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421por Fakhiri, Julia, Schneider, Marc A., Puschhof, Jens, Stanifer, Megan, Schildgen, Verena, Holderbach, Stefan, Voss, Yannik, El Andari, Jihad, Schildgen, Oliver, Boulant, Steeve, Meister, Michael, Clevers, Hans, Yan, Ziying, Qiu, Jianming, Grimm, Dirk“…Here, we largely expanded the repertoire of rAAV/BoV chimeras, by assembling packaging plasmids encoding the capsid genes of four additional primate bocaviruses, HBoV2–4 and GBoV (Gorilla BoV). Capsid protein expression and efficient rAAV cross-packaging were validated by immunoblotting and qPCR, respectively. …”
Publicado 2019
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422por Rangavittal, Samarth, Stopa, Natasha, Tomaszkiewicz, Marta, Sahlin, Kristoffer, Makova, Kateryna D., Medvedev, Paul“…We evaluate the performance of DiscoverY on human and gorilla genomes, across different sequencing platforms including Illumina, 10X, and PacBio. …”
Publicado 2019
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423por Cechova, Monika, Harris, Robert S, Tomaszkiewicz, Marta, Arbeithuber, Barbara, Chiaromonte, Francesca, Makova, Kateryna D“…To investigate their turnover in great apes, we studied satellite repeats of unit sizes up to 50 bp in human, chimpanzee, bonobo, gorilla, and Sumatran and Bornean orangutans, using unassembled short and long sequencing reads. …”
Publicado 2019
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424por Edsall, Lee E, Berrio, Alejandro, Majoros, William H, Swain-Lenz, Devjanee, Morrow, Shauna, Shibata, Yoichiro, Safi, Alexias, Wray, Gregory A, Crawford, Gregory E, Allen, Andrew S“…To illustrate, we applied our joint approach to DHS sites in fibroblast cells from five primates (human, chimpanzee, gorilla, orangutan, and rhesus macaque). We identified 89,744 DHS sites, of which 41% are identified as differential between species using the joint model compared with 33% using the conventional pairwise approach. …”
Publicado 2019
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425por Grunwald, Stefanie Anke, Popp, Oliver, Haafke, Stefanie, Jedraszczak, Nicole, Grieben, Ulrike, Saar, Kathrin, Patone, Giannino, Kress, Wolfram, Steinhagen-Thiessen, Elisabeth, Dittmar, Gunnar, Spuler, Simone“…Data and pathway analyses included GOrilla, Reactome and DAVID. We measured mevalonate intracellularly and analyzed eicosanoid profiles secreted by human muscle cells. …”
Publicado 2020
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426por Narat, Victor, Amato, Katherine R., Ranger, Noémie, Salmona, Maud, Mercier-Delarue, Séverine, Rupp, Stephanie, Ambata, Philippe, Njouom, Richard, Simon, François, Giles-Vernick, Tamara, LeGoff, Jérôme“…We conducted 16S ribosomal RNA gene sequencing to characterize intestinal microbiota of free-ranging sympatric chimpanzees and gorillas in southeastern Cameroon and sympatric chimpanzees and gorillas in a European zoo. …”
Publicado 2020
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427“…Data were analyzed using classical statistical methods and functional enrichment analysis software represented by STRING and GOrilla. Results: The first step we took was to assess the 196 AML cases that had a mutational profile available and observe the mutations that overlapped with TET2/IDH1/2/WT1 mutations. …”
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428por García-Pérez, Raquel, Esteller-Cucala, Paula, Mas, Glòria, Lobón, Irene, Di Carlo, Valerio, Riera, Meritxell, Kuhlwilm, Martin, Navarro, Arcadi, Blancher, Antoine, Di Croce, Luciano, Gómez-Skarmeta, José Luis, Juan, David, Marquès-Bonet, Tomàs“…Here, we extensively profiled a panel of human, chimpanzee, gorilla, orangutan, and macaque lymphoblastoid cell lines (LCLs), using ChIP-seq for five histone marks, ATAC-seq and RNA-seq, further complemented with whole genome sequencing (WGS) and whole genome bisulfite sequencing (WGBS). …”
Publicado 2021
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429por Lee, Maxwell Y., Metenou, Simon, Brough, Douglas E., Sabzevari, Helen, Bai, Ke, Jochems, Caroline, Schlom, Jeffrey, Allen, Clint T.“…The safety and efficacy of a novel gorilla adenovirus vaccine expressing a protein designed to elicit immune responses directed against HPV6 and HPV11, PRGN-2012, was studied using in vitro stimulation of T lymphocytes from patients with recurrent respiratory papillomatosis, in vivo vaccination studies, and therapeutic studies in mice bearing tumors expressing lrHPV antigen. …”
Publicado 2021
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430“…We investigated how different web-building platforms (Gorilla v.20190828, jsPsych v6.0.5, Lab.js v19.1.0, and psychoJS/PsychoPy3 v3.1.5), browsers (Chrome, Edge, Firefox, and Safari), and operating systems (macOS and Windows 10) impact display time across 30 different frame durations for each software combination. …”
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431“…Natural SARS-CoV-2 infections have been reported in domestic animals (dog, cat, and ferret), captive animals (tiger, lion, snow leopard, puma, otter, and gorilla), and wild and farmed minks. Vaccination of domestic animals can prevent the possible introduction of SARS-CoV-2 into the feral population and subsequent transmission to wildlife. …”
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432por Wroblewski, Emily E., Guethlein, Lisbeth A., Anderson, Aaron G., Liu, Weimin, Li, Yingying, Heisel, Sara E., Connell, Andrew Jesse, Ndjango, Jean-Bosco N., Bertolani, Paco, Hart, John A., Hart, Terese B., Sanz, Crickette M., Morgan, David B., Peeters, Martine, Sharp, Paul M., Hahn, Beatrice H., Parham, Peter“…Enriched in affected African populations, the B*53 variant of HLA-B, a cell surface protein that presents peptide antigens to cytotoxic lymphocytes, confers protection against severe malaria. Gorilla, chimpanzee, and bonobo are humans’ closest living relatives. …”
Publicado 2023
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433Publicado 1994Tabla de Contenidos: “…Povinelli -- Incipient mirror self-recognition in zoo gorillas and chimpanzees / Sue Taylor Parker -- Do gorillas recognize themselves on television? …”
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434“…Dalton and Fraenkel (2012, Cognition, 124, 367–372) were introducing “inattentional deafness” by showing that participants missed by 70% a voice repeatedly saying “I’m a Gorilla” when focusing on a primary conversation. …”
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435por Suresh, Hamsini, Crow, Megan, Jorstad, Nikolas, Hodge, Rebecca, Lein, Ed, Dobin, Alexander, Bakken, Trygve, Gillis, Jesse“…Here, we take advantage of single-cell expression data from the middle temporal gyrus of five primates (human, chimp, gorilla, macaque and marmoset) to identify 57 homologous cell types and generate cell type-specific gene co-expression networks for comparative analysis. …”
Publicado 2023
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436por Bodega, Beatrice, Cardone, Maria Francesca, Müller, Stefan, Neusser, Michaela, Orzan, Francesca, Rossi, Elena, Battaglioli, Elena, Marozzi, Anna, Riva, Paola, Rocchi, Mariano, Meneveri, Raffaella, Ginelli, Enrico“…RESULTS: A basic block consisting of short D4Z4 arrays (10–15 repeats), 4q35.2 specific sequences, and approximately 35 kb of interspersed repeats from different LINE subfamilies was repeated at least twice in the gorilla 4qter. This genomic organisation has undergone evolutionary remodelling, leading to the single representation of both the D4Z4 array and LINE block in chimpanzee, and the loss of the LINE block in humans. …”
Publicado 2007
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437por Muñoz-Fuentes, Violeta, Cacheiro, Pilar, Meehan, Terrence F., Aguilar-Pimentel, Juan Antonio, Brown, Steve D. M., Flenniken, Ann M., Flicek, Paul, Galli, Antonella, Mashhadi, Hamed Haseli, Hrabě de Angelis, Martin, Kim, Jong Kyoung, Lloyd, K. C. Kent, McKerlie, Colin, Morgan, Hugh, Murray, Stephen A., Nutter, Lauryl M. J., Reilly, Patrick T., Seavitt, John R., Seong, Je Kyung, Simon, Michelle, Wardle-Jones, Hannah, Mallon, Ann-Marie, Smedley, Damian, Parkinson, Helen E.“…While current bioinformatics efforts are focused on translating results to better understand human disease processes, IMPC data also aids understanding genetic function and processes in other species. Here we show, using gorilla genomic data, how genes essential to development in mice can be used to help assess the potentially deleterious impact of gene variants in other species. …”
Publicado 2018
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438por Negrey, Jacob D., Reddy, Rachna B., Scully, Erik J., Phillips-Garcia, Sarah, Owens, Leah A., Langergraber, Kevin E., Mitani, John C., Emery Thompson, Melissa, Wrangham, Richard W., Muller, Martin N., Otali, Emily, Machanda, Zarin, Hyeroba, David, Grindle, Kristine A., Pappas, Tressa E., Palmenberg, Ann C., Gern, James E., Goldberg, Tony L.“…Both viruses clustered phylogenetically within groups of known human variants, with MPV closely related to a lethal 2009 variant from mountain gorillas (Gorilla beringei beringei), suggesting two independent and simultaneous reverse zoonotic origins, either directly from humans or via intermediary hosts. …”
Publicado 2019
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439por Kwikiriza, Stuart, Stewart, Alex G., Mutahunga, Birungi, Dobson, Andrew E., Wilkinson, Ewan“…This exposes people and the wider environment, including the nearby world heritage site, home to the endangered mountain gorilla, to unnecessary risks. It is likely that the same is true in similar situations elsewhere. …”
Publicado 2019
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440por Demuth, Oliver E., Wiseman, Ashleigh L. A., van Beesel, Julia, Mallison, Heinrich, Hutchinson, John R.“…We created three-dimensional volumetric reconstructions for the hindlimb muscles of the extant Nile crocodile and extinct stem-archosaur Euparkeria, and the shoulder muscles of an extant gorilla to demonstrate the broad applicability of this methodology across living and extinct animal clades. …”
Publicado 2022
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