidelines, c) endpoints for future clinical trials, and d) identify relevant patient reported outcomes that can improve our understanding of patients’ psychosocial and functional needs. …”
Publicado 2019
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113105“…As part of the United States Environmental Protection Agency’s National Wetland Condition Assessment (NWCA), we characterized the status of nonnative plants in wetlands across the conterminous United States (US). Our primary goals were to (1) document the composition of nonnative taxa at 1138 NWCA sites sampled in 2011 and (2) estimate the areal extent of wetland under stress from nonnative plants within the NWCA 2011 sampled population of ~ 25 million ha of wetland (represented by 967 sampled probability sites and the NWCA survey design). …”
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113106por Kunz, Regina, von Allmen, David Y., Marelli, Renato, Hoffmann-Richter, Ulrike, Jeger, Joerg, Mager, Ralph, Colomb, Etienne, Schaad, Heinz J., Bachmann, Monica, Vogel, Nicole, Busse, Jason W., Eichhorn, Martin, Bänziger, Oskar, Zumbrunn, Thomas, de Boer, Wout E. L., Fischer, Katrin“…A societal discussion about achievable goals and readiness to consider procedural changes in WC evaluations may deserve considerations. …”
Publicado 2019
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113107por Young, Bonnie N., Peel, Jennifer L., Benka-Coker, Megan L., Rajkumar, Sarah, Walker, Ethan S., Brook, Robert D., Nelson, Tracy L., Volckens, John, L’Orange, Christian, Good, Nicholas, Quinn, Casey, Keller, Joshua P., Weller, Zachary D., Africano, Sebastian, Osorto Pinel, Anibal B., Clark, Maggie L.“…The primary health endpoints were blood pressure, C-reactive protein, and glycated hemoglobin. Overall study goals are to explore barriers and enablers of new cookstove adoption and sustained use, compare health endpoints by assigned cookstove type, and explore the exposure-response associations between PM(2.5) and indicators of cardiometabolic health. …”
Publicado 2019
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113108por Mease, Philip, Walsh, Jessica A., Baraliakos, Xenofon, Inman, Robert, de Vlam, Kurt, Wei, James Cheng-Chung, Hunter, Theresa, Gallo, Gaia, Sandoval, David, Zhao, Fangyi, Dong, Yan, Bolce, Rebecca, Marzo-Ortega, Helena“…An ASAS40 response is a high standard that is not routinely used in clinical practice. The goals of this study were (a) to measure improvement in ixekizumab-treated patients in the four ASAS treatment response domains and in other patient-reported outcomes, and (b) to determine how the ASAS response was associated with changes in spinal pain at night, fatigue, sleep, and the Short Form 36-Item Physical Component Summary (SF-36 PCS). …”
Publicado 2019
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113109por Smilkstein, Martin J., Pou, Sovitj, Krollenbrock, Alina, Bleyle, Lisa A., Dodean, Rozalia A., Frueh, Lisa, Hinrichs, David J., Li, Yuexin, Martinson, Thomas, Munar, Myrna Y., Winter, Rolf W., Bruzual, Igor, Whiteside, Samantha, Nilsen, Aaron, Koop, Dennis R., Kelly, Jane X., Kappe, Stefan H. I., Wilder, Brandon K., Riscoe, Michael K.“…CONCLUSIONS: Extrapolation of these results to humans predicts that ELQ-331 should be capable of meeting and far-exceeding currently published duration-of-effect goals for anti-malarial LAI-C. Furthermore, the distinctive pharmacokinetic profile of ELQ-300 after treatment with ELQ-331 may facilitate durable protection and enable protection for far longer than 3 months. …”
Publicado 2019
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113110por Singh, Devendra Raj, Harvey, Chloe M., Bohara, Pushpalata, Nath, Dhirendra, Singh, Sunita, Szabo, Sylvia, Karki, Kshitij“…Despite Nepal’s significant achievements in meeting the maternal and child health targets of the Millennium Development Goals, an estimated 23,000 Nepalese children under five years die every year, with three out of five babies dying within the first 28 days of life. …”
Publicado 2019
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113111por Sule, Gautam, Kelley, William J., Yalavarthi, Srilakshmi, Eniola-Adefeso, Omolola, Knight, Jason S.“…In its activated state, Mac-1 mediates cell-cell interactions by engaging a variety of surface molecules, including the endothelium-expressed glycoprotein ICAM-1. Here, our goals were (1) to determine the extent to which APS neutrophils adhere to healthy, resting endothelial cells under physiologic flow conditions, and (2) to identify potential therapeutic targets by elucidating the molecules required for that adhesion. …”
Publicado 2019
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113112por Flippin, Michelle“…The results of this investigation advance clinical practice in the ASD field by providing intervention data relating to the efficacy of father-implemented instructional programs on child communication goals.…”
Publicado 2018
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113113por Kwakernaak, Joyce, Eekhof, Just A H, De Waal, Margot W M, Barenbrug, Elisabeth A M, Chavannes, Niels H“…OBJECTIVE: This vignette-based experimental study aimed to explore what kind of Web-based search strategies are applied and how search strategies, demographic characteristics, and the quality of the visited websites relate to finding the right diagnosis. Additional goals were to describe how searching on the Web influences one’s perception of the severity of the potential diagnosis and whether or not the participants would discuss the information they found on the internet with their doctors. …”
Publicado 2019
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113114por Garcia, Erwin, Osté, Maryse C. J., Bennett, Dennis W., Jeyarajah, Elias J., Shalaurova, Irina, Gruppen, Eke G., Hazen, Stanley L., Otvos, James D., Bakker, Stephan J. L., Dullaart, Robin P.F., Connelly, Margery A.“…However, few studies have explored the association of betaine with incident T2DM, especially in the general population. The goals of this study were to evaluate the performance of a newly developed betaine assay and to prospectively explore the potential clinical associations of betaine and future risk of T2DM in a large population-based cohort. …”
Publicado 2019
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113115por Tsertsvadze, Tengiz, Gamkrelidze, Amiran, Nasrullah, Muazzam, Sharvadze, Lali, Morgan, Juliette, Shadaker, Shaun, Gvinjilia, Lia, Butsashvili, Maia, Metreveli, David, Kerashvili, Vakhtang, Ezugbaia, Marina, Chkhartishvili, Nikoloz, Abutidze, Akaki, Kvaratskhelia, Valeri, Averhoff, Francisco“…With introduction of next generation DAAs, significantly improved response rates are expected, paving the way for Georgia to achieve HCV elimination goals.…”
Publicado 2020
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113116por Quan, Amanda My Linh, Stiell, Ian, Perry, Jeffrey J, Paradis, Michelle, Brown, Erica, Gignac, Jordan, Wilson, Lindsay, Wilson, Kumanan“…The median TRI score for this group was 3.38, indicating a higher than average propensity to embrace and adopt new technologies to accomplish goals in their work or daily lives. The majority of respondents agreed or strongly agreed that the app helped participants accurately carry out the clinical rules (56/77, 73%) and that they would recommend this app to their colleagues (64/77, 83%). …”
Publicado 2020
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113117“…The proportion of the need for family planning satisfied by modern methods, Sustainable Development Goals (SDG) indicator 3.7.1, was 75.7% (95% UI 73.2%–78.0%) globally, yet less than half of the need for family planning was met in Middle and Western Africa. …”
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113118por Bautista-Herrera, LA, De la Cruz-Mosso, U, Román-Fernández, IV, Parra-Rojas, I, Soñanez-Organis, JG, Hernández-Bello, J, Morales-Zambrano, RA, Villanueva-Quintero, GD, Muñoz-Valle, JF“…The goals of our study were to determine the possible association of interleukin (IL)-31 with Th17 cytokine profile in serum and to quantify retinoic acid-related orphan receptor C (RORC) mRNA expression in psoriatic arthritis (PsA) patients. …”
Publicado 2020
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113119por Nauman, Javaid, Soteriades, Elpidoforos S, Hashim, Muhammad Jawad, Govender, Romona, Al Darmaki, Reem Saif, Al Falasi, Reem Juma, Ojha, Shreesh Kumar, Masood-Husain, Shamaila, Javaid, Syed Fahad, Khan, Moien AB“…The high burden of AEMT warrants the implementation of robust policies in the healthcare system including appropriate patient safety training for the healthcare professionals, and safe culture of feedback with the implementation of electronic medical records to achieve WHO patient safety strategy goals.…”
Publicado 2020
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113120“…Despite recent trends, preemption is not inherently adversarial to public health, equity, or good governance but rather reflects its wielder's goals and values. Existing frameworks for assessing preemption fail to reconcile its potential to both advance and hinder health equity. …”
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